nimesulide has been researched along with Asthma in 13 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The herein described challenge with alternative drugs, meloxicam and nimesulide, is a safe tool for the management of NSAIDs-intolerant patients." | 2.71 | Nimesulide and meloxicam are a safe alternative drugs for patients intolerant to nonsteroidal anti-inflammatory drugs. ( Bonadonna, P; Canonica, GW; Crivellaro, M; Dama, A; Passalacqua, G; Schiappoli, M; Senna, GE, 2003) |
| " One hundred twenty-seven subjects with history of adverse reaction to ASA/NSAIDs received oral challenges with nimesulide, 61 subjects were challenged with meloxicam, 51 subjects were challenged with rofecoxib, and 37 subjects were challenged with all three drugs." | 2.71 | Safety of selective COX-2 inhibitors in aspirin/nonsteroidal anti-inflammatory drug-intolerant patients: comparison of nimesulide, meloxicam, and rofecoxib. ( Bavbek, S; Celik, G; Misirligil, Z; Mungan, D; Ozer, F, 2004) |
| "One component of airway remodeling involves fibroblast accumulation and activation, resulting in deposition of collagen I around small bronchi." | 1.37 | Airway remodeling in murine asthma correlates with a defect in PGE2 synthesis by lung fibroblasts. ( Jancar, S; Peters-Golden, M; Stumm, CL; Wettlaufer, SH, 2011) |
| "Nimesulide was tolerated by 115/122 (94." | 1.30 | Long-term tolerability of nimesulide and acetaminophen in nonsteroidal antiinflammatory drug-intolerant patients. ( D'Ambrosio, FP; Di Fonso, M; Giuffreda, F; Papa, G; Quaratino, D; Romano, A; Venuti, A, 1997) |
| "Nimesulide is a nonsteroidal anti-inflammatory drug, supposed to act by inhibition of phosphodiesterase type IV." | 1.29 | The effect of salmeterol and nimesulide on chemotaxis and synthesis of PAF and LTC4 by human eosinophils. ( Knol, EF; Mul, FP; Roos, D; Tool, AT; Verhoeven, AJ, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (61.54) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stumm, CL | 1 |
| Wettlaufer, SH | 1 |
| Jancar, S | 1 |
| Peters-Golden, M | 1 |
| Gray, PA | 1 |
| Warner, TD | 1 |
| Vojnovic, I | 1 |
| Del Soldato, P | 1 |
| Parikh, A | 1 |
| Scadding, GK | 1 |
| Mitchell, JA | 1 |
| Senna, GE | 2 |
| Passalacqua, G | 2 |
| Dama, A | 1 |
| Crivellaro, M | 1 |
| Schiappoli, M | 1 |
| Bonadonna, P | 1 |
| Canonica, GW | 1 |
| Bavbek, S | 2 |
| Celik, G | 2 |
| Ozer, F | 1 |
| Mungan, D | 2 |
| Misirligil, Z | 2 |
| Bianco, S | 1 |
| Robuschi, M | 1 |
| Petrigni, G | 1 |
| Scuri, M | 1 |
| Pieroni, MG | 1 |
| Refini, RM | 1 |
| Vaghi, A | 1 |
| Sestini, PS | 1 |
| Brusasco, V | 2 |
| Crimi, E | 2 |
| Scaricabarozzi, I | 2 |
| Andri, G | 1 |
| Dama, AR | 1 |
| Albano, M | 1 |
| Fregonese, L | 1 |
| Andri, L | 1 |
| Tool, AT | 1 |
| Mul, FP | 1 |
| Knol, EF | 1 |
| Verhoeven, AJ | 1 |
| Roos, D | 1 |
| Quaratino, D | 1 |
| Romano, A | 1 |
| Papa, G | 1 |
| Di Fonso, M | 1 |
| Giuffreda, F | 1 |
| D'Ambrosio, FP | 1 |
| Venuti, A | 1 |
| Pastorello, EA | 1 |
| Zara, C | 1 |
| Riario-Sforza, GG | 1 |
| Pravettoni, V | 1 |
| Incorvaia, C | 1 |
| Ediger, D | 1 |
| Demirel, YS | 1 |
| Mangalvedhekar, SS | 1 |
| Gogtay, NJ | 1 |
| Phadke, AV | 1 |
| Gore, S | 1 |
| Shah, JM | 1 |
| Shah, SM | 1 |
| Kshirsagar, NA | 1 |
| De Lucia, F | 1 |
| Bonavia, M | 1 |
2 reviews available for nimesulide and Asthma
| Article | Year |
|---|---|
Efficacy and tolerability of nimesulide in asthmatic patients intolerant to aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Clinical Trials as Topic; Contraindication | 1993 |
Nimesulide in the treatment of patients intolerant of aspirin and other NSAIDs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Humans; Rhinitis; Sulfonamides | 1996 |
4 trials available for nimesulide and Asthma
| Article | Year |
|---|---|
Nimesulide and meloxicam are a safe alternative drugs for patients intolerant to nonsteroidal anti-inflammatory drugs.
Topics: Adolescent; Adult; Aged; Anaphylaxis; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Asthma; D | 2003 |
Safety of selective COX-2 inhibitors in aspirin/nonsteroidal anti-inflammatory drug-intolerant patients: comparison of nimesulide, meloxicam, and rofecoxib.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase In | 2004 |
The use of nimesulide in patients with acetylsalicylic acid and nonsteroidal anti-inflammatory drug intolerance.
Topics: Administration, Oral; Adult; Aged; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ast | 1999 |
Antiinflammatory-antioxidant treatment with a methane sulfonanilide in allergen-induced asthma.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Asthma; Bronchoconstrictio | 1991 |
7 other studies available for nimesulide and Asthma
| Article | Year |
|---|---|
Airway remodeling in murine asthma correlates with a defect in PGE2 synthesis by lung fibroblasts.
Topics: Airway Remodeling; Allergens; Animals; Asthma; Bronchi; Cell Proliferation; Chronic Disease; Collage | 2011 |
Effects of non-steroidal anti-inflammatory drugs on cyclo-oxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Benzene Derivatives; Calcimycin; Cyclooxyg | 2002 |
Nimesulide does not interfere with airway responsiveness in allergic asthma.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchi; Double-Blind Method; Dust; Humans | 1993 |
The effect of salmeterol and nimesulide on chemotaxis and synthesis of PAF and LTC4 by human eosinophils.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Chemo | 1996 |
Long-term tolerability of nimesulide and acetaminophen in nonsteroidal antiinflammatory drug-intolerant patients.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Angioedema; Ant | 1997 |
Atopy and intolerance of antimicrobial drugs increase the risk of reactions to acetaminophen and nimesulide in patients allergic to nonsteroidal anti-inflammatory drugs.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Allergens; Anti-Inflammatory Agents, Non- | 1998 |
Adverse drug reactions postal survey-bronchial asthma and angioedema with nimesulide.
Topics: Adverse Drug Reaction Reporting Systems; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Asthma | 2000 |