nimesulide has been researched along with Arthritis, Rheumatoid in 9 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nimesulide is a COX-2 inhibitor used for symptomatic relief of rheumatoid arthritis." | 3.80 | Nimesulide improves the symptomatic and disease modifying effects of leflunomide in collagen induced arthritis. ( Abdel-Naim, AB; Al-Abbasi, FA; Al-Abd, AM; El-Eraky, WI; Khalifa, AE; Nagy, AA; Nofal, SM; Williams, RO, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kopylov, AT | 1 |
| Novikov, AA | 1 |
| Kaysheva, AL | 1 |
| Vykhodets, IT | 1 |
| Karateev, DE | 1 |
| Zgoda, VG | 1 |
| Lisitsa, AV | 1 |
| Al-Abd, AM | 1 |
| Al-Abbasi, FA | 1 |
| Nofal, SM | 1 |
| Khalifa, AE | 1 |
| Williams, RO | 1 |
| El-Eraky, WI | 1 |
| Nagy, AA | 1 |
| Abdel-Naim, AB | 1 |
| Sizova, LV | 1 |
| Bagirova, GG | 1 |
| Chernysheva, TV | 1 |
| Balabanova, RM | 1 |
| Belov, BS | 1 |
| Chichasova, NV | 1 |
| Oliunin, IuA | 1 |
| Badokin, VV | 1 |
| Pchelintseva, AO | 1 |
| Fedina, TP | 1 |
| Gukasian, DA | 1 |
| Lopatina, NE | 1 |
| Korshunov, NI | 1 |
| Baranova, EIa | 1 |
| Ilivanova, EP | 1 |
| Trifonova, SE | 1 |
| Matsievskaia, GK | 1 |
| Bianchi, M | 1 |
| Broggini, M | 1 |
| Shi, W | 1 |
| Wang, YM | 1 |
| Cheng, NN | 1 |
| Chen, BY | 1 |
| Li, D | 1 |
| Di Battista, JA | 2 |
| Fahmi, H | 2 |
| He, Y | 2 |
| Zhang, M | 2 |
| Martel-Pelletier, J | 2 |
| Pelletier, JP | 2 |
| Swingle, KF | 1 |
| Moore, GG | 1 |
| Grant, TJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "Evaluation of Pharmacokinetic Parameters of Diprospan"[NCT03119454] | 40 participants (Actual) | Observational [Patient Registry] | 2016-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for nimesulide and Arthritis, Rheumatoid
| Article | Year |
|---|---|
[Meta-analysis on the effect and adverse reaction on patients with osteoarthritis and rheumatoid arthritis treated with non-steroidal anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; China; Diclofenac; Humans | 2003 |
3 trials available for nimesulide and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Quantitative assessment of betamethasone dual-acting formulation in urine of patients with rheumatoid arthritis and ankylosing spondylitis after single-dose intramuscular administration and its application to long-term pharmacokinetic study.
Topics: Adult; Arthritis, Rheumatoid; Betamethasone; Diclofenac; Drug Combinations; Ethanol; Female; Glucoco | 2018 |
[Comparative analysis of effectiveness and safety of diclofenac and nimesulide in patients with early rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Fema | 2009 |
Anti-hyperalgesic effects of nimesulide: studies in rats and humans.
Topics: Aged; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; | 2002 |
5 other studies available for nimesulide and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Nimesulide improves the symptomatic and disease modifying effects of leflunomide in collagen induced arthritis.
Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Drug Synergism; Drug | 2014 |
[Nimesil effectiveness in rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase In | 2002 |
Differential regulation of interleukin-1 beta-induced cyclooxygenase-2 gene expression by nimesulide in human synovial fibroblasts.
Topics: Arthritis, Rheumatoid; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenas | 2001 |
Nimesulide reduces interleukin-1beta-induced cyclooxygenase-2 gene expression in human synovial fibroblasts.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclooxygenase 2; Fibroblasts; Gene | 2001 |
4-nitro-2-phenoxymethanesulfonanilide (R-805): a chemically novel anti-inflammatory agent.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Edema; Erythema; Lethal Dose 50; Male; Rat | 1976 |