Page last updated: 2024-11-01

nifedipine and Retinitis Pigmentosa

nifedipine has been researched along with Retinitis Pigmentosa in 8 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Retinitis Pigmentosa: Hereditary, progressive degeneration of the retina due to death of ROD PHOTORECEPTORS initially and subsequent death of CONE PHOTORECEPTORS. It is characterized by deposition of pigment in the retina.

Research Excerpts

ExcerptRelevanceReference
"To assess the long-term effects of nilvadipine on the progression of central visual field defect in retinitis pigmentosa (RP)."9.17Long-term effects of nilvadipine against progression of the central visual field defect in retinitis pigmentosa: an extended study. ( Ito, T; Kudo, T; Metoki, T; Nakazawa, M; Ohguro, H; Suzuki, Y, 2013)
"To assess the effects of nilvadipine on the progression of central visual field defect in retinitis pigmentosa (RP)."9.15Effect of nilvadipine on central visual field in retinitis pigmentosa: a 30-month clinical trial. ( Ito, T; Metoki, T; Miyagawa, Y; Nakazawa, M; Ohguro, H; Takeuchi, K, 2011)
"To assess the long-term effects of nilvadipine on the progression of central visual field defect in retinitis pigmentosa (RP)."5.17Long-term effects of nilvadipine against progression of the central visual field defect in retinitis pigmentosa: an extended study. ( Ito, T; Kudo, T; Metoki, T; Nakazawa, M; Ohguro, H; Suzuki, Y, 2013)
"To assess the effects of nilvadipine on the progression of central visual field defect in retinitis pigmentosa (RP)."5.15Effect of nilvadipine on central visual field in retinitis pigmentosa: a 30-month clinical trial. ( Ito, T; Metoki, T; Miyagawa, Y; Nakazawa, M; Ohguro, H; Takeuchi, K, 2011)
"Nilvadipine was administered from P7 to P28."1.37AAV-mediated gene replacement, either alone or in combination with physical and pharmacological agents, results in partial and transient protection from photoreceptor degeneration associated with betaPDE deficiency. ( Allocca, M; Auricchio, A; Di Vicino, U; Iodice, C; Manfredi, A, 2011)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nakazawa, M5
Suzuki, Y1
Ito, T2
Metoki, T5
Kudo, T1
Ohguro, H6
Takeuchi, K1
Miyagawa, Y2
Sakamoto, K1
Mori, A1
Nakahara, T1
Ishii, K1
Allocca, M1
Manfredi, A1
Iodice, C1
Di Vicino, U1
Auricchio, A1
Sato, M1
Ohguro, I2
Mamiya, K2
Takano, Y3
Yamazaki, H3
Ishikawa, F2
Dezawa, M2
Ishikawa, H1
Maeda, T1
Maruyama, I1
Sawada, H1

Reviews

2 reviews available for nifedipine and Retinitis Pigmentosa

ArticleYear
[Cause of retinitis pigmentosa and new therapeutics under development].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2011, Volume: 137, Issue:1

    Topics: Animals; c-Mer Tyrosine Kinase; Carrier Proteins; cis-trans-Isomerases; Cyclic Nucleotide Phosphodie

2011
[New drug therapy for retinal degeneration].
    Nippon Ganka Gakkai zasshi, 2008, Volume: 112, Issue:1

    Topics: Animals; Calcium Channel Blockers; Dark Adaptation; Disease Models, Animal; Humans; Mice; Mutation;

2008

Trials

2 trials available for nifedipine and Retinitis Pigmentosa

ArticleYear
Long-term effects of nilvadipine against progression of the central visual field defect in retinitis pigmentosa: an extended study.
    BioMed research international, 2013, Volume: 2013

    Topics: Adult; Aged; Calcium Channel Blockers; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nifedip

2013
Effect of nilvadipine on central visual field in retinitis pigmentosa: a 30-month clinical trial.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2011, Volume: 225, Issue:2

    Topics: Administration, Oral; Adult; Aged; Calcium Channel Blockers; Disease Progression; Female; Follow-Up

2011

Other Studies

4 other studies available for nifedipine and Retinitis Pigmentosa

ArticleYear
AAV-mediated gene replacement, either alone or in combination with physical and pharmacological agents, results in partial and transient protection from photoreceptor degeneration associated with betaPDE deficiency.
    Investigative ophthalmology & visual science, 2011, Jul-29, Volume: 52, Issue:8

    Topics: Animals; Calcium Channel Blockers; Chlorocebus aethiops; Combined Modality Therapy; COS Cells; Cycli

2011
Study of pharmacological effects of nilvadipine on RCS rat retinal degeneration by microarray analysis.
    Biochemical and biophysical research communications, 2003, Jul-11, Volume: 306, Issue:4

    Topics: Animals; Apoptosis; Blotting, Western; Calcium Channel Blockers; Cell Death; Fibroblast Growth Facto

2003
Study of drug effects of calcium channel blockers on retinal degeneration of rd mouse.
    Biochemical and biophysical research communications, 2004, Jan-23, Volume: 313, Issue:4

    Topics: Animals; Calcium Channel Blockers; Caspases; Diltiazem; Electroretinography; Fibroblast Growth Facto

2004
Preservation of retinal morphology and functions in royal college surgeons rat by nilvadipine, a Ca(2+) antagonist.
    Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:4

    Topics: Animals; Blotting, Western; Calcium Channel Blockers; Caspase 1; Caspase 2; Caspases; Crystallins; D

2002