nimesulide has been researched along with Arteriosclerosis in 3 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Deletion of the PGI2 receptor (IP) or suppression of PGI2 with the selective COX-2 inhibitor, nimesulide, both augment intimal hyperplasia while preserving luminal geometry in mouse models of transplant arteriosclerosis or flow-induced vascular remodeling." | 3.73 | COX-2-derived prostacyclin modulates vascular remodeling. ( Austin, S; Brinster, D; Cheng, Y; Coffman, TM; FitzGerald, GA; Fries, S; Rudic, RD; Song, WL, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rudic, RD | 1 |
| Brinster, D | 1 |
| Cheng, Y | 1 |
| Fries, S | 1 |
| Song, WL | 1 |
| Austin, S | 1 |
| Coffman, TM | 1 |
| FitzGerald, GA | 1 |
| Stanford, SJ | 1 |
| Pepper, JR | 1 |
| Mitchell, JA | 1 |
| Belton, O | 1 |
| Byrne, D | 1 |
| Kearney, D | 1 |
| Leahy, A | 1 |
| Fitzgerald, DJ | 1 |
1 trial available for nimesulide and Arteriosclerosis
| Article | Year |
|---|---|
Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis | 2000 |
2 other studies available for nimesulide and Arteriosclerosis
| Article | Year |
|---|---|
COX-2-derived prostacyclin modulates vascular remodeling.
Topics: Animals; Arteries; Arteriosclerosis; Blood Vessels; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; C | 2005 |
Cyclooxygenase-2 regulates granulocyte-macrophage colony-stimulating factor, but not interleukin-8, production by human vascular cells: role of cAMP.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arteriosclerosis; Aspirin; Bucladesi | 2000 |