Page last updated: 2024-11-01

nifedipine and Retinal Degeneration

nifedipine has been researched along with Retinal Degeneration in 5 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Retinal Degeneration: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)

Research Excerpts

ExcerptRelevanceReference
"To investigate the effect of nilvadipine, a calcium channel blocker, upon the retina of retinal degeneration slow (rds) mouse, nilvadipine was intraperitoneally injected into heterozygous rds mice for up to 200 days."7.74Systemic administration of nilvadipine delays photoreceptor degeneration of heterozygous retinal degeneration slow (rds) mouse. ( Mizukoshi, S; Nakazawa, M; Takeuchi, K, 2008)
"To investigate the effect of nilvadipine, a calcium channel blocker, upon the retina of retinal degeneration slow (rds) mouse, nilvadipine was intraperitoneally injected into heterozygous rds mice for up to 200 days."3.74Systemic administration of nilvadipine delays photoreceptor degeneration of heterozygous retinal degeneration slow (rds) mouse. ( Mizukoshi, S; Nakazawa, M; Takeuchi, K, 2008)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sato, M1
Ohguro, H3
Ohguro, I3
Mamiya, K3
Takano, Y3
Yamazaki, H3
Metoki, T2
Miyagawa, Y1
Ishikawa, F3
Nakazawa, M4
Dezawa, M1
Ishikawa, H1
Takeuchi, K1
Mizukoshi, S1
Mergler, S1
Steinhausen, K1
Wiederholt, M1
Strauss, O1

Other Studies

5 other studies available for nifedipine and Retinal Degeneration

ArticleYear
Study of pharmacological effects of nilvadipine on RCS rat retinal degeneration by microarray analysis.
    Biochemical and biophysical research communications, 2003, Jul-11, Volume: 306, Issue:4

    Topics: Animals; Apoptosis; Blotting, Western; Calcium Channel Blockers; Cell Death; Fibroblast Growth Facto

2003
Low expression of rhodopsin kinase in pineal gland in Royal College of Surgeons rat.
    Current eye research, 2003, Volume: 27, Issue:2

    Topics: Animals; Arrestin; Blotting, Western; Calcium Channel Blockers; Calcium-Binding Proteins; Disease Mo

2003
Study of drug effects of calcium channel blockers on retinal degeneration of rd mouse.
    Biochemical and biophysical research communications, 2004, Jan-23, Volume: 313, Issue:4

    Topics: Animals; Calcium Channel Blockers; Caspases; Diltiazem; Electroretinography; Fibroblast Growth Facto

2004
Systemic administration of nilvadipine delays photoreceptor degeneration of heterozygous retinal degeneration slow (rds) mouse.
    Experimental eye research, 2008, Volume: 86, Issue:1

    Topics: Animals; Blotting, Western; Calcium Channel Blockers; Disease Models, Animal; Drug Evaluation, Precl

2008
Altered regulation of L-type channels by protein kinase C and protein tyrosine kinases as a pathophysiologic effect in retinal degeneration.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1998, Volume: 12, Issue:12

    Topics: Alkaloids; Animals; Animals, Newborn; Benzophenanthridines; Benzoquinones; Calcium; Calcium Channels

1998