nimesulide has been researched along with Insulin Resistance in 4 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to examine how the COX-2 selective inhibitor nimesulide suppresses NAFLD in a murine model of high-fat diet (HFD)‑induced obesity." | 7.83 | Nimesulide, a cyclooxygenase-2 selective inhibitor, suppresses obesity-related non-alcoholic fatty liver disease and hepatic insulin resistance through the regulation of peroxisome proliferator-activated receptor γ. ( Harada, Y; Hisatome, I; Kishina, M; Koda, M; Tanaka, K; Tsujimoto, S; Yamamoto, Y; Yoshida, A, 2016) |
| " The aim of this study was to examine how the COX-2 selective inhibitor nimesulide suppresses NAFLD in a murine model of high-fat diet (HFD)‑induced obesity." | 3.83 | Nimesulide, a cyclooxygenase-2 selective inhibitor, suppresses obesity-related non-alcoholic fatty liver disease and hepatic insulin resistance through the regulation of peroxisome proliferator-activated receptor γ. ( Harada, Y; Hisatome, I; Kishina, M; Koda, M; Tanaka, K; Tsujimoto, S; Yamamoto, Y; Yoshida, A, 2016) |
| " The whole body insulin resistance of HFa indicated by the increased fasting plasma insulin levels and the elevated area under curve of insulin obtained from the oral glucose tolerance test were significantly reversed in those combined with celecoxib and nimesulid administration compared with those in HFr." | 3.77 | The importance of cyclooxygenase 2-mediated oxidative stress in obesity-induced muscular insulin resistance in high-fat-fed rats. ( Chen, CH; Hsia, TL; Hsieh, CH; Hsieh, PS; Huang, DW; Tian, YF, 2011) |
| "Nimesulide treatment improved insulin sensitivity and glycemic control, increased GLP-1, decreased liver lipids and improved FGF-21 in serum." | 1.72 | In vivo antidiabetic activity of nimesulide due to inhibition of amino acid transport. ( Jain, M; Joharapurkar, A; Kshirsagar, S; Patel, M; Patel, V; Savsani, H, 2022) |
| "Body weight was increased significantly and similarly in HFa, HFa-Cel, and HFa-Mes." | 1.35 | COX-2-mediated inflammation in fat is crucial for obesity-linked insulin resistance and fatty liver. ( Chan, PC; Chen, CH; Chiang, CF; Hsieh, PS; Jin, JS; Shih, KC, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Joharapurkar, A | 1 |
| Kshirsagar, S | 1 |
| Patel, V | 1 |
| Patel, M | 1 |
| Savsani, H | 1 |
| Jain, M | 1 |
| Tsujimoto, S | 1 |
| Kishina, M | 1 |
| Koda, M | 1 |
| Yamamoto, Y | 1 |
| Tanaka, K | 1 |
| Harada, Y | 1 |
| Yoshida, A | 1 |
| Hisatome, I | 1 |
| Hsieh, PS | 2 |
| Jin, JS | 1 |
| Chiang, CF | 1 |
| Chan, PC | 1 |
| Chen, CH | 2 |
| Shih, KC | 1 |
| Tian, YF | 1 |
| Hsia, TL | 1 |
| Hsieh, CH | 1 |
| Huang, DW | 1 |
4 other studies available for nimesulide and Insulin Resistance
| Article | Year |
|---|---|
In vivo antidiabetic activity of nimesulide due to inhibition of amino acid transport.
Topics: Amino Acid Transport Systems, Neutral; Amino Acids; Animals; Biological Transport; Dose-Response Rel | 2022 |
Nimesulide, a cyclooxygenase-2 selective inhibitor, suppresses obesity-related non-alcoholic fatty liver disease and hepatic insulin resistance through the regulation of peroxisome proliferator-activated receptor γ.
Topics: Animals; Chemokine CCL2; Collagen Type I; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diet, High- | 2016 |
COX-2-mediated inflammation in fat is crucial for obesity-linked insulin resistance and fatty liver.
Topics: Adipocytes; Adipogenesis; Adipose Tissue; Animals; Blood Glucose; Body Weight; Celecoxib; Cell Size; | 2009 |
The importance of cyclooxygenase 2-mediated oxidative stress in obesity-induced muscular insulin resistance in high-fat-fed rats.
Topics: Adipose Tissue; Animals; Biomarkers; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diet, R | 2011 |