Page last updated: 2024-11-01

nifedipine and Thrombosis

nifedipine has been researched along with Thrombosis in 16 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.

Research Excerpts

ExcerptRelevanceReference
" The aim was to test the efficacy of local application of nifedipine ointment in healing acute thrombosed external hemorrhoids."9.09Conservative treatment of acute thrombosed external hemorrhoids with topical nifedipine. ( Antropoli, C; Antropoli, M; De Stefano, G; Molino, D; Perrotti, P, 2001)
" In the present study, the effects of two calcium blockers, verapamil and nifedipine, were compared in several rodent thrombosis models."7.67Comparison of verapamil and nifedipine in thrombosis models. ( Forman, G; Myers, AK; Penhos, J; Ramwell, P; Torres Duarte, AP, 1986)
" The aim was to test the efficacy of local application of nifedipine ointment in healing acute thrombosed external hemorrhoids."5.09Conservative treatment of acute thrombosed external hemorrhoids with topical nifedipine. ( Antropoli, C; Antropoli, M; De Stefano, G; Molino, D; Perrotti, P, 2001)
"The effects of nifedipine (Nif), aspirin (ASA) and ASA + Nif on platelet aggregation and generation of thrombosis were studied."3.68[Effects of the combination of aspirin and nifedipine on platelet aggregation and thrombogenesis]. ( Dong, E; Shi, S, 1990)
"A series of 1,4-dihydropyridines (DHP) bound to 1,2-benzisothiazol-3-ones were synthesized and evaluated for their ability to inhibit platelet aggregation induced by collagen in human platelet-rich plasma (PRP) and to protect mice against experimental thrombosis."3.67Synthesis, platelet aggregation inhibitory activity, and in vivo antithrombotic activity of new 1,4-dihydropyridines. ( Cillero, FJ; Fau de Casa-Juana, M; Ortega, MP; Priego, JG; Sunkel, CE, 1988)
" In the present study, the effects of two calcium blockers, verapamil and nifedipine, were compared in several rodent thrombosis models."3.67Comparison of verapamil and nifedipine in thrombosis models. ( Forman, G; Myers, AK; Penhos, J; Ramwell, P; Torres Duarte, AP, 1986)
" The dihydropyridine agents, CRE-223 and Nifedipine, were highly protective against experimental thrombosis, whereas Verapamil had a weaker and much shorter effect and, on the other hand, Diltiazem had no protective effect over a range of doses."3.67The antithrombogenic in vivo effects of calcium channel blockers in experimental thrombosis in mice. ( Ortega, MP; Priego, JG; Statkow, PR; Sunkel, C, 1987)
"When the mural thrombus was removed from 14 grafts, a median 73% of the platelets were located in the interface between thrombus and graft."1.27Comparison of the antithrombotic action of calcium antagonist drugs with dipyridamole in dogs. ( Chesebro, JH; Dewanjee, MK; Fuster, V; Kaye, MP; Pumphrey, CW; Vlietstra, RE, 1983)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199010 (62.50)18.7374
1990's4 (25.00)18.2507
2000's2 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sunkel, CE1
Fau de Casa-Juana, M1
Cillero, FJ1
Priego, JG2
Ortega, MP2
Loi, K1
Tan, KT1
Mysliwiec, M1
Rydzewski, A1
Bulhak, W1
Pumphrey, CW1
Fuster, V1
Dewanjee, MK1
Chesebro, JH1
Vlietstra, RE1
Kaye, MP1
Klaus, AP1
Gorfinkel, HJ1
Lemmo, JJ1
Graham, BW1
Moresco, KP1
Shapiro, RS1
Halton, KP1
Sadler, MA1
Emre, S1
Schwartz, M1
Stancato-Pasik, A1
Ramos, R1
Ottman, EH1
Gall, SA1
Beaughard, M1
Brasset, M1
John, G1
Massingham, R1
Perrotti, P1
Antropoli, C1
Molino, D1
De Stefano, G1
Antropoli, M1
Dong, E1
Shi, S1
Greer, IA1
Walker, JJ1
Calder, AA1
Forbes, CD1
Loirat, C1
Myers, AK1
Forman, G1
Torres Duarte, AP1
Penhos, J1
Ramwell, P1
Rubin, PC1
Horn, L1
Ahn, YS1
Jy, W1
Harrington, WJ1
Shanbaky, N1
Fernandez, LF1
Haynes, DH1
Sunkel, C1
Statkow, PR1

Reviews

1 review available for nifedipine and Thrombosis

ArticleYear
[Arterial hypertension in the newborn infant. Etiologies. Treatment].
    Archives francaises de pediatrie, 1988, Volume: 45, Issue:4

    Topics: Acebutolol; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Endoc

1988

Trials

1 trial available for nifedipine and Thrombosis

ArticleYear
Conservative treatment of acute thrombosed external hemorrhoids with topical nifedipine.
    Diseases of the colon and rectum, 2001, Volume: 44, Issue:3

    Topics: Acute Disease; Administration, Topical; Adult; Female; Hemorrhoids; Humans; Lidocaine; Male; Middle

2001

Other Studies

14 other studies available for nifedipine and Thrombosis

ArticleYear
Synthesis, platelet aggregation inhibitory activity, and in vivo antithrombotic activity of new 1,4-dihydropyridines.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:10

    Topics: Animals; Cats; Collagen; Dihydropyridines; Humans; Kinetics; Male; Mice; Nitrendipine; Platelet Aggr

1988
Massive pre-placental and subchorionic haematoma.
    Singapore medical journal, 2006, Volume: 47, Issue:12

    Topics: 17 alpha-Hydroxyprogesterone Caproate; Adult; Female; Fetal Membranes, Premature Rupture; Hematoma;

2006
Calcium antagonist withdrawal syndrome.
    British medical journal (Clinical research ed.), 1983, Jun-11, Volume: 286, Issue:6381

    Topics: Adult; Angina Pectoris; Humans; Male; Nifedipine; Pyridines; Substance Withdrawal Syndrome; Thrombos

1983
Comparison of the antithrombotic action of calcium antagonist drugs with dipyridamole in dogs.
    The American journal of cardiology, 1983, Volume: 51, Issue:3

    Topics: Animals; Blood Platelets; Calcium Channel Blockers; Dipyridamole; Disease Models, Animal; Dogs; Fibr

1983
Early coronary graft thrombosis following surgery for Prinzmetal's angina: treatment with nifedipine and thrombolysis.
    American heart journal, 1981, Volume: 101, Issue:1

    Topics: Angina Pectoris; Angina Pectoris, Variant; Coronary Artery Bypass; Fibrinolytic Agents; Humans; Male

1981
Doppler sonography in the posttransplant patient: use of nifedipine to detect hepatic arterial flow.
    AJR. American journal of roentgenology, 1994, Volume: 163, Issue:4

    Topics: Adult; Child; False Positive Reactions; Hepatic Artery; Humans; Infant; Liver Transplantation; Middl

1994
Myocardial infarction in the third trimester of pregnancy secondary to an aortic valve thrombus.
    Obstetrics and gynecology, 1993, Volume: 81, Issue:5 ( Pt 2)

    Topics: Adult; Aortic Valve; Female; Heart Valve Prosthesis; Heparin; Humans; Myocardial Infarction; Nifedip

1993
Failure of calcium channel blockade to reduce platelet-mediated cyclic flow variations in dogs with coronary stenosis and endothelial injury.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:4

    Topics: Animals; Aspirin; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiazem; Disea

1995
[Effects of the combination of aspirin and nifedipine on platelet aggregation and thrombogenesis].
    Zhonghua xin xue guan bing za zhi, 1990, Volume: 18, Issue:5

    Topics: Animals; Aspirin; Drug Synergism; Female; Male; Nifedipine; Platelet Aggregation; Platelet Aggregati

1990
Aspirin with an adrenergic or a calcium-channel-blocking agent as new combination therapy for arterial thrombosis.
    Lancet (London, England), 1985, Feb-09, Volume: 1, Issue:8424

    Topics: Aspirin; Drug Synergism; Ethanolamines; Humans; Labetalol; Nicardipine; Nifedipine; Platelet Aggrega

1985
Comparison of verapamil and nifedipine in thrombosis models.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1986, Volume: 183, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Collagen; Disease Models, Animal; Epinephrine; Male; N

1986
Preeclampsia: platelets and antiplatelet therapy.
    Hospital practice (Office ed.), 1988, May-30, Volume: 23, Issue:5A

    Topics: Aspirin; Blood Coagulation; Blood Platelets; Diagnosis, Differential; Female; Fetus; Humans; Hyperte

1988
Increased platelet calcium in thrombosis and related disorders and its correction by nifedipine.
    Thrombosis research, 1987, Jan-15, Volume: 45, Issue:2

    Topics: Arteriosclerosis; Blood Platelets; Calcium; Homeostasis; Humans; Nifedipine; Thrombosis; Vascular Di

1987
The antithrombogenic in vivo effects of calcium channel blockers in experimental thrombosis in mice.
    Thrombosis and haemostasis, 1987, Jun-03, Volume: 57, Issue:3

    Topics: Animals; Calcium Channel Blockers; Collagen; Dihydropyridines; Diltiazem; Disease Models, Animal; Do

1987
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