nilvadipine has been researched along with Brain Ischemia in 12 studies
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the effects of nilvadipine and amlodipine on the cerebral ischemia-induced impairment of spatial memory in 8-arm radial maze performance and hippocampal CA1 apoptosis in rats." | 7.72 | Effect of nilvadipine on the cerebral ischemia-induced impairment of spatial memory and hippocampal apoptosis in rats. ( Al-Khatib, IH; Egashira, N; Egawa, T; Fujiwara, M; Irie, K; Ishibashi, D; Iwasaki, K; Kobayashi, H; Mishima, K, 2003) |
| "The protective effect of nilvadipine, a Ca2+ antagonist, on cerebral ischemia was investigated in spontaneously hypertensive rats." | 7.69 | Protective effect of nilvadipine on focal cerebral ischemia in spontaneously hypertensive rats. ( Fukasawa, H; Kawamura, S; Li, Y; Shirasawa, M; Yasui, N, 1996) |
| "The purpose of the present study was to examine the effect of nilvadipine (a dihydropyridine-type calcium entry blocker) on the cerebral circulation, experimental models of cerebral ischemia were used to measure abrupt changes in the cortical cerebral blood flow (CBF) at the 'penumbra' (the boundary region between the anterior cerebral artery (ACA) and the middle cerebral artery (MCA))." | 7.69 | Effects of nilvadipine (a dihydropyridine-type calcium entry blocker) on cerebral blood flow in acute experimental brain ischemia in rats. ( Fujii, K; Maruyama, S; Miyasaka, Y; Nagai, S; Tanaka, R, 1996) |
| "The effects of two dihydropyridine type calcium entry blockers, nilvadipine and nicardipine hydrochloride (nicardipine), on the liberation of free fatty acids (FFAs) were investigated using an experimental model of global cerebral ischemia in rats, and were compared with their pharmacokinetic properties." | 7.68 | Nilvadipine as a neuroprotective calcium entry blocker in a rat model of global cerebral ischemia. A comparative study with nicardipine hydrochloride. ( Fujiwara, T; Kohsaka, M; Mori, J; Satoh, H; Sogabe, K; Takakura, S; Tokuma, Y; Totsuka, Z, 1992) |
| "We studied the efficacy of preischemic and postischemic systemic treatment with a new calcium antagonist nilvadipine in a permanent focal cerebral ischemia model of spontaneously hypertensive rats." | 7.68 | Effects of the calcium antagonist nilvadipine on focal cerebral ischemia in spontaneously hypertensive rats. ( Handa, J; Matsuda, M; Shiino, A; Susumu, T, 1991) |
| "The effects of nilvadipine, a Ca2+ entry blocker, on focal cerebral ischemia were investigated in rats having unilateral middle cerebral artery occlusion." | 7.68 | Effects of a Ca2+ entry blocker (nilvadipine) on acute focal cerebral ischemia in rats. ( Fukasawa, H; Kawamura, S; Shirasawa, M; Yasui, N, 1991) |
| "We investigated the effects of nilvadipine and amlodipine on the cerebral ischemia-induced impairment of spatial memory in 8-arm radial maze performance and hippocampal CA1 apoptosis in rats." | 3.72 | Effect of nilvadipine on the cerebral ischemia-induced impairment of spatial memory and hippocampal apoptosis in rats. ( Al-Khatib, IH; Egashira, N; Egawa, T; Fujiwara, M; Irie, K; Ishibashi, D; Iwasaki, K; Kobayashi, H; Mishima, K, 2003) |
| "The protective effect of nilvadipine, a Ca2+ antagonist, on cerebral ischemia was investigated in spontaneously hypertensive rats." | 3.69 | Protective effect of nilvadipine on focal cerebral ischemia in spontaneously hypertensive rats. ( Fukasawa, H; Kawamura, S; Li, Y; Shirasawa, M; Yasui, N, 1996) |
| "The purpose of the present study was to examine the effect of nilvadipine (a dihydropyridine-type calcium entry blocker) on the cerebral circulation, experimental models of cerebral ischemia were used to measure abrupt changes in the cortical cerebral blood flow (CBF) at the 'penumbra' (the boundary region between the anterior cerebral artery (ACA) and the middle cerebral artery (MCA))." | 3.69 | Effects of nilvadipine (a dihydropyridine-type calcium entry blocker) on cerebral blood flow in acute experimental brain ischemia in rats. ( Fujii, K; Maruyama, S; Miyasaka, Y; Nagai, S; Tanaka, R, 1996) |
| "The effects of two dihydropyridine type calcium entry blockers, nilvadipine and nicardipine hydrochloride (nicardipine), on the liberation of free fatty acids (FFAs) were investigated using an experimental model of global cerebral ischemia in rats, and were compared with their pharmacokinetic properties." | 3.68 | Nilvadipine as a neuroprotective calcium entry blocker in a rat model of global cerebral ischemia. A comparative study with nicardipine hydrochloride. ( Fujiwara, T; Kohsaka, M; Mori, J; Satoh, H; Sogabe, K; Takakura, S; Tokuma, Y; Totsuka, Z, 1992) |
| "The effect of nilvadipine, a dihydropyridine-type calcium entry blocker, on neuronal function during and following ischemia was investigated with a model of focal cerebral ischemia in cats and was compared with that of nicardipine." | 3.68 | Effects of nilvadipine on neuronal function in the ischemic cat brain. ( Furuichi, Y; Kohsaka, M; Mori, J; Satoh, H; Takakura, S, 1992) |
| "The effects of nilvadipine, a dihydropyridine type calcium channel blocker, on cerebral infarction induced by focal brain ischemia was studied in rats." | 3.68 | Nilvadipine, a new calcium channel blocker, reduces ischemic brain injury in rats. ( Handa, J; Mori, J; Satoh, H; Shiino, A; Susumu, T; Takakura, S, 1991) |
| "We investigated the effects of nilvadipine, a calcium antagonist, on cerebral ischemia in rats." | 3.68 | Attenuated neuropathology by nilvadipine after middle cerebral artery occlusion in rats. ( Fukasawa, H; Kawamura, S; Shirasawa, M; Yasui, N, 1991) |
| "We studied the efficacy of preischemic and postischemic systemic treatment with a new calcium antagonist nilvadipine in a permanent focal cerebral ischemia model of spontaneously hypertensive rats." | 3.68 | Effects of the calcium antagonist nilvadipine on focal cerebral ischemia in spontaneously hypertensive rats. ( Handa, J; Matsuda, M; Shiino, A; Susumu, T, 1991) |
| "The effects of nilvadipine, a Ca2+ entry blocker, on focal cerebral ischemia were investigated in rats having unilateral middle cerebral artery occlusion." | 3.68 | Effects of a Ca2+ entry blocker (nilvadipine) on acute focal cerebral ischemia in rats. ( Fukasawa, H; Kawamura, S; Shirasawa, M; Yasui, N, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 8 (66.67) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iwasaki, K | 2 |
| Mishima, K | 2 |
| Egashira, N | 2 |
| Al-Khatib, IH | 1 |
| Ishibashi, D | 1 |
| Irie, K | 1 |
| Kobayashi, H | 1 |
| Egawa, T | 1 |
| Fujiwara, M | 2 |
| Takahara, A | 1 |
| Konda, T | 1 |
| Enomoto, A | 1 |
| Kondo, N | 1 |
| Takagaki, Y | 1 |
| Yoshimitsu, Y | 1 |
| Hatip-Al-Khatib, I | 1 |
| Kawamura, S | 3 |
| Li, Y | 1 |
| Shirasawa, M | 3 |
| Yasui, N | 3 |
| Fukasawa, H | 3 |
| Tanaka, R | 1 |
| Miyasaka, Y | 1 |
| Maruyama, S | 1 |
| Nagai, S | 1 |
| Fujii, K | 1 |
| Takakura, S | 3 |
| Sogabe, K | 1 |
| Satoh, H | 4 |
| Mori, J | 3 |
| Fujiwara, T | 1 |
| Totsuka, Z | 1 |
| Tokuma, Y | 1 |
| Kohsaka, M | 2 |
| Furuichi, Y | 1 |
| Susumu, T | 2 |
| Shiino, A | 2 |
| Handa, J | 2 |
| Matsuda, M | 1 |
| Kuwaki, T | 1 |
| Ono, T | 1 |
| Shibayama, F | 1 |
| Yamashita, T | 1 |
| Nishimura, T | 1 |
12 other studies available for nilvadipine and Brain Ischemia
| Article | Year |
|---|---|
Effect of nilvadipine on the cerebral ischemia-induced impairment of spatial memory and hippocampal apoptosis in rats.
Topics: Animals; Apoptosis; Brain Ischemia; Calcium Channel Blockers; Calibration; Genes, bcl-2; Glyceraldeh | 2003 |
Neuroprotective effects of a dual L/N-type Ca(2+) channel blocker cilnidipine in the rat focal brain ischemia model.
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Typ | 2004 |
Nilvadipine prevents the impairment of spatial memory induced by cerebral ischemia combined with beta-amyloid in rats.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Brain Ischemia; Calcium Channel Blockers; Male; Maze Lear | 2007 |
Protective effect of nilvadipine on focal cerebral ischemia in spontaneously hypertensive rats.
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Cerebral Infarction; Dose-Response Relationship, | 1996 |
Effects of nilvadipine (a dihydropyridine-type calcium entry blocker) on cerebral blood flow in acute experimental brain ischemia in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain Ischemia; Calcium Channel Blockers; Cerebrov | 1996 |
Nilvadipine as a neuroprotective calcium entry blocker in a rat model of global cerebral ischemia. A comparative study with nicardipine hydrochloride.
Topics: Animals; Brain; Brain Ischemia; Calcium Channel Blockers; Decerebrate State; Fatty Acids, Nonesterif | 1992 |
Effects of nilvadipine on neuronal function in the ischemic cat brain.
Topics: Animals; Brain; Brain Ischemia; Calcium Channel Blockers; Cats; Cerebrovascular Circulation; Evoked | 1992 |
Nilvadipine, a new calcium channel blocker, reduces ischemic brain injury in rats.
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Cerebral Infarction; Nicardipine; Nifedipine; Rat | 1991 |
Attenuated neuropathology by nilvadipine after middle cerebral artery occlusion in rats.
Topics: Animals; Arterial Occlusive Diseases; Brain; Brain Ischemia; Calcium Channel Blockers; Cerebral Arte | 1991 |
Effects of the calcium antagonist nilvadipine on focal cerebral ischemia in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain Ischemia; Calcium Channel Blockers; Cerebral Arteries; Cerebral Infar | 1991 |
Effects of a Ca2+ entry blocker (nilvadipine) on acute focal cerebral ischemia in rats.
Topics: Acute Disease; Animals; Brain; Brain Edema; Brain Ischemia; Calcium Channel Blockers; Cerebral Infar | 1991 |
Nilvadipine attenuates ischemic degradation of gerbil brain cytoskeletal proteins.
Topics: Animals; Brain; Brain Ischemia; Calmodulin-Binding Proteins; Clathrin; Cytoskeletal Proteins; Dose-R | 1989 |