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nimesulide and Adenocarcinoma, Basal Cell

nimesulide has been researched along with Adenocarcinoma, Basal Cell in 10 studies

nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the potential role of Nimesulide, a selective COX-2 inhibitor, in proliferation and apoptosis of gastric adenocarcinoma cells SGC7901."7.72Nimesulide inhibits proliferation via induction of apoptosis and cell cycle arrest in human gastric adenocarcinoma cell line. ( Chen, FL; Li, JY; Luo, HS; Wang, XZ; Yu, JP, 2003)
"The aim of our study was to characterize the effects of two COX-2 selective inhibitors, NS-398 and nimesulide, on colorectal cancer cell proliferation, and to describe the molecular mechanisms involved."7.72Molecular mechanisms involved in the antiproliferative effect of two COX-2 inhibitors, nimesulide and NS-398, on colorectal cancer cell lines. ( Blottière, HM; Bonnet, C; Bouancheau, D; Broquet, A; Buecher, B; Denis, MG; Galmiche, JP; Heymann, MF; Jany, A, 2003)
"The effects of the cyclooxygenase (COX)-2 inhibitor nimesulide on bombesin-enhanced peritoneal metastasis of azoxymethane (AOM)-induced intestinal adenocarcinomas were investigated in male Wistar rats."7.72Suppression by nimesulide of bombesin-enhanced peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar rats. ( Akedo, H; Baba, M; Higashino, K; Iishi, H; Mukai, M; Tatsuta, M; Yano, H, 2003)
"In the control group, esophagitis, Barrett's esophagus (BE) and adenocarcinoma (EAC) were observed, and the frequency of these conditions increased with time."5.34[Cyclooxygenase (COX)-2 expression in a rat duodenoesophageal reflux model and chemoprevention of adenocarcinoma by the selective COX-2 inhibitor nimesulide]. ( Fujimura, T; Fushida, S; Kinami, S; Miyashita, T; Ninomiya, I; Ohta, T; Oyama, K, 2007)
"To evaluate the potential role of Nimesulide, a selective COX-2 inhibitor, in proliferation and apoptosis of gastric adenocarcinoma cells SGC7901."3.72Nimesulide inhibits proliferation via induction of apoptosis and cell cycle arrest in human gastric adenocarcinoma cell line. ( Chen, FL; Li, JY; Luo, HS; Wang, XZ; Yu, JP, 2003)
"The aim of our study was to characterize the effects of two COX-2 selective inhibitors, NS-398 and nimesulide, on colorectal cancer cell proliferation, and to describe the molecular mechanisms involved."3.72Molecular mechanisms involved in the antiproliferative effect of two COX-2 inhibitors, nimesulide and NS-398, on colorectal cancer cell lines. ( Blottière, HM; Bonnet, C; Bouancheau, D; Broquet, A; Buecher, B; Denis, MG; Galmiche, JP; Heymann, MF; Jany, A, 2003)
"The effects of the cyclooxygenase (COX)-2 inhibitor nimesulide on bombesin-enhanced peritoneal metastasis of azoxymethane (AOM)-induced intestinal adenocarcinomas were investigated in male Wistar rats."3.72Suppression by nimesulide of bombesin-enhanced peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar rats. ( Akedo, H; Baba, M; Higashino, K; Iishi, H; Mukai, M; Tatsuta, M; Yano, H, 2003)
" The current study was designed to evaluate the potential role of Nimesulide, a selective COX-2 inhibitor, on the PGE2 level, proliferation and apoptosis of gastric adenocarcinoma cell line SGC7901."3.71[Influence of selective cyclooxygenase-2 inhibitor on proliferation of human gastric cancer cells]. ( Huang, JA; Li, JY; Luo, HS; Mei, Q; Tian, G; Yu, BP; Yu, JP, 2002)
"To investigate the effects of 5-aminosalicylic acid (5-ASA) in combination with nimesulide on the proliferation of HT-29 colon carcinoma cells and its potential mechanisms."1.345-aminosalicylic acid in combination with nimesulide inhibits proliferation of colon carcinoma cells in vitro. ( Fang, HM; Ma, WJ; Mei, Q; Xu, JM, 2007)
"In the control group, esophagitis, Barrett's esophagus (BE) and adenocarcinoma (EAC) were observed, and the frequency of these conditions increased with time."1.34[Cyclooxygenase (COX)-2 expression in a rat duodenoesophageal reflux model and chemoprevention of adenocarcinoma by the selective COX-2 inhibitor nimesulide]. ( Fujimura, T; Fushida, S; Kinami, S; Miyashita, T; Ninomiya, I; Ohta, T; Oyama, K, 2007)
"The incidence of oesophageal cancer (OC) has risen in recent decades, with survival rates remaining poor despite surgical treatment and adjuvant chemotherapy."1.34Cyclooxygenase-2 inhibitors demonstrate anti-proliferative effects in oesophageal cancer cells by prostaglandin E(2)-independent mechanisms. ( Deasy, BM; McKenna, SL; O'Donovan, TR; O'Sullivan, GC; O'Sullivan-Coyne, G, 2007)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, JY2
Yu, JP3
Luo, HS3
Yu, BP2
Tian, G1
Mei, Q2
Huang, JA1
Furukawa, F1
Nishikawa, A1
Lee, IS1
Kanki, K1
Umemura, T1
Okazaki, K1
Kawamori, T1
Wakabayashi, K1
Hirose, M1
Wang, XZ1
Chen, FL1
Buecher, B1
Broquet, A1
Bouancheau, D1
Heymann, MF1
Jany, A1
Denis, MG1
Bonnet, C1
Galmiche, JP1
Blottière, HM1
Iishi, H1
Tatsuta, M1
Baba, M1
Yano, H1
Higashino, K1
Mukai, M1
Akedo, H1
Hu, GY1
Ran, ZX1
Zeng, Y1
Yokohira, M1
Saoo, K1
Takeuchi, H1
Chen, Y1
Yamakawa, K1
Matsuda, Y1
Kakehi, Y1
Imaida, K1
Fang, HM1
Xu, JM1
Ma, WJ1
Oyama, K1
Fujimura, T1
Ninomiya, I1
Miyashita, T1
Kinami, S1
Fushida, S1
Ohta, T1
Deasy, BM1
O'Sullivan-Coyne, G1
O'Donovan, TR1
McKenna, SL1
O'Sullivan, GC1

Other Studies

10 other studies available for nimesulide and Adenocarcinoma, Basal Cell

ArticleYear
[Influence of selective cyclooxygenase-2 inhibitor on proliferation of human gastric cancer cells].
    Ai zheng = Aizheng = Chinese journal of cancer, 2002, Volume: 21, Issue:6

    Topics: Adenocarcinoma; Apoptosis; Cell Cycle; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors;

2002
A cyclooxygenase-2 inhibitor, nimesulide, inhibits postinitiation phase of N-nitrosobis(2-oxopropyl)amine-induced pancreatic carcinogenesis in hamsters.
    International journal of cancer, 2003, Apr-10, Volume: 104, Issue:3

    Topics: Adenocarcinoma; Animals; Cell Transformation, Neoplastic; Cricetinae; Cyclooxygenase 2; Cyclooxygena

2003
Nimesulide inhibits proliferation via induction of apoptosis and cell cycle arrest in human gastric adenocarcinoma cell line.
    World journal of gastroenterology, 2003, Volume: 9, Issue:5

    Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Cycle; Cell Cycle Proteins;

2003
Molecular mechanisms involved in the antiproliferative effect of two COX-2 inhibitors, nimesulide and NS-398, on colorectal cancer cell lines.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2003, Volume: 35, Issue:8

    Topics: Adenocarcinoma; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Division; Colorectal Neoplas

2003
Suppression by nimesulide of bombesin-enhanced peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar rats.
    Clinical & experimental metastasis, 2003, Volume: 20, Issue:6

    Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Bombesin; Carcinogen

2003
[Nimesulide, a selective cyclooxygenase-2 inhibitor inhibits telomerase activity by blocking activation of PKB in gastric cancer cell line].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2004, Volume: 26, Issue:4

    Topics: Adenocarcinoma; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase Inhibitors; Dose-Response Relat

2004
Inhibition of prostate carcinogenesis in probasin/SV40 T antigen transgenic rats by raloxifene, an antiestrogen with anti-androgen action, but not nimesulide, a selective cyclooxygenase-2 inhibitor.
    Carcinogenesis, 2005, Volume: 26, Issue:6

    Topics: Adenocarcinoma; Androgen Antagonists; Androgen-Binding Protein; Animals; Animals, Genetically Modifi

2005
5-aminosalicylic acid in combination with nimesulide inhibits proliferation of colon carcinoma cells in vitro.
    World journal of gastroenterology, 2007, May-28, Volume: 13, Issue:20

    Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Proliferation; Colonic Neop

2007
[Cyclooxygenase (COX)-2 expression in a rat duodenoesophageal reflux model and chemoprevention of adenocarcinoma by the selective COX-2 inhibitor nimesulide].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2007, Volume: 104, Issue:8

    Topics: Adenocarcinoma; Animals; Barrett Esophagus; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprost

2007
Cyclooxygenase-2 inhibitors demonstrate anti-proliferative effects in oesophageal cancer cells by prostaglandin E(2)-independent mechanisms.
    Cancer letters, 2007, Oct-28, Volume: 256, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; C

2007