Page last updated: 2024-11-01

nimesulide and Arthritis

nimesulide has been researched along with Arthritis in 7 studies

nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.

Arthritis: Acute or chronic inflammation of JOINTS.

Research Excerpts

ExcerptRelevanceReference
" Nimesulide, a selective inhibitor of COX-2, has been shown to relieve pain rapidly in arthritis."9.10Inhibition of PGE2 production by nimesulide compared with diclofenac in the acutely inflamed joint of patients with arthritis. ( Belton, O; Bresnihan, B; Duffy, T; FitzGerald, D; FitzGerald, O, 2003)
" Nimesulide, a selective inhibitor of COX-2, has been shown to relieve pain rapidly in arthritis."5.10Inhibition of PGE2 production by nimesulide compared with diclofenac in the acutely inflamed joint of patients with arthritis. ( Belton, O; Bresnihan, B; Duffy, T; FitzGerald, D; FitzGerald, O, 2003)
"The present experiment was designed to determine a dosage regimen (dose, interval of administration) in the dog for nimesulide, a nonsteroidal anti-inflammatory drug with in vitro selectivity for the inhibition of cyclo-oxygenase 2 (Cox-2), using a pharmacokinetic/pharmacodynamic (PK/PD) approach."2.70A pharmacokinetic/pharmacodynamic approach vs. a dose titration for the determination of a dosage regimen: the case of nimesulide, a Cox-2 selective nonsteroidal anti-inflammatory drug in the dog. ( Cester, CC; Haak, T; Laroute, V; Toutain, PL, 2001)
"Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) administered orally or rectally twice daily for a variety of inflammatory and pain states."2.39Nimesulide. An update of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy. ( Brogden, RN; Davis, R, 1994)
"Nimesulide may cause liver damage."1.30Nimesulide-induced hepatitis and acute liver failure. ( Bar-Meir, S; Brickman, CM; Bruck, R; Farfel, Z; Hassin, D; Mouallem, M; Tanay, A; Weiss, P, 1999)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duffy, T1
Belton, O1
Bresnihan, B1
FitzGerald, O1
FitzGerald, D1
Barskova, VG1
Eliseev, MS1
Kudaeva, FM1
Weissenbach, R1
Davis, R1
Brogden, RN1
Weiss, P1
Mouallem, M1
Bruck, R1
Hassin, D1
Tanay, A1
Brickman, CM1
Farfel, Z1
Bar-Meir, S1
Toutain, PL1
Cester, CC1
Haak, T1
Laroute, V1
Nante, G1
Dal PrĂ , ML1
Mosca, M1
De Candia, O1

Reviews

2 reviews available for nimesulide and Arthritis

ArticleYear
[Nimesulide].
    Terapevticheskii arkhiv, 2007, Volume: 79, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthritis; Calcium Channel Blockers; Humans; Su

2007
Nimesulide. An update of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.
    Drugs, 1994, Volume: 48, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Humans; Sulfonamides

1994

Trials

2 trials available for nimesulide and Arthritis

ArticleYear
Inhibition of PGE2 production by nimesulide compared with diclofenac in the acutely inflamed joint of patients with arthritis.
    Drugs, 2003, Volume: 63 Suppl 1

    Topics: Acute Disease; Administration, Oral; Arthralgia; Arthritis; Cyclooxygenase 1; Cyclooxygenase 2; Dicl

2003
A pharmacokinetic/pharmacodynamic approach vs. a dose titration for the determination of a dosage regimen: the case of nimesulide, a Cox-2 selective nonsteroidal anti-inflammatory drug in the dog.
    Journal of veterinary pharmacology and therapeutics, 2001, Volume: 24, Issue:1

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cross-Over Studie

2001

Other Studies

3 other studies available for nimesulide and Arthritis

ArticleYear
Clinical trial with Nimesulide, a new non-steroid anti-inflammatory agent, in rheumatic pathology.
    The Journal of international medical research, 1981, Volume: 9, Issue:5

    Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis; Female; Humans; Male; Middle Aged; Neuralgia; Sulf

1981
Nimesulide-induced hepatitis and acute liver failure.
    The Israel Medical Association journal : IMAJ, 1999, Volume: 1, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Chemical and Drug Induc

1999
[Tolerability of nimesulide in the aged].
    La Clinica terapeutica, 1988, Feb-29, Volume: 124, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Drug Evalu

1988