Page last updated: 2024-11-01

nimesulide and Granuloma

nimesulide has been researched along with Granuloma in 3 studies

nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.

Granuloma: A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.

Research Excerpts

ExcerptRelevanceReference
" Moreover, nanoencapsulation significantly increased the anti-inflammatory activity of nimesulide in two chronic inflammation models (chronic arthritis and granuloma)."3.78Semi-solid topical formulations containing nimesulide-loaded nanocapsules showed in-vivo anti-inflammatory activity in chronic arthritis and fibrovascular tissue models. ( Alves, MP; Guterres, SS; Lenz, QF; Pohlmann, A, 2012)
"In this model of chronic inflammation, aspirin, more selective for the inhibition of COX-1 is more effective than the selective COX-2 inhibitors nimesulide and NS-398 at inhibiting granuloma dry weight, vascularity and COX activity."3.70Differential effects of inhibition of isoforms of cyclooxygenase (COX-1, COX-2) in chronic inflammation. ( Gilroy, DW; Tomlinson, A; Willoughby, DA, 1998)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lenz, QF1
Guterres, SS1
Pohlmann, A1
Alves, MP1
Gilroy, DW1
Tomlinson, A1
Willoughby, DA1
Tanaka, K1
Shimotori, T1
Makino, S1
Aikawa, Y1
Inaba, T1
Yoshida, C1
Takano, S1

Other Studies

3 other studies available for nimesulide and Granuloma

ArticleYear
Semi-solid topical formulations containing nimesulide-loaded nanocapsules showed in-vivo anti-inflammatory activity in chronic arthritis and fibrovascular tissue models.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2012, Volume: 61, Issue:4

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental;

2012
Differential effects of inhibition of isoforms of cyclooxygenase (COX-1, COX-2) in chronic inflammation.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1998, Volume: 47, Issue:2

    Topics: Air; Air Sacs; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Croton Oil; Cyclooxygenase

1998
Pharmacological studies of the new antiinflammatory agent 3-formylamino-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-o ne. 1st communication: antiinflammatory, analgesic and other related properties.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzopyrans; Dogs; Edema;

1992