Page last updated: 2024-09-03

nifekalant hydrochloride and Ventricular Fibrillation

nifekalant hydrochloride has been researched along with Ventricular Fibrillation in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (16.13)18.2507
2000's14 (45.16)29.6817
2010's11 (35.48)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Kubota, T; Okura, H; Takasugi, N1
Tagami, T; Yasunaga, H; Yokota, H1
Chuma, M; Imai, T; Ishizawa, K; Izawa-Ishizawa, Y; Koga, T; Kondo, Y; Koyama, T; Kurata, Y; Nakura, H; Niimura, T; Sato, S; Sendo, T; Takechi, K; Tanaka, S; Zamami, Y1
Aibara, K; Goto, K; Harayama, N; Isa, Y; Kamochi, M; Nagata, K; Nihei, S; Sata, T1
Iacovidou, N; Karlis, G; Lelovas, P; Mentzelopoulos, S; Niforopoulou, P; Papalois, A; Siafaka, I; Xanthos, T1
Aibara, K; Harayama, N; Kamochi, M; Nagata, K; Nihei, S; Sata, T1
Fukuda, R; Fushimi, K; Ishinokami, S; Kitahashi, A; Matsui, H; Oyanagi, M; Tagami, T; Unemoto, K; Yasunaga, H1
Maeda, K; Nakagawa, E; Takagi, M; Tatsumi, H; Yoshiyama, M1
Abe, A; Ikeda, T; Ishiguro, H; Mera, H; Miwa, Y; Miyakoshi, M; Shimizu, H; Tsukada, T; Yoshino, H; Yusu, S1
Amino, M; Honda, T; Kasanuki, H; Kato, R; Katoh, T; Matsudo, Y; Ogawa, S; Sagara, K; Shiga, T; Takahashi, A; Takano, T; Tanaka, K; Urashima, M1
Akieda, K; Amino, M; Fujibayashi, D; Fukushima, T; Hashida, T; Higami, S; Inokuchi, S; Kodama, I; Morita, S; Opthof, T; Otsuka, H; Shima, M; Tamura, K; Tanabe, T; Uemura, S; Yoshioka, K1
Cong, LH; Ji, XF; Li, CS; Wang, S; Yang, L1
Hazui, H; Kada, A; Nonogi, H; Ohashi, J; Sase, K; Sawano, H; Ukai, I; Yasuda, S; Yokoyama, H1
Nagao, K1
Ohnishi, S1
Amino, M; Ban, K; Deguchi, Y; Fujikura, H; Goto, S; Handa, S; Inokuchi, S; Iwase, H; Iwata, O; Marutani, Y; Morita, S; Nakagawa, Y; Shiina, Y; Tanabe, T; Yamamoto, I; Yoshioka, K1
Fujino, T; Igarashi, M; Kobayashi, K; Koyama, N; Okano, Y; Otsuka, T; Sasamoto, S; Sasao, K; Sugino, K; Toyoda, M; Yosiwara, K1
Ando, J; Iwabuchi, M; Kakishita, M; Komura, Y; Nishiyama, K; Nobuyoshi, M; Nosaka, H; Sakai, K; Yasumoto, H; Yokoi, H1
Kasanuki, H; Katoh, T; Matsuda, N; Mitamura, H; Ogawa, S; Takano, T1
Hamano, K; Murakami, M; Nishida, M; Okada, H1
Ebina, T; Hibi, K; Kimura, K; Kosuge, M; Kosuge, T; Moriwaki, Y; Sugiyama, M; Sumita, S; Suzuki, N; Tahara, Y; Toyama, H; Umemura, S1
Sugi, K1
Amino, M; Deguchi, Y; Ikari, Y; Kanda, S; Kodama, I; Kohzuma, K; Matsuzaki, A; Sugimoto, A; Tanabe, T; Usui, K; Yoshioka, K1
Kamakura, S; Kawamura, A; Kurita, T; Miyazaki, S; Morii, I; Nonogi, H; Ohashi, J; Shimizu, W; Yasuda, S1
Homma, M; Inoue, J; Kato, H; Murata, K; Ogasawara, T; Takeuchi, S1
Awaji, T; Haruno, A; Hashimoto, K; Hirasawa, A; Wu, Z; Xue, Y1
Black, SC; Chi, L; Friedrichs, GS; Lucchesi, BR; Manley, PJ1
Basler, GC; Black, SC; Chi, L; Friedrichs, GS; Gralinski, MR; Johnson, CR; Lucchesi, BR; Mu, DX; Pewitt, SR1
Kanese, Y; Murakawa, Y; Omata, M; Yamashita, T2
Ishiwata, S; Iwase, T; Koizumi, T; Komiyama, N; Komuro, I; Momomura, S; Nakanishi, S; Nishiyama, S; Tanigawa, T1

Reviews

5 review(s) available for nifekalant hydrochloride and Ventricular Fibrillation

ArticleYear
Antiarrhythmic drugs for out-of-hospital cardiac arrest with refractory ventricular fibrillation.
    Critical care (London, England), 2017, Mar-21, Volume: 21, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Emergency Medical Services; Humans; Intensive Care Units; Lidocaine; Out-of-Hospital Cardiac Arrest; Placebos; Pyrimidinones; Ventricular Fibrillation

2017
Meta-analysis of the efficacies of amiodarone and nifekalant in shock-resistant ventricular fibrillation and pulseless ventricular tachycardia.
    Scientific reports, 2017, 10-04, Volume: 7, Issue:1

    Topics: Amiodarone; Humans; Publication Bias; Pulse; Pyrimidinones; Randomized Controlled Trials as Topic; Survival Analysis; Tachycardia, Ventricular; Treatment Outcome; Ventricular Fibrillation

2017
[Drug Therapy for Shock-Resistant Ventricular Fibrillation: Comparison of Nifekalant and Amiodarone].
    Journal of UOEH, 2016, Mar-01, Volume: 38, Issue:1

    Topics: Amiodarone; Anti-Asthmatic Agents; Defibrillators; Humans; Injections, Intravenous; Potassium Channel Blockers; Pyrimidinones; Ventricular Fibrillation

2016
[Management of lethal ventricular arrhythmias after cardiac surgery].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60, Issue:7

    Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Catheter Ablation; Humans; Intra-Aortic Balloon Pumping; Postoperative Complications; Pyrimidinones; Recurrence; Tachycardia, Ventricular; Ventricular Fibrillation

2002
[Strategy for cardiac arrhythmias in acute coronary syndrome].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64, Issue:4

    Topics: Amiodarone; Angina, Unstable; Anti-Asthmatic Agents; Aprindine; Atrial Fibrillation; Bepridil; Electric Countershock; Humans; Myocardial Infarction; Potassium Channel Blockers; Pyrimidinones; Recurrence; Syndrome; Tachycardia, Ventricular; Ventricular Fibrillation

2006

Trials

4 trial(s) available for nifekalant hydrochloride and Ventricular Fibrillation

ArticleYear
The effects of nifekalant hydrochloride on the QT dispersion after direct-current defibrillation.
    Osaka city medical journal, 2008, Volume: 54, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Defibrillators, Implantable; Electrocardiography; Female; Humans; Male; Middle Aged; Pyrimidinones; Sotalol; Tachycardia, Ventricular; Ventricular Fibrillation; Ventricular Function, Left

2008
Effects of intravenous nifekalant as a lifesaving drug for severe ventricular tachyarrhythmias complicating acute coronary syndrome.
    Circulation journal : official journal of the Japanese Circulation Society, 2009, Volume: 73, Issue:11

    Topics: Acute Coronary Syndrome; Aged; Amiodarone; Anti-Arrhythmia Agents; Blood Pressure; Electrocardiography; Emergency Medical Services; Female; Heart Rate; Humans; Infusions, Intravenous; Injections, Intravenous; Lidocaine; Male; Middle Aged; Pyrimidinones; Tachycardia, Ventricular; Torsades de Pointes; Ventricular Fibrillation

2009
Comparative study of nifekalant versus amiodarone for shock-resistant ventricular fibrillation in out-of-hospital cardiopulmonary arrest patients.
    Journal of cardiovascular pharmacology, 2010, Volume: 55, Issue:4

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Drug Therapy, Combination; Electric Countershock; Emergency Service, Hospital; Female; Heart Arrest; Heart Diseases; Humans; Male; Middle Aged; Prognosis; Pyrimidinones; Survival Analysis; Treatment Outcome; Ventricular Fibrillation

2010
Prevention of life-threatening ventricular tachyarrhythmia by a novel and pure class-III agent, nifekalant hydrochloride.
    Journal of cardiovascular pharmacology, 2006, Volume: 48, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Diseases; Humans; Infusions, Intravenous; Male; Middle Aged; Pyrimidinones; Risk Factors; Treatment Outcome; Ventricular Fibrillation

2006

Other Studies

22 other study(ies) available for nifekalant hydrochloride and Ventricular Fibrillation

ArticleYear
"Nonsignificant" early repolarization pattern on postresuscitation ECG as a harbinger of impending electrical storm.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2020, Volume: 25, Issue:3

    Topics: Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Defibrillators, Implantable; Electric Countershock; Electrocardiography; Heart Arrest; Humans; Isosorbide Dinitrate; Magnesium; Male; Middle Aged; Potassium Chloride; Pyrimidinones; Vasodilator Agents; Ventricular Fibrillation

2020
Comparison of nifekalant and amiodarone for resuscitation of out-of-hospital cardiopulmonary arrest resulting from shock-resistant ventricular fibrillation.
    Journal of anesthesia, 2014, Volume: 28, Issue:4

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Dose-Response Relationship, Drug; Electric Countershock; Female; Humans; Male; Middle Aged; Out-of-Hospital Cardiac Arrest; Prospective Studies; Pyrimidinones; Retrospective Studies; Ventricular Fibrillation

2014
Nifekalant Versus Amiodarone in the Treatment of Cardiac Arrest: an Experimental Study in a Swine Model of Prolonged Ventricular Fibrillation.
    Cardiovascular drugs and therapy, 2015, Volume: 29, Issue:5

    Topics: Amiodarone; Animals; Blood Pressure; Cardiopulmonary Resuscitation; Disease Models, Animal; Electric Countershock; Epinephrine; Female; Heart Arrest; Heart Rate; Pyrimidinones; Survival Analysis; Swine; Ventricular Fibrillation

2015
Amiodarone or nifekalant upon hospital arrival for refractory ventricular fibrillation after out-of-hospital cardiac arrest.
    Resuscitation, 2016, Volume: 109

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Emergency Medical Services; Female; Hospital Mortality; Hospitalization; Humans; Male; Middle Aged; Out-of-Hospital Cardiac Arrest; Pyrimidinones; Retrospective Studies; Ventricular Fibrillation; Young Adult

2016
Nifekalant versus lidocaine for in-hospital shock-resistant ventricular fibrillation or tachycardia.
    Resuscitation, 2010, Volume: 81, Issue:1

    Topics: Aged; Anti-Arrhythmia Agents; Chi-Square Distribution; Female; Humans; Lidocaine; Male; Middle Aged; Prospective Studies; Pyrimidinones; Statistics, Nonparametric; Survival Rate; Tachycardia, Ventricular; Treatment Outcome; Ventricular Fibrillation

2010
Comparison of the efficacy of nifekalant and amiodarone in a porcine model of cardiac arrest.
    Resuscitation, 2010, Volume: 81, Issue:8

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Arrest; Heart Rate; Male; Pyrimidinones; Swine; Treatment Outcome; Ventricular Fibrillation; Ventricular Function

2010
Report from J-PULSE multicenter registry of patients with shock-resistant out-of-hospital cardiac arrest treated with nifekalant hydrochloride.
    Circulation journal : official journal of the Japanese Circulation Society, 2010, Volume: 74, Issue:11

    Topics: Aged; Anti-Arrhythmia Agents; Defibrillators; Electric Countershock; Electrocardiography; Feasibility Studies; Female; Humans; Japan; Male; Middle Aged; Out-of-Hospital Cardiac Arrest; Patient Admission; Pilot Projects; Prospective Studies; Pyrimidinones; Registries; Survival Analysis; Survival Rate; Time Factors; Torsades de Pointes; Treatment Failure; Ventricular Fibrillation

2010
Nifekalant hydrochloride for patients with cardiac arrest caused by shockable rhythm.
    Circulation journal : official journal of the Japanese Circulation Society, 2010, Volume: 74, Issue:11

    Topics: Anti-Arrhythmia Agents; Defibrillators; Electric Countershock; Humans; Out-of-Hospital Cardiac Arrest; Patient Admission; Pyrimidinones; Survival Rate; Tachycardia, Ventricular; Time Factors; Torsades de Pointes; Treatment Failure; Ventricular Fibrillation

2010
[Efficacy of Nifekalant hydrochloride for life-threatening ventricular tachyarrhythmias in patients with resistance to lidocaine: a study of patients with out-of-hospital cardiac arrest].
    Journal of cardiology, 2003, Volume: 41, Issue:3

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Drug Resistance; Emergency Medical Services; Epinephrine; Female; Heart Arrest; Humans; Lidocaine; Male; Middle Aged; Prospective Studies; Pyrimidinones; Tachycardia, Ventricular; Ventricular Fibrillation

2003
Defibrillation effects of intravenous nifekalant in patients with out-of-hospital ventricular fibrillation.
    Pacing and clinical electrophysiology : PACE, 2005, Volume: 28 Suppl 1

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Electric Countershock; Emergency Treatment; Female; Humans; Injections, Intravenous; Male; Middle Aged; Pyrimidinones; Ventricular Fibrillation

2005
Efficacy of nifekalant hydrochloride in the treatment of fatal ventricular arrhythmia in patients with ischemic heart disease.
    International heart journal, 2005, Volume: 46, Issue:4

    Topics: Aged; Anti-Arrhythmia Agents; Drug Administration Schedule; Electrocardiography; Female; Humans; Male; Multivariate Analysis; Myocardial Ischemia; Prognosis; Pyrimidinones; Survival Rate; Tachycardia, Ventricular; Ventricular Fibrillation

2005
Emergency treatment with nifekalant, a novel class III anti-arrhythmic agent, for life-threatening refractory ventricular tachyarrhythmias: post-marketing special investigation.
    Circulation journal : official journal of the Japanese Circulation Society, 2005, Volume: 69, Issue:10

    Topics: Aged; Anti-Arrhythmia Agents; Emergency Medical Services; Female; Humans; Male; Marketing; Middle Aged; Pyrimidinones; Torsades de Pointes; Ventricular Fibrillation

2005
[Treatment for perioperative arrhythmias with nifekalant hydrochloride].
    Kyobu geka. The Japanese journal of thoracic surgery, 2006, Volume: 59, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Flutter; Cardiac Surgical Procedures; Female; Humans; Male; Middle Aged; Postoperative Complications; Pyrimidinones; Tachycardia, Ventricular; Ventricular Fibrillation

2006
Comparison of nifekalant and lidocaine for the treatment of shock-refractory ventricular fibrillation.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:4

    Topics: Aged; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Epinephrine; Female; Heart Arrest; Humans; Lidocaine; Male; Middle Aged; Multivariate Analysis; Pyrimidinones; Retrospective Studies; Survival Rate; Time Factors; Ventricular Fibrillation

2006
Nifekalant hydrochloride administration during cardiopulmonary resuscitation improves the transmural dispersion of myocardial repolarization: experimental study in a canine model of cardiopulmonary arrest.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:9

    Topics: Animals; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Disease Models, Animal; Dogs; Heart Arrest; Heart Conduction System; Humans; Pyrimidinones; Tachycardia, Ventricular; Ventricular Fibrillation

2006
[Case of intractable ventricula fibrillation by a multicomponent dietary supplement containing ephedra and caffeine overdose].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2007, Volume: 20, Issue:3

    Topics: Adult; Caffeine; Dietary Supplements; Drug Overdose; Drug Synergism; Electric Countershock; Ephedra; Female; Humans; Hypokalemia; Lidocaine; Magnesium; Pyrimidinones; Ventricular Fibrillation

2007
Effects of the new class III antiarrhythmic drug MS-551 and d-sotalol on canine coronary ligation-reperfusion ventricular arrhythmias.
    Japanese journal of pharmacology, 1995, Volume: 68, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Dogs; Female; Halothane; Ligation; Male; Myocardial Reperfusion; Pentobarbital; Pyrimidinones; Sotalol; Ventricular Fibrillation

1995
Antiarrhythmic agent, MS-551, protects against pinacidil + hypoxia-induced ventricular fibrillation in Langendorff-perfused rabbit isolated heart.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Dogs; Guanidines; Heart; Heart Atria; Hypoxia; In Vitro Techniques; Pinacidil; Pyrimidinones; Rabbits; Vasodilator Agents; Ventricular Fibrillation

1994
MS-551 protects against ventricular fibrillation in a chronic canine model of sudden cardiac death.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Death, Sudden, Cardiac; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Electrocardiography; Electrophysiology; Male; Myocardial Infarction; Pyrimidinones; Random Allocation; Ventricular Fibrillation

1995
Can a class III antiarrhythmic drug improve electrical defibrillation efficacy during ventricular fibrillation?
    Journal of the American College of Cardiology, 1997, Mar-01, Volume: 29, Issue:3

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Dogs; Electric Countershock; Heart; Pyrimidinones; Treatment Outcome; Ventricular Fibrillation

1997
Effect of a class III antiarrhythmic drug on the configuration of dose response curve for defibrillation.
    Pacing and clinical electrophysiology : PACE, 1999, Volume: 22, Issue:3

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Dogs; Electric Countershock; Electrocardiography; Electrophysiology; Pyrimidinones; Ventricular Fibrillation

1999
Efficacy of nifekalant hydrochloride on the treatment of life-threatening ventricular tachyarrhythmias during reperfusion for acute myocardial infarction.
    Cardiovascular drugs and therapy, 2001, Volume: 15, Issue:4

    Topics: Angioplasty, Balloon, Coronary; Anti-Arrhythmia Agents; Coronary Angiography; Electric Countershock; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion; Pyrimidinones; Stents; Ventricular Fibrillation

2001