nimesulide has been researched along with Carcinoma, Hepatocellular in 6 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effect of nimesulide on cell apoptosis and possible mechanism in human hepatocellular carcinoma SMMC-7721 cells." | 7.78 | [Downregulation of HSP70 gene expression and apoptosis in human hepatocellular carcinoma SMMC-7721 cells induced by nimesulide in vitro]. ( Han, SS; Liu, QG; Tu, KS; Wang, J; Yao, YM; Yin, GZ, 2012) |
| "Hepatocellular carcinoma is emerging as one of the most common forms of cancer resulting in thousands of death worldwide." | 5.51 | Antineoplastic influence of nimesulide in chemically induced hepatocellular carcinoma by inhibition of DNA synthesis. ( Afzal, M; Al-Abbasi, FA; Anwar, F; Bhardwaj, DP; Kazmi, I; Khan, R; Saleem, S, 2019) |
| "To investigate the effect of nimesulide on cell apoptosis and possible mechanism in human hepatocellular carcinoma SMMC-7721 cells." | 3.78 | [Downregulation of HSP70 gene expression and apoptosis in human hepatocellular carcinoma SMMC-7721 cells induced by nimesulide in vitro]. ( Han, SS; Liu, QG; Tu, KS; Wang, J; Yao, YM; Yin, GZ, 2012) |
| "This study was designed to investigate the role of COX-2 inhibitor nimesulide in cell growth and apoptosis of the cultured human hepatocellular carcinoma HepG2 cells." | 3.74 | Combination of cyclooxygenase-2 inhibitor and doxorubicin increases the growth inhibition and apoptosis in human hepatocellular carcinoma cells. ( Jia, XY; Pan, YY; Rui, LX; Wei, W; Xu, HQ; Xu, SP; Zhang, Y, 2007) |
| "Hepatocellular carcinoma is emerging as one of the most common forms of cancer resulting in thousands of death worldwide." | 1.51 | Antineoplastic influence of nimesulide in chemically induced hepatocellular carcinoma by inhibition of DNA synthesis. ( Afzal, M; Al-Abbasi, FA; Anwar, F; Bhardwaj, DP; Kazmi, I; Khan, R; Saleem, S, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Afzal, M | 1 |
| Bhardwaj, DP | 1 |
| Khan, R | 1 |
| Kazmi, I | 1 |
| Saleem, S | 1 |
| Al-Abbasi, FA | 1 |
| Anwar, F | 1 |
| Yin, GZ | 1 |
| Tu, KS | 1 |
| Han, SS | 1 |
| Wang, J | 1 |
| Liu, QG | 1 |
| Yao, YM | 1 |
| Berson, A | 1 |
| Cazanave, S | 1 |
| Descatoire, V | 1 |
| Tinel, M | 1 |
| Grodet, A | 1 |
| Wolf, C | 1 |
| Feldmann, G | 1 |
| Pessayre, D | 1 |
| Pan, YY | 1 |
| Xu, SP | 1 |
| Jia, XY | 1 |
| Xu, HQ | 1 |
| Zhang, Y | 1 |
| Rui, LX | 1 |
| Wei, W | 1 |
| Liu, YJ | 1 |
| Ma, YF | 1 |
| Zhang, J | 1 |
| Zhao, YP | 1 |
| Bai, HL | 1 |
| Li, SL | 1 |
| Tian, G | 1 |
| Yu, JP | 1 |
| Luo, HS | 1 |
| Yu, BP | 1 |
| Yue, H | 1 |
| Li, JY | 1 |
| Mei, Q | 1 |
6 other studies available for nimesulide and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Antineoplastic influence of nimesulide in chemically induced hepatocellular carcinoma by inhibition of DNA synthesis.
Topics: Animals; Antineoplastic Agents; Antioxidants; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Surv | 2019 |
[Downregulation of HSP70 gene expression and apoptosis in human hepatocellular carcinoma SMMC-7721 cells induced by nimesulide in vitro].
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationsh | 2012 |
The anti-inflammatory drug, nimesulide (4-nitro-2-phenoxymethane-sulfoanilide), uncouples mitochondria and induces mitochondrial permeability transition in human hepatoma cells: protection by albumin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Hepatocellular; Cattle; Cell Line, Tumo | 2006 |
Combination of cyclooxygenase-2 inhibitor and doxorubicin increases the growth inhibition and apoptosis in human hepatocellular carcinoma cells.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibit | 2007 |
[Synergistic lethal effect of mDRA-6 and nimesulide on human hepatocellular cancer cell line SMMC-7721].
Topics: Antibodies, Monoclonal; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclooxygenase 2; Dr | 2008 |
Effect of nimesulide on proliferation and apoptosis of human hepatoma SMMC-7721 cells.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; | 2002 |