Page last updated: 2024-11-01

nimesulide and Aortic Coarctation

nimesulide has been researched along with Aortic Coarctation in 1 studies

nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.

Aortic Coarctation: A birth defect characterized by the narrowing of the AORTA that can be of varying degree and at any point from the transverse arch to the iliac bifurcation. Aortic coarctation causes arterial HYPERTENSION before the point of narrowing and arterial HYPOTENSION beyond the narrowed portion.

Research Excerpts

ExcerptRelevanceReference
"We hypothesized that acute pharmacological blockade of cyclooxygenase-2 (COX-2) using nimesulide (Nime) would prevent maladaptive changes in left ventricular (LV) structure and function secondary to abdominal aortic coarctation-induced pressure overload (PO)."3.78Alteration in myocardial prostaglandin D synthase expression in pressure overload-induced left ventricular remodeling in rats. ( Claudino, MA; Gardner, JD; Gole, M; Murray, DB; Nagalla, KT, 2012)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagalla, KT1
Gole, M1
Claudino, MA1
Gardner, JD1
Murray, DB1

Other Studies

1 other study available for nimesulide and Aortic Coarctation

ArticleYear
Alteration in myocardial prostaglandin D synthase expression in pressure overload-induced left ventricular remodeling in rats.
    Experimental biology and medicine (Maywood, N.J.), 2012, Volume: 237, Issue:1

    Topics: Animals; Aortic Coarctation; Collagen; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Heart; Heart D

2012