Page last updated: 2024-11-01

niflumic acid and Asthma

niflumic acid has been researched along with Asthma in 8 studies

Niflumic Acid: An analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"The effects of niflumic acid (NA), a relatively specific blocker of calcium-activated chloride channel (CLCA), on goblet cell hyperplasia, eosinophil accumulation, and airway hyperresponsiveness were evaluated after IL-13 instillation into the airways."7.73Niflumic acid suppresses interleukin-13-induced asthma phenotypes. ( Aizawa, H; Fukuyama, S; Inoue, H; Matsumoto, K; Matsumoto, T; Matsumura, M; Nakanishi, Y; Nakano, T; Tsuda, M, 2006)
"To evaluate the inhibiting effect of niflumic acid (NFA), an inhibitor of calcium-activated chloride channel (ClCa) on airway epithelium, on the airway hyperresponsiveness in asthmatic mice."7.72[The inhibiting effect of niflumic acid on airway hyperresponsiveness in asthmatic mice]. ( Cheng, JH; Gao, F; Li, Y; Qi, HW; Song, LQ; Zhang, LN, 2004)
"The effects of niflumic acid (NA), a relatively specific blocker of calcium-activated chloride channel (CLCA), on goblet cell hyperplasia, eosinophil accumulation, and airway hyperresponsiveness were evaluated after IL-13 instillation into the airways."3.73Niflumic acid suppresses interleukin-13-induced asthma phenotypes. ( Aizawa, H; Fukuyama, S; Inoue, H; Matsumoto, K; Matsumoto, T; Matsumura, M; Nakanishi, Y; Nakano, T; Tsuda, M, 2006)
"To evaluate the inhibiting effect of niflumic acid (NFA), an inhibitor of calcium-activated chloride channel (ClCa) on airway epithelium, on the airway hyperresponsiveness in asthmatic mice."3.72[The inhibiting effect of niflumic acid on airway hyperresponsiveness in asthmatic mice]. ( Cheng, JH; Gao, F; Li, Y; Qi, HW; Song, LQ; Zhang, LN, 2004)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rievaj, J1
Davidson, C1
Nadeem, A1
Hollenberg, M1
Duszyk, M1
Vliagoftis, H1
Kondo, M1
Nakata, J1
Arai, N1
Izumo, T1
Tagaya, E1
Takeyama, K1
Tamaoki, J1
Nagai, A1
Song, LQ1
Li, Y1
Zhang, LN1
Gao, F1
Cheng, JH1
Qi, HW1
McNamara, N1
Gallup, M1
Khong, A1
Sucher, A1
Maltseva, I1
Fahy, J1
Basbaum, C1
Nakano, T1
Inoue, H1
Fukuyama, S1
Matsumoto, K1
Matsumura, M1
Tsuda, M1
Matsumoto, T1
Aizawa, H1
Nakanishi, Y1
Erle, DJ1
Zhen, G1
Melton, L1
Leynadier, F1
Perrault, M1

Other Studies

8 other studies available for niflumic acid and Asthma

ArticleYear
Allergic sensitization enhances anion current responsiveness of murine trachea to PAR-2 activation.
    Pflugers Archiv : European journal of physiology, 2012, Volume: 463, Issue:3

    Topics: Amiloride; Animals; Asthma; Benzoates; Bestrophins; Chloride Channels; Eye Proteins; Hypersensitivit

2012
Niflumic acid inhibits goblet cell degranulation in a guinea pig asthma model.
    Allergology international : official journal of the Japanese Society of Allergology, 2012, Volume: 61, Issue:1

    Topics: Animals; Asthma; Bronchial Provocation Tests; Cell Degranulation; Disease Models, Animal; Goblet Cel

2012
[The inhibiting effect of niflumic acid on airway hyperresponsiveness in asthmatic mice].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2004, Volume: 27, Issue:2

    Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Endothelin-1; In Vitro Tec

2004
Adenosine up-regulation of the mucin gene, MUC2, in asthma.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:14

    Topics: Adenosine; Asthma; ErbB Receptors; Humans; Ion Channels; Mucin-2; Mucins; Niflumic Acid; Phosphoryla

2004
Niflumic acid suppresses interleukin-13-induced asthma phenotypes.
    American journal of respiratory and critical care medicine, 2006, Jun-01, Volume: 173, Issue:11

    Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Chloride Channels; Eosinophils; Goblet Cells; Hyperpl

2006
The asthma channel? Stay tuned . . .
    American journal of respiratory and critical care medicine, 2006, Jun-01, Volume: 173, Issue:11

    Topics: Animals; Asthma; Chloride Channels; Humans; Interleukin-13; Mice; Mucoproteins; Niflumic Acid; Respi

2006
Does mucus hypersecretion matter in airway disease?
    Lancet (London, England), 2002, Jun-01, Volume: 359, Issue:9321

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Female; Humans; Male; Mice; Mucus; Niflumi

2002
[Anti-inflammatory agents in current therapeutics].
    La Revue du praticien, 1975, Jan-21, Volume: 25, Issue:5

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoi

1975