nimesulide has been researched along with Adverse Drug Event in 11 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | 1.37 | FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) |
| "Nimesulide is an NSAID, with cox-2 preference, which has been reported to cause death from hepatic failure." | 1.34 | Nimesulide-induced hepatotoxicity and fatal hepatic failure. ( Chow, WC; Lai, SH; Ong, WM; Tan, HH, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M | 1 |
| Vijay, V | 1 |
| Shi, Q | 2 |
| Liu, Z | 2 |
| Fang, H | 2 |
| Tong, W | 2 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Umar, M | 1 |
| Bin Naeem, MA | 1 |
| Rashid, K | 1 |
| Sinha, K | 1 |
| Sil, PC | 1 |
| Kshirsagar, NA | 1 |
| Bachhav, SS | 1 |
| Bissoli, F | 1 |
| Stiefelhagen, P | 1 |
| Tan, HH | 1 |
| Ong, WM | 1 |
| Lai, SH | 1 |
| Chow, WC | 1 |
| Flint, SR | 1 |
| O'Sullivan, C | 1 |
| Arthur, N | 1 |
1 review available for nimesulide and Adverse Drug Event
| Article | Year |
|---|---|
An update on oxidative stress-mediated organ pathophysiology.
Topics: Acetaminophen; Animals; Antioxidants; Arsenic; Cadmium; Carbon Tetrachloride; Cisplatin; Diabetes Me | 2013 |
10 other studies available for nimesulide and Adverse Drug Event
| Article | Year |
|---|---|
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des | 2011 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Rampant Use Of Nimesulide In Pakistan, A Drug Associated With Hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Humans; Pak | 2023 |
Nimesulide controversy: a comparison of EU and Indian scenario.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug and Narcotic Control; Drug-Related Side Effects and Ad | 2013 |
Comment on: severe hemolytic anemia and fatal hepatic failure associated with nimesulide.
Topics: Anemia, Hemolytic; Anti-Inflammatory Agents, Non-Steroidal; Causality; Drug-Related Side Effects and | 2009 |
["Doing something good" for the body? Definitely not! Liver damage caused by food supplements].
Topics: Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug | 2010 |
Nimesulide-induced hepatotoxicity and fatal hepatic failure.
Topics: Aged; Cyclooxygenase 2 Inhibitors; Drug-Related Side Effects and Adverse Reactions; Fatal Outcome; F | 2007 |
An update of adverse drug reactions of relevance to general dental practice.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Amoxicillin-Potassium Clavulanate Combination; Anest | 2000 |