nimesulide has been researched along with Liver Failure, Acute in 17 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 49-year-old woman presented at the emergency department, with acute hepatic failure, 2 weeks after taking nimesulide." | 3.83 | Autoimmune hepatitis unmasked by nimesulide. ( Brandão, I; Caridade, S; Fonseca, M; Magalhães, R, 2016) |
| "Nimesulide is a non-steroidal anti-inflammatory drug available in several European countries." | 2.44 | [Acute liver failure due to a treatment by nimesulide: another case and review]. ( Baillon, JJ; Ber, CE; Christin, F; Delafosse, B; Dumortier, J; Hayi-Slayman, D; Page, M; Rimmelé, T, 2008) |
| "Nimesulide is a non-steroidal anti-inflammatory drug still marketed in many countries." | 1.62 | Serious liver injury induced by Nimesulide: an international collaborative study. ( Alvarez-Alvarez, I; Anders, M; Andrade, RJ; Arrese, M; Bessone, F; Carrilho, F; Colombato, L; Fainboim, H; Fassio, E; Gualano, G; Hernandez, N; Lucena, MI; Medina-Caliz, I; Mendizabal, M; Niu, H; Ono, SK; Parana, R; Peralta, M; Reggiardo, MV; Ridruejo, E; Robles-Diaz, M; Stephens, C; Tanno, F; Tanno, H, 2021) |
| "Nimesulide was assessed as probably associated with liver injury in all six cases." | 1.35 | Nimesulide associated fulminant hepatic failure. ( Kennedy, F; McCormick, PA; Niamh, N; Walker, SL, 2008) |
| "Nimesulide is an NSAID, with cox-2 preference, which has been reported to cause death from hepatic failure." | 1.34 | Nimesulide-induced hepatotoxicity and fatal hepatic failure. ( Chow, WC; Lai, SH; Ong, WM; Tan, HH, 2007) |
| "Nimesulide may cause liver damage." | 1.30 | Nimesulide-induced hepatitis and acute liver failure. ( Bar-Meir, S; Brickman, CM; Bruck, R; Farfel, Z; Hassin, D; Mouallem, M; Tanay, A; Weiss, P, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 11 (64.71) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Bessone, F | 1 |
| Hernandez, N | 1 |
| Mendizabal, M | 1 |
| Ridruejo, E | 1 |
| Gualano, G | 1 |
| Fassio, E | 1 |
| Peralta, M | 1 |
| Fainboim, H | 1 |
| Anders, M | 1 |
| Tanno, H | 1 |
| Tanno, F | 1 |
| Parana, R | 1 |
| Medina-Caliz, I | 1 |
| Robles-Diaz, M | 1 |
| Alvarez-Alvarez, I | 1 |
| Niu, H | 1 |
| Stephens, C | 1 |
| Colombato, L | 1 |
| Arrese, M | 1 |
| Reggiardo, MV | 1 |
| Ono, SK | 1 |
| Carrilho, F | 1 |
| Lucena, MI | 2 |
| Andrade, RJ | 2 |
| Kwon, J | 1 |
| Kim, S | 1 |
| Yoo, H | 1 |
| Lee, E | 1 |
| Magalhães, R | 1 |
| Fonseca, M | 1 |
| Brandão, I | 1 |
| Caridade, S | 1 |
| Page, M | 1 |
| Christin, F | 1 |
| Hayi-Slayman, D | 1 |
| Baillon, JJ | 1 |
| Ber, CE | 1 |
| Delafosse, B | 1 |
| Dumortier, J | 1 |
| Rimmelé, T | 1 |
| Betrosian, AP | 1 |
| Flevari, K | 1 |
| Andrianakis, I | 1 |
| Boudouri, I | 1 |
| Douzinas, EE | 1 |
| Walker, SL | 1 |
| Kennedy, F | 1 |
| Niamh, N | 1 |
| McCormick, PA | 1 |
| Bissoli, F | 3 |
| Altwegg, R | 1 |
| Abenavoli, L | 1 |
| Libri, E | 1 |
| Bosco, D | 1 |
| Gallo, D | 1 |
| Luzza, F | 1 |
| Rodrigo, L | 1 |
| de Francisco, R | 1 |
| Pérez-Pariente, JM | 1 |
| Cadahia, V | 1 |
| Tojo, R | 1 |
| Rodriguez, M | 1 |
| Tan, HH | 1 |
| Ong, WM | 1 |
| Lai, SH | 1 |
| Chow, WC | 1 |
| Dastis, SN | 1 |
| Rahier, J | 1 |
| Lerut, J | 1 |
| Geubel, AP | 1 |
| Weiss, P | 2 |
| Mouallem, M | 1 |
| Bruck, R | 1 |
| Hassin, D | 1 |
| Tanay, A | 1 |
| Brickman, CM | 1 |
| Farfel, Z | 1 |
| Bar-Meir, S | 1 |
| Stadlmann, S | 1 |
| Zoller, H | 1 |
| Vogel, W | 1 |
| Offner, FA | 1 |
3 reviews available for nimesulide and Liver Failure, Acute
| Article | Year |
|---|---|
Nimesulide-induced hepatotoxicity: A systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Female; Humans; Liv | 2019 |
[Acute liver failure due to a treatment by nimesulide: another case and review].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Liver Failure, Acute; Middle Aged; Sulfonam | 2008 |
[Drug-induced liver injury].
Topics: Acetaminophen; Algorithms; Amoxicillin; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Anti-Bact | 2012 |
14 other studies available for nimesulide and Liver Failure, Acute
| Article | Year |
|---|---|
Serious liver injury induced by Nimesulide: an international collaborative study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Bilirubin; Chem | 2021 |
Autoimmune hepatitis unmasked by nimesulide.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Hepatitis, Autoimmune; Humans; Liver; Liver Cirrhos | 2016 |
Severe hemolytic anemia and fatal hepatic failure associated with nimesulide.
Topics: Anemia, Hemolytic; Anti-Inflammatory Agents, Non-Steroidal; Fatal Outcome; Female; Humans; Liver Fai | 2009 |
Nimesulide associated fulminant hepatic failure.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ireland; Liver Failure, Acute; Liver Transp | 2008 |
Negrin Dastis S. et al.: Liver transplantation for nonsteroidal anti-inflammatory drug-induced liver failure: nimesulide as the first implicated compound. Eur J Gastroenterol Hepatol 2007; 19:919-922.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Liver Failure, Acute; Liver Transplantation; Sulfon | 2008 |
Comment on: severe hemolytic anemia and fatal hepatic failure associated with nimesulide.
Topics: Anemia, Hemolytic; Anti-Inflammatory Agents, Non-Steroidal; Causality; Drug-Related Side Effects and | 2009 |
[Acute liver failure due to a treatment by nimesulide].
Topics: Amoxicillin-Potassium Clavulanate Combination; Anesthetics, Inhalation; Anti-Bacterial Agents; Anti- | 2009 |
Nimesulide-induced severe hemolytic anemia and acute liver failure leading to liver transplantation.
Topics: Anemia, Hemolytic; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Liver Failure, Acute; Li | 2002 |
Nimesulide-induced hepatotoxicity and fatal hepatic failure.
Topics: Aged; Cyclooxygenase 2 Inhibitors; Drug-Related Side Effects and Adverse Reactions; Fatal Outcome; F | 2007 |
Liver transplantation for nonsteroidal anti-inflammatory drug-induced liver failure: nimesulide as the first implicated compound.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Chemical and Drug Induced Liver Injury; F | 2007 |
Nimesulide-induced hepatotoxicity and fatal hepatic failure.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Humans; Liver Failu | 2008 |
Nimesulide-induced hepatitis and acute liver failure.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Chemical and Drug Induc | 1999 |
Nimesulide-induced hepatitis and acute liver failure.
Topics: Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Bl | 1999 |
COX-2 inhibitor (nimesulide) induced acute liver failure.
Topics: Adult; Biopsy; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diagnosis, | 2002 |