Page last updated: 2024-11-01

nilvadipine and Disease Exacerbation

nilvadipine has been researched along with Disease Exacerbation in 5 studies

Research Excerpts

ExcerptRelevanceReference
"This study reports the findings of the first large-scale Phase III investigator-driven clinical trial to slow the rate of cognitive decline in Alzheimer disease with a dihydropyridine (DHP) calcium channel blocker, nilvadipine."9.27Nilvadipine in mild to moderate Alzheimer disease: A randomised controlled trial. ( Adams, J; Aisen, P; Anastasios, O; Banzi, R; Börjesson-Hanson, A; Breuilh, L; Calais, G; Coen, R; Crawford, F; Cregg, F; Daly, L; de la Sayette, V; Dereeper, O; Devendeville, A; Franceschi, M; Frisoni, G; Gaynor, S; Hendrix, S; Howard, R; Kálmán, J; Kennelly, S; Kenny, RA; Konsta, A; Lavenu, I; Lawlor, B; Lucca, U; Molloy, DW; Mullan, M; Nemni, R; Nenopoulou, S; Nobili, F; O'Dwyer, S; Olde Rikkert, MGM; Pakaski, M; Pasquier, F; Riepe, MW; Segurado, R; Sénéchal, O; Sheikhi, A; Taekema, DG; Tsolaki, M; Tsolaki-Tagaraki, F; Verhey, FR; Walsh, C; Zanetti, O, 2018)
"To assess the effects of nilvadipine on the progression of central visual field defect in retinitis pigmentosa (RP)."9.15Effect of nilvadipine on central visual field in retinitis pigmentosa: a 30-month clinical trial. ( Ito, T; Metoki, T; Miyagawa, Y; Nakazawa, M; Ohguro, H; Takeuchi, K, 2011)
"This study reports the findings of the first large-scale Phase III investigator-driven clinical trial to slow the rate of cognitive decline in Alzheimer disease with a dihydropyridine (DHP) calcium channel blocker, nilvadipine."5.27Nilvadipine in mild to moderate Alzheimer disease: A randomised controlled trial. ( Adams, J; Aisen, P; Anastasios, O; Banzi, R; Börjesson-Hanson, A; Breuilh, L; Calais, G; Coen, R; Crawford, F; Cregg, F; Daly, L; de la Sayette, V; Dereeper, O; Devendeville, A; Franceschi, M; Frisoni, G; Gaynor, S; Hendrix, S; Howard, R; Kálmán, J; Kennelly, S; Kenny, RA; Konsta, A; Lavenu, I; Lawlor, B; Lucca, U; Molloy, DW; Mullan, M; Nemni, R; Nenopoulou, S; Nobili, F; O'Dwyer, S; Olde Rikkert, MGM; Pakaski, M; Pasquier, F; Riepe, MW; Segurado, R; Sénéchal, O; Sheikhi, A; Taekema, DG; Tsolaki, M; Tsolaki-Tagaraki, F; Verhey, FR; Walsh, C; Zanetti, O, 2018)
"To assess the effects of nilvadipine on the progression of central visual field defect in retinitis pigmentosa (RP)."5.15Effect of nilvadipine on central visual field in retinitis pigmentosa: a 30-month clinical trial. ( Ito, T; Metoki, T; Miyagawa, Y; Nakazawa, M; Ohguro, H; Takeuchi, K, 2011)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
de Heus, RAA1
Olde Rikkert, MGM2
Tully, PJ1
Lawlor, BA1
Claassen, JAHR1
Dyer, AH1
Murphy, C1
Segurado, R2
Lawlor, B2
Kennelly, SP1
Kennelly, S1
Howard, R1
Pasquier, F1
Börjesson-Hanson, A1
Tsolaki, M1
Lucca, U1
Molloy, DW1
Coen, R1
Riepe, MW1
Kálmán, J1
Kenny, RA1
Cregg, F1
O'Dwyer, S1
Walsh, C1
Adams, J1
Banzi, R1
Breuilh, L1
Daly, L1
Hendrix, S1
Aisen, P1
Gaynor, S1
Sheikhi, A1
Taekema, DG1
Verhey, FR1
Nemni, R1
Nobili, F1
Franceschi, M1
Frisoni, G1
Zanetti, O1
Konsta, A1
Anastasios, O1
Nenopoulou, S1
Tsolaki-Tagaraki, F1
Pakaski, M1
Dereeper, O1
de la Sayette, V1
Sénéchal, O1
Lavenu, I1
Devendeville, A1
Calais, G1
Crawford, F1
Mullan, M1
Nakazawa, M1
Ohguro, H1
Takeuchi, K1
Miyagawa, Y1
Ito, T1
Metoki, T1
Hanyu, H1
Hirao, K1
Shimizu, S1
Sato, T1
Kiuchi, A1
Iwamoto, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A European Multicentre Double-blind Placebo-controlled Phase III Trial of Nilvadipine in Mild to Moderate Alzheimer's Disease[NCT02017340]Phase 3511 participants (Actual)Interventional2013-04-24Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for nilvadipine and Disease Exacerbation

ArticleYear
Blood Pressure Variability and Progression of Clinical Alzheimer Disease.
    Hypertension (Dallas, Tex. : 1979), 2019, Volume: 74, Issue:5

    Topics: Aged; Alzheimer Disease; Antihypertensive Agents; Blood Pressure Determination; Cognition Disorders;

2019
Is Ongoing Anticholinergic Burden Associated With Greater Cognitive Decline and Dementia Severity in Mild to Moderate Alzheimer's Disease?
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2020, 04-17, Volume: 75, Issue:5

    Topics: Aged; Alzheimer Disease; Apolipoprotein E4; Cholinergic Antagonists; Cognitive Dysfunction; Disabili

2020
Nilvadipine in mild to moderate Alzheimer disease: A randomised controlled trial.
    PLoS medicine, 2018, Volume: 15, Issue:9

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Calcium Channel Blockers; Cognitive Dysfunction; Disease

2018
Effect of nilvadipine on central visual field in retinitis pigmentosa: a 30-month clinical trial.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2011, Volume: 225, Issue:2

    Topics: Administration, Oral; Adult; Aged; Calcium Channel Blockers; Disease Progression; Female; Follow-Up

2011
Nilvadipine prevents cognitive decline of patients with mild cognitive impairment.
    International journal of geriatric psychiatry, 2007, Volume: 22, Issue:12

    Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Cognition Disorders; D

2007