Page last updated: 2024-08-23

nigericin and Innate Inflammatory Response

nigericin has been researched along with Innate Inflammatory Response in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (13.79)29.6817
2010's10 (34.48)24.3611
2020's15 (51.72)2.80

Authors

AuthorsStudies
Guan, Q; Han, C; Li, W; Ruan, S; Sheng, Y; Wang, J; Yang, Y; Zhang, C; Zhou, X1
Chen, F; Gao, H; Jiang, R; Liu, Y; Liu, Z; Mei, J; Wang, B1
Chen, W; Yan, J; Yao, H; Yin, L1
Li, Y; Miao, HT; Song, RX; Wu, ZY; Xin, Y; Zhang, DX; Zhang, LM; Zhao, XC; Zheng, WC1
Bao, P; Chen, R; Chen, X; Ge, J; Guan, L; Huang, Z; Li, M; Liang, Y; Su, Y; Xiao, Z; Yu, Y; Yu, Z1
Chen, D; Chen, G; Lin, J; Lin, Y; Liu, A; Luo, T; Ouyang, D; Pan, H; Qin, M; Zhou, X1
Chen, CY; Chen, HW; Lii, CK; Lo, CW; Yen, CC1
Bao, X; Ji, J; Jiang, S; Liu, N; Liu, X; Tang, L; Wang, C; Yang, D; Zhang, Q; Zhao, D1
Hägglund, P; Hallberg, LAE; Hawkins, CL; Jensen, M; Thorsen, NW1
Fang, G; Huang, T; Lan, C; Li, X; Peng, K; Qiu, C; Wang, Z; Yang, F; Yang, Y1
He, Y; Huang, D; Jia, N; Pei, C; Shen, Z; Shi, S; Wang, X; Wang, Y; Wang, Z; Wu, Y; Zhao, S1
Bates, MA; Gavrilin, MA; Gilley, KN; Holian, A; Pestka, JJ; Rajasinghe, LD; Wee, J; Wierenga, KA1
Ai, Y; Bai, Z; Chen, Y; Hou, X; Li, R; Shi, W; Sun, H; Wang, C; Wang, JB; Wang, Z; Xiao, X; Xu, G; Zhan, X1
Du, GH; Fang, LH; Lyu, Y; Wang, DS; Wang, SB; Yan, LY; Yang, DZ1
Fu, M; Huang, X; Li, X; Liu, C; Qian, Y; Zhou, Z1
Brough, D; Green, J; Lopez-Castejon, G; Wellens, R; Yu, S1
Cho, YI; Gu, S; Kim, DH; Lee, SM; Seo, DW; Yi, YJ1
Cohen, MS; Dubey, S; Karan, D; Nagarkatti, M; Nagarkatti, P; Yoon, H1
Avouac, J; Bennana, E; Chiocchia, G; Devauchelle, V; Ea, HK; Gonzalez, V; Gottenberg, JE; Guillonneau, F; Mistou, S; Mouasni, S; Schmitt, A; Tourneur, L1
Kelly, P; Meade, KG; O'Farrelly, C1
Deng, H; Li, Y; Liu, T; Song, D; Wei, W; Zeng, Q; Zhao, X1
Han, JW; Heo, KH; Jeong, JH; Kang, TB; Kwak, SB; Lee, KH; Shim, DW; Shin, WY; Sim, EJ1
Bilen, S; Biswas, G; Hikima, J; Kono, T; Sakai, M1
Busso, N; Nomura, J; So, A; Tamura, M1
Gevaert, K; Kanneganti, TD; Lamkanfi, M; Núñez, G; Van Damme, P; Vandekerckhove, J; Vanden Berghe, T; Vandenabeele, P; Vanoverberghe, I1
Bscheider, M; Dostert, C; Endres, S; Gross, O; Hannesschläger, N; Hartmann, G; Mocsai, A; Poeck, H; Ruland, J; Schweighoffer, E; Tardivel, A; Tschopp, J; Tybulewicz, V1
Chen, S; Hu, Y; Mao, K; Meng, G; Sun, B; Sun, S; Tao, Z; Wu, X; Yang, C; Zeng, Y1
Dixit, VM; Lee, WP; Mariathasan, S; McBride, J; Monack, DM; Newton, K; O'Rourke, K; Roose-Girma, M; Weinrauch, Y; Weiss, DS1
Gabel, CA; Griffiths, RJ; Koller, BH; Labasi, J; Perregaux, DG; Petrushova, N; Solle, M; Stam, E1

Other Studies

29 other study(ies) available for nigericin and Innate Inflammatory Response

ArticleYear
Antcin A alleviates pyroptosis and inflammatory response in Kupffercells of non-alcoholic fatty liver disease by targeting NLRP3.
    International immunopharmacology, 2021, Volume: 100

    Topics: Animals; Caspase 1; Cell Survival; Cells, Cultured; Diet, High-Fat; Disease Models, Animal; Inflammasomes; Inflammation; Interleukin-1beta; Kupffer Cells; Lipopolysaccharides; Liver; Mice; Mice, Inbred C57BL; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Non-alcoholic Fatty Liver Disease; Pyroptosis; Steroids

2021
Emodin relieves the inflammation and pyroptosis of lipopolysaccharide-treated 1321N1 cells by regulating methyltransferase-like 3 -mediated NLR family pyrin domain containing 3 expression.
    Bioengineered, 2022, Volume: 13, Issue:3

    Topics: Caspase 1; Emodin; Humans; Inflammation; Interleukin-10; Interleukin-6; Lipopolysaccharides; Methyltransferases; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Pyrin Domain; Pyroptosis; Tumor Necrosis Factor-alpha

2022
Picroside II alleviates DSS-induced ulcerative colitis by suppressing the production of NLRP3 inflammasomes through NF-κB signaling pathway.
    Immunopharmacology and immunotoxicology, 2022, Volume: 44, Issue:3

    Topics: Adenosine Triphosphate; Animals; Caspase 1; Cinnamates; Colitis, Ulcerative; Dextran Sulfate; Inflammasomes; Inflammation; Iridoid Glucosides; Lipopolysaccharides; Mice; NF-kappa B; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction

2022
STING mediates neuroinflammatory response by activating NLRP3-related pyroptosis in severe traumatic brain injury.
    Journal of neurochemistry, 2022, Volume: 162, Issue:5

    Topics: Animals; Brain Injuries, Traumatic; Inflammasomes; Inflammation; Membrane Proteins; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis

2022
Translocation of gasdermin D induced mitochondrial injury and mitophagy mediated quality control in lipopolysaccharide related cardiomyocyte injury.
    Clinical and translational medicine, 2022, Volume: 12, Issue:8

    Topics: Heart Diseases; Humans; Inflammation; Lipopolysaccharides; Mitochondria; Mitochondrial Permeability Transition Pore; Mitophagy; Myocytes, Cardiac; Nigericin; Phosphate-Binding Proteins; Pore Forming Cytotoxic Proteins; Quality Control

2022
Corilagin Restrains NLRP3 Inflammasome Activation and Pyroptosis through the ROS/TXNIP/NLRP3 Pathway to Prevent Inflammation.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Adenine; Adenosine Triphosphate; Anti-Inflammatory Agents; Antioxidants; Arthritis, Gouty; Caspase 1; Humans; Hydrolyzable Tannins; Imiquimod; Inflammasomes; Inflammation; Interleukin-1beta; Lactate Dehydrogenases; Lipopolysaccharides; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Nucleosides; Propidium; Pyroptosis; Reactive Oxygen Species; Uric Acid

2022
Benzyl isothiocyanate attenuates activation of the NLRP3 inflammasome in Kupffer cells and improves diet-induced steatohepatitis.
    Toxicology and applied pharmacology, 2023, 03-01, Volume: 462

    Topics: Animals; Cholesterol; Diet, High-Fat; Inflammasomes; Inflammation; Insulin Resistance; Interleukin-1beta; Kupffer Cells; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Non-alcoholic Fatty Liver Disease

2023
    Frontiers in immunology, 2023, Volume: 14

    Topics: Cytokines; Endothelial Cells; Humans; Inflammasomes; Inflammation; Interleukin-18; Lipopolysaccharides; MicroRNAs; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Pneumonia; Pyroptosis; RNA, Circular; Sepsis

2023
New insight into the composition of extracellular traps released by macrophages exposed to different types of inducers.
    Free radical biology & medicine, 2023, Volume: 202

    Topics: DNA; Extracellular Traps; Histones; Humans; Inflammation; Macrophages; Neutrophils; Nigericin; Proteomics; Tumor Necrosis Factor-alpha

2023
Amentoflavone mitigates doxorubicin-induced cardiotoxicity by suppressing cardiomyocyte pyroptosis and inflammation through inhibition of the STING/NLRP3 signalling pathway.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 117

    Topics: Animals; Apoptosis Regulatory Proteins; Body Weight; Breast Neoplasms; Cardiotoxicity; Doxorubicin; Female; Humans; Inflammation; Mice; Myocytes, Cardiac; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Rats; Rats, Sprague-Dawley

2023
Eleutheroside E from pre-treatment of Acanthopanax senticosus (Rupr.etMaxim.) Harms ameliorates high-altitude-induced heart injury by regulating NLRP3 inflammasome-mediated pyroptosis via NLRP3/caspase-1 pathway.
    International immunopharmacology, 2023, Volume: 121

    Topics: Altitude; Animals; Anti-Inflammatory Agents; Caspase 1; Eleutherococcus; Heart Injuries; Hypoxia; Inflammasomes; Inflammation; Male; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Prospective Studies; Pyroptosis; Rats

2023
Docosahexaenoic Acid Suppresses Silica-Induced Inflammasome Activation and IL-1 Cytokine Release by Interfering With Priming Signal.
    Frontiers in immunology, 2019, Volume: 10

    Topics: Animals; Cell Line; Docosahexaenoic Acids; HEK293 Cells; Humans; Inflammasomes; Inflammation; Interleukin-1; Lung; Macrophages; Mice; Mice, Inbred C57BL; Nigericin; RAW 264.7 Cells; Silicon Dioxide

2019
Dehydrocostus lactone inhibits NLRP3 inflammasome activation by blocking ASC oligomerization and prevents LPS-mediated inflammation in vivo.
    Cellular immunology, 2020, Volume: 349

    Topics: Adult; Animals; Apoptosis Regulatory Proteins; Calcium-Binding Proteins; CARD Signaling Adaptor Proteins; Caspase 1; Chemotaxis, Leukocyte; DNA-Binding Proteins; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Female; Humans; Inflammasomes; Inflammation; Interleukin-1beta; Lactones; Leukocytes, Mononuclear; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Neutrophils; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Poly I-C; Polymerization; Sesquiterpenes; Specific Pathogen-Free Organisms; Uric Acid

2020
Formononetin ameliorates myocardial ischemia/reperfusion injury in rats by suppressing the ROS-TXNIP-NLRP3 pathway.
    Biochemical and biophysical research communications, 2020, 05-07, Volume: 525, Issue:3

    Topics: Animals; Animals, Newborn; Apoptosis; Biomarkers; Cell Cycle Proteins; Heart Function Tests; Inflammasomes; Inflammation; Isoflavones; Lipopolysaccharides; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Protein Binding; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction

2020
Heat shock protein 90 inhibitors suppress pyroptosis in THP-1 cells.
    The Biochemical journal, 2020, 10-30, Volume: 477, Issue:20

    Topics: Benzoquinones; Caspase 1; Cell Survival; HSP72 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Inflammasomes; Inflammation; Intracellular Signaling Peptides and Proteins; Lactams, Macrocyclic; Lipopolysaccharides; Macrolides; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphate-Binding Proteins; Proteasome Endopeptidase Complex; Protein Stability; Pyroptosis; Signal Transduction; THP-1 Cells; Up-Regulation

2020
Bafilomycin A1 enhances NLRP3 inflammasome activation in human monocytes independent of lysosomal acidification.
    The FEBS journal, 2021, Volume: 288, Issue:10

    Topics: Caspase 1; Enzyme Inhibitors; Gene Expression Regulation; Humans; Hydrogen-Ion Concentration; Inflammasomes; Inflammation; Interleukin-1beta; Lipopolysaccharides; Lysosomes; Macrolides; Monocytes; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Primary Cell Culture; Proton-Translocating ATPases; Receptor-Interacting Protein Serine-Threonine Kinases; Signal Transduction; THP-1 Cells

2021
A hot-water extract of Sanguisorba officinalis ameliorates endotoxin-induced septic shock by inhibiting inflammasome activation.
    Microbiology and immunology, 2018, Volume: 62, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Caspase 1; Cytokines; Disease Models, Animal; Endotoxins; Female; Herbal Medicine; Inflammasomes; Inflammation; Interleukin-1beta; Lipopolysaccharides; Listeria monocytogenes; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nigericin; NLR Proteins; Plant Extracts; Plant Roots; Republic of Korea; Salmonella typhimurium; Sanguisorba; Shock, Septic; Survival Rate

2018
Withaferin A Associated Differential Regulation of Inflammatory Cytokines.
    Frontiers in immunology, 2018, Volume: 9

    Topics: Adenosine Triphosphate; Chemokines; Cytokines; Gene Expression Profiling; Gene Expression Regulation; Humans; Inflammasomes; Inflammation; NF-kappa B; Nigericin; Oligonucleotide Array Sequence Analysis; Plant Extracts; Promoter Regions, Genetic; Signal Transduction; THP-1 Cells; Withanolides

2018
The classical NLRP3 inflammasome controls FADD unconventional secretion through microvesicle shedding.
    Cell death & disease, 2019, 02-25, Volume: 10, Issue:3

    Topics: Animals; Arthritis, Rheumatoid; Caspase 1; Cell Line, Tumor; Cell-Derived Microparticles; Fas-Associated Death Domain Protein; Gout; Humans; Immunity, Innate; Inflammasomes; Inflammation; Interleukin-1beta; Macrophages; Monocytes; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Potassium Channels; Pyroptosis

2019
Non-canonical Inflammasome-Mediated IL-1β Production by Primary Endometrial Epithelial and Stromal Fibroblast Cells Is NLRP3 and Caspase-4 Dependent.
    Frontiers in immunology, 2019, Volume: 10

    Topics: Animals; Caspases, Initiator; Cattle; Cattle Diseases; Cells, Cultured; Endometritis; Endometrium; Epithelial Cells; Female; Fibroblasts; Inflammasomes; Inflammation; Interleukin-1beta; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein

2019
Synthesis and Biological Evaluation of Fangchinoline Derivatives as Anti-Inflammatory Agents through Inactivation of Inflammasome.
    Molecules (Basel, Switzerland), 2019, Mar-23, Volume: 24, Issue:6

    Topics: Anti-Inflammatory Agents; Benzylisoquinolines; Caspase 1; Cell Line; Gene Expression Regulation; Humans; Inflammasomes; Inflammation; Interleukin-1beta; Lipopolysaccharides; NF-kappa B; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Transcription Factor RelA

2019
Anti-inflammatory effect of emodin via attenuation of NLRP3 inflammasome activation.
    International journal of molecular sciences, 2015, Apr-10, Volume: 16, Issue:4

    Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Carrier Proteins; Emodin; Endotoxins; Inflammasomes; Inflammation; Interleukin-1beta; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Oxygenases; Silicon Dioxide

2015
Inflammatory immune response by lipopolysaccharide-responsive nucleotide binding oligomerization domain (NOD)-like receptors in the Japanese pufferfish (Takifugu rubripes).
    Developmental and comparative immunology, 2016, Volume: 55

    Topics: Amino Acid Sequence; Animals; Antigens, Bacterial; Cells, Cultured; Computational Biology; Fish Proteins; Gene Expression Regulation; Head Kidney; Humans; Inflammation; Lactobacillus; Leukocytes; Lipopolysaccharides; Molecular Sequence Data; Nigericin; Nod Signaling Adaptor Proteins; Phylogeny; Tetraodontiformes; Vibrio; Vibrio Infections

2016
Intracellular ATP Decrease Mediates NLRP3 Inflammasome Activation upon Nigericin and Crystal Stimulation.
    Journal of immunology (Baltimore, Md. : 1950), 2015, Dec-15, Volume: 195, Issue:12

    Topics: Adenosine Triphosphate; Animals; Caspase 1; Cells, Cultured; Deoxyglucose; Humans; Inflammasomes; Inflammation; Interleukin-1beta; Intracellular Space; Macrophages; Membrane Glycoproteins; Mice, Inbred C57BL; Nerve Tissue Proteins; Nigericin; Uric Acid

2015
Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes.
    Molecular & cellular proteomics : MCP, 2008, Volume: 7, Issue:12

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Aspartic Acid; Caspase 1; Caspase 3; Caspase 7; Cell Death; Cytokines; Enzyme Activation; Inflammation; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Nigericin; Peptides; Protein Processing, Post-Translational; Proteome; Proteomics; Salmonella; Substrate Specificity

2008
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence.
    Nature, 2009, May-21, Volume: 459, Issue:7245

    Topics: Animals; Candida albicans; Carrier Proteins; Caspase 1; Enzyme Activation; Humans; Inflammation; Interleukin-1beta; Intracellular Signaling Peptides and Proteins; Macrophages; Mice; Monocytes; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Potassium; Protein-Tyrosine Kinases; Reactive Oxygen Species; Signal Transduction; Syk Kinase

2009
Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production.
    Journal of immunology (Baltimore, Md. : 1950), 2010, Dec-15, Volume: 185, Issue:12

    Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Antioxidants; Carrier Proteins; Caspase 1; HEK293 Cells; Humans; Inflammasomes; Inflammation; Interleukin-1beta; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Neutrophil Infiltration; Neutrophils; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Peritonitis; Reactive Oxygen Species; Silicon Dioxide; Uric Acid

2010
Cryopyrin activates the inflammasome in response to toxins and ATP.
    Nature, 2006, Mar-09, Volume: 440, Issue:7081

    Topics: Adenosine Triphosphate; Animals; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Carrier Proteins; Caspase 1; Cytoskeletal Proteins; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Inflammation; Interleukin-1; Intracellular Signaling Peptides and Proteins; Listeria monocytogenes; Macrophages; Marine Toxins; Mice; Multiprotein Complexes; NF-kappa B; Nigericin; NLR Family, Pyrin Domain-Containing 3 Protein; Nod2 Signaling Adaptor Protein; Oxocins; Signal Transduction; Staphylococcus aureus; Toll-Like Receptors; Toxins, Biological

2006
Altered cytokine production in mice lacking P2X(7) receptors.
    The Journal of biological chemistry, 2001, Jan-05, Volume: 276, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Cyclooxygenase 2; Enzyme Induction; Fluorescent Dyes; Gene Deletion; Gene Targeting; Inflammation; Interleukin-1; Interleukin-6; Isoenzymes; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Knockout; Nigericin; Prostaglandin-Endoperoxide Synthases; Protein Precursors; Protein Processing, Post-Translational; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2X7

2001