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nifedipine and Schizophrenia

nifedipine has been researched along with Schizophrenia in 10 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
"We investigated the efficacy of nilvadipine, a calcium channel inhibitor, for psychiatric symptoms and tardive dyskinesia in 30 patients with chronic schizophrenia in a placebo-controlled double-blind crossover study."9.08Nilvadipine is effective for chronic schizophrenia in a double-blind placebo-controlled study. off. ( Asai, M; Ashikari, I; Kanba, S; Ohnishi, K; Yagi, G; Yamada, K, 1996)
"Effects of the dihydropyridine calcium channel inhibitor nifedipine on chronic schizophrenia and tardive dyskinesia were studied in an 8-week double-blind crossover trial."9.07A clinical trial of nifedipine in schizophrenia and tardive dyskinesia. ( Bigelow, LB; Freed, WJ; Kirch, DG; Straw, GM; Suddath, RL; Wyatt, RJ, 1991)
"Nilvadipine is a calcium channel inhibitor used commonly for the treatment of cerebrovascular insufficiency."5.29Effectiveness of nilvadipine in two cases of chronic schizophrenia. ( Asai, M; Ashikari, I; Kanba, S; Onishi, K; Yagi, G; Yamada, K, 1995)
" Fifty-one patients diagnosed with paranoid schizophrenia received haloperidol in combination with nifedipine (25 patients) or haloperidol only (26 patients) during 26 weeks."5.13[The use of nifedipine as a corrector of extrapyramidal side-effects of classical neuroleptics]. ( Popov, MIu, 2008)
"We investigated the efficacy of nilvadipine, a calcium channel inhibitor, for psychiatric symptoms and tardive dyskinesia in 30 patients with chronic schizophrenia in a placebo-controlled double-blind crossover study."5.08Nilvadipine is effective for chronic schizophrenia in a double-blind placebo-controlled study. off. ( Asai, M; Ashikari, I; Kanba, S; Ohnishi, K; Yagi, G; Yamada, K, 1996)
"We examined whether nifedipine, a calcium channel antagonist, added to a stable regimen of neuroleptic medication would affect cognition in patients with chronic schizophrenia or schizoaffective disorder who had tardive dyskinesia."5.08Effects of nifedipine, a calcium channel antagonist, on cognitive function in schizophrenic patients with tardive dyskinesia. ( Deutsch, SI; Fay-McCarthy, M; Kendrick, K; Rosse, RB; Schwartz, BL, 1997)
"In an open label study, two fixed doses of nifedipine (30 mg and 60 mg daily) were added to the usual antipsychotic drug treatments of 10 patients suffering from chronic schizophrenia."5.07Effects of nifedipine on psychosis and tardive dyskinesia in schizophrenic patients. ( Eyles, D; Pond, SM; Stedman, TJ; Welham, JL; Whiteford, HA, 1991)
"Effects of the dihydropyridine calcium channel inhibitor nifedipine on chronic schizophrenia and tardive dyskinesia were studied in an 8-week double-blind crossover trial."5.07A clinical trial of nifedipine in schizophrenia and tardive dyskinesia. ( Bigelow, LB; Freed, WJ; Kirch, DG; Straw, GM; Suddath, RL; Wyatt, RJ, 1991)
"Nilvadipine is a calcium channel inhibitor used commonly for the treatment of cerebrovascular insufficiency."1.29Effectiveness of nilvadipine in two cases of chronic schizophrenia. ( Asai, M; Ashikari, I; Kanba, S; Onishi, K; Yagi, G; Yamada, K, 1995)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's6 (60.00)18.2507
2000's2 (20.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Popov, MIu1
Dzhuga, NP1
Kozlovskiĭ, VL1
Solís-Chagoyán, H1
Calixto, E1
Figueroa, A1
Montaño, LM1
Berlanga, C1
Rodríguez-Verdugo, MS1
Romo, F1
Jiménez, M1
Gurrola, CZ1
Riquelme, A1
Benítez-King, G1
Yamada, K2
Kanba, S2
Ashikari, I2
Ohnishi, K1
Yagi, G2
Asai, M2
Onishi, K1
Schwartz, BL1
Fay-McCarthy, M1
Kendrick, K1
Rosse, RB1
Deutsch, SI1
Stedman, TJ1
Whiteford, HA1
Eyles, D1
Welham, JL1
Pond, SM1
Suddath, RL1
Straw, GM1
Freed, WJ1
Bigelow, LB1
Kirch, DG1
Wyatt, RJ1
Duncan, E1
Adler, L1
Angrist, B1
Rotrosen, J1
Kramer, MS1
DeMaria, P1
Morrow, R1
DiJohnson, C1
Sheves, P1

Trials

6 trials available for nifedipine and Schizophrenia

ArticleYear
[The use of nifedipine as a corrector of extrapyramidal side-effects of classical neuroleptics].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2008, Volume: 108, Issue:6

    Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Female; Haloperidol; Humans; Male; Nifedipine;

2008
Nilvadipine is effective for chronic schizophrenia in a double-blind placebo-controlled study. off.
    Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:6

    Topics: Adult; Aged; Calcium Channel Blockers; Chronic Disease; Cross-Over Studies; Double-Blind Method; Dys

1996
Effects of nifedipine, a calcium channel antagonist, on cognitive function in schizophrenic patients with tardive dyskinesia.
    Clinical neuropharmacology, 1997, Volume: 20, Issue:4

    Topics: Aged; Calcium Channel Blockers; Cognition; Cross-Over Studies; Double-Blind Method; Dyskinesia, Drug

1997
Effects of nifedipine on psychosis and tardive dyskinesia in schizophrenic patients.
    Journal of clinical psychopharmacology, 1991, Volume: 11, Issue:1

    Topics: Adult; Antipsychotic Agents; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Haloperido

1991
A clinical trial of nifedipine in schizophrenia and tardive dyskinesia.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:3

    Topics: Adult; Antipsychotic Agents; Benztropine; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Hum

1991
Nifedipine in the treatment of tardive dyskinesia.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:6

    Topics: Adult; Antipsychotic Agents; Dyskinesia, Drug-Induced; Humans; Male; Middle Aged; Neurologic Examina

1990

Other Studies

4 other studies available for nifedipine and Schizophrenia

ArticleYear
[Effect of nifedipine on the effectiveness of antipsychotic therapy in schizophrenia].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2009, Volume: 109, Issue:8

    Topics: Adult; Antipsychotic Agents; Calcium Channel Blockers; Cognition; Dibenzothiazepines; Dose-Response

2009
Microtubule organization and L-type voltage-activated calcium current in olfactory neuronal cells obtained from patients with schizophrenia and bipolar disorder.
    Schizophrenia research, 2013, Volume: 143, Issue:2-3

    Topics: Biomarkers; Bipolar Disorder; Calcium; Calcium Channels, L-Type; Cells, Cultured; Humans; Microtubul

2013
Effectiveness of nilvadipine in two cases of chronic schizophrenia.
    Psychiatry and clinical neurosciences, 1995, Volume: 49, Issue:4

    Topics: Calcium Channel Blockers; Chronic Disease; Dyskinesia, Drug-Induced; Humans; Male; Middle Aged; Nife

1995
Nifedipine in neuroleptic-refractory schizophrenia.
    Journal of clinical psychopharmacology, 1987, Volume: 7, Issue:3

    Topics: Adult; Antipsychotic Agents; Drug Resistance; Humans; Male; Middle Aged; Nifedipine; Psychiatric Sta

1987