Page last updated: 2024-11-01

nimesulide and Esophageal Neoplasms

nimesulide has been researched along with Esophageal Neoplasms in 7 studies

nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.

Esophageal Neoplasms: Tumors or cancer of the ESOPHAGUS.

Research Excerpts

ExcerptRelevanceReference
"In the control group, esophagitis, Barrett's esophagus (BE) and adenocarcinoma (EAC) were observed, and the frequency of these conditions increased with time."5.34[Cyclooxygenase (COX)-2 expression in a rat duodenoesophageal reflux model and chemoprevention of adenocarcinoma by the selective COX-2 inhibitor nimesulide]. ( Fujimura, T; Fushida, S; Kinami, S; Miyashita, T; Ninomiya, I; Ohta, T; Oyama, K, 2007)
"Pretreatment with aspirin and nimesulide inhibited EC9706 and EC109 cell growth in a time and dose-dependent manner, accompanied with a decrease of prostaglandin E2 production."1.35Effects of cyclooxygenase-2 non-selective and selective inhibitors on proliferation inhibition and apoptosis induction of esophageal squamous carcinoma cells. ( Cho, CH; Li, P; Liu, X; Wu, YD; Xu, CM; Yu, ZL; Zhang, ST, 2009)
"The esophageal squamous carcinoma cell line (TE-13) was treated with different concentrations of nicotine (100 microg/mL and 200 microg/mL) or 200 microg/mL nicotine plus 100 micromol/L nimesulide."1.35Nicotine enhances migration and invasion of human esophageal squamous carcinoma cells which is inhibited by nimesulide. ( Zhang, ST; Zhu, ST; Zong, Y, 2009)
"In the control group, esophagitis, Barrett's esophagus (BE) and adenocarcinoma (EAC) were observed, and the frequency of these conditions increased with time."1.34[Cyclooxygenase (COX)-2 expression in a rat duodenoesophageal reflux model and chemoprevention of adenocarcinoma by the selective COX-2 inhibitor nimesulide]. ( Fujimura, T; Fushida, S; Kinami, S; Miyashita, T; Ninomiya, I; Ohta, T; Oyama, K, 2007)
"The incidence of oesophageal cancer (OC) has risen in recent decades, with survival rates remaining poor despite surgical treatment and adjuvant chemotherapy."1.34Cyclooxygenase-2 inhibitors demonstrate anti-proliferative effects in oesophageal cancer cells by prostaglandin E(2)-independent mechanisms. ( Deasy, BM; McKenna, SL; O'Donovan, TR; O'Sullivan, GC; O'Sullivan-Coyne, G, 2007)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (85.71)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, JR1
Wu, WJ1
Liu, SX1
Zuo, LF1
Wang, Y1
Yang, JZ1
Nan, YM1
Li, P3
Zhang, ST4
Yu, ZL2
Wu, YD1
Liu, X2
Xu, CM1
Cho, CH2
Zong, Y1
Zhu, ST1
Wu, WK1
Wong, HP1
Yu, L1
Oyama, K1
Fujimura, T1
Ninomiya, I1
Miyashita, T1
Kinami, S1
Fushida, S1
Ohta, T1
Deasy, BM1
O'Sullivan-Coyne, G1
O'Donovan, TR1
McKenna, SL1
O'Sullivan, GC1
You, H1
Jia, JD1

Other Studies

7 other studies available for nimesulide and Esophageal Neoplasms

ArticleYear
Nimesulide inhibits the growth of human esophageal carcinoma cells by inactivating the JAK2/STAT3 pathway.
    Pathology, research and practice, 2015, Volume: 211, Issue:6

    Topics: Animals; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2

2015
Effects of cyclooxygenase-2 non-selective and selective inhibitors on proliferation inhibition and apoptosis induction of esophageal squamous carcinoma cells.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2009, Volume: 22, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; bcl-2-Associated X Protein; Blotting, W

2009
Nicotine enhances migration and invasion of human esophageal squamous carcinoma cells which is inhibited by nimesulide.
    World journal of gastroenterology, 2009, May-28, Volume: 15, Issue:20

    Topics: Calcium Channel Blockers; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cyclooxygenase

2009
Chloroform extract of cigarette smoke induces proliferation of human esophageal squamous-cell carcinoma cells: modulation by beta-adrenoceptors.
    Drug and chemical toxicology, 2009, Volume: 32, Issue:3

    Topics: Adrenergic beta-Antagonists; Atenolol; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferatio

2009
[Cyclooxygenase (COX)-2 expression in a rat duodenoesophageal reflux model and chemoprevention of adenocarcinoma by the selective COX-2 inhibitor nimesulide].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2007, Volume: 104, Issue:8

    Topics: Adenocarcinoma; Animals; Barrett Esophagus; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprost

2007
Cyclooxygenase-2 inhibitors demonstrate anti-proliferative effects in oesophageal cancer cells by prostaglandin E(2)-independent mechanisms.
    Cancer letters, 2007, Oct-28, Volume: 256, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; C

2007
COX-2 mRNA expression in esophageal squamous cell carcinoma (ESCC) and effect by NSAID.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2008, Volume: 21, Issue:1

    Topics: Aspirin; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxyg

2008