nifedipine has been researched along with Pulmonary Fibrosis in 8 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Long-term therapy with aerosolized iloprost (long-acting PGI(2) analog) resulted in unequivocal clinical improvement from a state of immobilization and severe resting dyspnea in a patient with decompensated right heart failure." | 9.09 | Inhaled prostacyclin and iloprost in severe pulmonary hypertension secondary to lung fibrosis. ( Ghofrani, HA; Grimminger, F; Olschewski, H; Schermuly, R; Seeger, W; Temmesfeld-Wollbruck, B; Walmrath, D, 1999) |
| "The present study was undertaken to evaluate at rest the short- and long-term effects of oral nifedipine (N) in patients with pulmonary hypertension (PH)." | 7.68 | Short- and long-term hemodynamic effects of oral nifedipine in patients with pulmonary hypertension secondary to COPD and lung fibrosis. Deleterious effects in patients with restrictive disease. ( Domenighetti, GM; Saglini, VG, 1992) |
| "To detect whether pulmonary vascular responsiveness is a factor which can aggravate the pulmonary hypertension induced by irreversible pulmonary fibrosis, we examined the acute hemodynamic effects of low-flow oxygen and of nifedipine both at rest and during exercise in 8 patients with idiopathic pulmonary fibrosis (IPF)." | 7.67 | Pulmonary vascular responsiveness at rest and during exercise in idiopathic pulmonary fibrosis: effects of oxygen and nifedipine. ( Galavotti, V; Gunella, G; Papiris, S; Sturani, C, 1986) |
| " Long-term therapy with aerosolized iloprost (long-acting PGI(2) analog) resulted in unequivocal clinical improvement from a state of immobilization and severe resting dyspnea in a patient with decompensated right heart failure." | 5.09 | Inhaled prostacyclin and iloprost in severe pulmonary hypertension secondary to lung fibrosis. ( Ghofrani, HA; Grimminger, F; Olschewski, H; Schermuly, R; Seeger, W; Temmesfeld-Wollbruck, B; Walmrath, D, 1999) |
| "The present study was undertaken to evaluate at rest the short- and long-term effects of oral nifedipine (N) in patients with pulmonary hypertension (PH)." | 3.68 | Short- and long-term hemodynamic effects of oral nifedipine in patients with pulmonary hypertension secondary to COPD and lung fibrosis. Deleterious effects in patients with restrictive disease. ( Domenighetti, GM; Saglini, VG, 1992) |
| "To detect whether pulmonary vascular responsiveness is a factor which can aggravate the pulmonary hypertension induced by irreversible pulmonary fibrosis, we examined the acute hemodynamic effects of low-flow oxygen and of nifedipine both at rest and during exercise in 8 patients with idiopathic pulmonary fibrosis (IPF)." | 3.67 | Pulmonary vascular responsiveness at rest and during exercise in idiopathic pulmonary fibrosis: effects of oxygen and nifedipine. ( Galavotti, V; Gunella, G; Papiris, S; Sturani, C, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mukherjee, S | 1 |
| Ayaub, EA | 1 |
| Murphy, J | 1 |
| Lu, C | 1 |
| Kolb, M | 1 |
| Ask, K | 1 |
| Janssen, LJ | 1 |
| Bergemann, A | 1 |
| Tikly, M | 1 |
| Olschewski, H | 1 |
| Ghofrani, HA | 1 |
| Walmrath, D | 1 |
| Schermuly, R | 1 |
| Temmesfeld-Wollbruck, B | 1 |
| Grimminger, F | 1 |
| Seeger, W | 1 |
| Domenighetti, GM | 1 |
| Saglini, VG | 1 |
| Grisanti, M | 1 |
| Vicencio, M | 1 |
| Sturani, C | 1 |
| Papiris, S | 1 |
| Galavotti, V | 1 |
| Gunella, G | 1 |
| Ohar, J | 1 |
| Polatty, C | 1 |
| Robichaud, A | 1 |
| Fowler, A | 1 |
| Vetrovec, G | 1 |
| Glauser, F | 1 |
| Domenighetti, G | 1 |
1 trial available for nifedipine and Pulmonary Fibrosis
| Article | Year |
|---|---|
Inhaled prostacyclin and iloprost in severe pulmonary hypertension secondary to lung fibrosis.
Topics: Administration, Inhalation; Adult; Aged; Atrial Function, Right; Calcium Channel Blockers; Drug Ther | 1999 |
7 other studies available for nifedipine and Pulmonary Fibrosis
| Article | Year |
|---|---|
Disruption of Calcium Signaling in Fibroblasts and Attenuation of Bleomycin-Induced Fibrosis by Nifedipine.
Topics: Animals; Bleomycin; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Chan | 2015 |
Cystic lung disease in systemic sclerosis: a case report with high resolution computed tomography findings.
Topics: Adult; Antirheumatic Agents; Cysts; Female; Humans; Lung Diseases; Nifedipine; Penicillamine; Pulmon | 1996 |
Short- and long-term hemodynamic effects of oral nifedipine in patients with pulmonary hypertension secondary to COPD and lung fibrosis. Deleterious effects in patients with restrictive disease.
Topics: Aged; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Male; Middl | 1992 |
[Pulmonary involvement in progressive systemic sclerosis].
Topics: Humans; Hypertension, Pulmonary; Lung Diseases; Nifedipine; Penicillamine; Pulmonary Fibrosis; Scler | 1986 |
Pulmonary vascular responsiveness at rest and during exercise in idiopathic pulmonary fibrosis: effects of oxygen and nifedipine.
Topics: Adult; Blood Pressure; Exercise Test; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Ni | 1986 |
The role of vasodilators in patients with progressive systemic sclerosis. Interstitial lung disease and pulmonary hypertension.
Topics: Humans; Hydralazine; Hypertension, Pulmonary; Lung Diseases; Nifedipine; Pulmonary Fibrosis; Sarcoid | 1985 |
[Variable hemodynamic response to nifedipine in pulmonary hypertension secondary to chronic obstructive bronchopathy and pulmonary fibrosis].
Topics: Blood Pressure; Cardiac Output; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases | 1985 |