nimesulide has been researched along with Colitis in 11 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We compared the effects of nimesulide, a preferential COX-2 inhibitor, with those of indomethacin, acetylsalicylic acid (ASA), and dexamethasone in a 24-h model of 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis in the rat." | 7.71 | Effects of a COX-2 preferential agent nimesulide on TNBS-induced acute inflammation in the gut. ( Kankuri, E; Korpela, R; Moilanen, E; Paakkari, I; Vaali, K; Vapaatalo, H, 2001) |
| "Chronic colitis was induced in mice by four cycles of administration of dextran sulfate sodium (DSS) (i." | 5.35 | Effects of nimesulide, a cyclooxygenase-2 selective inhibitor, on colitis induced tumors. ( Hirata, I; Inoue, T; Murano, M, 2008) |
| "Acute colitis was induced by exposing female ICR mice to 5% DSS in drinking water for 1 week." | 5.32 | Suppression of dextran sodium sulfate-induced colitis in mice by zerumbone, a subtropical ginger sesquiterpene, and nimesulide: separately and in combination. ( Hayashi, R; Kwon, KH; Murakami, A; Ohigashi, H; Safitri, R; Takana, T; Tanaka, T, 2003) |
| "Female CD-1 (ICR) mice were given a single intraperitoneal administration of AOM (10 mg/kg body weight) and followed by one-week oral exposure of 2% (w/v) DSS in drinking water, and then maintained on the basal diets mixed with or without nimesulide (0." | 3.73 | Suppression of colitis-related mouse colon carcinogenesis by a COX-2 inhibitor and PPAR ligands. ( Kohno, H; Sugie, S; Suzuki, R; Tanaka, T, 2005) |
| " Celecoxib (10, 20 and 40 mg/kg(-l)) was significantly more potent at aggravating ischemia-reperfusion injury as compared to nimesulide." | 3.73 | Comparative gastrointestinal toxicity of selective cyclooxygenase (COX-2) inhibitors. ( Malhotra, S; Nada, R; Pandhi, P; Shafiq, N, 2005) |
| " We compared the effects of nimesulide, a preferential COX-2 inhibitor, with those of indomethacin, acetylsalicylic acid (ASA), and dexamethasone in a 24-h model of 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis in the rat." | 3.71 | Effects of a COX-2 preferential agent nimesulide on TNBS-induced acute inflammation in the gut. ( Kankuri, E; Korpela, R; Moilanen, E; Paakkari, I; Vaali, K; Vapaatalo, H, 2001) |
| "Nimesulide significantly decreased the extent of colitis induced by acetic acid." | 3.70 | Cyclo-oxygenase-2 inhibitors ameliorate the severity of experimental colitis in rats. ( Cohen, P; Karmeli, F; Rachmilewitz, D, 2000) |
| "Anandamide was protective in the explant colitis model; however COX-2 inhibition did not alter its effects, associated with a lack of COX-2 induction in explant mucosal tissue." | 1.39 | Prostaglandin ethanolamides attenuate damage in a human explant colitis model. ( Harvey, BS; Nicotra, LL; Smid, SD; Vu, M, 2013) |
| "Chronic colitis was induced in mice by four cycles of administration of dextran sulfate sodium (DSS) (i." | 1.35 | Effects of nimesulide, a cyclooxygenase-2 selective inhibitor, on colitis induced tumors. ( Hirata, I; Inoue, T; Murano, M, 2008) |
| "Acute colitis was induced by exposing female ICR mice to 5% DSS in drinking water for 1 week." | 1.32 | Suppression of dextran sodium sulfate-induced colitis in mice by zerumbone, a subtropical ginger sesquiterpene, and nimesulide: separately and in combination. ( Hayashi, R; Kwon, KH; Murakami, A; Ohigashi, H; Safitri, R; Takana, T; Tanaka, T, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (90.91) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nicotra, LL | 1 |
| Vu, M | 1 |
| Harvey, BS | 1 |
| Smid, SD | 1 |
| Murakami, A | 1 |
| Hayashi, R | 1 |
| Tanaka, T | 2 |
| Kwon, KH | 1 |
| Ohigashi, H | 1 |
| Safitri, R | 1 |
| Takana, T | 1 |
| d'Halluin, PN | 1 |
| Turlin, B | 1 |
| Polard, E | 1 |
| Dinasquet, M | 1 |
| Pagenault, M | 1 |
| Rioux, N | 1 |
| Gosselin, M | 1 |
| Bretagne, JF | 1 |
| Heresbach, D | 1 |
| Kohno, H | 1 |
| Suzuki, R | 1 |
| Sugie, S | 1 |
| Shafiq, N | 1 |
| Malhotra, S | 1 |
| Pandhi, P | 1 |
| Nada, R | 1 |
| Inoue, T | 1 |
| Hirata, I | 1 |
| Murano, M | 1 |
| Karmeli, F | 1 |
| Cohen, P | 1 |
| Rachmilewitz, D | 1 |
| Tardieu, D | 1 |
| Jaeg, JP | 1 |
| Deloly, A | 1 |
| Corpet, DE | 1 |
| Cadet, J | 1 |
| Petit, CR | 1 |
| Oktar, BK | 1 |
| Ercan, F | 1 |
| Yeğen, BC | 1 |
| Alican, I | 1 |
| Guo, X | 1 |
| Liu, ES | 1 |
| Ko, JK | 1 |
| Wong, BC | 1 |
| Ye, Y | 1 |
| Lam, S | 1 |
| Cho, C | 1 |
| Kankuri, E | 1 |
| Vaali, K | 1 |
| Korpela, R | 1 |
| Paakkari, I | 1 |
| Vapaatalo, H | 1 |
| Moilanen, E | 1 |
1 review available for nimesulide and Colitis
| Article | Year |
|---|---|
[Selective COX-2 inhibitor-associated colitis: two case reports].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis; Cyclooxygenase Inhibitors; Female; Humans; Meloxic | 2003 |
10 other studies available for nimesulide and Colitis
| Article | Year |
|---|---|
Prostaglandin ethanolamides attenuate damage in a human explant colitis model.
Topics: Adult; Amides; Arachidonic Acids; Bimatoprost; Cloprostenol; Colitis; Colon, Sigmoid; Cyclooxygenase | 2013 |
Suppression of dextran sodium sulfate-induced colitis in mice by zerumbone, a subtropical ginger sesquiterpene, and nimesulide: separately and in combination.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Dextran Sulfate; Disease Models, Animal; | 2003 |
Suppression of colitis-related mouse colon carcinogenesis by a COX-2 inhibitor and PPAR ligands.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Bezafibrate; Body Weight; Chromans; Col | 2005 |
Comparative gastrointestinal toxicity of selective cyclooxygenase (COX-2) inhibitors.
Topics: Animals; Celecoxib; Colitis; Cyclooxygenase Inhibitors; Gastric Mucosa; Gastrointestinal Tract; Indo | 2005 |
Effects of nimesulide, a cyclooxygenase-2 selective inhibitor, on colitis induced tumors.
Topics: Administration, Oral; Analysis of Variance; Animals; Chi-Square Distribution; Chronic Disease; Colit | 2008 |
Cyclo-oxygenase-2 inhibitors ameliorate the severity of experimental colitis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Cyclooxygenase Inhibitors; Disease Models | 2000 |
The COX-2 inhibitor nimesulide suppresses superoxide and 8-hydroxy-deoxyguanosine formation, and stimulates apoptosis in mucosa during early colonic inflammation in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Colitis; C | 2000 |
The effect of alpha-melanocyte stimulating hormone on colonic inflammation in the rat.
Topics: alpha-MSH; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Colitis; Cyclo | 2000 |
Protective role of cyclooxygenase inhibitors in the adverse action of passive cigarette smoking on the initiation of experimental colitis in rats.
Topics: Animals; Blotting, Western; Colitis; Colon; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inh | 2001 |
Effects of a COX-2 preferential agent nimesulide on TNBS-induced acute inflammation in the gut.
Topics: Acute Disease; Animals; Aspirin; Colitis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygen | 2001 |