nimesulide and Infarction, Middle Cerebral Artery studies

nimesulide and Infarction, Middle Cerebral Artery

nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.

Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.

Research Excerpts

Excerpt	Relevance	Reference
" The purpose of this study was to evaluate the neuroprotective effects of the selective COX-2 inhibitor nimesulide on cerebral infarction and neurological deficits in a standardized model of transient focal cerebral ischemia in rats."	3.72	Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat. ( Candelario-Jalil, E; Fiebich, BL; García-Cabrera, M; González-Falcón, A; León, OS, 2004)

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

2 (100.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Candelario-Jalil, E	2
González-Falcón, A	2
García-Cabrera, M	2
León, OS	2
Fiebich, BL	2

Studies

Candelario-Jalil, E

González-Falcón, A

García-Cabrera, M

León, OS

Fiebich, BL

Other Studies

2 other studies available for nimesulide and Infarction, Middle Cerebral Artery

Article	Year
Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat. Brain research, 2004, May-08, Volume: 1007, Issue:1-2 Topics: Analysis of Variance; Animals; Behavior, Animal; Cerebral Infarction; Dinoprostone; Disease Models,	2004
Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats. Journal of neurochemistry, 2007, Volume: 100, Issue:4 Topics: Animals; Blood-Brain Barrier; Enzyme Inhibitors; Infarction, Middle Cerebral Artery; Leukocytes; Mal	2007

Article

Year

Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat.

Brain research, 2004, May-08, Volume: 1007, Issue:1-2

Topics: Analysis of Variance; Animals; Behavior, Animal; Cerebral Infarction; Dinoprostone; Disease Models,

2004

Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats.

Journal of neurochemistry, 2007, Volume: 100, Issue:4

Topics: Animals; Blood-Brain Barrier; Enzyme Inhibitors; Infarction, Middle Cerebral Artery; Leukocytes; Mal

2007