Page last updated: 2024-11-01

nimesulide and Cancer of Stomach

nimesulide has been researched along with Cancer of Stomach in 7 studies

nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the potential role of Nimesulide, a selective COX-2 inhibitor, in proliferation and apoptosis of gastric adenocarcinoma cells SGC7901."7.72Nimesulide inhibits proliferation via induction of apoptosis and cell cycle arrest in human gastric adenocarcinoma cell line. ( Chen, FL; Li, JY; Luo, HS; Wang, XZ; Yu, JP, 2003)
"To evaluate the potential role of Nimesulide, a selective COX-2 inhibitor, in proliferation and apoptosis of gastric adenocarcinoma cells SGC7901."3.72Nimesulide inhibits proliferation via induction of apoptosis and cell cycle arrest in human gastric adenocarcinoma cell line. ( Chen, FL; Li, JY; Luo, HS; Wang, XZ; Yu, JP, 2003)
" The current study was designed to evaluate the potential role of Nimesulide, a selective COX-2 inhibitor, on the PGE2 level, proliferation and apoptosis of gastric adenocarcinoma cell line SGC7901."3.71[Influence of selective cyclooxygenase-2 inhibitor on proliferation of human gastric cancer cells]. ( Huang, JA; Li, JY; Luo, HS; Mei, Q; Tian, G; Yu, BP; Yu, JP, 2002)
" pylori, especially after MNU administration to promote carcinogenesis and the effects of the long-term administration of rebamipide or nimesulide were evaluated."2.42Chemoprevention of Helicobacter pylori-associated gastric carcinogenesis in a mouse model: is it possible? ( Cho, SW; Hahm, KB; Han, SU; Kim, DY; Kim, JH; Kim, MW; Kim, YB; Lee, JS; Nahm, KT; Oh, TY; Song, YJ; Surh, YJ; Yoo, BM, 2003)
"In the gastric cancer cell line MKN-45 nimesulide caused a time- and dose-dependent reduction in cell numbers and significantly inhibited telomerase and Akt/PKB activity; the inhibition of telomerase activity was partly associated with the attenuation of Akt/PKB activity."1.32Cyclooxygenase-2 inhibitor nimesulide suppresses telomerase activity by blocking Akt/PKB activation in gastric cancer cell line. ( Baoping, Y; Guoyong, H; Hesheng, L; Jieping, Y; Zongxue, R, 2004)
"In vitro experiments with the human gastric cancer cell line AGS were also performed to identify mechanisms underlying cancer chemoprevention by nimesulide."1.32The selective cyclooxygenase-2 inhibitor nimesulide prevents Helicobacter pylori-associated gastric cancer development in a mouse model. ( Ahn, B; Hahm, KB; Han, SU; Jang, DD; Kang, JS; Kim, DY; Kim, YB; Nam, KT; Oh, SY; Yang, KH; Yeo, M, 2004)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (85.71)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, JQ1
Chen, FX1
Gong, XJ1
Li, HZ1
Cai, K1
Zhang, BF1
Zhang, S1
Zhang, J1
Li, JY2
Yu, JP3
Luo, HS3
Yu, BP2
Tian, G1
Mei, Q1
Huang, JA1
Hahm, KB2
Song, YJ1
Oh, TY1
Lee, JS1
Surh, YJ1
Kim, YB2
Yoo, BM1
Kim, JH1
Han, SU2
Nahm, KT1
Kim, MW1
Kim, DY2
Cho, SW1
Wang, XZ1
Chen, FL1
Baoping, Y1
Guoyong, H1
Jieping, Y1
Zongxue, R1
Hesheng, L1
Hu, GY1
Ran, ZX1
Nam, KT1
Oh, SY1
Yeo, M1
Ahn, B1
Kang, JS1
Jang, DD1
Yang, KH1

Reviews

1 review available for nimesulide and Cancer of Stomach

ArticleYear
Chemoprevention of Helicobacter pylori-associated gastric carcinogenesis in a mouse model: is it possible?
    Journal of biochemistry and molecular biology, 2003, Jan-31, Volume: 36, Issue:1

    Topics: Alanine; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cyto

2003

Other Studies

6 other studies available for nimesulide and Cancer of Stomach

ArticleYear
[Mechanistic study of nimesulide on enhancing gammadeltaT cell-mediated killing of gastric cancer cells].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2010, Volume: 26, Issue:3

    Topics: Cell Line, Tumor; Cells, Cultured; Cytotoxicity, Immunologic; Granzymes; Humans; Interferon-gamma; P

2010
[Influence of selective cyclooxygenase-2 inhibitor on proliferation of human gastric cancer cells].
    Ai zheng = Aizheng = Chinese journal of cancer, 2002, Volume: 21, Issue:6

    Topics: Adenocarcinoma; Apoptosis; Cell Cycle; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors;

2002
Nimesulide inhibits proliferation via induction of apoptosis and cell cycle arrest in human gastric adenocarcinoma cell line.
    World journal of gastroenterology, 2003, Volume: 9, Issue:5

    Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Cycle; Cell Cycle Proteins;

2003
Cyclooxygenase-2 inhibitor nimesulide suppresses telomerase activity by blocking Akt/PKB activation in gastric cancer cell line.
    Digestive diseases and sciences, 2004, Volume: 49, Issue:6

    Topics: Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhib

2004
[Nimesulide, a selective cyclooxygenase-2 inhibitor inhibits telomerase activity by blocking activation of PKB in gastric cancer cell line].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2004, Volume: 26, Issue:4

    Topics: Adenocarcinoma; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase Inhibitors; Dose-Response Relat

2004
The selective cyclooxygenase-2 inhibitor nimesulide prevents Helicobacter pylori-associated gastric cancer development in a mouse model.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Dec-01, Volume: 10, Issue:23

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cyclooxygenase 2; Cyclooxygenase

2004