nimesulide has been researched along with Gastric Ulcer in 12 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The diagnosis of toxic hepatitis due to nimesulide was supported by the time-course of drug usage, sex, age, absence of other causes of liver disease, a compatible liver biopsy and the improvement after drug withdrawal." | 5.31 | [Bleeding gastric ulcers and acute hepatitis: 2 simultaneous adverse reactions due to nimesulide in a case]. ( Meneses, M; Reyes, H; Tejos, S; Torrejón, N, 2000) |
| " The results revealed that 100 mg/kg nimesulide produces gastric ulceration in adrenalectomized rats, which is prevented by prednisolone and adrenaline." | 3.74 | Indirect role of alpha2-adrenoreceptors in anti-ulcer effect mechanism of nimesulide in rats. ( Cadirci, E; Gocer, F; Hacimuftuoglu, A; Halici, Z; Keles, S; Suleyman, H, 2007) |
| "Tizanidine, an alpha2-adrenergic receptor agonist with myospasmolytic action, is indicated for the treatment of back pain either as monotherapy or in combination with nonsteridal anti-inflammatory drugs (NSAIDs)." | 3.71 | Modulation of NSAID-induced antinociceptive and anti-inflammatory effects by alpha2-adrenoceptor agonists with gastroprotective effects. ( Jain, NK; Kulkarni, SK; Singh, A, 2002) |
| "The diagnosis of toxic hepatitis due to nimesulide was supported by the time-course of drug usage, sex, age, absence of other causes of liver disease, a compatible liver biopsy and the improvement after drug withdrawal." | 1.31 | [Bleeding gastric ulcers and acute hepatitis: 2 simultaneous adverse reactions due to nimesulide in a case]. ( Meneses, M; Reyes, H; Tejos, S; Torrejón, N, 2000) |
| "Pretreatment with indomethacin (10 mg kg[-1], s." | 1.30 | Cyclo-oxygenase isozymes in mucosal ulcergenic and functional responses following barrier disruption in rat stomachs. ( Hirata, T; Kato, S; Takeuchi, K; Ukawa, H; Yamakuni, H, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 8 (66.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lino, RC | 1 |
| da Silva, DPB | 1 |
| Florentino, IF | 1 |
| da Silva, DM | 1 |
| Martins, JLR | 1 |
| Batista, DDC | 1 |
| Leite, KCS | 1 |
| Villavicencio, B | 1 |
| Vasconcelos, GA | 1 |
| Silva, ALP | 1 |
| de Ávila, RI | 1 |
| Verli, H | 1 |
| Valadares, MC | 1 |
| Gil, ES | 1 |
| Vaz, BG | 1 |
| Lião, LM | 1 |
| Menegatti, R | 1 |
| Costa, EA | 1 |
| Varvanina, GG | 1 |
| Tkachenko, EV | 1 |
| Drozdov, VN | 1 |
| Trubitsyna, IE | 1 |
| Jain, NK | 1 |
| Kulkarni, SK | 1 |
| Singh, A | 1 |
| Gambero, A | 1 |
| Maróstica, M | 1 |
| Becker, TL | 1 |
| Pedrazzoli, J | 1 |
| Suleyman, H | 3 |
| Halici, Z | 2 |
| Cadirci, E | 2 |
| Hacimuftuoglu, A | 1 |
| Keles, S | 1 |
| Gocer, F | 1 |
| Albayrak, A | 1 |
| Hirata, T | 1 |
| Ukawa, H | 1 |
| Yamakuni, H | 1 |
| Kato, S | 1 |
| Takeuchi, K | 1 |
| Guslandi, M | 1 |
| Foppa, L | 1 |
| Fanti, L | 1 |
| Sorghi, M | 1 |
| Kataoka, H | 1 |
| Horie, Y | 1 |
| Koyama, R | 1 |
| Nakatsugi, S | 1 |
| Furukawa, M | 1 |
| Tejos, S | 1 |
| Torrejón, N | 1 |
| Reyes, H | 1 |
| Meneses, M | 1 |
| Akçay, F | 1 |
| Altinkaynak, K | 1 |
| Tanaka, K | 1 |
| Shimotori, T | 1 |
| Makino, S | 1 |
| Aikawa, Y | 1 |
| Inaba, T | 1 |
| Yoshida, C | 1 |
| Takano, S | 1 |
1 review available for nimesulide and Gastric Ulcer
| Article | Year |
|---|---|
Nimesulide is a selective COX-2 inhibitory, atypical non-steroidal anti-inflammatory drug.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Humans; Stomach Ulcer; Structure | 2008 |
11 other studies available for nimesulide and Gastric Ulcer
| Article | Year |
|---|---|
Pharmacological evaluation and molecular docking of new di-tert-butylphenol compound, LQFM-091, a new dual 5-LOX/COX inhibitor.
Topics: 3T3 Cells; Animals; Carrageenan; Cell Survival; Cyclooxygenase Inhibitors; Cytokines; Edema; Female; | 2017 |
[Experimental NSAID-associated gastric mucosa injuries].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Disease Models | 2008 |
Modulation of NSAID-induced antinociceptive and anti-inflammatory effects by alpha2-adrenoceptor agonists with gastroprotective effects.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Drug Synergi | 2002 |
Effect of different cyclooxygenase inhibitors on gastric adaptive cytoprotection induced by 20% ethanol.
Topics: Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cytoprotection; D | 2007 |
Indirect role of alpha2-adrenoreceptors in anti-ulcer effect mechanism of nimesulide in rats.
Topics: Adrenalectomy; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; alpha- | 2007 |
Cyclo-oxygenase isozymes in mucosal ulcergenic and functional responses following barrier disruption in rat stomachs.
Topics: Animals; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenas | 1997 |
Nonsteroidal anti-inflammatory drugs and gastric mucosal blood flow.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Blood Flow Velocity; Diclo | 1999 |
Interaction between NSAIDs and steroid in rat stomach: safety of nimesulide as a preferential COX-2 inhibitor in the stomach.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cycloo | 2000 |
[Bleeding gastric ulcers and acute hepatitis: 2 simultaneous adverse reactions due to nimesulide in a case].
Topics: Acute Disease; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury | 2000 |
The effect of nimesulide on the indomethacin- and ethanol-induced gastric ulcer in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, | 2002 |
Pharmacological studies of the new antiinflammatory agent 3-formylamino-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-o ne. 1st communication: antiinflammatory, analgesic and other related properties.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzopyrans; Dogs; Edema; | 1992 |