nifurtimox and Hemolysis

nifurtimox has been researched along with Hemolysis* in 1 studies

Other Studies

1 other study(ies) available for nifurtimox and Hemolysis

Article	Year
Bacterial chemistry. VI. Biological activities and cytotoxicity of 1,3-dihydro-2H-indol-2-one derivatives. Biological research, 1992, Volume: 25, Issue:1 The biosynthetic pigment from Chromobacterium violaceum BB-78, 1,3-dihydro-2H-indol-2-one and its derivatives exhibit biological activities such as antimicrobial action, low hemolytic effects on red blood cells and in vitro trypanocide activity. A relatively high cytotoxicity on V-79 hamster fibroblast cells of the biosynthetic pigment was found, although with the methylol derivative the toxicity was almost eliminated. The methylol derivative exhibited similar toxicity as Nifurtimox, a known, commercial trypanocide compound. Topics: Animals; Anti-Bacterial Agents; Bacteria; Cell Line; Cell Survival; Chromobacterium; Cricetinae; Fibroblasts; Hemolysis; Indoles; Microbial Sensitivity Tests; Nifurtimox; Pigments, Biological; Trypanosoma cruzi	1992

Article

Year

Bacterial chemistry. VI. Biological activities and cytotoxicity of 1,3-dihydro-2H-indol-2-one derivatives.

Biological research, 1992, Volume: 25, Issue:1

The biosynthetic pigment from Chromobacterium violaceum BB-78, 1,3-dihydro-2H-indol-2-one and its derivatives exhibit biological activities such as antimicrobial action, low hemolytic effects on red blood cells and in vitro trypanocide activity. A relatively high cytotoxicity on V-79 hamster fibroblast cells of the biosynthetic pigment was found, although with the methylol derivative the toxicity was almost eliminated. The methylol derivative exhibited similar toxicity as Nifurtimox, a known, commercial trypanocide compound.

Topics: Animals; Anti-Bacterial Agents; Bacteria; Cell Line; Cell Survival; Chromobacterium; Cricetinae; Fibroblasts; Hemolysis; Indoles; Microbial Sensitivity Tests; Nifurtimox; Pigments, Biological; Trypanosoma cruzi

1992