nimesulide has been researched along with Alcohol Abuse in 2 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nimesulide treatment (10 mg/kg) prevented the ethanol withdrawal-induced alterations in the levels of TNF-α, IL-1β, and IL-6 in the hippocampus, prefrontal cortex, and striatum." | 1.72 | Attenuation of the levels of pro-inflammatory cytokines prevents depressive-like behavior during ethanol withdrawal in mice. ( Buss, ZS; Doneda, DL; Fernandes, IL; Fraga-Junior, EB; Lima, E; Rios-Santos, F; Rohden, CAH; Vandresen-Filho, S; Ynoue, HN, 2022) |
| " Mice were made physically dependent on alcohol by the chronic administration of ethanol (2 g/kg of 10% v/v), intragastrically, twice on day 1 and then once-daily on successive days for a total of 7 days." | 1.33 | Protective effect of cyclooxygenase-2 (COX-2) inhibitors but not non-selective cyclooxygenase (COX)-inhibitors on ethanol withdrawal-induced behavioural changes. ( Dhir, A; Kulkarni, SK; Naidu, PS, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fraga-Junior, EB | 1 |
| Fernandes, IL | 1 |
| Rohden, CAH | 1 |
| Doneda, DL | 1 |
| Ynoue, HN | 1 |
| Rios-Santos, F | 1 |
| Lima, E | 1 |
| Buss, ZS | 1 |
| Vandresen-Filho, S | 1 |
| Dhir, A | 1 |
| Naidu, PS | 1 |
| Kulkarni, SK | 1 |
2 other studies available for nimesulide and Alcohol Abuse
| Article | Year |
|---|---|
Attenuation of the levels of pro-inflammatory cytokines prevents depressive-like behavior during ethanol withdrawal in mice.
Topics: Alcoholism; Animals; Behavior, Animal; Cytokines; Depression; Ethanol; Hippocampus; Interleukin-6; L | 2022 |
Protective effect of cyclooxygenase-2 (COX-2) inhibitors but not non-selective cyclooxygenase (COX)-inhibitors on ethanol withdrawal-induced behavioural changes.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Animals; Behavior, Animal; Brain; Cyclooxygenase 2 Inhibito | 2005 |