nifedipine has been researched along with Spasm in 34 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Spasm: An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have used a placebo controlled trial to investigate the effect of long-term administration of nifedipine in the prevention of symptomatic episodes of oesophageal spasm." | 9.06 | Trial of nifedipine for prevention of oesophageal spasm. ( Davies, HA; Henderson, AH; Lewis, MJ; Rhodes, J, 1987) |
| "Although nifedipine therapy resulted in substantial relief of dysphagia in six patients with diffuse esophageal spasm, significant side effects, particularly in young working subjects, precluded prolonged use." | 7.67 | Nifedipine therapy for diffuse esophageal spasm. ( Morse, J; Thomas, E; Willis, M; Witt, P, 1986) |
| "We report clinical experience with the coronary vasodilator nifedipine in 127 patients with symptoms of myocardial ischemia associated with electrocardiographic or angiographic evidence, or both, of coronary-artery spasm." | 7.66 | Nifedipine therapy for coronary-artery spasm. Experience in 127 patients. ( Achuff, S; Antman, E; Braunwald, E; Geltman, E; Goldberg, S; Heupler, F; Kerin, NZ; Liang, CS; MacAlpin, R; Muller, J; Neff, RK; Reichek, N; Rubenfire, M; Tabatznik, B, 1980) |
| "In a patient with variant angina, we have shown that the calcium-channel blocker nifedipine inhibits both spontaneous and ergonivine-induced coronary artery spasm." | 7.66 | The angiographic effect of ergonovine and nifedipine in coronary artery spasm. ( Al-Sadir, J; Ford, LE; Rich, S, 1980) |
| " The sublingual adminstration of nifedipine reversed both the acute and the delayed cerebral arterial spasm." | 7.66 | Cerebral arterial spasm: part 10. Reversal of acute and chronic spasm in dogs with orally administered nifedipine. ( Allen, GS; Bahr, AL, 1979) |
| "Nifedipine was evaluated in the management of eight patients with intractable coronary arterial spasm." | 7.66 | Nifedipine therapy for refractory coronary arterial spasm. ( Heupler, FA; Proudfit, WL, 1979) |
| "We have used a placebo controlled trial to investigate the effect of long-term administration of nifedipine in the prevention of symptomatic episodes of oesophageal spasm." | 5.06 | Trial of nifedipine for prevention of oesophageal spasm. ( Davies, HA; Henderson, AH; Lewis, MJ; Rhodes, J, 1987) |
| " Nifedipine has proved effective in preventing coronary arterial spasm in patients with Prinzmetal's angina." | 4.76 | Inappropriate coronary vasoconstriction in patients with coronary artery disease: a role for nifedipine? ( Green, L; Grossman, W; Gunther, S; Mudge, GH; Muller, JE, 1979) |
| "Although nifedipine therapy resulted in substantial relief of dysphagia in six patients with diffuse esophageal spasm, significant side effects, particularly in young working subjects, precluded prolonged use." | 3.67 | Nifedipine therapy for diffuse esophageal spasm. ( Morse, J; Thomas, E; Willis, M; Witt, P, 1986) |
| "We report clinical experience with the coronary vasodilator nifedipine in 127 patients with symptoms of myocardial ischemia associated with electrocardiographic or angiographic evidence, or both, of coronary-artery spasm." | 3.66 | Nifedipine therapy for coronary-artery spasm. Experience in 127 patients. ( Achuff, S; Antman, E; Braunwald, E; Geltman, E; Goldberg, S; Heupler, F; Kerin, NZ; Liang, CS; MacAlpin, R; Muller, J; Neff, RK; Reichek, N; Rubenfire, M; Tabatznik, B, 1980) |
| "In a patient with variant angina, we have shown that the calcium-channel blocker nifedipine inhibits both spontaneous and ergonivine-induced coronary artery spasm." | 3.66 | The angiographic effect of ergonovine and nifedipine in coronary artery spasm. ( Al-Sadir, J; Ford, LE; Rich, S, 1980) |
| " The sublingual adminstration of nifedipine reversed both the acute and the delayed cerebral arterial spasm." | 3.66 | Cerebral arterial spasm: part 10. Reversal of acute and chronic spasm in dogs with orally administered nifedipine. ( Allen, GS; Bahr, AL, 1979) |
| "Nifedipine was evaluated in the management of eight patients with intractable coronary arterial spasm." | 3.66 | Nifedipine therapy for refractory coronary arterial spasm. ( Heupler, FA; Proudfit, WL, 1979) |
| "The clinical response to therapy with the calcium-blocking agent nifedipine was assessed in 12 patients with variant angina pectoris who were 44 to 67 years old." | 3.66 | Nifedipine in the treatment of Prinzmetal's (variant) angina. ( Goldberg, S; Hirshfeld, JW; Kastor, JA; Muller, J; Reichek, N; Wilson, J, 1979) |
| "Based on in vivo studies on isolated muscle strips of the LES and on manometric in vivo studies on 8 mongrel dogs, 6 healthy volunteers, 6 patients with achalasia and 3 subjects with diffuse esophageal spasm we could demonstrate that nifedipine causes a long-lasting relaxation of smooth muscle, the esophagus and LES." | 3.65 | [Clinical and experimental studies on the efficiency of nifedipine on smooth muscle strips of the esophagus (author's transl)]. ( Golenhofen, K; Lepsien, G; Schattenmann, G; Siewert, R; Weiser, HF, 1977) |
| "Acute hypocalcemia is generally caused by a sudden drop in serum calcium ion and presents with a mild or severe form of tetany." | 1.91 | Hypocalcemic tetany associated with simultaneous administration of cimetidine and nifedipine: a case report. ( Bezabhe, WM; Bezabih, YM; Bimrew, MA, 2023) |
| "Levcromakalim was much less potent (427 fold) against the spasm evoked by KCl (80 mM) than against the spasm evoked by oxytocin (0." | 1.29 | Cellular localization of the inhibitory action of relaxin against uterine spasm. ( Hollingsworth, M; Hughes, SJ, 1995) |
| "Treatment with nifedipine did not significantly change any of the pulmonary function values, except for the carbon monoxide diffusing capacity (DLCO)." | 1.28 | Diffusing capacity of the lung and nifedipine in systemic sclerosis. ( Georgiakodis, F; Kyriakidis, M; Papazoglou, S; Sfikakis, P; Sfikakis, PP; Toutouzas, P; Vergos, C, 1990) |
| "Coronary spasm is due to strong contraction of coronary vascular smooth muscle cells which is triggered by an increase of intracellular calcium ions; hyperventilation plus TRIS-buffer infusion induces coronary spasm by decreasing hydrogen ions which antagonize the action of calcium ions." | 1.26 | Pathophysiology and treatment of coronary arterial spasm. ( Yasue, H, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (70.59) | 18.7374 |
| 1990's | 7 (20.59) | 18.2507 |
| 2000's | 2 (5.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Bezabih, YM | 1 |
| Bimrew, MA | 1 |
| Bezabhe, WM | 1 |
| Garrison, CP | 1 |
| Colman, N | 1 |
| Wieling, W | 1 |
| Wilde, AA | 1 |
| Nasrallah, SM | 2 |
| Beinart, C | 1 |
| Sos, TA | 1 |
| Saddekni, S | 1 |
| Weiner, MA | 1 |
| Sniderman, KW | 1 |
| Kemerer, VF | 1 |
| Dagher, FJ | 1 |
| Pais, SO | 1 |
| Bigot, A | 1 |
| Moreau, D | 1 |
| De Kersaint-Gilly, A | 1 |
| Pinaud, M | 1 |
| Antman, E | 1 |
| Muller, J | 2 |
| Goldberg, S | 2 |
| MacAlpin, R | 1 |
| Rubenfire, M | 1 |
| Tabatznik, B | 1 |
| Liang, CS | 1 |
| Heupler, F | 1 |
| Achuff, S | 1 |
| Reichek, N | 2 |
| Geltman, E | 1 |
| Kerin, NZ | 1 |
| Neff, RK | 1 |
| Braunwald, E | 1 |
| Yasue, H | 1 |
| Heupler, FA | 2 |
| Davies, HA | 2 |
| Lewis, M | 1 |
| Rhodes, J | 2 |
| Henderson, A | 1 |
| Rich, S | 1 |
| Ford, LE | 1 |
| Al-Sadir, J | 1 |
| Halstead, LS | 1 |
| Seager, SW | 1 |
| Houston, JM | 1 |
| Whitesell, K | 1 |
| Dennis, M | 1 |
| Nance, PW | 1 |
| Winterkorn, JM | 1 |
| Kupersmith, MJ | 1 |
| Wirtschafter, JD | 1 |
| Forman, S | 1 |
| Hughes, SJ | 1 |
| Hollingsworth, M | 1 |
| Gunther, S | 1 |
| Green, L | 1 |
| Muller, JE | 1 |
| Mudge, GH | 1 |
| Grossman, W | 1 |
| Allen, GS | 2 |
| Banghart, SB | 1 |
| Bahr, AL | 1 |
| Lown, B | 1 |
| Proudfit, WL | 1 |
| Wilson, J | 1 |
| Hirshfeld, JW | 1 |
| Kastor, JA | 1 |
| Kaltenbach, M | 1 |
| Schulz, W | 1 |
| Kober, G | 1 |
| Proudfit, W | 1 |
| Oliva, PB | 1 |
| Pearle, DL | 1 |
| Weiser, HF | 1 |
| Lepsien, G | 1 |
| Golenhofen, K | 1 |
| Schattenmann, G | 1 |
| Siewert, R | 1 |
| Gabrielian, ES | 2 |
| Akopov, SE | 2 |
| Grigorian, GS | 1 |
| Tunian, IuS | 1 |
| Ghazarian, AV | 1 |
| Sfikakis, PP | 1 |
| Kyriakidis, M | 1 |
| Vergos, C | 1 |
| Papazoglou, S | 1 |
| Georgiakodis, F | 1 |
| Toutouzas, P | 1 |
| Sfikakis, P | 1 |
| Gasser, P | 1 |
| Flammer, J | 1 |
| Guthauser, U | 1 |
| Mahler, F | 1 |
| Geller, LI | 1 |
| Petrenko, VF | 1 |
| Lewis, MJ | 1 |
| Henderson, AH | 1 |
| Thomas, E | 1 |
| Witt, P | 1 |
| Willis, M | 1 |
| Morse, J | 1 |
| Tommaso, CL | 1 |
| Singleton, RT | 1 |
| Backhaus, EA | 1 |
2 reviews available for nifedipine and Spasm
| Article | Year |
|---|---|
Syndrome of symptomatic coronary arterial spasm with nearly normal coronary arteriograms.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Coronary Angiography; Coronary Vessels; Electrocardiog | 1980 |
Inappropriate coronary vasoconstriction in patients with coronary artery disease: a role for nifedipine?
Topics: Angina Pectoris, Variant; Blood Pressure; Cardiac Catheterization; Cardiac Pacing, Artificial; Coron | 1979 |
2 trials available for nifedipine and Spasm
| Article | Year |
|---|---|
Trial of nifedipine for prevention of oesophageal spasm.
Topics: Adult; Double-Blind Method; Drug Evaluation; Esophageal Diseases; Female; Humans; Male; Middle Aged; | 1987 |
Primary esophageal motor disorders: clinical response to nifedipine.
Topics: Adult; Aged; Esophageal Achalasia; Esophageal Diseases; Esophagogastric Junction; Female; Humans; Ma | 1985 |
30 other studies available for nifedipine and Spasm
| Article | Year |
|---|---|
Hypocalcemic tetany associated with simultaneous administration of cimetidine and nifedipine: a case report.
Topics: Calcium Gluconate; Cimetidine; Dyspepsia; Female; Humans; Hypocalcemia; Middle Aged; Nifedipine; Spa | 2023 |
Nipple vasospasms, Raynaud's syndrome, and nifedipine.
Topics: Adult; Female; Humans; Muscle, Smooth, Vascular; Nifedipine; Nipples; Raynaud Disease; Spasm; Vascul | 2002 |
A patient with recurrent syncope and ST-elevation on the electrocardiogram.
Topics: Calcium Channel Blockers; Coronary Disease; Electrocardiography; Female; Humans; Middle Aged; Nifedi | 2004 |
Nifedipine in the treatment of diffuse oesophageal spasm.
Topics: Esophageal Diseases; Humans; Male; Middle Aged; Nifedipine; Pyridines; Spasm | 1982 |
Arterial spasm during renal angioplasty.
Topics: Adolescent; Adult; Aged; Angioplasty, Balloon; Arterial Occlusive Diseases; Arteriosclerosis; Child; | 1983 |
Successful treatment of ergotism with nifedipine.
Topics: Angiography; Aortography; Caffeine; Drug Combinations; Ergotamine; Ergotism; Female; Humans; Ischemi | 1984 |
[Prevention of vascular spasm during hyperselective carotid-vertebral catheterization].
Topics: Adult; Carotid Artery Diseases; Catheterization; Humans; Isosorbide Dinitrate; Nifedipine; Spasm; Ve | 1983 |
Nifedipine therapy for coronary-artery spasm. Experience in 127 patients.
Topics: Adult; Aged; Angina Pectoris; Angina Pectoris, Variant; Coronary Disease; Female; Humans; Male; Midd | 1980 |
Pathophysiology and treatment of coronary arterial spasm.
Topics: Adult; Angina Pectoris; Angina Pectoris, Variant; Atropine; Calcium; Coronary Disease; Coronary Vess | 1980 |
Nifedipine for relief of esophageal chest pain?
Topics: Esophageal Diseases; Humans; Nifedipine; Pain; Pyridines; Spasm; Thorax | 1982 |
The angiographic effect of ergonovine and nifedipine in coronary artery spasm.
Topics: Adult; Coronary Vessels; Electrocardiography; Ergonovine; Humans; Male; Nifedipine; Pyridines; Radio | 1980 |
Relief of spasticity in SCI men and women using rectal probe electrostimulation.
Topics: Adult; Electric Stimulation Therapy; Equipment and Supplies; Female; Humans; Knee; Male; Motion; Nif | 1993 |
Brief report: treatment of vasospastic amaurosis fugax with calcium-channel blockers.
Topics: Adult; Aged; Blindness; Carotid Stenosis; Embolism; Female; Humans; Male; Middle Aged; Nifedipine; R | 1993 |
Cellular localization of the inhibitory action of relaxin against uterine spasm.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Benzopyrans; Calcium; Calcium Channel Agonists; Calciu | 1995 |
Cerebral arterial spasm: part 9. In vitro effects of nifedipine on serotonin-, phenylephrine-, and potassium-induced contractions of canine basilar and femoral arteries.
Topics: Animals; Basilar Artery; Calcium; Cerebral Arterial Diseases; Dogs; Dose-Response Relationship, Drug | 1979 |
Cerebral arterial spasm: part 10. Reversal of acute and chronic spasm in dogs with orally administered nifedipine.
Topics: Acute Disease; Administration, Oral; Animals; Cerebral Arterial Diseases; Chronic Disease; Dogs; Dru | 1979 |
Symposium on nifedipine and calcium flux inhibition in the treatment of coronary arterial spasm and myocardial ischemia. Introduction.
Topics: Adult; Angina Pectoris; Calcium; Cardiomyopathies; Coronary Disease; Electrocardiography; Humans; Ma | 1979 |
Nifedipine therapy for refractory coronary arterial spasm.
Topics: Adult; Aged; Coronary Disease; Ergonovine; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; | 1979 |
Nifedipine in the treatment of Prinzmetal's (variant) angina.
Topics: Adult; Aged; Angina Pectoris; Angina Pectoris, Variant; Cold Temperature; Coronary Angiography; Dose | 1979 |
Effects of nifedipine after intravenous and intracoronary administration.
Topics: Aged; Angina Pectoris; Angina Pectoris, Variant; Coronary Circulation; Coronary Vessels; Dose-Respon | 1979 |
Types of spasm and their diagnosis.
Topics: Angina Pectoris, Variant; Coronary Disease; Diagnosis, Differential; Humans; Nifedipine; Spasm | 1979 |
Nifedipine in variant angina and role of spasm in ischemic heart disease.
Topics: Angina Pectoris; Angina Pectoris, Variant; Coronary Disease; Humans; Nifedipine; Pyridines; Spasm | 1979 |
Clinical experience with nifedipine for coronary artery spasm.
Topics: Aged; Angina Pectoris, Variant; Coronary Vessels; Female; Humans; Middle Aged; Nifedipine; Pyridines | 1979 |
[Clinical and experimental studies on the efficiency of nifedipine on smooth muscle strips of the esophagus (author's transl)].
Topics: Adult; Animals; Dogs; Dose-Response Relationship, Drug; Esophageal Achalasia; Esophagus; Female; Hum | 1977 |
["Dynamic" component of carotid artery stenosis in patients with cerebrovascular disorders].
Topics: Adult; Aged; Brain; Brain Ischemia; Carotid Artery Diseases; Carotid Artery, Internal; Humans; Middl | 1991 |
Cerebral-artery spasm in vitro.
Topics: Arteriosclerosis; Cerebral Arteries; Dinoprost; Humans; In Vitro Techniques; Muscle Contraction; Nif | 1990 |
Diffusing capacity of the lung and nifedipine in systemic sclerosis.
Topics: Adult; Carbon Monoxide; Drug Administration Schedule; Female; Hemodynamics; Humans; Lung Diseases; M | 1990 |
Do vasospasms provoke ocular diseases?
Topics: Adolescent; Adult; Aged; Blood Flow Velocity; Capillaries; Cold Temperature; Fingers; Glaucoma; Huma | 1990 |
[Disorders of esophageal motility as a cause of retrosternal pain].
Topics: Adult; Diagnosis, Differential; Esophageal Diseases; Esophagitis, Peptic; Female; Gastrointestinal M | 1986 |
Nifedipine therapy for diffuse esophageal spasm.
Topics: Dizziness; Drug Evaluation; Esophageal Diseases; Female; Headache; Humans; Male; Manometry; Nifedipi | 1986 |