nimesulide has been researched along with Cancer of Pancreas in 6 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nimesulide is a nonsteroidal anti-inflammatory drug and a COX-2 inhibitor with antitumor and antiproliferative activities that induces apoptosis in oral, esophagus, breast, and pancreatic cancer cells." | 1.91 | Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering †. ( Been, M; Huber, E; Liao, EE; Lo, CH; Sachs, JN; Thomas, DD; Vunnam, N; Young, MC, 2023) |
| "In vitro findings were validated in a pancreatic cancer animal model." | 1.33 | Growth stimulation of COX-2-negative pancreatic cancer by a selective COX-2 inhibitor. ( Boros, LG; Eibl, G; Hines, OJ; Liu, J; Okada, Y; Reber, HA; Takata, Y, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Vunnam, N | 1 |
| Young, MC | 1 |
| Liao, EE | 1 |
| Lo, CH | 1 |
| Huber, E | 1 |
| Been, M | 1 |
| Thomas, DD | 1 |
| Sachs, JN | 1 |
| Eibl, G | 4 |
| Reber, HA | 4 |
| Wente, MN | 1 |
| Hines, OJ | 4 |
| Furukawa, F | 1 |
| Nishikawa, A | 1 |
| Lee, IS | 1 |
| Kanki, K | 1 |
| Umemura, T | 1 |
| Okazaki, K | 1 |
| Kawamori, T | 1 |
| Wakabayashi, K | 1 |
| Hirose, M | 1 |
| Bruemmer, D | 1 |
| Okada, Y | 2 |
| Duffy, JP | 1 |
| Law, RE | 1 |
| Takata, Y | 1 |
| Boros, LG | 1 |
| Liu, J | 1 |
| Funahashi, H | 1 |
| Satake, M | 1 |
| Dawson, D | 1 |
| Huynh, NA | 1 |
6 other studies available for nimesulide and Cancer of Pancreas
| Article | Year |
|---|---|
Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering †.
Topics: Apoptosis; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; Humans; Pancreatic Neoplasms; Receptors, T | 2023 |
Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering †.
Topics: Apoptosis; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; Humans; Pancreatic Neoplasms; Receptors, T | 2023 |
Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering †.
Topics: Apoptosis; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; Humans; Pancreatic Neoplasms; Receptors, T | 2023 |
Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering †.
Topics: Apoptosis; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; Humans; Pancreatic Neoplasms; Receptors, T | 2023 |
The selective cyclooxygenase-2 inhibitor nimesulide induces apoptosis in pancreatic cancer cells independent of COX-2.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Cell Division; Cell Survival; Cyclooxygenase | 2003 |
A cyclooxygenase-2 inhibitor, nimesulide, inhibits postinitiation phase of N-nitrosobis(2-oxopropyl)amine-induced pancreatic carcinogenesis in hamsters.
Topics: Adenocarcinoma; Animals; Cell Transformation, Neoplastic; Cricetinae; Cyclooxygenase 2; Cyclooxygena | 2003 |
PGE(2) is generated by specific COX-2 activity and increases VEGF production in COX-2-expressing human pancreatic cancer cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Arachidonic Acid; Blotting, Western; Cell Movement; Cells, C | 2003 |
Growth stimulation of COX-2-negative pancreatic cancer by a selective COX-2 inhibitor.
Topics: Animals; Cell Growth Processes; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyc | 2005 |
Delayed progression of pancreatic intraepithelial neoplasia in a conditional Kras(G12D) mouse model by a selective cyclooxygenase-2 inhibitor.
Topics: Animals; Carcinoma, Pancreatic Ductal; Cyclooxygenase 2 Inhibitors; Dinoprostone; Disease Models, An | 2007 |