niga-ichigoside-f1 and Inflammation

Here, we evaluate the anti-inflammatory and wound-healing effects of methanolic crude extract obtained from aerial parts (leaves and branches) of Rubus imperialis Chum. Schl. (Rosaceae) and the pure compound niga-ichigoside F1. Anti-inflammatory activity was determined in vivo and in vitro, and the healing effect was evaluated in surgical lesions in mice skin. The 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) assay and H

Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Carrageenan; Cell Line; Chemotaxis, Leukocyte; Disease Models, Animal; Dose-Response Relationship, Drug; Hydrogen Peroxide; Inflammation; Lipopolysaccharides; Macrophages, Peritoneal; Male; Methanol; Mice, Inbred BALB C; Neutrophil Infiltration; Neutrophils; Oxidative Stress; Phytotherapy; Picrates; Plant Components, Aerial; Plant Extracts; Plants, Medicinal; Rubus; Saponins; Skin; Solvents; Wound Healing; Wounds, Penetrating