nimesulide has been researched along with Obesity in 4 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to examine how the COX-2 selective inhibitor nimesulide suppresses NAFLD in a murine model of high-fat diet (HFD)‑induced obesity." | 7.83 | Nimesulide, a cyclooxygenase-2 selective inhibitor, suppresses obesity-related non-alcoholic fatty liver disease and hepatic insulin resistance through the regulation of peroxisome proliferator-activated receptor γ. ( Harada, Y; Hisatome, I; Kishina, M; Koda, M; Tanaka, K; Tsujimoto, S; Yamamoto, Y; Yoshida, A, 2016) |
| " The aim of this study was to examine how the COX-2 selective inhibitor nimesulide suppresses NAFLD in a murine model of high-fat diet (HFD)‑induced obesity." | 3.83 | Nimesulide, a cyclooxygenase-2 selective inhibitor, suppresses obesity-related non-alcoholic fatty liver disease and hepatic insulin resistance through the regulation of peroxisome proliferator-activated receptor γ. ( Harada, Y; Hisatome, I; Kishina, M; Koda, M; Tanaka, K; Tsujimoto, S; Yamamoto, Y; Yoshida, A, 2016) |
| " The whole body insulin resistance of HFa indicated by the increased fasting plasma insulin levels and the elevated area under curve of insulin obtained from the oral glucose tolerance test were significantly reversed in those combined with celecoxib and nimesulid administration compared with those in HFr." | 3.77 | The importance of cyclooxygenase 2-mediated oxidative stress in obesity-induced muscular insulin resistance in high-fat-fed rats. ( Chen, CH; Hsia, TL; Hsieh, CH; Hsieh, PS; Huang, DW; Tian, YF, 2011) |
| "Body weight was increased significantly and similarly in HFa, HFa-Cel, and HFa-Mes." | 1.35 | COX-2-mediated inflammation in fat is crucial for obesity-linked insulin resistance and fatty liver. ( Chan, PC; Chen, CH; Chiang, CF; Hsieh, PS; Jin, JS; Shih, KC, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsujimoto, S | 1 |
| Kishina, M | 1 |
| Koda, M | 1 |
| Yamamoto, Y | 1 |
| Tanaka, K | 1 |
| Harada, Y | 1 |
| Yoshida, A | 1 |
| Hisatome, I | 1 |
| Hsieh, PS | 3 |
| Jin, JS | 1 |
| Chiang, CF | 2 |
| Chan, PC | 1 |
| Chen, CH | 3 |
| Shih, KC | 1 |
| Lu, KC | 1 |
| Tian, YF | 1 |
| Hsia, TL | 1 |
| Hsieh, CH | 1 |
| Huang, DW | 1 |
4 other studies available for nimesulide and Obesity
| Article | Year |
|---|---|
Nimesulide, a cyclooxygenase-2 selective inhibitor, suppresses obesity-related non-alcoholic fatty liver disease and hepatic insulin resistance through the regulation of peroxisome proliferator-activated receptor γ.
Topics: Animals; Chemokine CCL2; Collagen Type I; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diet, High- | 2016 |
COX-2-mediated inflammation in fat is crucial for obesity-linked insulin resistance and fatty liver.
Topics: Adipocytes; Adipogenesis; Adipose Tissue; Animals; Blood Glucose; Body Weight; Celecoxib; Cell Size; | 2009 |
Suppressive effect of COX2 inhibitor on the progression of adipose inflammation in high-fat-induced obese rats.
Topics: Adiposity; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blood Glucose; Blood Pr | 2010 |
The importance of cyclooxygenase 2-mediated oxidative stress in obesity-induced muscular insulin resistance in high-fat-fed rats.
Topics: Adipose Tissue; Animals; Biomarkers; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diet, R | 2011 |