nimesulide has been researched along with American Trypanosomiasis in 2 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chagas disease is a neglected illness caused by Trypanosoma cruzi and its treatment is done only with two drugs, nifurtimox and benznidazole." | 5.62 | Drug repurposing for Chagas disease: In vitro assessment of nimesulide against Trypanosoma cruzi and insights on its mechanisms of action. ( Côrte-Real, S; Decote-Ricardo, D; Freire de Lima, ME; Freire-de-Lima, CG; Trindade, JDS, 2021) |
| "Chagas disease is a neglected illness caused by Trypanosoma cruzi and its treatment is done only with two drugs, nifurtimox and benznidazole." | 1.62 | Drug repurposing for Chagas disease: In vitro assessment of nimesulide against Trypanosoma cruzi and insights on its mechanisms of action. ( Côrte-Real, S; Decote-Ricardo, D; Freire de Lima, ME; Freire-de-Lima, CG; Trindade, JDS, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Trindade, JDS | 1 |
| Freire-de-Lima, CG | 1 |
| Côrte-Real, S | 1 |
| Decote-Ricardo, D | 1 |
| Freire de Lima, ME | 1 |
| Escalante, RD | 1 |
| de Oliveira, EC | 1 |
| Cunha, FQ | 1 |
| Vespúcio, MV | 1 |
| Ribeiro-Silva, A | 1 |
| Aprilli, F | 1 |
| Garcia, SB | 1 |
2 other studies available for nimesulide and American Trypanosomiasis
| Article | Year |
|---|---|
Drug repurposing for Chagas disease: In vitro assessment of nimesulide against Trypanosoma cruzi and insights on its mechanisms of action.
Topics: Animals; Cell Death; Cell Survival; Chagas Disease; Drug Repositioning; Life Cycle Stages; Mice, Inb | 2021 |
Trypanosoma cruzi infection and/or administration of the nonsteroidal anti-inflammatory nimesulide increase the number of colonic crypts overexpressing metallothioneins in rat colon carcinogenesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinogens; Chagas Disease; Colorectal Neoplasms; | 2006 |