Page last updated: 2024-11-01

nifedipine and Vitamin D Deficiency

nifedipine has been researched along with Vitamin D Deficiency in 6 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Vitamin D Deficiency: A nutritional condition produced by a deficiency of VITAMIN D in the diet, insufficient production of vitamin D in the skin, inadequate absorption of vitamin D from the diet, or abnormal conversion of vitamin D to its bioactive metabolites. It is manifested clinically as RICKETS in children and OSTEOMALACIA in adults. (From Cecil Textbook of Medicine, 19th ed, p1406)

Research Excerpts

ExcerptRelevanceReference
"Hypertension was not observed in rats fed with a vitamin D-deficient diet or treated with streptozotocin."1.28[Pharmacological study on blood pressure in rats with bone disorders]. ( Shamoto, T, 1989)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Billaudel, BJ1
Bourlon, PM1
Sutter, BC1
Faure-Dussert, AG1
de Boland, AR3
Nemere, I1
Norman, AW1
Norman, A1
Favus, MJ1
Angeid-Backman, E1
Boland, RL1
Shamoto, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase II Study of Oral Calcitriol in Combination With Ketoconazole in Castration Resistant Prostate Cancer, Progressing Despite Primary ADT and Abiraterone[NCT03261336]Phase 21 participants (Actual)Interventional2017-01-06Terminated (stopped due to can not meet enrollment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Toxicity and Tolerability of Experimental Arm

Descriptive analysis of observed toxicity and patient reports of tolerating experimental treatment (NCT03261336)
Timeframe: 2 years

InterventionParticipants (Count of Participants)
Calcitriol, Ketoconazole, Hydrocortisone1

Other Studies

6 other studies available for nifedipine and Vitamin D Deficiency

ArticleYear
Regulatory effect of 1,25-dihydroxyvitamin D3 on insulin release and calcium handling via the phospholipid pathway in islets from vitamin D-deficient rats.
    Journal of endocrinological investigation, 1995, Volume: 18, Issue:9

    Topics: Acetylcholine; Animals; Calcitriol; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Glucos

1995
Ca2(+)-channel agonist BAY K8644 mimics 1,25(OH)2-vitamin D3 rapid enhancement of Ca2+ transport in chick perfused duodenum.
    Biochemical and biophysical research communications, 1990, Jan-15, Volume: 166, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Evidence for involvement of protein kinase C and cyclic adenosine 3',5' monophosphate-dependent protein kinase in the 1,25-dihydroxy-vitamin D3-mediated rapid stimulation of intestinal calcium transport, (transcaltachia).
    Endocrinology, 1990, Volume: 127, Issue:1

    Topics: Alkaloids; Animals; Biological Transport; Calcitriol; Calcium; Chickens; Colforsin; Cyclic AMP; Duod

1990
Effects of 1,25(OH)2D3 and calcium channel blockers on cecal calcium transport in the rat.
    The American journal of physiology, 1985, Volume: 248, Issue:6 Pt 1

    Topics: Animals; Biological Transport, Active; Calcitriol; Calcium; Calcium Channel Blockers; Cecum; Intesti

1985
Rapid changes in skeletal muscle calcium uptake induced in vitro by 1,25-dihydroxyvitamin D3 are suppressed by calcium channel blockers.
    Endocrinology, 1987, Volume: 120, Issue:5

    Topics: Animals; Calcitriol; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cell Membrane; Chicke

1987
[Pharmacological study on blood pressure in rats with bone disorders].
    Aichi Gakuin Daigaku Shigakkai shi, 1989, Volume: 27, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bone Dis

1989