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nifedipine and Vascular Diseases

nifedipine has been researched along with Vascular Diseases in 19 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Vascular Diseases: Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.

Research Excerpts

ExcerptRelevanceReference
"Nifedipine antagonises influx of calcium through cell membrane slow channels, and sustained release formulations of the calcium channel blocker have been shown to be effective in the treatment of mild to moderate hypertension and both stable and variant angina pectoris."8.78Sustained release nifedipine formulations. An appraisal of their current uses and prospective roles in the treatment of hypertension, ischaemic heart disease and peripheral vascular disorders. ( Brogden, RN; Murdoch, D, 1991)
"To explore the effects and related mechanism of nifedipine on vascular inflammation induced by cuff placement."7.76[Nifedipine attenuates vascular inflammation via inhibin NF-κB activity]. ( Gao, XY; Liu, SK; Lu, FQ; Yu, Q; Zhang, ST; Zhou, SM, 2010)
" We, along with others, have recently found that nifedipine, one of the most widely used DHPs, inhibits apoptotic cell death of endothelial cells (ECs) as well as vascular inflammation and subsequently improves endothelial function in patients with cardiovascular risk factors, including hypertension and/or diabetes, thus slowing the development and progression of atherosclerosis in these patients."4.84Role of oxidative stress in the development of vascular injury and its therapeutic intervention by nifedipine. ( Matsui, T; Nakamura, K; Yamagishi, S, 2008)
"Nifedipine antagonises influx of calcium through cell membrane slow channels, and sustained release formulations of the calcium channel blocker have been shown to be effective in the treatment of mild to moderate hypertension and both stable and variant angina pectoris."4.78Sustained release nifedipine formulations. An appraisal of their current uses and prospective roles in the treatment of hypertension, ischaemic heart disease and peripheral vascular disorders. ( Brogden, RN; Murdoch, D, 1991)
"To explore the effects and related mechanism of nifedipine on vascular inflammation induced by cuff placement."3.76[Nifedipine attenuates vascular inflammation via inhibin NF-κB activity]. ( Gao, XY; Liu, SK; Lu, FQ; Yu, Q; Zhang, ST; Zhou, SM, 2010)
"Breast pain is a common complaint among lactating women."1.33Vasospasm of the nipple presenting as painful lactation. ( McKenna, DS; Page, SM, 2006)
"Treatment with nifedipine did not significantly change any of the pulmonary function values, except for the carbon monoxide diffusing capacity (DLCO)."1.28Diffusing capacity of the lung and nifedipine in systemic sclerosis. ( Georgiakodis, F; Kyriakidis, M; Papazoglou, S; Sfikakis, P; Sfikakis, PP; Toutouzas, P; Vergos, C, 1990)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199012 (63.16)18.7374
1990's2 (10.53)18.2507
2000's4 (21.05)29.6817
2010's1 (5.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, XY1
Yu, Q1
Liu, SK1
Lu, FQ1
Zhou, SM1
Zhang, ST1
Garrison, CP1
Yamasaki, K1
Aoki, M1
Makino, H1
Hashiya, N1
Shimizu, H1
Ohishi, M1
Ogihara, T1
Morishita, R1
Page, SM1
McKenna, DS1
Yamagishi, S1
Nakamura, K1
Matsui, T1
Luckhaus, G2
Garthoff, B2
Kazda, S2
Hodara, M1
Strano, A1
Novo, S1
Cornacchia, D1
Finzi, CM1
Marchi, G1
Murdoch, D1
Brogden, RN1
Sfikakis, PP1
Kyriakidis, M1
Vergos, C1
Papazoglou, S1
Georgiakodis, F1
Toutouzas, P1
Sfikakis, P1
Becker, GJ1
Katzen, BT1
Dake, MD1
Belcaro, G1
Nicholaides, AN1
Shub, C1
Vlietstra, RE1
McGoon, MD1
Larach, DR1
Zelis, R1
Ahn, YS1
Jy, W1
Harrington, WJ1
Shanbaky, N1
Fernandez, LF1
Haynes, DH1
Barst, RJ1
Stalcup, SA1
Steeg, CN1
Hall, JC1
Frosolono, MF1
Cato, AE1
Mellins, RB1
Teba, L1
Smailer, S1
Taylor, HC1
Nash, G1
Feller, W1

Reviews

6 reviews available for nifedipine and Vascular Diseases

ArticleYear
Role of oxidative stress in the development of vascular injury and its therapeutic intervention by nifedipine.
    Current medicinal chemistry, 2008, Volume: 15, Issue:2

    Topics: Antioxidants; Apoptosis; Atherosclerosis; Calcium Channels; Cardiovascular Diseases; Cytokines; Diab

2008
[Calcium antagonists in cardiology].
    Bollettino della Societa italiana di cardiologia, 1978, Issue:1 Suppl

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arrhythmias, Cardiac; Calcium; Coronary Disease; Human

1978
Sustained release nifedipine formulations. An appraisal of their current uses and prospective roles in the treatment of hypertension, ischaemic heart disease and peripheral vascular disorders.
    Drugs, 1991, Volume: 41, Issue:5

    Topics: Coronary Disease; Delayed-Action Preparations; Drug Combinations; Drug Design; Humans; Hypertension;

1991
Noncoronary angioplasty.
    Radiology, 1989, Volume: 170, Issue:3 Pt 2

    Topics: Angioplasty, Balloon; Aspirin; Constriction, Pathologic; Heparin; Humans; Nifedipine; Nitroglycerin;

1989
Selection of optimal drug therapy for the patient with angina pectoris.
    Mayo Clinic proceedings, 1985, Volume: 60, Issue:8

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arrhythmias, Cardiac; Blood Pressure; Calcium Channel

1985
Advances in calcium blocker therapy.
    American journal of surgery, 1986, Volume: 151, Issue:4

    Topics: Arrhythmias, Cardiac; Arteriosclerosis; Asthma; Blood Platelet Disorders; Calcium; Calcium Channel B

1986

Trials

1 trial available for nifedipine and Vascular Diseases

ArticleYear
Effect of nifedipine on endothelial function in normotensive smokers: potential contribution of increase in circulating hepatocyte growth factor.
    Journal of human hypertension, 2004, Volume: 18, Issue:10

    Topics: Adult; Calcium Channel Blockers; Endothelium, Vascular; Hepatocyte Growth Factor; Humans; Male; Nife

2004

Other Studies

12 other studies available for nifedipine and Vascular Diseases

ArticleYear
[Nifedipine attenuates vascular inflammation via inhibin NF-κB activity].
    Zhonghua xin xue guan bing za zhi, 2010, Volume: 38, Issue:11

    Topics: Animals; Blood Vessels; Chemokine CCL2; Inflammation; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Ni

2010
Nipple vasospasms, Raynaud's syndrome, and nifedipine.
    Journal of human lactation : official journal of International Lactation Consultant Association, 2002, Volume: 18, Issue:4

    Topics: Adult; Female; Humans; Muscle, Smooth, Vascular; Nifedipine; Nipples; Raynaud Disease; Spasm; Vascul

2002
Vasospasm of the nipple presenting as painful lactation.
    Obstetrics and gynecology, 2006, Volume: 108, Issue:3 Pt 2

    Topics: Adult; Breast Feeding; Female; Humans; Lactation; Nifedipine; Nipples; Pain; Raynaud Disease; Vascul

2006
Prevention of hypertensive vasculopathy by nifedipine in salt-loaded Dahl rats.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:11

    Topics: Animals; Blood Pressure; Body Weight; Female; Hematocrit; Hypertension; Nifedipine; Pyridines; Rats;

1982
[Treatment of stage II arteriopathy of the lower limbs with coronary involvement (author's transl)].
    Journal des maladies vasculaires, 1981, Volume: 6, Issue:1

    Topics: Arterial Occlusive Diseases; Arteries; Coronary Disease; Diltiazem; Humans; Leg; Nifedipine; Physica

1981
[Preliminary evaluation of the use of nifedipine in peripheral circulatory disorders on a functional basis].
    Bollettino della Societa italiana di cardiologia, 1978, Volume: 23, Issue:9

    Topics: Adult; Aged; Blood Circulation; Cold Temperature; Drug Evaluation; Female; Humans; Male; Middle Aged

1978
Diffusing capacity of the lung and nifedipine in systemic sclerosis.
    Arthritis and rheumatism, 1990, Volume: 33, Issue:11

    Topics: Adult; Carbon Monoxide; Drug Administration Schedule; Female; Hemodynamics; Humans; Lung Diseases; M

1990
Microvascular evaluation of the effects of nifedipine in vascular patients by laser-Doppler flowmetry.
    Angiology, 1989, Volume: 40, Issue:8

    Topics: Diabetic Angiopathies; Female; Foot; Humans; Lasers; Male; Microcirculation; Middle Aged; Nifedipine

1989
Increased platelet calcium in thrombosis and related disorders and its correction by nifedipine.
    Thrombosis research, 1987, Jan-15, Volume: 45, Issue:2

    Topics: Arteriosclerosis; Blood Platelets; Calcium; Homeostasis; Humans; Nifedipine; Thrombosis; Vascular Di

1987
Relation of arachidonate metabolites to abnormal control of the pulmonary circulation in a child.
    The American review of respiratory disease, 1985, Volume: 131, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Aging; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Diltiazem;

1985
Effect of nifedipine on TRH stimulation of TSH and PRL release by the pituitary gland.
    Metabolism: clinical and experimental, 1985, Volume: 34, Issue:2

    Topics: Adult; Aged; Female; Heart Diseases; Humans; Hypothalamo-Hypophyseal System; Joint Diseases; Male; M

1985
Healing of malignant hypertensive arteriopathy in Dahl rats by nifedipine.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:1

    Topics: Animals; Blood Pressure; Female; Hypertension; Mesenteric Arteries; Nifedipine; Rats; Sodium Chlorid

1985