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nifedipine and Ventricular Fibrillation

nifedipine has been researched along with Ventricular Fibrillation in 35 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.

Research Excerpts

ExcerptRelevanceReference
" Therefore, this study was aimed to investigate the effects of mebudipine on myocardial arrhythmias and tissue injury induced by ischemia/reperfusion injury in isolated rat hearts."7.83The effects of mebudipine on myocardial arrhythmia induced by ischemia-reperfusion injury in isolated rat heart. ( Badalzadeh, R; Ghiasi, A; Ghiasi, R; Majidinia, M; Mohammadi, M; Yousefi, B, 2016)
"To relate the evolution of ventricular fibrillation (VF) to the haemodynamic recovery after cardioversion, we characterized the differences in the ECG power spectrum (PS) time course, among different types of VF: under control conditions, with previous administration of nifedipine and on cardiopulmonary bypass (CPB)."7.67Relation between power spectrum time course during ventricular fibrillation and electromechanical dissociation. Effects of coronary perfusion and nifedipine. ( Cosin, J; Hernandez, A; Llamas, P; Martin, G; Such, M, 1986)
"The effect of aprindine, verapamil and nifedipine on electrical stimulation threshold (EST) and ventricular fibrillation threshold (VFT) was studied in isolated rabbit hearts."7.67Effect of aprindine, verapamil and nifedipine on ventricular fibrillation threshold in isolated rabbit hearts. ( Almotrefi, AA, 1985)
"A 10 min ligation of the left anterior descending coronary artery in anaesthetized pigs resulted in ventricular fibrillation (VF) in 70% of control and propranolol-treated animals."7.66The effect of felodipine on ventricular fibrillation after coronary artery ligation in the anaesthetized pig. ( Verdouw, PD; Wolffenbuttel, BH, 1983)
"It is reported that nifedipine, a newly developed antianginal agent, was dramatically effective to suppress the repeatedly occurring ventricular fibrillation in 2 cases of variant form of angina pectoris."7.65Suppression of repeatedly occurring ventricular fibrillation with nifedipine in variant form of angina pectoris. ( Hashimoto, H; Honda, Y; Kimura, E; Mizuno, K; Tanaka, K, 1977)
"Before cardiac arrest, 10 animals were randomly assigned to receive either nifedipine (0."5.32The effects of nifedipine on ventricular fibrillation mean frequency in a porcine model of prolonged cardiopulmonary resuscitation. ( Amann, A; Augenstein, S; Krismer, AC; Lindner, KH; Raedler, C; Rheinberger, K; Stadlbauer, KH; Strohmenger, HU; Voelckel, WG; Wagner-Berger, HG; Wenzel, V, 2003)
"The number of reperfusion arrhythmias was also significantly lower in the treated animals."5.27Nifedipine with and without propranolol in the treatment of myocardial ischemia: effect on ventricular arrhythmias and recovery of regional wall function. ( ten Cate, FJ; Verdouw, PD; Wolffenbuttel, BH, 1983)
" In experimental animals, verapamil has been shown to reduce vulnerability to ventricular fibrillation during sympathetic stimulation and to prevent spontaneous fibrillation during both myocardial ischaemia and reperfusion."4.77Mechanisms involved in reperfusion arrhythmias. ( Hagestad, EL; Verrier, RL, 1986)
" Therefore, this study was aimed to investigate the effects of mebudipine on myocardial arrhythmias and tissue injury induced by ischemia/reperfusion injury in isolated rat hearts."3.83The effects of mebudipine on myocardial arrhythmia induced by ischemia-reperfusion injury in isolated rat heart. ( Badalzadeh, R; Ghiasi, A; Ghiasi, R; Majidinia, M; Mohammadi, M; Yousefi, B, 2016)
"The ability of the two calcium-antagonists Verapamil and Nifedipine to reduce ventricular electrical instability following acute transient coronary artery occlusion and release and to prevent ventricular arrhythmias, particularly fibrillation, was evaluated on a total of 25 anaesthetized and artificially ventilated dogs."3.67[Comparative studies on the anti-arrhythmic and anti-fibrillatory effectiveness of verapamil and nifedipine following acute coronary artery occlusion and reperfusion]. ( Bender, F; Brisse, B; Gülker, H; Thale, J, 1984)
"The effects of three calcium antagonists (diltiazem, verapamil, and nifedipine) on reperfusion-induced arrhythmias were compared in a conscious rat preparation with coronary artery occlusion and implanted electrocardiogram limb electrodes."3.67Reperfusion-induced arrhythmias in the conscious rat: a comparative study with three calcium antagonists. ( Braimbridge, MV; Hearse, DJ; Kinoshita, K; Manning, AS; Mitani, A, 1989)
"A 10 min ligation of the left anterior descending coronary artery in anaesthetized pigs resulted in ventricular fibrillation (VF) in 70% of control and propranolol-treated animals."3.66The effect of felodipine on ventricular fibrillation after coronary artery ligation in the anaesthetized pig. ( Verdouw, PD; Wolffenbuttel, BH, 1983)
"The intravenous administration of either nifedipine (in doses of 5-50 microgram/kg), or nisoldipine (5-1000 microgram/kg) markedly reduced, or abolished, the serious ventricular arrhythmias (tachycardia and fibrillation) that result from acute coronary artery artery ligation in pentobarbitone-anaesthetized rats."3.66Calcium antagonists prevent early post-infarction ventricular fibrillation. ( Fagbemi, O; Parratt, JR, 1981)
"It is reported that nifedipine, a newly developed antianginal agent, was dramatically effective to suppress the repeatedly occurring ventricular fibrillation in 2 cases of variant form of angina pectoris."3.65Suppression of repeatedly occurring ventricular fibrillation with nifedipine in variant form of angina pectoris. ( Hashimoto, H; Honda, Y; Kimura, E; Mizuno, K; Tanaka, K, 1977)
"Before cardiac arrest, 10 animals were randomly assigned to receive either nifedipine (0."1.32The effects of nifedipine on ventricular fibrillation mean frequency in a porcine model of prolonged cardiopulmonary resuscitation. ( Amann, A; Augenstein, S; Krismer, AC; Lindner, KH; Raedler, C; Rheinberger, K; Stadlbauer, KH; Strohmenger, HU; Voelckel, WG; Wagner-Berger, HG; Wenzel, V, 2003)
"Ventricular fibrillation was induced in 35 closed-chest dogs."1.28Effect of calcium channel blockers on hemodynamic responses to defibrillation. ( Fox-Eastham, K; Hite, PR; Kerber, RE; Kieso, RA; Schröder, E, 1989)
"Twenty-six patients had no ventricular arrhythmias in 633 ischemic attacks; 16 patients had ventricular arrhythmias in 116/586 ischemic attacks."1.27[Characterization and therapy of ventricular arrhythmias due to transient myocardial ischemic attacks in variant angina]. ( Dini, P; Prati, PL; Rocca, P; Turitto, G; Vicari, M; Zanchi, E, 1984)
"The number of reperfusion arrhythmias was also significantly lower in the treated animals."1.27Nifedipine with and without propranolol in the treatment of myocardial ischemia: effect on ventricular arrhythmias and recovery of regional wall function. ( ten Cate, FJ; Verdouw, PD; Wolffenbuttel, BH, 1983)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199026 (74.29)18.7374
1990's5 (14.29)18.2507
2000's3 (8.57)29.6817
2010's1 (2.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ghiasi, R1
Mohammadi, M1
Majidinia, M1
Yousefi, B1
Ghiasi, A1
Badalzadeh, R1
Choi, BR1
Nho, W1
Liu, T1
Salama, G1
Stadlbauer, KH1
Rheinberger, K1
Wenzel, V1
Raedler, C1
Krismer, AC1
Strohmenger, HU1
Augenstein, S1
Wagner-Berger, HG1
Voelckel, WG1
Lindner, KH1
Amann, A1
Ziacchi, V1
Rossi, A1
Lomanto, B1
Opie, LH1
Thandroyen, FT2
Hamm, CW1
Muller, CA1
Lloyd, EA1
Gordon, D1
Zipes, DP1
Gilmour, RF1
Gülker, H1
Thale, J1
Brisse, B1
Bender, F1
Turitto, G1
Dini, P1
Rocca, P1
Vicari, M1
Zanchi, E1
Prati, PL1
Perez-Olea, J1
Quevedo, M1
Verdouw, PD2
Wolffenbuttel, BH2
ten Cate, FJ1
Peter, T1
Fujimoto, T1
Hamamoto, H1
Mandel, WJ1
Kimura, E2
Tanaka, K2
Mizuno, K2
Honda, Y2
Hashimoto, H2
Lubbe, WF1
McLean, JA1
Nguyen, T1
Sheehan, FH1
Epstein, SE1
Ribeiro, LG2
De Bauche, TL1
Brandon, TA2
Maroko, PR2
Miller, RR2
Hess, OM1
Graf, C1
Frey, R1
Dettli, R1
Siegenthaler, W1
Fagbemi, O1
Parratt, JR1
DeBauche, TL1
Weston, CF1
Tigg, A1
Griffiths, BE1
Roine, RO1
Vara, J1
Alvarez, G1
Lambert, JL1
Espolita, A1
Rubín, JM1
Posada, IS1
Cortina, A1
Morís, C1
Hayashi, Y1
Tajima, K1
Kirimoto, T1
Miyake, H1
Matsuura, N1
Kreuzer, J1
von Hodenberg, E1
Jahn, L1
Kübler, W1
Behar, S1
Goldbourt, U1
Reicher-Reiss, H1
Kaplinsky, E1
Billman, GE1
Kinoshita, K1
Mitani, A1
Hearse, DJ1
Braimbridge, MV1
Manning, AS1
Hite, PR1
Schröder, E1
Kieso, RA1
Fox-Eastham, K1
Kerber, RE1
Priori, SG1
Zuanetti, G1
Schwartz, PJ1
Verrier, RL1
Hagestad, EL1
Martin, G1
Cosin, J1
Such, M1
Hernandez, A1
Llamas, P1
Schwartz, A1
Matlib, MA1
Balwierczak, J1
Lathrop, DA1
Almotrefi, AA1

Reviews

4 reviews available for nifedipine and Ventricular Fibrillation

ArticleYear
Calcium antagonists and the acutely ischemic heart: experimental effects on ventricular fibrillation and enzyme release.
    European heart journal, 1983, Volume: 4 Suppl C

    Topics: Adrenergic beta-Antagonists; Animals; Calcium; Calcium Channel Blockers; Humans; L-Lactate Dehydroge

1983
Calcium antagonists and their potential role in the prevention of sudden coronary death.
    Annals of the New York Academy of Sciences, 1982, Volume: 382

    Topics: Action Potentials; Animals; Atrial Fibrillation; Atrial Flutter; Atrioventricular Node; Calcium Chan

1982
Pre-hospital cardiac arrest associated with coronary artery spasm.
    International journal of cardiology, 1993, Volume: 38, Issue:1

    Topics: Adult; Cardiac Catheterization; Coronary Angiography; Coronary Vasospasm; Echocardiography; Ergonovi

1993
Mechanisms involved in reperfusion arrhythmias.
    European heart journal, 1986, Volume: 7 Suppl A

    Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Dil

1986

Trials

1 trial available for nifedipine and Ventricular Fibrillation

ArticleYear
Prognosis of acute myocardial infarction complicated by primary ventricular fibrillation. Principal Investigators of the SPRINT Study.
    The American journal of cardiology, 1990, Nov-15, Volume: 66, Issue:17

    Topics: Aged; Female; Humans; Incidence; Israel; Male; Middle Aged; Myocardial Infarction; Nifedipine; Progn

1990

Other Studies

30 other studies available for nifedipine and Ventricular Fibrillation

ArticleYear
The effects of mebudipine on myocardial arrhythmia induced by ischemia-reperfusion injury in isolated rat heart.
    Cellular and molecular biology (Noisy-le-Grand, France), 2016, Nov-30, Volume: 62, Issue:13

    Topics: Animals; Arrhythmias, Cardiac; Creatine Kinase; Heart; Heart Rate; In Vitro Techniques; L-Lactate De

2016
Life span of ventricular fibrillation frequencies.
    Circulation research, 2002, Aug-23, Volume: 91, Issue:4

    Topics: Action Potentials; Algorithms; Animals; Biological Clocks; Calcium Channel Blockers; Calcium Channel

2002
The effects of nifedipine on ventricular fibrillation mean frequency in a porcine model of prolonged cardiopulmonary resuscitation.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:1

    Topics: Animals; Calcium Channel Blockers; Cardiopulmonary Resuscitation; Coronary Circulation; Electrocardi

2003
[Nifedipine in the therapy of myocardial infarct in patients over 70].
    Minerva cardioangiologica, 1982, Volume: 30, Issue:4

    Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Digitalis Glycosides; Female; Heart Block

1982
Protective action of calcium channel antagonist agents against ventricular fibrillation in the isolated perfused rat heart.
    Journal of molecular and cellular cardiology, 1982, Volume: 14, Issue:1

    Topics: Adenine Nucleotides; Animals; Calcium; Coronary Circulation; Coronary Disease; Cyclic AMP; Diltiazem

1982
[Comparative studies on the anti-arrhythmic and anti-fibrillatory effectiveness of verapamil and nifedipine following acute coronary artery occlusion and reperfusion].
    Zeitschrift fur Kardiologie, 1984, Volume: 73, Issue:8

    Topics: Animals; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Coronary Circulation; Dogs; Electrocardio

1984
[Characterization and therapy of ventricular arrhythmias due to transient myocardial ischemic attacks in variant angina].
    Giornale italiano di cardiologia, 1984, Volume: 14, Issue:9

    Topics: Adult; Aged; Angina Pectoris, Variant; Arrhythmias, Cardiac; Coronary Disease; Electrocardiography;

1984
Protective effect of nifedipine upon digitalis intoxication.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:10

    Topics: Animals; Blood Pressure; Cats; Digitalis Glycosides; Electrocardiography; Female; Heart Rate; Lanato

1984
Nifedipine with and without propranolol in the treatment of myocardial ischemia: effect on ventricular arrhythmias and recovery of regional wall function.
    European heart journal, 1983, Volume: 4 Suppl C

    Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Heart; Myocardium; Nifedipine; Propranolol; Swine;

1983
Comparative study of the effect of slow channel inhibiting agents on ischemia-induced conduction delay as relevant to the genesis of ventricular fibrillation.
    American heart journal, 1983, Volume: 106, Issue:5 Pt 1

    Topics: Animals; Calcium Channel Blockers; Coronary Disease; Diltiazem; Dogs; Heart; Heart Conduction System

1983
Suppression of repeatedly occurring ventricular fibrillation with nifedipine in variant form of angina pectoris.
    British journal of clinical practice. Supplement, 1980, Volume: 8

    Topics: Aged; Angina Pectoris; Angina Pectoris, Variant; Humans; Male; Middle Aged; Nifedipine; Pyridines; V

1980
Antiarrhythmic actions of nifedipine in acute myocardial ischemia.
    American heart journal, 1983, Volume: 105, Issue:2

    Topics: Animals; Coronary Circulation; Coronary Disease; Heart Rate; Male; Myocardium; Nifedipine; Pyridines

1983
The effect of felodipine on ventricular fibrillation after coronary artery ligation in the anaesthetized pig.
    British journal of pharmacology, 1983, Volume: 79, Issue:1

    Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiac Output; Coronary Vessels; Felod

1983
Effects of calcium channel blocking agents on reperfusion arrhythmias.
    American heart journal, 1982, Volume: 103, Issue:6

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dogs; Female; He

1982
[Ventricular arrhythmias following coronary reperfusion. Comparative study of the effects of verapamil and nifedipine].
    Arquivos brasileiros de cardiologia, 1982, Volume: 38, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Coronary Circulation; Dogs; Female; Hemodynamics; Male; Microspheres;

1982
[Coronary artery spasms with normal coronary arteries as the cause of recurrent ventricular fibrillations].
    Schweizerische medizinische Wochenschrift, 1981, May-23, Volume: 111, Issue:21

    Topics: Angina Pectoris; Angina Pectoris, Variant; Coronary Angiography; Electrocardiography; Humans; Male;

1981
Calcium antagonists prevent early post-infarction ventricular fibrillation.
    European journal of pharmacology, 1981, Nov-05, Volume: 75, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Hemodynamics; Male; Myocardial Infarction;

1981
Comparative effects of verapamil and nifedipine on reactive hyperemia and ventricular arrhythmias during coronary artery reperfusion.
    European heart journal, 1980, Volume: 1, Issue:Suppl B

    Topics: Animals; Arrhythmias, Cardiac; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Femal

1980
Nimodipine in patients with heart disease.
    Circulation, 1996, Apr-01, Volume: 93, Issue:7

    Topics: Antihypertensive Agents; Calcium Channel Blockers; Cerebrovascular Disorders; Clinical Trials as Top

1996
[Coronary spasm and heart arrest caused by ventricular fibrillation].
    Revista espanola de cardiologia, 1998, Volume: 51, Issue:5

    Topics: Adult; Calcium Channel Blockers; Coronary Angiography; Coronary Vasospasm; Electrocardiography, Ambu

1998
Cardioprotective effects of MET-88, a gamma-butyrobetaine hydroxylase inhibitor, on cardiac dysfunction induced by ischemia/reperfusion in isolated rat hearts.
    Pharmacology, 2000, Volume: 61, Issue:4

    Topics: Animals; Carnitine; Enzyme Inhibitors; gamma-Butyrobetaine Dioxygenase; Heart Function Tests; Hemody

2000
Suppression of repeatedly occurring ventricular fibrillation with nifedipine in variant form of angina pectoris.
    Japanese heart journal, 1977, Volume: 18, Issue:5

    Topics: Aged; Angina Pectoris; Angina Pectoris, Variant; Humans; Male; Middle Aged; Nifedipine; Pyridines; V

1977
[Recurrent ventricular fibrillation in a patient with angiographically normal coronary arteries and intermittent ST segment elevation].
    Zeitschrift fur Kardiologie, 1990, Volume: 79, Issue:8

    Topics: Adult; Angina Pectoris; Angiocardiography; Drug Therapy, Combination; Electrocardiography; Humans; M

1990
Effect of calcium channel antagonists on susceptibility to sudden cardiac death: protection from ventricular fibrillation.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Reperfusion-induced arrhythmias in the conscious rat: a comparative study with three calcium antagonists.
    The Journal of surgical research, 1989, Volume: 47, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Consciousness; Coronary Disease; Diltiazem; Electrocardiography; Hear

1989
Effect of calcium channel blockers on hemodynamic responses to defibrillation.
    American heart journal, 1989, Volume: 117, Issue:3

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Pacing, Artificial; Diltiazem; Dogs; Elec

1989
Ventricular fibrillation induced by the interaction between acute myocardial ischemia and sympathetic hyperactivity: effect of nifedipine.
    American heart journal, 1988, Volume: 116, Issue:1 Pt 1

    Topics: Acute Disease; Animals; Cardiac Pacing, Artificial; Cats; Coronary Disease; Disease Models, Animal;

1988
Relation between power spectrum time course during ventricular fibrillation and electromechanical dissociation. Effects of coronary perfusion and nifedipine.
    European heart journal, 1986, Volume: 7, Issue:7

    Topics: Animals; Cardiopulmonary Bypass; Dogs; Electric Countershock; Electrocardiography; Electrophysiology

1986
Pharmacology of calcium antagonists.
    The American journal of cardiology, 1985, Mar-15, Volume: 55, Issue:7

    Topics: Action Potentials; Animals; Atrioventricular Node; Bepridil; Calcium Channel Blockers; Coronary Vess

1985
Effect of aprindine, verapamil and nifedipine on ventricular fibrillation threshold in isolated rabbit hearts.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 274, Issue:1

    Topics: Animals; Aprindine; Calcium Channel Blockers; Electric Stimulation; Female; Heart Rate; In Vitro Tec

1985