Page last updated: 2024-11-01

nifedipine and Proteinuria

nifedipine has been researched along with Proteinuria in 35 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"Nifedipine GITS was superior to enalapril in controlling ambulatory blood pressure, but they were equivalent in reducing proteinuria (37%)."9.08Equivalent reduction of proteinuria in hypertensives by either nifedipine GITS or enalapril: disparate effects on neurohormones and ambulatory blood pressure and the influence of salt. ( DeQuattro, V; Lee, DP, 1997)
"Our study compared the effects of an angiotensin-converting enzyme inhibitor (captopril) versus a calcium antagonist (nifedipine) on proteinuria and renal function in patients with diabetic nephropathy."9.07Comparative effects of captopril versus nifedipine on proteinuria and renal function of type 2 diabetic patients. ( Audi, L; Lucas, A; Romero, R; Salinas, I; Sanmarti, A; Teixidó, J, 1992)
" Hypertension was treated by nifedipine retard and occasionally by furosemide."7.69Management of moderate to severe hypertension and proteinuria by nifedipine retard and perindopril after renal transplantation. ( Alivanis, P; Dioudis, C; Goutsaridis, N; Grekas, D; Kalevrosoglou, I; Papoulidou, F; Tourkantonis, A, 1995)
" Next, in a randomized double-blind crossover study of 27 subjects with proteinuric CKD, we examined the effects of 6 weeks of treatment with placebo, sitaxentan (endothelin A antagonist), and nifedipine on these peptides alongside the primary end points of proteinuria, blood pressure, and arterial stiffness."5.20Plasma pro-endothelin-1 peptide concentrations rise in chronic kidney disease and following selective endothelin A receptor antagonism. ( Chariyavilaskul, P; Corder, R; Dhaun, N; Goddard, J; Kimmitt, RA; MacIntyre, IM; Webb, DJ; Wood, EG; Yuzugulen, J, 2015)
" We conducted a randomized, double-blind, three-way crossover study in 27 patients with proteinuric CKD to compare the effects of the ET(A) receptor antagonist sitaxentan, nifedipine, and placebo on proteinuria, BP, arterial stiffness, and various cardiovascular biomarkers."5.17Endothelin-A receptor antagonism modifies cardiovascular risk factors in CKD. ( Blackwell, S; Dhaun, N; Goddard, J; Johnston, NR; Melville, V; Talwar, DK; Webb, DJ, 2013)
" Angiotensin converting enzyme inhibitors (ACE-I) significantly retarded the development of end-stage renal failure compared to antihypertensives other than ACE-I (mostly nifedipine), and the effect was evident particularly in patients with proteinuria below the median (2."5.08Predictors of the progression of diabetic nephropathy and the beneficial effect of angiotensin-converting enzyme inhibitors in NIDDM patients. ( Babazono, T; Hirayama, M; Ishii, A; Omori, Y; Takahashi, C; Takeda, M; Tomonaga, O; Ujihara, U; Yokoyama, H, 1997)
"Nifedipine GITS was superior to enalapril in controlling ambulatory blood pressure, but they were equivalent in reducing proteinuria (37%)."5.08Equivalent reduction of proteinuria in hypertensives by either nifedipine GITS or enalapril: disparate effects on neurohormones and ambulatory blood pressure and the influence of salt. ( DeQuattro, V; Lee, DP, 1997)
"In a randomized controlled trial 10 patients with renal disease and proteinuria were treated with a dose of 10 mg nifedipine o."5.08Effects of low-dose nifedipine on urinary protein excretion rate in patients with renal disease. ( Huysmans, FT; Kloke, HJ; Koene, RA; Wetzels, JF, 1998)
"At 21 months, both patient groups had similar levels of blood pressure control, however, only the diltiazem group had a change in proteinuria (4+/-10%delta, nifedipine vs."5.08Differential effects of calcium channel blockers on size selectivity of proteinuria in diabetic glomerulopathy. ( Bakris, GL; Smith, AC; Toto, R, 1998)
"Our study compared the effects of an angiotensin-converting enzyme inhibitor (captopril) versus a calcium antagonist (nifedipine) on proteinuria and renal function in patients with diabetic nephropathy."5.07Comparative effects of captopril versus nifedipine on proteinuria and renal function of type 2 diabetic patients. ( Audi, L; Lucas, A; Romero, R; Salinas, I; Sanmarti, A; Teixidó, J, 1992)
" Enalapril and losartan reduced proteinuria but nifedipine did not."3.71Effects of antihypertensive therapy on intrarenal angiotensin and bradykinin levels in experimental renal insufficiency. ( Campbell, DJ; Mackie, FE; Meyer, TW, 2002)
"Cyclosporine (CsA) (45 mg/kg/day for 7 days) administration in female Wistar rats induced significant decrease in creatinine clearance (Ccr) and body weight loss (BWL)."3.70Effect of nifedipine in cyclosporine-induced nephrotoxicity in rats: roles of the thromboxane and endothelin systems. ( Darlametsos, IE; Papanikolaou, EN; Varonos, DD, 2000)
"The short-term effects of nifedipine on glomerular hemodynamics, sieving function, and renal tubular function were assessed in 10 patients suffering from biopsy-verified chronic glomerulonephritis."3.69Contrasting short-term effects of nifedipine on glomerular and tubular functions in glomerulonephritic patients. ( Berg, KJ; Fauchald, P; Hartmann, A; Holdaas, H; Lund, K; Reisaeter, A, 1994)
" Hypertension was treated by nifedipine retard and occasionally by furosemide."3.69Management of moderate to severe hypertension and proteinuria by nifedipine retard and perindopril after renal transplantation. ( Alivanis, P; Dioudis, C; Goutsaridis, N; Grekas, D; Kalevrosoglou, I; Papoulidou, F; Tourkantonis, A, 1995)
"In this study we investigated whether the increase in proteinuria induced by an oral protein load may be prevented by the angiotensin-converting enzyme inhibitor (ACEI) captopril in patients with nephrotic syndrome, and whether the effects of captopril on renal haemodynamics and/or glomerular selectivity are comparable to those obtained with the nonsteroidal anti-inflammatory drug (NSAID) indomethacin and the calcium-channel blocker (CaCB) nifedipine."3.69Renal effects of captopril, indomethacin and nifedipine in nephrotic patients after an oral protein load. ( Allegri, L; Borghetti, A; Buzio, C; Garini, G; Mazzi, A; Mutti, A; Savazzi, G, 1996)
"Proteinuria is associated with adverse cardiovascular and renal outcomes that are not prevented by current treatments."2.76Selective endothelin-A receptor antagonism reduces proteinuria, blood pressure, and arterial stiffness in chronic proteinuric kidney disease. ( Dhaun, N; Goddard, J; Haughie, S; Johnston, NR; Kerr, D; MacIntyre, IM; Melville, V; Webb, DJ, 2011)
"Subsequently preeclampsia developed and uteroplacental dysfunction deteriorated."1.34Severe, early-onset hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome episode with spontaneous remission during pregnancy. ( Gembruch, U; Merz, WM, 2007)
"Hypertension was treated with enalapril, enalapril and nifedepine and nifedepine alone."1.29Proteinuria in essential hypertension. ( Doifode, DV; Kate, SK; Soni, PS, 1994)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.86)18.7374
1990's21 (60.00)18.2507
2000's7 (20.00)29.6817
2010's6 (17.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hammoud, SH1
Alkhansa, S1
Mahjoub, N1
Omar, AG1
El-Mas, MM1
Eid, AA1
Alexander, JM1
Wilson, KL1
Dhaun, N4
Yuzugulen, J1
Kimmitt, RA1
Wood, EG1
Chariyavilaskul, P1
MacIntyre, IM3
Goddard, J4
Webb, DJ4
Corder, R1
Laster, M1
Im, D1
Ahn, A1
Ho, CH1
Melville, V3
Lilitkarntakul, P1
Johnston, NR3
Li, J2
Li, QX2
Xie, XF1
Ao, Y1
Tie, CR1
Song, RJ1
Kerr, D1
Haughie, S1
Blackwell, S1
Talwar, DK1
Liu, LL1
Xia, L1
Shao, L1
Merz, WM1
Gembruch, U1
Hartmann, A1
Lund, K1
Holdaas, H1
Fauchald, P1
Reisaeter, A1
Berg, KJ1
Bannister, KM1
Weaver, A1
Clarkson, AR1
Woodroffe, AJ1
Soni, PS1
Doifode, DV1
Kate, SK1
Ishimitsu, T1
Yagi, H1
Ohkubo, M1
Nakamura, Y1
Yagi, S1
Buzio, C2
Regolisti, G1
Perazzoli, F1
Mutti, A2
Bergamaschi, E1
Borghetti, A2
O'Donnell, MJ1
Rowe, BR1
Lawson, N1
Horton, A1
Gyde, OH1
Barnett, AH1
Wilkie, ME1
Beer, JC1
Raftery, MJ1
Dawnay, A1
Barton, C1
Marsh, FP1
Dworkin, LD2
Benstein, JA1
Parker, M2
Tolbert, E2
Feiner, HD2
Grekas, D1
Dioudis, C1
Kalevrosoglou, I1
Papoulidou, F1
Goutsaridis, N1
Alivanis, P1
Tourkantonis, A1
Garini, G1
Mazzi, A1
Allegri, L1
Savazzi, G1
Giordano, M1
Sanders, LR1
Castellino, P1
Canessa, ML1
DeFronzo, RA1
Yokoyama, H1
Tomonaga, O1
Hirayama, M1
Ishii, A1
Takeda, M1
Babazono, T1
Ujihara, U1
Takahashi, C1
Omori, Y1
Hess, B1
DeQuattro, V1
Lee, DP1
Kloke, HJ1
Wetzels, JF1
Koene, RA1
Huysmans, FT1
Smith, AC1
Toto, R1
Bakris, GL2
Mehrens, T1
Thiele, S1
Suwelack, B1
Kempkes, M1
Hohage, H1
Darlametsos, IE1
Papanikolaou, EN1
Varonos, DD1
Mackie, FE1
Meyer, TW1
Campbell, DJ1
Romero, R1
Salinas, I1
Lucas, A1
Teixidó, J1
Audi, L1
Sanmarti, A1
Ferder, L1
Daccordi, H1
Martello, M1
Panzalis, M1
Inserra, F1
Wang, L1
Wang, HY1
Tao, WY1
Demarie, BK1
Eliahou, HE1
Cohen, D1
Herzog, D1
Shechter, P1
Serban, I1
Kapuler, S1
Schiby, G1
Gavendo, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
THE EFFECTS OF SITAXSENTAN ONCE DAILY DOSING ON PROTEINURIA, 24-HOUR BLOOD PRESSURE, AND ARTERIAL STIFFNESS IN SUBJECTS WITH CHRONIC KIDNEY DISEASE[NCT00810732]Phase 227 participants (Actual)Interventional2007-05-09Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in Carotid-Femoral Pulse Wave Velocity (PWV) at Week 3 and 6

Carotid-femoral pulse wave velocity (PWV), a measure of arterial stiffness, is determined from the time taken for the arterial pulse to propagate from the carotid to the femoral artery. Baseline was defined as the pre-dose measurement for the measure collected at Week 0 of each treatment period. Week 3 and Week 6 was an average of measurement for the measure collected at Week 3 and 6 of each treatment period. (NCT00810732)
Timeframe: Baseline, Week 3 and 6

,,
InterventionMeter per second (Mean)
BaselineChange at Week 3Change at Week 6
Nifedipine7.94-0.21-0.38
Placebo7.74-0.210.29
Sitaxsentan7.97-0.19-0.41

Change From Baseline in Mean 24-Hour Urine Total Protein Level at Week 6

Mean urine total protein assessment included 24-hour urine collections to assess total protein excretion per 24 hours. Baseline was derived from an average of Week 0 (pre-dose) 24-hour urine collections prior to each treatment period. Week 6 was derived from an average of Week 6 24-hour urine collections for each treatment period. (NCT00810732)
Timeframe: Baseline, Week 6

,,
InterventionGrams per 24 hours (Mean)
BaselineChange at week 6
Nifedipine1.950.01
Placebo2.07-0.06
Sitaxsentan2.07-0.62

Change From Baseline in Mean Systemic Arterial Blood Pressure (BP), Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP) at Week 3 and 6

The 24-hour ambulatory BP monitoring was performed by using a BP cuff which was attached to the participant's arm, using the same arm throughout the study, with a small monitor that comfortably sits in the pocket of participant. Mean values over 24-hour measurements at each measurement period were calculated. The change in total 24-hour ambulatory monitoring of systemic arterial BP, SBP and DBP at Week 3 and 6 relative to baseline were reported. Baseline was as an average of the pre-dose measurement for the measure collected at Week 0 of each treatment period. Week 3 and Week 6 was an average of measurement for the measure collected at Week 3 and 6 of each treatment period. (NCT00810732)
Timeframe: Baseline, Week 3 and 6

,,
InterventionMillimeter of Mercury (mmHg) (Mean)
Mean Systemic Arterial BP: BaselineMean Systemic Arterial BP: Change at Week 3Mean Systemic Arterial BP: Change at Week 6Mean Systemic Arterial SBP :BaselineMean Systemic Arterial SBP: Change at Week 3Mean Systemic Arterial SBP: Change at Week 6Mean Systemic Arterial DBP: BaselineMean Systemic Arterial DBP: Change at Week 3Mean Systemic Arterial DBP: Change at Week 6
Nifedipine93.78-2.95-3.54125.12-4.20-4.4778.27-2.09-2.86
Placebo92.98-1.20-0.35125.17-2.81-1.5777.58-0.86-0.41
Sitaxsentan92.94-4.59-3.74124.03-4.88-3.9977.56-4.85-3.60

Reviews

1 review available for nifedipine and Proteinuria

ArticleYear
Hypertensive emergencies of pregnancy.
    Obstetrics and gynecology clinics of North America, 2013, Volume: 40, Issue:1

    Topics: Antihypertensive Agents; Calcium Channel Blockers; Creatine; Diuretics; Emergency Medicine; Female;

2013

Trials

16 trials available for nifedipine and Proteinuria

ArticleYear
Plasma pro-endothelin-1 peptide concentrations rise in chronic kidney disease and following selective endothelin A receptor antagonism.
    Journal of the American Heart Association, 2015, Mar-23, Volume: 4, Issue:3

    Topics: Adult; Biomarkers; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Double-Blind Method

2015
Blood pressure-independent reduction in proteinuria and arterial stiffness after acute endothelin-a receptor antagonism in chronic kidney disease.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:1

    Topics: Adult; Aged; Antihypertensive Agents; Arteries; Blood Pressure; Calcium Channel Blockers; Cross-Over

2009
Selective endothelin-A receptor antagonism reduces proteinuria, blood pressure, and arterial stiffness in chronic proteinuric kidney disease.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:4

    Topics: Adult; Antihypertensive Agents; Arteries; Blood Pressure; Cross-Over Studies; Double-Blind Method; D

2011
Endothelin-A receptor antagonism modifies cardiovascular risk factors in CKD.
    Journal of the American Society of Nephrology : JASN, 2013, Volume: 24, Issue:1

    Topics: Adult; Biomarkers; Blood Pressure; Cardiovascular Diseases; Cross-Over Studies; Double-Blind Method;

2013
Effect of angiotensin-converting enzyme and calcium channel inhibition on progression of IgA nephropathy.
    Contributions to nephrology, 1995, Volume: 111

    Topics: Aldosterone; Blood Pressure; Combined Modality Therapy; Diet, Sodium-Restricted; Disease Progression

1995
Renal effects of nifedipine and captopril in patients with essential hypertension and reduced renal reserve.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 24, Issue:6

    Topics: Adult; Captopril; Diuresis; Female; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; N

1994
Comparison of the effects of an angiotensin converting enzyme inhibitor and a calcium antagonist in hypertensive, macroproteinuric diabetic patients: a randomised double-blind study.
    Journal of human hypertension, 1993, Volume: 7, Issue:4

    Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel B

1993
Effect of nifedipine on renal haemodynamics and urinary protein excretion in stable renal transplant recipients.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 1

    Topics: Adult; Azathioprine; Blood Pressure; Creatinine; Cyclosporine; Female; Follow-Up Studies; Glomerular

1993
Effect of alpha-adrenergic blockers, ACE inhibitors, and calcium channel antagonists on renal function in hypertensive non-insulin-dependent diabetic patients.
    Nephron, 1996, Volume: 72, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood

1996
Predictors of the progression of diabetic nephropathy and the beneficial effect of angiotensin-converting enzyme inhibitors in NIDDM patients.
    Diabetologia, 1997, Volume: 40, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel B

1997
Equivalent reduction of proteinuria in hypertensives by either nifedipine GITS or enalapril: disparate effects on neurohormones and ambulatory blood pressure and the influence of salt.
    Cardiology, 1997, Volume: 88 Suppl 3

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Pressure Monitoring, Ambulator

1997
Effects of low-dose nifedipine on urinary protein excretion rate in patients with renal disease.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1998, Volume: 13, Issue:3

    Topics: Adult; beta 2-Microglobulin; Calcium Channel Blockers; Delayed-Action Preparations; Female; Glomerul

1998
Differential effects of calcium channel blockers on size selectivity of proteinuria in diabetic glomerulopathy.
    Kidney international, 1998, Volume: 54, Issue:3

    Topics: Adult; Aged; Calcium Channel Blockers; Diabetic Nephropathies; Diltiazem; Female; Humans; Kidney Glo

1998
Comparative effects of captopril versus nifedipine on proteinuria and renal function of type 2 diabetic patients.
    Diabetes research and clinical practice, 1992, Volume: 17, Issue:3

    Topics: Blood Glucose; Blood Pressure; Captopril; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glyc

1992
Angiotensin converting enzyme inhibitors versus calcium antagonists in the treatment of diabetic hypertensive patients.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:2 Suppl

    Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Creatinine; Diab

1992
Effects of different calcium antagonists on proteinuria associated with diabetes mellitus.
    Annals of internal medicine, 1990, Dec-15, Volume: 113, Issue:12

    Topics: Aged; Creatinine; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Di

1990

Other Studies

18 other studies available for nifedipine and Proteinuria

ArticleYear
Molecular basis of the counteraction by calcium channel blockers of cyclosporine nephrotoxicity.
    American journal of physiology. Renal physiology, 2018, 09-01, Volume: 315, Issue:3

    Topics: Animals; Biomarkers; Blood Urea Nitrogen; Calcium Channel Blockers; Collagen Type IV; Creatinine; Cy

2018
A 12-year-old boy with dyspnea, hypertension, hematuria, and proteinuria.
    Hospital pediatrics, 2015, Volume: 5, Issue:6

    Topics: Child; Diagnosis, Differential; Dyspnea; Furosemide; Glomerulonephritis; Hematuria; Humans; Hyperten

2015
Differential roles of dihydropyridine calcium antagonist nifedipine, nitrendipine and amlodipine on gentamicin-induced renal tubular toxicity in rats.
    European journal of pharmacology, 2009, Oct-12, Volume: 620, Issue:1-3

    Topics: Acetylglucosaminidase; Amlodipine; Animals; Apoptosis; bcl-2-Associated X Protein; Blood Urea Nitrog

2009
Differential effects of dihydropyridine calcium antagonists on doxorubicin-induced nephrotoxicity in rats.
    Toxicology, 2007, Feb-28, Volume: 231, Issue:1

    Topics: Amlodipine; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blood Urea Nitrogen; Calci

2007
Severe, early-onset hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome episode with spontaneous remission during pregnancy.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2007, Volume: 20, Issue:8

    Topics: Adult; Antihypertensive Agents; Female; Fetal Death; HELLP Syndrome; Humans; Methyldopa; Nifedipine;

2007
Contrasting short-term effects of nifedipine on glomerular and tubular functions in glomerulonephritic patients.
    Journal of the American Society of Nephrology : JASN, 1994, Volume: 5, Issue:6

    Topics: Adult; Aged; Albuminuria; Blood Pressure; Chronic Disease; Dextrans; Female; Glomerular Filtration R

1994
Proteinuria in essential hypertension.
    The Journal of the Association of Physicians of India, 1994, Volume: 42, Issue:5

    Topics: Adult; Aged; Colorimetry; Creatinine; Drug Combinations; Enalapril; Humans; Hypertension; Middle Age

1994
Different effects between antihypertensive drugs on nephrotic-range proteinuria in renovascular hypertension.
    American journal of nephrology, 1994, Volume: 14, Issue:1

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biso

1994
Calcium antagonists and converting enzyme inhibitors reduce renal injury by different mechanisms.
    Kidney international, 1993, Volume: 43, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Enalapril; Glomeruloscl

1993
Management of moderate to severe hypertension and proteinuria by nifedipine retard and perindopril after renal transplantation.
    Clinical nephrology, 1995, Volume: 44, Issue:5

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Creatinine; Delayed-Actio

1995
Renal effects of captopril, indomethacin and nifedipine in nephrotic patients after an oral protein load.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflam

1996
Reduced proteinuria after cessation of long-acting, osmotic release nifedipine GITS in diabetic nephropathy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1997, Volume: 12, Issue:8

    Topics: Aged; Calcium Channel Blockers; Delayed-Action Preparations; Diabetic Nephropathies; Female; Humans;

1997
The beneficial effects of calcium channel blockers on long-term kidney transplant survival are independent of blood-pressure reduction.
    Clinical transplantation, 2000, Volume: 14, Issue:3

    Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Creatinine; Follow-Up Studies; Gr

2000
Effect of nifedipine in cyclosporine-induced nephrotoxicity in rats: roles of the thromboxane and endothelin systems.
    Prostaglandins, leukotrienes, and essential fatty acids, 2000, Volume: 63, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Body Weight; Calcium Channel Blockers; Creatinine; Cyclospori

2000
Effects of antihypertensive therapy on intrarenal angiotensin and bradykinin levels in experimental renal insufficiency.
    Kidney international, 2002, Volume: 61, Issue:2

    Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Bradykin

2002
[The influence of hypertension and antihypertensive agents on experimental IgA nephropathy (IgAN)].
    Zhonghua nei ke za zhi, 1991, Volume: 30, Issue:9

    Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Female; Glomerulonephritis, IGA; Hypertension, R

1991
Effects of nifedipine and enalapril on glomerular structure and function in uninephrectomized SHR.
    Kidney international, 1991, Volume: 39, Issue:6

    Topics: Animals; Blood Pressure; Enalapril; Kidney Glomerulus; Longitudinal Studies; Nephrectomy; Nifedipine

1991
The control of hypertension and its effect on renal function in rat remnant kidney.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1988, Volume: 3, Issue:1

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Creatinine; Dietary Proteins; Dihydralazine; Fema

1988