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nifedipine and Tourette Syndrome

nifedipine has been researched along with Tourette Syndrome in 4 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Tourette Syndrome: A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or another medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)

Research Excerpts

ExcerptRelevanceReference
"A 22-year-old man with severe Tourette syndrome successfully treated with nifedipine is described."7.67A case of Tourette syndrome treated with nifedipine. ( Berg, R, 1985)
"A 22-year-old man with severe Tourette syndrome successfully treated with nifedipine is described."3.67A case of Tourette syndrome treated with nifedipine. ( Berg, R, 1985)
"Six males and one female with chronic tic disorders, whose ages ranged from 12 to 31 years, were evaluated before treatment, after 1 month on placebo, after a single 10 mg nifedipine dose (three patients), and monthly while on flunarizine 10-15 mg (mean dose of 13 mg)."2.67Treatment of Tourette's syndrome with calcium antagonists. ( Casas Parera, I; Fernandez Pardal, M; Gatto, M; Lekhuniec, E; Mangone, C; Micheli, F; Pikielny, R, 1990)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goldstein, JA1
Micheli, F1
Gatto, M1
Lekhuniec, E1
Mangone, C1
Fernandez Pardal, M1
Pikielny, R1
Casas Parera, I1
Alessi, NE1
Walden, M1
Hsieh, PS1
Berg, R1

Trials

1 trial available for nifedipine and Tourette Syndrome

ArticleYear
Treatment of Tourette's syndrome with calcium antagonists.
    Clinical neuropharmacology, 1990, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Calcium Channel Blockers; Female; Flunarizine; Humans; Male; Nifedipine; Tic Diso

1990

Other Studies

3 other studies available for nifedipine and Tourette Syndrome

ArticleYear
Nifedipine treatment of Tourette's syndrome.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:8

    Topics: Child; Humans; Male; Nifedipine; Tourette Syndrome

1984
Nifedipine-haloperidol combination in the treatment of Gilles de la Tourette's syndrome: a case study.
    The Journal of clinical psychiatry, 1989, Volume: 50, Issue:3

    Topics: Administration, Oral; Child; Drug Therapy, Combination; Haloperidol; Humans; Male; Nifedipine; Toure

1989
A case of Tourette syndrome treated with nifedipine.
    Acta psychiatrica Scandinavica, 1985, Volume: 72, Issue:4

    Topics: Adult; Humans; Male; Nifedipine; Obsessive Behavior; Tourette Syndrome

1985