Page last updated: 2024-11-01

nimesulide and Cardiac Diseases

nimesulide has been researched along with Cardiac Diseases in 3 studies

nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.

Research Excerpts

ExcerptRelevanceReference
" We investigated the effect of nimesulide (NIM), a selective cyclooxygenase-2 (COX-2) inhibitor, on the cardiovascular alterations occurring during endotoxemia, and on prostaglandin E2 (PGE2), tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) levels in endotoxemic rats."7.73Effects of nimesulide, a selective cyclooxygenase-2 inhibitor, on cardiovascular alterations in endotoxemia. ( Azab, AN; Kaplanski, J; Kobal, S; Rubin, M, 2005)
"We hypothesized that acute pharmacological blockade of cyclooxygenase-2 (COX-2) using nimesulide (Nime) would prevent maladaptive changes in left ventricular (LV) structure and function secondary to abdominal aortic coarctation-induced pressure overload (PO)."3.78Alteration in myocardial prostaglandin D synthase expression in pressure overload-induced left ventricular remodeling in rats. ( Claudino, MA; Gardner, JD; Gole, M; Murray, DB; Nagalla, KT, 2012)
"In a term pregnancy, nimesulide administration can rapidly cause premature ductal constriction."3.74Acute premature constriction of the ductus arteriosus after maternal self-medication with nimesulide. ( De Biasio, P; Marasini, M; Prefumo, F; Venturini, PL, 2008)
" We investigated the effect of nimesulide (NIM), a selective cyclooxygenase-2 (COX-2) inhibitor, on the cardiovascular alterations occurring during endotoxemia, and on prostaglandin E2 (PGE2), tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) levels in endotoxemic rats."3.73Effects of nimesulide, a selective cyclooxygenase-2 inhibitor, on cardiovascular alterations in endotoxemia. ( Azab, AN; Kaplanski, J; Kobal, S; Rubin, M, 2005)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagalla, KT1
Gole, M1
Claudino, MA1
Gardner, JD1
Murray, DB1
Azab, AN1
Kobal, S1
Rubin, M1
Kaplanski, J1
Prefumo, F1
Marasini, M1
De Biasio, P1
Venturini, PL1

Other Studies

3 other studies available for nimesulide and Cardiac Diseases

ArticleYear
Alteration in myocardial prostaglandin D synthase expression in pressure overload-induced left ventricular remodeling in rats.
    Experimental biology and medicine (Maywood, N.J.), 2012, Volume: 237, Issue:1

    Topics: Animals; Aortic Coarctation; Collagen; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Heart; Heart D

2012
Effects of nimesulide, a selective cyclooxygenase-2 inhibitor, on cardiovascular alterations in endotoxemia.
    Cardiology, 2005, Volume: 103, Issue:2

    Topics: Animals; Blotting, Western; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors

2005
Acute premature constriction of the ductus arteriosus after maternal self-medication with nimesulide.
    Fetal diagnosis and therapy, 2008, Volume: 24, Issue:1

    Topics: Acute Disease; Adult; Constriction, Pathologic; Cyclooxygenase 2 Inhibitors; Ductus Arteriosus; Fema

2008