Compounds > nimbolide
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nimbolide and Breast Neoplasms

nimbolide has been researched along with Breast Neoplasms in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (87.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Arvindh, S; Baba, AB; Gade, DR; Gopal, G; K, C; Nagini, S; Nivetha, R; Reddy, GB; Reddy, KP1
Hussain, MD; Patra, A; Satpathy, S1
Bandi, S; Godugu, C; Gottumukkala, KM; Mondi, SR; Pooladanda, V1
Brittain, SM; Bussiere, DE; Hu, X; Jones, MD; Maimone, TJ; McKenna, JM; Nomura, DK; Olzmann, JA; Ornelas, E; Ou, L; Proudfoot, A; Schirle, M; Spradlin, JN; Tallarico, JA; Thomas, JR; To, M; Ward, CC; Woldegiorgis, M1
Arunakaran, J; Arunkumar, R; Benson, CS; Elumalai, P; Sharmila, G1
Arunakaran, J; Arunkamar, R; Balakrishnan, S; Bhat, FA; Brindha Mercy, A; Elumalai, P; Raja Singh, P; Sharmila, G1
Aggarwal, BB; Gupta, SC; Hema, PS; Nair, M; Park, B; Phromnoi, K; Reuter, S1
Arunakaran, J; Arunkumar, R; Banudevi, S; Benson, CS; Elumalai, P; Gunadharini, DN; Senthilkumar, K; Sharmila, G1

Other Studies

8 other study(ies) available for nimbolide and Breast Neoplasms

ArticleYear
Nimbolide, a Neem Limonoid, Inhibits Angiogenesis in Breast Cancer by Abrogating Aldose Reductase Mediated IGF-1/PI3K/Akt Signalling.
    Anti-cancer agents in medicinal chemistry, 2022, Volume: 22, Issue:14

    Topics: Aldehyde Reductase; Animals; Azadirachta; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Endothelial Cells; Female; Humans; Insulin-Like Growth Factor I; Limonins; Mice; Mice, Nude; MicroRNAs; Molecular Docking Simulation; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction

2022
Nanodelivery and anticancer effect of a limonoid, nimbolide, in breast and pancreatic cancer cells.
    International journal of nanomedicine, 2019, Volume: 14

    Topics: Breast Neoplasms; Cell Death; Cell Line, Tumor; Cryoprotective Agents; Drug Delivery Systems; Drug Liberation; Female; Humans; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Limonins; Nanoparticles; Pancreatic Neoplasms; Particle Size; Polylactic Acid-Polyglycolic Acid Copolymer; Static Electricity

2019
Nimbolide epigenetically regulates autophagy and apoptosis in breast cancer.
    Toxicology in vitro : an international journal published in association with BIBRA, 2018, Volume: 51

    Topics: Acetylation; Antineoplastic Agents; Apoptosis; Autophagy; Beclin-1; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Epigenesis, Genetic; Histone Deacetylase 2; Histones; Humans; Limonins; Membrane Potential, Mitochondrial; Microtubule-Associated Proteins; Proto-Oncogene Proteins c-bcl-2; RNA-Binding Proteins; Signal Transduction; TOR Serine-Threonine Kinases

2018
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.
    Nature chemical biology, 2019, Volume: 15, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Biological Products; Breast Neoplasms; Carrier Proteins; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Humans; Limonins; Proteolysis; Ubiquitin-Protein Ligases

2019
Nimbolide inhibits IGF-I-mediated PI3K/Akt and MAPK signalling in human breast cancer cell lines (MCF-7 and MDA-MB-231).
    Cell biochemistry and function, 2014, Volume: 32, Issue:5

    Topics: beta Catenin; Breast Neoplasms; Cell Line, Tumor; Chromones; Down-Regulation; Female; G1 Phase Cell Cycle Checkpoints; Humans; Insulin Receptor Substrate Proteins; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Limonins; MCF-7 Cells; Mitogen-Activated Protein Kinase Kinases; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; PTEN Phosphohydrolase; Receptor, IGF Type 1; Signal Transduction

2014
Nimbolide inhibits invasion and migration, and down-regulates uPAR chemokine gene expression, in two breast cancer cell lines.
    Cell proliferation, 2014, Volume: 47, Issue:6

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Chemokines; Down-Regulation; Female; Humans; Limonins; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; MCF-7 Cells; Receptors, Urokinase Plasminogen Activator; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-2; Urokinase-Type Plasminogen Activator

2014
Nimbolide sensitizes human colon cancer cells to TRAIL through reactive oxygen species- and ERK-dependent up-regulation of death receptors, p53, and Bax.
    The Journal of biological chemistry, 2011, Jan-14, Volume: 286, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Colonic Neoplasms; Extracellular Signal-Regulated MAP Kinases; HCT116 Cells; HT29 Cells; Humans; Kidney Neoplasms; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Limonins; Lung Neoplasms; Multiple Myeloma; Pancreatic Neoplasms; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand; Tumor Suppressor Protein p53

2011
Induction of apoptosis in human breast cancer cells by nimbolide through extrinsic and intrinsic pathway.
    Toxicology letters, 2012, Nov-30, Volume: 215, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Breast Neoplasms; Caspases; Cell Survival; Cytochromes c; Fas Ligand Protein; Female; Humans; Limonins; MCF-7 Cells; Membrane Potential, Mitochondrial; Neoplasms, Hormone-Dependent; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; TNF-Related Apoptosis-Inducing Ligand

2012