nimesulide has been researched along with Intestinal Diseases in 2 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
Intestinal Diseases: Pathological processes in any segment of the INTESTINE from DUODENUM to RECTUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indomethacin was associated with electron microscopy changes suggestive of uncoupling in 60%-70% of enterocytes examined, whereas nimesulide affected 10%-30% of enterocytes, depending on the dose." | 1.30 | Comparison of indomethacin and nimesulide, a selective cyclooxygenase-2 inhibitor, on key pathophysiologic steps in the pathogenesis of nonsteroidal anti-inflammatory drug enteropathy in the rat. ( Bjarnason, I; Foster, R; Jacob, M; Mahmud, T; Rafi, S; Roseth, A; Sigthorsson, G; Simpson, R; Somasundaram, S; Tavares, I; Wrigglesworth, J, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gan, HT | 1 |
| Pasricha, PJ | 1 |
| Chen, JD | 1 |
| Sigthorsson, G | 1 |
| Jacob, M | 1 |
| Wrigglesworth, J | 1 |
| Somasundaram, S | 1 |
| Tavares, I | 1 |
| Foster, R | 1 |
| Roseth, A | 1 |
| Rafi, S | 1 |
| Mahmud, T | 1 |
| Simpson, R | 1 |
| Bjarnason, I | 1 |
2 other studies available for nimesulide and Intestinal Diseases
| Article | Year |
|---|---|
Blockade of p38 mitogen-activated protein kinase pathway ameliorates delayed intestinal transit in burned rats.
Topics: Animals; Burns; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Enzyme Inhibitors; Gastrointest | 2007 |
Comparison of indomethacin and nimesulide, a selective cyclooxygenase-2 inhibitor, on key pathophysiologic steps in the pathogenesis of nonsteroidal anti-inflammatory drug enteropathy in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Membrane Permeability; Cyclooxygenase Inhibit | 1998 |