nifedipine has been researched along with Pregnancy in 656 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated whether combined oral hydrochlorothiazide and lisinopril therapy produced superior short-term blood pressure control when compared with nifedipine among postpartum individuals with hypertension requiring pharmacologic treatment." | 9.69 | Oral combined hydrochlorothiazide and lisinopril vs nifedipine for postpartum hypertension: a comparative-effectiveness pilot randomized controlled trial. ( Amro, F; Blackwell, SC; Chauhan, SP; Fishel Bartal, M; Lawal, D; Pedroza, C; Samuel, J; Sibai, BM, 2023) |
| "To compare nifedipine, naproxen, or placebo for pain relief during diagnostic hysteroscopy." | 9.69 | Efficacy of Oral Nifedipine, Naproxen, or Placebo for Pain Relief During Diagnostic Hysteroscopy in an Office Setting: A Randomized Pilot Study. ( Emanuel, MH; Hamerlynck, T; Rombaut, J; van Wessel, S; Vanhulle, A; Weyers, S, 2023) |
| "The Giant PANDA study is a pragmatic, open-label, multicentre, randomised controlled trial of a treatment initiation strategy with nifedipine (calcium channel blocker), versus labetalol (mixed alpha/beta blocker) in 2300 women with pregnancy hypertension." | 9.69 | A treatment strategy with nifedipine versus labetalol for women with pregnancy hypertension: study protocol for a randomised controlled trial (Giant PANDA). ( Ashworth, D; Battersby, C; Bick, D; Chappell, LC; Green, M; Hardy, P; Leighton, L; Magee, LA; Maher, A; McManus, RJ; Moakes, C; Morris, RK; Myers, J; Nelson-Piercy, C; Rivero-Arias, O; Sparkes, J; Webb, A; Wilson, H, 2023) |
| "The purpose is to investigate the influence of nifedipine, labetalol, and magnesium sulfate on blood pressure control, blood coagulation, and maternal and infant outcome in those suffering from pregnancy-induced hypertension (PIH)." | 9.51 | Effects of Nifedipine and Labetalol Combined with Magnesium Sulfate on Blood Pressure Control, Blood Coagulation Function, and Maternal and Infant Outcome in Patients with Pregnancy-Induced Hypertension. ( Gu, S; Shao, Y; Zhang, X, 2022) |
| "To compare oral nifedipine and intravenous labetalol in the treatment of acute severe hypertension in pregnancy (SHP)." | 9.41 | Oral nifedipine may be a preferential option for treating acute severe hypertension during pregnancy: a meta-analysis. ( Cui, S; Ou, M; Yu, Y; Zhang, F; Zhao, S, 2023) |
| "To compare the change in cerebral perfusion pressure before and after intravenous labetalol vs oral nifedipine in the setting of acute severe hypertension in pregnancy." | 9.34 | Intravenous labetalol versus oral nifedipine for acute hypertension in pregnancy: effects on cerebral perfusion pressure. ( Belfort, MA; Clark, SL; Fox, KA; Sangi-Haghpeykar, H; Tolcher, MC, 2020) |
| "To assess the maternal and fetal outcome in women with mild to moderate chronic hypertension on antihypertensive drug (methyldopa or nifedipine) therapy compared to no medication." | 9.30 | Methyldopa versus nifedipine or no medication for treatment of chronic hypertension during pregnancy: A multicenter randomized clinical trial. ( Abdallah, S; Gaber, W; Gamal, A; Hamza, H; Marawan, H; Rezk, M; Salama, M, 2019) |
| "To assess the cost-effectiveness of treatment with nifedipine compared with atosiban in women with threatened preterm birth." | 9.30 | Cost effectiveness of nifedipine compared with atosiban in the treatment of threatened preterm birth (APOSTEL III trial). ( Bloemenkamp, K; de Boer, MA; Franx, A; Gyselaers, W; Kok, M; Mol, B; Nijman, T; Oudijk, MA; Porath, MM; Sueters, M; van Baaren, GJ; van Vliet, E; Woiski, M, 2019) |
| "To compare the efficacy of intravenous labetalol with oral nifedipine in the treatment of severe hypertension in pregnancy with blood pressure ≥160/110 mm Hg." | 9.30 | IV labetalol and oral nifedipine in acute control of severe hypertension in pregnancy-A randomized controlled trial. ( Sowjanya, R; Tatapudi, R; Zulfeen, M, 2019) |
| "Oral nifedipine is commonly used to treat pre-eclampsia, one of the most severe complications during pregnancy, but its clinical efficacy is less than ideal." | 9.27 | Epigallocatechin gallate enhances treatment efficacy of oral nifedipine against pregnancy-induced severe pre-eclampsia: A double-blind, randomized and placebo-controlled clinical study. ( Guo, JJ; Shi, DD; Wang, N; Zhou, L, 2018) |
| "To assess the impact of maintenance nifedipine therapy on pregnancy duration in women with preterm placenta previa bleeding." | 9.24 | Maintenance nifedipine therapy for preterm symptomatic placenta previa: A randomized, multicenter, double-blind, placebo-controlled trial. ( Benichou, J; Bubenheim, M; Chanavaz-Lacheray, I; de Vienne, C; Deruelle, P; Dreyfus, M; Muszynski, C; Verspyck, E, 2017) |
| "We sought to compare the efficacy of intravenously administered hydralazine and oral nifedipine for acute blood pressure control in acute hypertensive emergency of pregnancy." | 9.24 | Hydralazine vs nifedipine for acute hypertensive emergency in pregnancy: a randomized controlled trial. ( Gupta, A; Sharma, C; Soni, A; Verma, A; Verma, S, 2017) |
| "There is a lack of sufficient evidence regarding efficacy and safety of amlodipine on treating hypertension during pregnancy." | 9.22 | Nifedipine or amlodipine? The choice for hypertension during pregnancy: a systematic review and meta-analysis. ( Du, P; Mei, Z; Qin, S; Shi, S; Yin, J, 2022) |
| "This network meta-analysis aimed to compare the efficacy and safety of intravenous (IV) hydralazine, oral nifedipine, and IV labetalol with different dosage regimens in the treatment of severe hypertension during pregnancy." | 9.22 | Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials. ( Cheng, Y; Jiang, YF; Li, JB; Wu, HZ; Yu, D; Zhu, ZN, 2022) |
| " Methyldopa, labetalol, and nifedipine have been perceived safe to use during pregnancy and are therefore recommended in international guidelines for treatment of hypertension." | 9.22 | Pharmacokinetics of the most commonly used antihypertensive drugs throughout pregnancy methyldopa, labetalol, and nifedipine: a systematic review. ( Allegaert, K; Flint, RB; Mian, P; Schoenmakers, S; van de Vusse, D; Versmissen, J; Visser, W, 2022) |
| " Women with threatened preterm birth (gestational age 25-34 weeks) were randomly assigned (1:1) to either oral nifedipine or intravenous atosiban for 48 h." | 9.22 | Nifedipine versus atosiban for threatened preterm birth (APOSTEL III): a multicentre, randomised controlled trial. ( Bax, CJ; Beek, EV; Bloemenkamp, KWM; Duvekot, JJ; Franssen, MTM; Franx, A; Gyselaers, W; Heida, KY; Jacquemyn, Y; Kok, JH; Kok, M; Mol, BW; Nijman, TAJ; Opmeer, BC; Oudijk, MA; Papatsonis, DN; Porath, MM; Scheepers, HCJ; Schuit, E; van der Post, JAM; van Vliet, EOG; Woiski, M, 2016) |
| "In the present study, the efficacy and safety of oral nifedipine and intravenous labetalol for severe pre-eclampsia therapy were compared." | 9.22 | Oral nifedipine vs. intravenous labetalol for treatment of pregnancy-induced severe pre-eclampsia. ( Shi, DD; Wang, N; Yang, FZ; Zhou, L, 2016) |
| "To compare the effectiveness of orally administered nifedipine and intravenously administered labetalol for acute blood pressure control in hypertensive emergency of pregnancy." | 9.17 | Oral nifedipine or intravenous labetalol for hypertensive emergency in pregnancy: a randomized controlled trial. ( Sharma, C; Shekhar, S; Thakur, S; Verma, S, 2013) |
| "To compare oral nifedipine with intravenous labetalol in their rapidity to control hypertensive emergencies of pregnancy." | 9.16 | Oral nifedipine versus intravenous labetalol for acute blood pressure control in hypertensive emergencies of pregnancy: a randomised trial. ( Omar, SZ; Raheem, IA; Saaid, R; Tan, PC, 2012) |
| "Intravenous hydralazine is a commonly administered arteriolar vasodilator that is effective for hypertensive emergencies associated with pregnancy." | 9.15 | Comparison of the efficacy of nifedipine and hydralazine in hypertensive crisis in pregnancy. ( Esmaeili, S; Khazaeipour, Z; Motevalian, M; Pourmojieb, M; Rezaei, Z; Sharbaf, FR; Youefzadeh-Fard, Y, 2011) |
| "To compare the effectiveness, safety, and possible adverse effects of terbutaline and nifedipine in prolonging pregnancy beyond 48 h." | 9.13 | Terbutaline versus nifedipine for prolongation of pregnancy in patients with preterm labor. ( Duminy, P; Mawaldi, L; Tamim, H, 2008) |
| " administration of nitroglycerine as an antihypertensive agent in the management of pre-eclampsia is scarce." | 9.13 | Efficacy of nitroglycerine infusion versus sublingual nifedipine in severe pre-eclampsia: a randomized, triple-blind, controlled trial. ( Gordillo-Moscoso, A; Hernández-Sierra, JF; Mandeville, PB; Manzur-Verástegui, S; Rodríguez-Martínez, M, 2008) |
| "The purpose of this study was to determine whether the slower- and longer-acting nifedipine tablets were as effective and safe as the rapid onset and short-acting nifedipine capsules for the treatment of acute severe hypertension in pregnancy." | 9.10 | Efficacy and safety of nifedipine tablets for the acute treatment of severe hypertension in pregnancy. ( Brown, MA; Buddle, ML; Davis, GK; Farrell, T, 2002) |
| "Magnesium sulfate may prevent eclampsia by reducing cerebral vasoconstriction and ischemia." | 9.10 | A comparison of magnesium sulfate and nimodipine for the prevention of eclampsia. ( Allen, JC; Anthony, J; Belfort, MA; Saade, GR, 2003) |
| "Nifedipine is safe and more effective than hydralazine in controlling blood pressure in severe pre-eclampsia." | 9.10 | Nifedipine or hydralazine as a first-line agent to control hypertension in severe preeclampsia. ( Aali, BS; Nejad, SS, 2002) |
| "We sought to compare the efficacies of oral nifedipine and intravenous labetalol in the acute management of hypertensive emergencies of pregnancy." | 9.09 | A randomized, double-blind trial of oral nifedipine and intravenous labetalol in hypertensive emergencies of pregnancy. ( Chauhan, SP; Newman, RB; Scardo, JA; Vermillion, ST, 1999) |
| "Our purpose was to compare the hemodynamic effects of orally administered nifedipine and intravenously administered labetalol in preeclamptic hypertensive emergencies." | 9.09 | A randomized, double-blind, hemodynamic evaluation of nifedipine and labetalol in preeclamptic hypertensive emergencies. ( Chauhan, SP; Hogg, BB; Newman, RB; Scardo, JA; Vermillion, ST, 1999) |
| "To determine whether nifedipine or prazosin is the more appropriate second-line antihypertensive agent in pregnancy." | 9.09 | Nifedipine or prazosin as a second agent to control early severe hypertension in pregnancy: a randomised controlled trial. ( Hall, DR; Odendaal, HJ; Smith, M; Steyn, DW, 2000) |
| "The safety of use of the calcium channel blocker nifedipine in pregnancy as it affects child development has not been well evaluated." | 9.09 | Nifedipine administered in pregnancy: effect on the development of children at 18 months. ( Bortolus, R; Chatenoud, L; Parazzini, F; Ricci, E, 2000) |
| "To determine the efficacy of Nifedipine on postpartum blood Loss in patients with Pregnancy Induced Hypertension (PIH)." | 9.09 | [The effect of Nifedipine on postpartum blood loss in patients with pregnancy induced hypertension]. ( Liu, Y; Yang, X, 2000) |
| "To compare the effects of a single oral dose of nifedipine with those of intravenous dihydralazine on central haemodynamics in pregnant women with severe pre-eclampsia." | 9.08 | A comparison between the haemodynamic effects of oral nifedipine and intravenous dihydralazine in patients with severe pre-eclampsia. ( Visser, W; Wallenburg, HC, 1995) |
| "The purposes of this study were to compare the efficacy of sublingual nifedipine with intravenous hydrallazine in the control of acute hypertension of pregnancy and to make a preliminary assessment whether sublingual nifedipine could be recommended for use by midwives faced with severe hypertension in pregnancy in a rural setting." | 9.08 | Sublingual nifedipine compared with intravenous hydrallazine in the acute treatment of severe hypertension in pregnancy: potential for use in rural practice. ( Jegasothy, R; Paranthaman, S, 1996) |
| "To compare the effect of routine treatment with the calcium channel blocker nifedipine in mild to moderate hypertension in pregnancy." | 9.08 | Nifedipine versus expectant management in mild to moderate hypertension in pregnancy. Gruppo di Studio Ipertensione in Gravidanza. ( , 1998) |
| "To compare nifedipine (group 1) with methyldopa (group 2) in the management of pregnancy induced hypertension (PIH)." | 9.07 | A comparison of nifedipine with methyldopa in pregnancy induced hypertension. ( Jayawardana, J; Lekamge, N, 1994) |
| "The therapeutic effect of the calcium antagonist; Nifedipine was assessed in 30 patients with pre-eclampsia." | 9.07 | Evaluation of calcium-antagonist (Nifedipine) in the treatment of pre-eclampsia. ( Ismail, AA; Kholeif, A; Medhat, I; Tawfic, TA, 1993) |
| "The objective was to compare the fetal and maternal effects between parenteral hydralazine and sublingual nifedipine used like antihypertensive drugs in the management of severe preeclampsia." | 9.07 | [Management of severe pre-eclampsia/eclampsia. Comparison between nifedipine and hydralazine as antihypertensive agents]. ( Flores Padilla, LM; Walss Rodriguez, RJ, 1993) |
| "Thirty women with pregnancy-induced hypertension (PIH) scheduled for Caesarean section under general anaesthesia were studied to evaluate the efficacy of sublingual nifedipine in attenuating the pressor response to laryngoscopy and tracheal intubation." | 9.07 | Nifedipine attenuates the hypertensive response to tracheal intubation in pregnancy-induced hypertension. ( Bala, I; Batra, YK; Gopalan, S; Kumar, N, 1993) |
| "The objective of our study was to test the hypothesis that treatment with nifedipine for mild preeclampsia remote from term reduces the number of days of maternal hospitalization and improves pregnancy outcome." | 9.07 | A randomized prospective comparison of nifedipine and bed rest versus bed rest alone in the management of preeclampsia remote from term. ( Akl, S; Barton, JR; Mercer, BM; Sarinoglu, C; Sibai, BM, 1992) |
| "The effect of nifedipine (Adalat; Bayer-Miles)--a calcium channel blocker, which has a well-established place in nonobstetric hypertension--was compared with dihydralazine in 33 primigravidas with severe hypertension of pregnancy." | 9.06 | Nifedipine in acute hypertensive emergencies in pregnancy. ( Becker, P; Moodley, J; Seabe, SJ, 1989) |
| "The effect of nifedipine on uteroplacental blood flow was investigated in nine hypertensive women in the trimester of pregnancy and compared with the effects of a placebo in nine similar hypertensive women." | 9.06 | The effect of sublingual nifedipine on uteroplacental blood flow in hypertensive pregnancy. ( Davey, DA; Davies, N; Lindow, SW; Smith, JA, 1988) |
| "Oral nifedipine is recommended along with labetalol and hydralazine for treatment of severe hypertension during pregnancy by most authorities." | 8.93 | Oral nifedipine versus intravenous labetalol for severe hypertension during pregnancy: a systematic review and meta-analysis. ( Gupta, N; Kirubakaran, R; Pareek, P; Shekhar, S, 2016) |
| "The objective of this review was to assess the effects of magnesium sulphate compared with phenytoin when used for the care of women with eclampsia." | 8.86 | Magnesium sulphate versus phenytoin for eclampsia. ( Chou, D; Duley, L; Henderson-Smart, DJ, 2010) |
| "In this study, we presented 2 cases and evaluated the evidence for symptomatic hypocalcemia after treatment with magnesium sulfate alone or combined with use of nifedipine." | 8.82 | Symptomatic hypocalcemia after tocolytic therapy with magnesium sulfate and nifedipine. ( Friedman, SA; Koontz, SL; Schwartz, ML, 2004) |
| "Tradiational drug therapy choices for hypertension in pregnancy continue to be hydralazine for acute reduction of blood pressure and methyldopa for the management of chronic hypertension." | 8.79 | Use of nifedipine in the hypertensive diseases of pregnancy. ( Doering, PL; Hatton, RC; Levin, AC, 1994) |
| "To assess whether readmission for hypertension by 6 weeks postpartum differed between patients discharged on nifedipine or labetalol." | 8.12 | Postpartum Readmission for Hypertension After Discharge on Labetalol or Nifedipine. ( Do, SC; Druzin, ML; El-Sayed, YY; Girsen, AI; Herrero, T; Kan, P; Leonard, SA; Lyell, DJ; Panelli, DM, 2022) |
| "The results suggest that exposure to nifedipine in human pregnancy 3-4 weeks postfertilization may cause a direct effect on the embryonic heart resulting in reduced blood flow leading to abnormal heart and/or blood vessel development and/or embryonic death." | 7.91 | The effects of nifedipine and ivabradine on the functionality of the early rat embryonic heart. Are these drugs a risk in early human pregnancy? ( Gustaffson, E; Ritchie, HE; Telenius, C; Webster, WS, 2019) |
| "This first case report of gingival hyperplasia induced by nifedipine in pregnancy could be used as a reference for clinicians in the management of this adverse effect during the pregnancy." | 7.85 | Nifedipine Induced Gingival Hyperplasia in Pregnancy: A Case Report. ( Brochet, MS; Harry, M; Morin, F, 2017) |
| "This study examines the differential role of calcium signaling pathway(s) in histamine-induced uterotonic action during early and mid-pregnancy stages in buffaloes." | 7.85 | Extra and intracellular calcium signaling pathway(s) differentially regulate histamine-induced myometrial contractions during early and mid-pregnancy stages in buffaloes (Bubalus bubalis). ( Choudhury, S; Garg, SK; Nakade, UP; Sharma, A; Yadav, RS, 2017) |
| "Present study unravels the involvement of different calcium signaling pathways in oxytocin-induced contractions in myometrium of non-pregnant and pregnant buffaloes during early and mid-pregnancy stages." | 7.85 | Functional involvement of protein kinase C, Rho-kinase and TRPC3 decreases while PLC increases with advancement of pregnancy in mediating oxytocin-induced myometrial contractions in water buffaloes (Bubalus bubalis). ( Choudhury, S; Garg, SK; Nakade, UP; Sharma, A, 2017) |
| "To evaluate the risk of developing pulmonary edema in women exposed to nifedipine, magnesium sulfate (MgSO4), or both in a preterm setting." | 7.80 | Effect of magnesium sulfate and nifedipine on the risk of developing pulmonary edema in preterm births. ( Abenhaim, HA; Gangal, M; Xiao, C, 2014) |
| "Investigation of methyldopa and nifedipine effects on maternal and fetal hemodynamics in women with mild gestational hypertension during the third pregnancy trimester." | 7.78 | Effects of methyldopa and nifedipine on uteroplacental and fetal hemodynamics in gestational hypertension. ( Folic, MD; Folic, MM; Jankovic, SM; Varjacic, MR, 2012) |
| "A retrospective study in hypertensive patients treated during pregnancy with nifedipine or labetalol was conducted." | 7.78 | Nifedipine versus labetalol in the treatment of hypertensive disorders of pregnancy. ( Battistoni, GI; Bezzeccheri, V; Cecchi, L; Cecchi, S; Giannubilo, SR; Landi, B; Tranquilli, AL; Vitali, P, 2012) |
| "Alpha-methyldopa is a regularly used antihypertensive drug during pregnancy." | 7.76 | [Methyldopa-induced acute reactive hepatitis in pregnancy, drug-metabolizing capacity of the liver]. ( Monostory, K; Ozsvár, Z; Solymossi, Z, 2010) |
| "Study aim was assessment of clinical efficacy of mono therapy with nifedipine SR/GITS and combination of nifedipine SR/GITS and bisoprolol as well as investigation of functional state of sympathoadrenal system (SAS) in pregnant women with arterial hypertension." | 7.74 | [Clinical efficacy of antihypertensive therapy of pregnant women with arterial hypertension with long acting nifedipine and bisoprolol]. ( Brytkova, IaV; Bukhonkina, IuM; Pavlova, LN; Striuk, RI, 2008) |
| "A meta-analysis of randomized controlled trials suggests that nifedipine appears to be a reasonable agent for treatment of acute severe hypertension in pregnancy." | 7.73 | Nifedipine for severe hypertension in pregnancy: emotion or evidence? ( Côté, AM; Magee, LA; von Dadelszen, P, 2005) |
| " We report the first case of acute pulmonary edema following tocolytic oral nifedipine." | 7.73 | Acute pulmonary edema during tocolytic therapy with nifedipine. ( Abbas, OM; Kanj, NA; Nassar, AH; Usta, IM, 2006) |
| "Nifedipine was administered to 49 pregnant women with gestational hypertension as first-line therapy, and were longitudinally studied as paired observations for 3 or 10 day intervals of treatment with nifedipine until delivery." | 7.69 | The use of nifedipine as first-line hypotensive therapy in gestational hypertension. ( Caruso, A; De Carolis, MP; De Carolis, S; Ferrazzani, S; Mancinelli, S; Romano, D, 1994) |
| "A 34-year-old mother developed acute myocardial infarction (MI) 10 days postpartum while taking bromocriptine for ablactation." | 7.69 | Acute myocardial infarction in a healthy mother using bromocriptine for milk suppression. ( Hopp, L; Iffy, L; Weisse, AB, 1996) |
| "Our purpose was to evaluate the hemodynamic effects of oral nifedipine in preeclamptic hypertensive emergencies." | 7.69 | Hemodynamic effects of oral nifedipine in preeclamptic hypertensive emergencies. ( Hogg, BB; Newman, RB; Scardo, JA; Vermillion, ST, 1996) |
| "To investigate the effect of 7 to 14 days of therapy with nifedipine (sustained-release preparation) on the 24-hour blood pressure patterns of pregnant women with pre-eclampsia or chronic hypertension, and to test the utility of blood pressure monitoring in modulating the timing and dosage of the drug." | 7.69 | 24-hour blood pressure monitoring to evaluate the effects of nifedipine in pre-eclampsia and in chronic hypertension in pregnancy. ( Benedetto, C; Carandente, F; Chiarolini, L; Giarola, M; Maulà, V; Zonca, M, 1997) |
| "To study the effects of nifedipine on the microcirculation in pregnancy-induced hypertension (PIH)." | 7.69 | [The effect of nifedipine on the microcirculation in pregnancy-induced hypertension]. ( Hao, C; Li, F; Yu, X, 1996) |
| " Description of their management, usage of nifedipine, and pregnancy outcome." | 7.69 | Sublingual nifedipine in human pregnancy. ( Gallery, ED; Györy, AZ, 1997) |
| "To examine the efficacy of magnesium sulfate (MgSO4) as an anticonvulsant in eclampsia and imminent eclampsia." | 7.69 | Magnesium sulfate as an anticonvulsant in eclampsia. ( Raman, NV; Rao, CA, 1995) |
| "Although the calcium antagonist nifedipine has been reported to suppress preterm labor, little is known of the effects of long-term nifedipine use in late pregnancy." | 7.68 | The effects of nifedipine on pregnancy outcome and morphology of the placenta, uterus, and cervix during late pregnancy in the rat. ( Richichi, J; Vasilenko, P, 1992) |
| "The pharmacokinetics of oral nifedipine were studied in 15 women with pregnancy-induced hypertension in the third trimester of pregnancy to determine if the drug's disposition was different from that in nonpregnant patients." | 7.68 | Oral nifedipine pharmacokinetics in pregnancy-induced hypertension. ( Akl, SA; Prevost, RR; Sibai, BM; Whybrew, WD, 1992) |
| "The short-term effect of 20 mg of oral nifedipine on maternal and fetal hemodynamics was investigated in 12 women with pregnancy-induced hypertension." | 7.68 | Uterine and fetal flow velocity waveforms in hypertensive pregnancy: the effect of a single dose of nifedipine. ( Ekblad, UU; Erkkola, RU; Pirhonen, JP, 1990) |
| "The case is reported of successful conception and pregnancy in a woman with systemic sclerosis while receiving continuous treatment with nifedipine 30 mg/day, after a previously poor obstetric record and involuntary secondary infertility." | 7.68 | Successful pregnancy in a woman with systemic sclerosis while taking nifedipine. ( Kirby, JD; Wilson, AG, 1990) |
| "The effect of lowering the maternal blood pressure with sublingual nifedipine on the fetal heart rate was studied in 51 patients with severe pregnancy-induced hypertension." | 7.68 | Effect of nifedipine on fetal heart rate in the treatment of severe pregnancy-induced hypertension. ( Fenakel, K; Friedman, A; Lurie, S, 1990) |
| "The calcium antagonist, nifedipine, was given orally to 21 women with acute episodes of severe hypertension during pregnancy or in the puerperium." | 7.67 | Treatment of severe pregnancy-associated hypertension with the calcium antagonist nifedipine. ( Redman, CW; Walters, BN, 1984) |
| "Slow-release nifedipine has been used in the treatment of severe hypertension in 23 pregnant women." | 7.67 | Nifedipine as a second line antihypertensive drug in pregnancy. ( Beevers, DG; Constantine, G; Luesley, DM; Reynolds, AL, 1987) |
| "Preeclampsia is associated with maternal and perinatal morbidity." | 7.30 | Trial of Intrapartum Extended-Release Nifedipine to Prevent Severe Hypertension Among Pregnant Individuals With Preeclampsia With Severe Features. ( Cleary, EM; Costantine, MM; Kudrimoti, M; Patton, KG; Racchi, NW; Rood, KM, 2023) |
| "Preterm birth is the most common cause of neonatal morbidity and mortality." | 7.01 | The effectiveness of nifedipine/indomethacin combination therapy and nifedipine monotherapy for postponing preterm birth (25-34 weeks of gestation) in Sudanese women: a randomized clinical trial study protocol. ( Abdelrahiem, SK; Adam, I; Elfaki, T; Elhassan, EM; Ibrahim, MH, 2021) |
| " Hence, the data suggest gastroretention as a promising approach to enhance bioavailability of nifedipine." | 6.90 | Formulation, Optimization, and In vivo Evaluation of Gastroretentive Drug Delivery System of Nifedipine for the Treatment of Preeclampsia. ( Avari, JG; Karemore, MN, 2019) |
| "A total of 626 patients with preeclampsia were enrolled, screened, and assigned by random to groups receiving either nifedipine + placebo or nifedipine + celastrol orally." | 6.84 | Celastrol synergizes with oral nifedipine to attenuate hypertension in preeclampsia: a randomized, placebo-controlled, and double blinded trial. ( Liang, Y; Wang, D; Xiao, S; Zhang, M, 2017) |
| "Nifedipine was found to be more effective than other antihypertensive medications to reduce blood pressure, particularly in patients with severe hypertension." | 6.82 | Comparative efficacy and safety of oral nifedipine with other antihypertensive medications in the management of hypertensive disorders of pregnancy: a systematic review and meta-analysis of randomized controlled trials. ( Adela, R; George, R; Joy, CA; Thomas, C; Undela, K; Varghese, B, 2022) |
| "In nifedipine-treated non-pregnant controls, only EC80 for adrenaline-induced aggregation decreased." | 6.68 | Nifedipine reduces thromboxane A2 production by platelets without changing aggregation in hypertensive pregnancy. ( Manninen, A, 1996) |
| "One hundred forty-eight women with mild preeclampsia were randomly allocated to treatment with either bed rest alone (n=64) or in combination with nifedipine (n=84) at 26-36 weeks' gestation." | 6.68 | The effect of nifedipine on urinary excretion of calcium in preeclampsia. ( Barton, JR; Mercer, BM; Sibai, BM, 1997) |
| "The patients with preeclampsia undergoing emergent cesarean section is always a challenge to an anesthesiologist, because severe hypertensive response after laryngoscopy and tracheal intubation may result in life-threatening complication such as cerebral hemorrhage." | 6.67 | [Nifedipine in preeclampsia for cesarean section]. ( Chen, JC; Hong, YJ; Lin, CF; Pan, P; Wei, TT; Wong, KL, 1993) |
| "Nifedipine is a calcium channel blocker that reduces blood pressure and increases renal blood flow." | 6.67 | The use of nifedipine during the postpartum period in patients with severe preeclampsia. ( Barton, JR; Conover, WB; Hiett, AK, 1990) |
| "Nifedipine treatment did not reduce gene expression or protein secretion of pro-inflammatory cytokines in either cultured myometrial cells or ex vivo tissues." | 5.91 | Assessment of the tocolytic nifedipine in preclinical primary models of preterm birth. ( Arman, BM; Beard, S; Binder, NK; de Alwis, N; Debruin, DA; Hannan, NJ; Hayes, A; Kaitu'u-Lino, TJ; Tong, S, 2023) |
| " Therapy success: systolic blood pressure ~140 mm Hg and diastolic blood pressure ~90 mm Hg, therapy failure: persistent systolic blood pressure ≥ 160 or diastolic blood pressure ≥ 110 mm Hg after maximum dosage of therapy (EL)." | 5.91 | Comparison of outcomes following intravenous magnesium compared with intravenous labetalol and oral nifedipine in 355 pregnant Han Chinese women with preeclampsia. ( Dong, W; Peng, Z; Xiao, Y; Zhang, J, 2023) |
| "We evaluated whether combined oral hydrochlorothiazide and lisinopril therapy produced superior short-term blood pressure control when compared with nifedipine among postpartum individuals with hypertension requiring pharmacologic treatment." | 5.69 | Oral combined hydrochlorothiazide and lisinopril vs nifedipine for postpartum hypertension: a comparative-effectiveness pilot randomized controlled trial. ( Amro, F; Blackwell, SC; Chauhan, SP; Fishel Bartal, M; Lawal, D; Pedroza, C; Samuel, J; Sibai, BM, 2023) |
| "To compare nifedipine, naproxen, or placebo for pain relief during diagnostic hysteroscopy." | 5.69 | Efficacy of Oral Nifedipine, Naproxen, or Placebo for Pain Relief During Diagnostic Hysteroscopy in an Office Setting: A Randomized Pilot Study. ( Emanuel, MH; Hamerlynck, T; Rombaut, J; van Wessel, S; Vanhulle, A; Weyers, S, 2023) |
| "The Giant PANDA study is a pragmatic, open-label, multicentre, randomised controlled trial of a treatment initiation strategy with nifedipine (calcium channel blocker), versus labetalol (mixed alpha/beta blocker) in 2300 women with pregnancy hypertension." | 5.69 | A treatment strategy with nifedipine versus labetalol for women with pregnancy hypertension: study protocol for a randomised controlled trial (Giant PANDA). ( Ashworth, D; Battersby, C; Bick, D; Chappell, LC; Green, M; Hardy, P; Leighton, L; Magee, LA; Maher, A; McManus, RJ; Moakes, C; Morris, RK; Myers, J; Nelson-Piercy, C; Rivero-Arias, O; Sparkes, J; Webb, A; Wilson, H, 2023) |
| "This study aimed to determine if enalapril is superior to nifedipine in preventing prolonged hospitalizations, unplanned medical visits, and/or readmission among women with postpartum hypertension." | 5.69 | A randomized controlled trial comparing the efficacy of nifedipine and enalapril in the postpartum period. ( Celi, AC; McElrath, TF; Robinson, JN; Seely, EW; Yoselevsky, EM, 2023) |
| "To explore the regulatory effect of magnesium sulfate combined with nifedipine and labetalol on disease-related molecules in serum and placenta in the treatment of preeclampsia." | 5.56 | Regulation of magnesium sulfate combined with nifedipine and labetalol on disease-related molecules in serum and placenta in the treatment of preeclampsia. ( Wang, DJ; Wu, Y; Zhang, R; Zhang, Y; Zhang, YX, 2020) |
| "The purpose is to investigate the influence of nifedipine, labetalol, and magnesium sulfate on blood pressure control, blood coagulation, and maternal and infant outcome in those suffering from pregnancy-induced hypertension (PIH)." | 5.51 | Effects of Nifedipine and Labetalol Combined with Magnesium Sulfate on Blood Pressure Control, Blood Coagulation Function, and Maternal and Infant Outcome in Patients with Pregnancy-Induced Hypertension. ( Gu, S; Shao, Y; Zhang, X, 2022) |
| "In 14 patients with preeclampsia, 55 hypertensive emergencies were identified (BP >150/95)." | 5.46 | A trial of oral nifedipine and oral labetalol in preeclampsia hypertensive emergency treatment. ( Arjona-Berral, JE; Castelo-Branco, C; Duro-Gómez, J; Duro-Gómez, L; Giménez de Azcárete, M; Hernández-Angeles, C; Rodríguez-Marín, AB, 2017) |
| "Women with preeclampsia have elevated levels of inflammatory cytokines including IL-6." | 5.42 | The reduction of circulating levels of IL-6 in pregnant women with preeclampsia by magnesium sulphate and nifedipine: In vitro evidence for potential mechanisms. ( Chamley, LW; Chen, Q; Guo, F; Stone, PR; Xiao, JP; Yin, YX; Zhao, M, 2015) |
| "Totally 704 preeclampsia patients were randomly assigned to the treatment group and the control group, 352 cases in each group." | 5.42 | [Effect of Magnesium Sulfate, Nifedipine Tablet Combined Salvia Injection on ET-1/NO, TXA2/PGI2 and Hemorheology of Preeclampsia Patients]. ( Li, M; Qiu, SQ; Yao, J; Zhang, M; Zheng, XY; Zhu, JM; Zhu, ZX, 2015) |
| "To compare oral nifedipine and intravenous labetalol in the treatment of acute severe hypertension in pregnancy (SHP)." | 5.41 | Oral nifedipine may be a preferential option for treating acute severe hypertension during pregnancy: a meta-analysis. ( Cui, S; Ou, M; Yu, Y; Zhang, F; Zhao, S, 2023) |
| "This was a randomized, double-blind, placebo-controlled trial of nifedipine in women with a singleton pregnancy between 28 0/7 and 33 6/7 weeks of gestation who were admitted with uterine activity, intact membranes, and cervical dilatation from 2 to 4 cm." | 5.41 | Nifedipine for Acute Tocolysis of Preterm Labor: A Placebo-Controlled Randomized Trial. ( Casey, BM; Hawkins, JS; Leveno, KJ; McIntire, DD; Wells, CE, 2021) |
| " Moreover, as the combination did not cause severe maternal side effects, it may be considered as a safe and effective method to prolong gestation in patients with preterm labor." | 5.40 | The influence of ritodrine alone or in combination with nifedipine on maternal cardiovascular side effects and pregnancy outcomes. ( Bae, JY; Hwang, I; Kim, MJ; Seong, WJ, 2014) |
| "Risk factors for preterm labor commonly observed in the study group were urinary tract infection (60." | 5.39 | Pregnancy outcomes and successful rate of nifedipine therapeutic protocol implementation in a hospital of San Juan. ( Catalano, LN; Negron, I; Rivera Rosa, E; Vázquez Guzmán, M; Villar Diaz, M, 2013) |
| "Nifedipine was associated with a minimal but significant decrease in blood pressure." | 5.37 | Hypotension in normotensive pregnant women treated with nifedipine as a tocolytic drug. ( Luewan, S; Mahathep, R; Tongsong, T, 2011) |
| "The APOSTEL III trial was a multicentre randomised controlled trial that compared tocolysis with nifedipine or atosiban in 503 women with threatened preterm birth." | 5.34 | Effects of tocolysis with nifedipine or atosiban on child outcome: follow-up of the APOSTEL III trial. ( Kleinrouweler, CE; Klumper, J; Mol, BW; Naaktgeboren, CA; Nijman, TA; Oudijk, MA; Pajkrt, E; Roos, C; Roseboom, TJ; Tichelaar, MA; van Baar, AL; van Wassenaer-Leemhuis, AG; van Winden, T; Van't Hooft, J, 2020) |
| "To compare the change in cerebral perfusion pressure before and after intravenous labetalol vs oral nifedipine in the setting of acute severe hypertension in pregnancy." | 5.34 | Intravenous labetalol versus oral nifedipine for acute hypertension in pregnancy: effects on cerebral perfusion pressure. ( Belfort, MA; Clark, SL; Fox, KA; Sangi-Haghpeykar, H; Tolcher, MC, 2020) |
| "The use of labetalol and nifedipine were not related to any significant changes in maternal Doppler, which is reassuring about the safety of these drugs when treating acute severe hypertension in pregnancy." | 5.34 | To study the changes in maternal hemodynamics with intravenous labetalol or nifedipine in acute severe hypertension. ( Gainder, S; Prakash, M; Saha, SC; Thakur, M, 2020) |
| "The cases had more severe preeclampsia and a longer magnesium sulfate infusion." | 5.33 | Therapy with both magnesium sulfate and nifedipine does not increase the risk of serious magnesium-related maternal side effects in women with preeclampsia. ( Carleton, B; Cheng, C; Côté, AM; Ensom, MH; Li, J; Magee, LA; Miremadi, S; von Dadelszen, P, 2005) |
| "To assess the maternal and fetal outcome in women with mild to moderate chronic hypertension on antihypertensive drug (methyldopa or nifedipine) therapy compared to no medication." | 5.30 | Methyldopa versus nifedipine or no medication for treatment of chronic hypertension during pregnancy: A multicenter randomized clinical trial. ( Abdallah, S; Gaber, W; Gamal, A; Hamza, H; Marawan, H; Rezk, M; Salama, M, 2019) |
| "This was a nested cohort study of women with chronic hypertension and a singleton pregnancy recruited to the PANDA (Pregnancy And chronic hypertension: NifeDipine vs lAbetalol as antihypertensive treatment) study at one of three UK maternity units." | 5.30 | Longitudinal changes in vascular function parameters in pregnant women with chronic hypertension and association with adverse outcome: a cohort study. ( Chappell, LC; Cruickshank, JK; Khalil, A; Mills, C; Myers, JE; Nelson-Piercy, C; Seed, PT; Watt-Coote, I; Webster, LM, 2019) |
| "To assess the cost-effectiveness of treatment with nifedipine compared with atosiban in women with threatened preterm birth." | 5.30 | Cost effectiveness of nifedipine compared with atosiban in the treatment of threatened preterm birth (APOSTEL III trial). ( Bloemenkamp, K; de Boer, MA; Franx, A; Gyselaers, W; Kok, M; Mol, B; Nijman, T; Oudijk, MA; Porath, MM; Sueters, M; van Baaren, GJ; van Vliet, E; Woiski, M, 2019) |
| "This double blinded, randomized, and placebo-controlled trial demonstrated that the single use of 20 mg nifedipine given 30 minutes before embryo transfer did not improve the implantation rate or the clinical pregnancy rate of the infertility treatment." | 5.30 | Does nifedipine improve outcomes of embryo transfer?: Interim analysis of a randomized, double blinded, placebo-controlled trial. ( Agresta, F; Ng, KKL; Polyakov, A; Rozen, G; Stewart, T, 2019) |
| "The use of labetalol and nifedipine were not related to any significant changes in fetal Doppler, which is reassuring about the safety of these drugs when treating acute severe hypertension in pregnancy." | 5.30 | To study the changes in fetal hemodynamics with intravenous labetalol or nifedipine in acute severe hypertension. ( Gainder, S; Prakash, M; Saha, SC; Thakur, M, 2019) |
| "To compare the efficacy of intravenous labetalol with oral nifedipine in the treatment of severe hypertension in pregnancy with blood pressure ≥160/110 mm Hg." | 5.30 | IV labetalol and oral nifedipine in acute control of severe hypertension in pregnancy-A randomized controlled trial. ( Sowjanya, R; Tatapudi, R; Zulfeen, M, 2019) |
| "Also, patients with superimposed preeclampsia were treated with 40 mg/day oral nifedipine." | 5.28 | Nifedipine treatment in preeclampsia reverts the increased erythrocyte aggregation to normal. ( Boemi, M; De Tommaso, G; Fumelli, P; Garzetti, GG; Lucino, E; Romanini, C; Tranquilli, AL, 1992) |
| "Pharmacokinetic and pharmacodynamic parameters of oral nifedipine were studied in the immediate postpartum period in eight women with preeclampsia." | 5.28 | Nifedipine pharmacokinetics and pharmacodynamics during the immediate postpartum period in patients with preeclampsia. ( Barton, JR; Prevost, RR; Sibai, BM; Whybrew, WD; Wilson, DA, 1991) |
| "Twenty patients with preeclampsia at a gestational age of 26 to 35 weeks were treated with oral nifedipine until delivery." | 5.28 | The effect of nifedipine therapy on fetal and placental Doppler waveforms in preeclampsia remote from term. ( Akl, S; Fairlie, FM; Khoury, AD; Moretti, MM; Sibai, BM, 1990) |
| " The aim of this study was to evaluate whether tocolysis with nifedipine or atosiban in women with threatened preterm birth can reduce the incidence of overall brain injury in neonates born prematurely." | 5.27 | Effect of nifedipine and atosiban on perinatal brain injury: secondary analysis of the APOSTEL-III trial. ( Benders, MJN; de Haan, TR; Franx, A; Goedhart, MM; Mol, BW; Naaktgeboren, CN; Nijman, TAJ; Oudijk, MA; Vijlbrief, DC, 2018) |
| "Oral nifedipine is commonly used to treat pre-eclampsia, one of the most severe complications during pregnancy, but its clinical efficacy is less than ideal." | 5.27 | Epigallocatechin gallate enhances treatment efficacy of oral nifedipine against pregnancy-induced severe pre-eclampsia: A double-blind, randomized and placebo-controlled clinical study. ( Guo, JJ; Shi, DD; Wang, N; Zhou, L, 2018) |
| "Two women with preeclampsia treated unsuccessfully with alpha-methyldopa and magnesium sulfate became profoundly hypotensive when oral nifedipine was added." | 5.27 | Magnesium plus nifedipine: potentiation of hypotensive effect in preeclampsia? ( Cámera, MI; Martinotti, A; Mayorga, LM; Vignolo, CA; Waisman, GD, 1988) |
| "To assess the impact of maintenance nifedipine therapy on pregnancy duration in women with preterm placenta previa bleeding." | 5.24 | Maintenance nifedipine therapy for preterm symptomatic placenta previa: A randomized, multicenter, double-blind, placebo-controlled trial. ( Benichou, J; Bubenheim, M; Chanavaz-Lacheray, I; de Vienne, C; Deruelle, P; Dreyfus, M; Muszynski, C; Verspyck, E, 2017) |
| "We sought to compare the efficacy of intravenously administered hydralazine and oral nifedipine for acute blood pressure control in acute hypertensive emergency of pregnancy." | 5.24 | Hydralazine vs nifedipine for acute hypertensive emergency in pregnancy: a randomized controlled trial. ( Gupta, A; Sharma, C; Soni, A; Verma, A; Verma, S, 2017) |
| "Nifedipine may be better for delayed delivery and less likely to produce adverse pregnancy outcomes, followed by indomethacin." | 5.22 | Four kinds of tocolytic therapy for preterm delivery: Systematic review and network meta-analysis. ( Pei, S; Xiong, Z; Zhu, Z, 2022) |
| "There is a lack of sufficient evidence regarding efficacy and safety of amlodipine on treating hypertension during pregnancy." | 5.22 | Nifedipine or amlodipine? The choice for hypertension during pregnancy: a systematic review and meta-analysis. ( Du, P; Mei, Z; Qin, S; Shi, S; Yin, J, 2022) |
| "This network meta-analysis aimed to compare the efficacy and safety of intravenous (IV) hydralazine, oral nifedipine, and IV labetalol with different dosage regimens in the treatment of severe hypertension during pregnancy." | 5.22 | Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials. ( Cheng, Y; Jiang, YF; Li, JB; Wu, HZ; Yu, D; Zhu, ZN, 2022) |
| "Worldwide, nifedipine and atosiban are the two most commonly used tocolytic agents for the treatment of threatened preterm birth." | 5.22 | Tocolysis with nifedipine versus atosiban and perinatal outcome: an individual participant data meta-analysis. ( Al-Omari, WR; Kashanian, M; Kleinrouweler, CE; Mol, BW; Nijman, TAJ; Oudijk, MA; Pajkrt, E; Roos, C; Salim, R; van Winden, TMS, 2022) |
| " Methyldopa, labetalol, and nifedipine have been perceived safe to use during pregnancy and are therefore recommended in international guidelines for treatment of hypertension." | 5.22 | Pharmacokinetics of the most commonly used antihypertensive drugs throughout pregnancy methyldopa, labetalol, and nifedipine: a systematic review. ( Allegaert, K; Flint, RB; Mian, P; Schoenmakers, S; van de Vusse, D; Versmissen, J; Visser, W, 2022) |
| " Women with threatened preterm birth (gestational age 25-34 weeks) were randomly assigned (1:1) to either oral nifedipine or intravenous atosiban for 48 h." | 5.22 | Nifedipine versus atosiban for threatened preterm birth (APOSTEL III): a multicentre, randomised controlled trial. ( Bax, CJ; Beek, EV; Bloemenkamp, KWM; Duvekot, JJ; Franssen, MTM; Franx, A; Gyselaers, W; Heida, KY; Jacquemyn, Y; Kok, JH; Kok, M; Mol, BW; Nijman, TAJ; Opmeer, BC; Oudijk, MA; Papatsonis, DN; Porath, MM; Scheepers, HCJ; Schuit, E; van der Post, JAM; van Vliet, EOG; Woiski, M, 2016) |
| " The aim of this trial was to study the effect of prolonged tocolysis with nifedipine versus placebo in women with PPROM on perinatal outcome and prolongation of pregnancy." | 5.22 | Nifedipine versus placebo in the treatment of preterm prelabor rupture of membranes: a randomized controlled trial: Assessment of perinatal outcome by use of tocolysis in early labor-APOSTEL IV trial. ( Bax, CJ; Bloemenkamp, KW; de Lange, TS; Franx, A; Kok, M; Mol, BW; Naaktgeboren, CA; Nijman, TA; Oude Rengerink, K; Oudijk, MA; Scheepers, HC; van Eyck, J; van Vliet, EO; Woiski, M, 2016) |
| "In the present study, the efficacy and safety of oral nifedipine and intravenous labetalol for severe pre-eclampsia therapy were compared." | 5.22 | Oral nifedipine vs. intravenous labetalol for treatment of pregnancy-induced severe pre-eclampsia. ( Shi, DD; Wang, N; Yang, FZ; Zhou, L, 2016) |
| "Our objective is to compare the efficacy of combination regimen (salbutamol and nifedipine) against single regimen (nifedipine alone) in preventing preterm births among women with preterm labor." | 5.20 | Single versus combination tocolytic regimen in the prevention of preterm births in women: a prospective cohort study. ( Abdul Rahman, MF; Chee, JJ; Lim, ML; Ng, QJ; Tan, KH, 2015) |
| " The study was designed to establish a correlation between body weight and nifedipine plasma level." | 5.20 | Pharmacokinetics of nifedipine slow-release during sustained tocolysis. ( Kwee, A; Lotgering, FK; Mol, BW; Papatsonis, DN; Porath, MM; Roos, C; Spaanderman, ME; ter Laak, MA; Touw, DJ; van 't Veer, NE; van der Post, JA; van Hattum, PR; van Pampus, MG, 2015) |
| "The aim of our study was to compare the efficacy and safety of nifedipine and progesterone for maintenance tocolysis after arrested preterm labour, in prolonging pregnancy and preventing recurrence of preterm labour." | 5.19 | Comparison of nifedipine and progesterone for maintenance tocolysis after arrested preterm labour. ( Kamat, S; Rani, R; Veena, P, 2014) |
| "Women with a singleton pregnancy in threatened preterm labour (24(+0) to 33(+6) weeks) with a positive fetal fibronectin test were randomised to nifedipine or placebo." | 5.19 | The NIFTY study: a multicentre randomised double-blind placebo-controlled trial of nifedipine maintenance tocolysis in fetal fibronectin-positive women in threatened preterm labour. ( Hayward, L; McCowan, L; Mol, BW; Parry, E; Roos, C; Stone, P, 2014) |
| " This multicenter randomised clinical trial aims to compare nifedipine and atosiban in terms of neonatal outcome, duration of pregnancy and maternal side effects." | 5.19 | Nifedipine versus atosiban in the treatment of threatened preterm labour (Assessment of Perinatal Outcome after Specific Tocolysis in Early Labour: APOSTEL III-Trial). ( Bax, CJ; Bijvank, BN; Bloemenkamp, KW; Duvekot, HJ; Franssen, MT; Franx, A; Gyselaers, W; Heida, KY; Jaquemyn, Y; Kok, JH; Kok, M; Mol, BW; Opmeer, BC; Oudijk, MA; Porath, MM; Scheepers, HC; Schuit, E; van Beek, E; van Vliet, EO; Woiski, M, 2014) |
| "To compare the effectiveness of orally administered nifedipine and intravenously administered labetalol for acute blood pressure control in hypertensive emergency of pregnancy." | 5.17 | Oral nifedipine or intravenous labetalol for hypertensive emergency in pregnancy: a randomized controlled trial. ( Sharma, C; Shekhar, S; Thakur, S; Verma, S, 2013) |
| "To compare oral nifedipine with intravenous labetalol in their rapidity to control hypertensive emergencies of pregnancy." | 5.16 | Oral nifedipine versus intravenous labetalol for acute blood pressure control in hypertensive emergencies of pregnancy: a randomised trial. ( Omar, SZ; Raheem, IA; Saaid, R; Tan, PC, 2012) |
| " The treatment regimen included use of nifedipine as an antihypertensive, magnesium sulfate as an anticonvulsant, rapid interruption of pregnancy, and admission to the ICU." | 5.16 | Management of eclampsia at Assiut University Hospital, Egypt. ( Abd El Aal, DE; Shahin, AY, 2012) |
| "Intravenous hydralazine is a commonly administered arteriolar vasodilator that is effective for hypertensive emergencies associated with pregnancy." | 5.15 | Comparison of the efficacy of nifedipine and hydralazine in hypertensive crisis in pregnancy. ( Esmaeili, S; Khazaeipour, Z; Motevalian, M; Pourmojieb, M; Rezaei, Z; Sharbaf, FR; Youefzadeh-Fard, Y, 2011) |
| "We examined pregnancy outcomes in women receiving nifedipine tocolysis having recurrent preterm labor (RPTL)." | 5.14 | An examination of the clinical benefits and cost-effectiveness of tocolytic replacement following recurrent preterm labor. ( de la Torre, L; Desch, C; Flick, AA; González-Quintero, VH; Istwan, N; Rhea, D; Roca, LE, 2010) |
| "To estimate the effectiveness of nifedipine as a uterine relaxant during external cephalic version to correct breech presentation." | 5.13 | Nifedipine as a uterine relaxant for external cephalic version: a randomized controlled trial. ( Bais, JM; Doornbos, JP; Hanny, D; Kleiverda, G; Kok, M; Mol, BW; Papatsonis, DM; van der Post, JA; van Lith, JM, 2008) |
| "When compared with placebo, maintenance nifedipine tocolysis did not confer a large reduction in preterm birth or improvement in neonatal outcomes." | 5.13 | Maintenance nifedipine tocolysis compared with placebo: a randomized controlled trial. ( Caughey, AB; Chitkara, U; Druzin, ML; El-Sayed, YY; Lyell, DJ; Mannan, J; Pullen, KM, 2008) |
| "To compare the effectiveness, safety, and possible adverse effects of terbutaline and nifedipine in prolonging pregnancy beyond 48 h." | 5.13 | Terbutaline versus nifedipine for prolongation of pregnancy in patients with preterm labor. ( Duminy, P; Mawaldi, L; Tamim, H, 2008) |
| " administration of nitroglycerine as an antihypertensive agent in the management of pre-eclampsia is scarce." | 5.13 | Efficacy of nitroglycerine infusion versus sublingual nifedipine in severe pre-eclampsia: a randomized, triple-blind, controlled trial. ( Gordillo-Moscoso, A; Hernández-Sierra, JF; Mandeville, PB; Manzur-Verástegui, S; Rodríguez-Martínez, M, 2008) |
| "This review (1) summarizes currently recommended medications and dosing strategies for non-emergent HDP treatment, (2) reviews and synthesizes existing literature identified via a comprehensive PubMed search evaluating gestational changes in the maternal pharmacokinetics of commonly prescribed HDP drugs (notably labetalol and nifedipine), and (3) offers insight into the metabolism and clearance mechanisms underlying altered HDP drug pharmacokinetics during pregnancy." | 5.12 | The Impact of Pregnancy on Antihypertensive Drug Metabolism and Pharmacokinetics: Current Status and Future Directions. ( Daubert, MA; Fashe, MM; Garcia, JE; Lee, CR; Loop, MS; Mulrenin, IR; Urrutia, RP, 2021) |
| "To compare the efficacy of nifedipine and ritodrine in prolonging pregnancy beyond 48 h, 1 week and 36." | 5.12 | Nifedipine versus ritodrine for suppression of preterm labor. Comparison of their efficacy and secondary effects. ( Cararach, V; Cobo, T; Coll, O; Deulofeu, P; Martínez, S; Palacio, M; Sánchez, M, 2006) |
| "The aim of the present study was to determine whether the beneficial effect of oral supplementation with calcium and conjugated linoleic acid (CLA) in the reduction of the incidence of pregnancy-induced hypertension (PIH) is related with changes in plasma levels of prostanoids, renin, angiotensin II, calciotropic hormones, and plasma and intracellular ionized free calcium." | 5.12 | Calcium and conjugated linoleic acid reduces pregnancy-induced hypertension and decreases intracellular calcium in lymphocytes. ( Arévalo-Herrera, M; Ersheng, G; Garcia, RG; Herrera, JA; Herrera, S; López-Jaramillo, P; Shahabuddin, AK, 2006) |
| "The purpose of this study was to determine whether the slower- and longer-acting nifedipine tablets were as effective and safe as the rapid onset and short-acting nifedipine capsules for the treatment of acute severe hypertension in pregnancy." | 5.10 | Efficacy and safety of nifedipine tablets for the acute treatment of severe hypertension in pregnancy. ( Brown, MA; Buddle, ML; Davis, GK; Farrell, T, 2002) |
| "Magnesium sulfate may prevent eclampsia by reducing cerebral vasoconstriction and ischemia." | 5.10 | A comparison of magnesium sulfate and nimodipine for the prevention of eclampsia. ( Allen, JC; Anthony, J; Belfort, MA; Saade, GR, 2003) |
| "To study the effect of a calcium channel antagonist--Nifedipine(NIF) on the prevention and treatment of premature labor, the suppression of uterine contraction, the prolongation of pregnancy, and to observe the side effects of NIF." | 5.10 | [Clinical observations on the prevention and treatment of premature labor with nifedipine]. ( Liu, M; Zhang, X, 2002) |
| "Nifedipine is safe and more effective than hydralazine in controlling blood pressure in severe pre-eclampsia." | 5.10 | Nifedipine or hydralazine as a first-line agent to control hypertension in severe preeclampsia. ( Aali, BS; Nejad, SS, 2002) |
| "The objective of the present study is to compare the effectiveness of transdermal glyceryl-trinitrate versus oral nifedipine in lowering blood pressure in patients affected by pregnancy-induced hypertension (PIH)." | 5.09 | 24-hour ambulatory blood pressure monitoring: a comparison between transdermal glyceryl-trinitrate and oral nifedipine. ( Facchinetti, F; Menghini, S; Neri, I; Romanini, C; Valensise, H; Volpe, A, 1999) |
| "Maintenance therapy with oral nifedipine does not significantly prolong pregnancy in patients initially treated with intravenous magnesium sulfate for preterm labor." | 5.09 | Maintenance oral nifedipine for preterm labor: a randomized clinical trial. ( Carr, DB; Clark, AL; Kernek, K; Spinnato, JA, 1999) |
| "We sought to compare the efficacies of oral nifedipine and intravenous labetalol in the acute management of hypertensive emergencies of pregnancy." | 5.09 | A randomized, double-blind trial of oral nifedipine and intravenous labetalol in hypertensive emergencies of pregnancy. ( Chauhan, SP; Newman, RB; Scardo, JA; Vermillion, ST, 1999) |
| "Our purpose was to compare the hemodynamic effects of orally administered nifedipine and intravenously administered labetalol in preeclamptic hypertensive emergencies." | 5.09 | A randomized, double-blind, hemodynamic evaluation of nifedipine and labetalol in preeclamptic hypertensive emergencies. ( Chauhan, SP; Hogg, BB; Newman, RB; Scardo, JA; Vermillion, ST, 1999) |
| "To determine whether nifedipine or prazosin is the more appropriate second-line antihypertensive agent in pregnancy." | 5.09 | Nifedipine or prazosin as a second agent to control early severe hypertension in pregnancy: a randomised controlled trial. ( Hall, DR; Odendaal, HJ; Smith, M; Steyn, DW, 2000) |
| "The safety of use of the calcium channel blocker nifedipine in pregnancy as it affects child development has not been well evaluated." | 5.09 | Nifedipine administered in pregnancy: effect on the development of children at 18 months. ( Bortolus, R; Chatenoud, L; Parazzini, F; Ricci, E, 2000) |
| "To determine the efficacy of Nifedipine on postpartum blood Loss in patients with Pregnancy Induced Hypertension (PIH)." | 5.09 | [The effect of Nifedipine on postpartum blood loss in patients with pregnancy induced hypertension]. ( Liu, Y; Yang, X, 2000) |
| "To compare the effects of a single oral dose of nifedipine with those of intravenous dihydralazine on central haemodynamics in pregnant women with severe pre-eclampsia." | 5.08 | A comparison between the haemodynamic effects of oral nifedipine and intravenous dihydralazine in patients with severe pre-eclampsia. ( Visser, W; Wallenburg, HC, 1995) |
| "The purposes of this study were to compare the efficacy of sublingual nifedipine with intravenous hydrallazine in the control of acute hypertension of pregnancy and to make a preliminary assessment whether sublingual nifedipine could be recommended for use by midwives faced with severe hypertension in pregnancy in a rural setting." | 5.08 | Sublingual nifedipine compared with intravenous hydrallazine in the acute treatment of severe hypertension in pregnancy: potential for use in rural practice. ( Jegasothy, R; Paranthaman, S, 1996) |
| "To compare the effect of routine treatment with the calcium channel blocker nifedipine in mild to moderate hypertension in pregnancy." | 5.08 | Nifedipine versus expectant management in mild to moderate hypertension in pregnancy. Gruppo di Studio Ipertensione in Gravidanza. ( , 1998) |
| "To compare nifedipine (group 1) with methyldopa (group 2) in the management of pregnancy induced hypertension (PIH)." | 5.07 | A comparison of nifedipine with methyldopa in pregnancy induced hypertension. ( Jayawardana, J; Lekamge, N, 1994) |
| "In a prospective controlled trial 91 consecutive women with eclampsia were randomly allocated either to a magnesium sulphate and nifedipine regime or to a lytic cocktail and nifedipine group." | 5.07 | A safer and more effective treatment regimen for eclampsia. ( Bhalla, AK; Dhall, GI; Dhall, K, 1994) |
| "The therapeutic effect of the calcium antagonist; Nifedipine was assessed in 30 patients with pre-eclampsia." | 5.07 | Evaluation of calcium-antagonist (Nifedipine) in the treatment of pre-eclampsia. ( Ismail, AA; Kholeif, A; Medhat, I; Tawfic, TA, 1993) |
| "The objective was to compare the fetal and maternal effects between parenteral hydralazine and sublingual nifedipine used like antihypertensive drugs in the management of severe preeclampsia." | 5.07 | [Management of severe pre-eclampsia/eclampsia. Comparison between nifedipine and hydralazine as antihypertensive agents]. ( Flores Padilla, LM; Walss Rodriguez, RJ, 1993) |
| "Thirty women with pregnancy-induced hypertension (PIH) scheduled for Caesarean section under general anaesthesia were studied to evaluate the efficacy of sublingual nifedipine in attenuating the pressor response to laryngoscopy and tracheal intubation." | 5.07 | Nifedipine attenuates the hypertensive response to tracheal intubation in pregnancy-induced hypertension. ( Bala, I; Batra, YK; Gopalan, S; Kumar, N, 1993) |
| "The objective of our study was to test the hypothesis that treatment with nifedipine for mild preeclampsia remote from term reduces the number of days of maternal hospitalization and improves pregnancy outcome." | 5.07 | A randomized prospective comparison of nifedipine and bed rest versus bed rest alone in the management of preeclampsia remote from term. ( Akl, S; Barton, JR; Mercer, BM; Sarinoglu, C; Sibai, BM, 1992) |
| "The effect of nifedipine (Adalat; Bayer-Miles)--a calcium channel blocker, which has a well-established place in nonobstetric hypertension--was compared with dihydralazine in 33 primigravidas with severe hypertension of pregnancy." | 5.06 | Nifedipine in acute hypertensive emergencies in pregnancy. ( Becker, P; Moodley, J; Seabe, SJ, 1989) |
| "The effect of nifedipine on uteroplacental blood flow was investigated in nine hypertensive women in the trimester of pregnancy and compared with the effects of a placebo in nine similar hypertensive women." | 5.06 | The effect of sublingual nifedipine on uteroplacental blood flow in hypertensive pregnancy. ( Davey, DA; Davies, N; Lindow, SW; Smith, JA, 1988) |
| " The incidence of severe hypertension was significantly lower when nifedipine (odds ratio, 0." | 5.05 | Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis. ( Bellos, I; Daskalakis, G; Loutradis, D; Papapanagiotou, A; Pergialiotis, V, 2020) |
| "Hydralazine, labetalol, and nifedipine are the recommended first-line treatments for severe hypertension in pregnancy." | 5.01 | First-line antihypertensive treatment for severe hypertension in pregnancy: A systematic review and network meta-analysis. ( Alavifard, S; Chase, R; Chaumont, A; Gaudet, L; Janoudi, G; Lanes, A; Walker, M, 2019) |
| " There was no significant difference between atosiban and nifedipine for pregnancy prolongation of 48 hours or more regarding efficacy (RR 1." | 5.01 | Systematic review and meta-analysis of randomized controlled trials of atosiban versus nifedipine for inhibition of preterm labor. ( Abdel-Daim, MM; Ahmed, AMM; Ali, AA; Anwar, AT; El Sherif, L; Elgebaly, A; Loutfi, GO; Mohamed, HB; Sayed, AK; Taha, AS; Yahia, RM, 2019) |
| " Oral nifedipine is now considered an alternative first-line therapy, along with intravenous hydralazine and labetalol for women presenting with pre-eclampsia." | 4.98 | Focused Update on Pharmacologic Management of Hypertensive Emergencies. ( Broscious, R; Devabhakthuni, S; Noel, ZR; Watson, K, 2018) |
| "The present evidence suggests similar efficacy between nifedipine, hydralazine and labetalol in the treatment of severe hypertension in pregnancy." | 4.98 | Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials. ( Sequeira, RP; Sridharan, K, 2018) |
| "Oral nifedipine is recommended along with labetalol and hydralazine for treatment of severe hypertension during pregnancy by most authorities." | 4.93 | Oral nifedipine versus intravenous labetalol for severe hypertension during pregnancy: a systematic review and meta-analysis. ( Gupta, N; Kirubakaran, R; Pareek, P; Shekhar, S, 2016) |
| "To evaluate the effectiveness of maintenance tocolytic therapy with oral nifedipine on the reduction of adverse neonatal outcomes and the prolongation of pregnancy by performing an individual patient data meta-analysis (IPDMA)." | 4.93 | Nifedipine maintenance tocolysis and perinatal outcome: an individual participant data meta-analysis. ( Carr, DB; Clark, AL; Dijkema, GH; El-Sayed, YY; Heida, KY; Lyell, DJ; Mahdy, ZA; McCowan, L; Mol, BW; Oudijk, MA; Parry, EC; Roos, C; Sayin, NC; Schuit, E; Uma, M; van der Post, J; van Vliet, E; Varol, GF, 2016) |
| "Oral nifedipine, and possibly labetalol and methyldopa, are suitable options for treatment of severe hypertension in pregnancy/postpartum." | 4.90 | Oral antihypertensive therapy for severe hypertension in pregnancy and postpartum: a systematic review. ( Firoz, T; Gordon, R; MacDonell, K; Magee, LA; Payne, BA; Vidler, M; von Dadelszen, P, 2014) |
| "The objective of this review was to assess the effects of magnesium sulphate compared with phenytoin when used for the care of women with eclampsia." | 4.86 | Magnesium sulphate versus phenytoin for eclampsia. ( Chou, D; Duley, L; Henderson-Smart, DJ, 2010) |
| " No difference in the incidence of preterm birth was found when calcium channel blocker (nifedipine) maintenance therapy was compared with no treatment." | 4.82 | Maintenance therapy with calcium channel blockers for preventing preterm birth after threatened preterm labour. ( Crowther, CA; Gaunekar, NN, 2004) |
| "In this study, we presented 2 cases and evaluated the evidence for symptomatic hypocalcemia after treatment with magnesium sulfate alone or combined with use of nifedipine." | 4.82 | Symptomatic hypocalcemia after tocolytic therapy with magnesium sulfate and nifedipine. ( Friedman, SA; Koontz, SL; Schwartz, ML, 2004) |
| "Tradiational drug therapy choices for hypertension in pregnancy continue to be hydralazine for acute reduction of blood pressure and methyldopa for the management of chronic hypertension." | 4.79 | Use of nifedipine in the hypertensive diseases of pregnancy. ( Doering, PL; Hatton, RC; Levin, AC, 1994) |
| "The dihydropyridine group of calcium channel blockers (type II calcium blockers) and, specifically, nifedipine are safe for use in pregnancy." | 4.79 | Nifedipine and its indications in obstetrics and gynecology. ( Childress, CH; Katz, VL, 1994) |
| "We describe a case of colonic pseudo-obstruction occurring in a pregnant patient whose preterm labor was being treated with intravenous magnesium and nifedipine." | 4.79 | Acute pseudo-obstruction of the colon (Ogilvie's syndrome) resulting from combination tocolytic therapy. ( Danilewitz, MD; Pecha, RE, 1996) |
| "A retrospective cohort study of patients with severe peripartum hypertension (systolic blood pressure ≥ 160 mmHg and/or diastolic blood pressure ≥ 110 mm Hg confirmed within 15 min) to determine whether the effectiveness of blood pressure control using nationally recommended medications (hydralazine, labetalol, nifedipine) differed by race/ethnicity." | 4.12 | Race/ethnicity differences in response to acute antihypertensive treatment of peripartum severe hypertension. ( Greene, NH; Kilpatrick, SJ; Pon, FF, 2022) |
| "To assess whether readmission for hypertension by 6 weeks postpartum differed between patients discharged on nifedipine or labetalol." | 4.12 | Postpartum Readmission for Hypertension After Discharge on Labetalol or Nifedipine. ( Do, SC; Druzin, ML; El-Sayed, YY; Girsen, AI; Herrero, T; Kan, P; Leonard, SA; Lyell, DJ; Panelli, DM, 2022) |
| " The American College of Obstetricians and Gynecologists recommends that acute-onset, severe hypertension be treated with first line-therapy (intravenous labetalol, intravenous hydralazine or oral nifedipine) within 60 minutes to reduce risk of maternal morbidity and death." | 3.96 | Identification of factors associated with delayed treatment of obstetric hypertensive emergencies. ( Akerman, MB; Elsayad, A; Halpern, TA; Heiselman, CJ; Heo, HJ; Kantorowska, A; Muscat, JC; Sicuranza, GB; Vintzileos, AM, 2020) |
| "To compare the immediate-release (IR) and osmotic push-pull system formulations of nifedipine used for tocolysis in prolonging pregnancy, neonatal outcomes and maternal-fetal adverse effects." | 3.91 | Comparison of the efficacy of the immediate-release and osmotic push-pull system formulations of nifedipine for tocolysis. ( Dolgun, N; Erzincan, SG; Inan, C; Sayin, C; Sutcu, H; Uzun, I; Varol, F, 2019) |
| "The results suggest that exposure to nifedipine in human pregnancy 3-4 weeks postfertilization may cause a direct effect on the embryonic heart resulting in reduced blood flow leading to abnormal heart and/or blood vessel development and/or embryonic death." | 3.91 | The effects of nifedipine and ivabradine on the functionality of the early rat embryonic heart. Are these drugs a risk in early human pregnancy? ( Gustaffson, E; Ritchie, HE; Telenius, C; Webster, WS, 2019) |
| "Compelling evidence for the far-reaching role of oxytocin (OT) in social cognition and affiliative behaviors set the basis for examining the association between genetic variation in the OT receptor (OXTR) gene and risk for autism spectrum disorder (ASD)." | 3.91 | Cumulative Risk of the Oxytocin Receptor Gene Interacts with Prenatal Exposure to Oxytocin Receptor Antagonist to Predict Children's Social Communication Development. ( Feldstein, O; Friedlander, E; Harel-Gadassi, A; Israel, S; Laiba, E; Mankuta, D; Yaari, M; Yirmiya, N, 2019) |
| " We evaluated the ability of oxytocin receptor-targeted liposomes to localize to uterine tissue in vivo, and assessed if targeted liposomes loaded with indomethacin were capable of preventing lipopolysaccharide-induced preterm birth in mice." | 3.85 | Drug delivery to the human and mouse uterus using immunoliposomes targeted to the oxytocin receptor. ( Butler, T; Hua, S; Ilicic, M; Paul, JW; Robertson, S; Smith, R; Tolosa, JM, 2017) |
| "This study examines the differential role of calcium signaling pathway(s) in histamine-induced uterotonic action during early and mid-pregnancy stages in buffaloes." | 3.85 | Extra and intracellular calcium signaling pathway(s) differentially regulate histamine-induced myometrial contractions during early and mid-pregnancy stages in buffaloes (Bubalus bubalis). ( Choudhury, S; Garg, SK; Nakade, UP; Sharma, A; Yadav, RS, 2017) |
| "Present study unravels the involvement of different calcium signaling pathways in oxytocin-induced contractions in myometrium of non-pregnant and pregnant buffaloes during early and mid-pregnancy stages." | 3.85 | Functional involvement of protein kinase C, Rho-kinase and TRPC3 decreases while PLC increases with advancement of pregnancy in mediating oxytocin-induced myometrial contractions in water buffaloes (Bubalus bubalis). ( Choudhury, S; Garg, SK; Nakade, UP; Sharma, A, 2017) |
| "Doppler ultrasound and myography were utilised to assess uterine artery functional and structural changes pre-pregnancy and at gestational day 18 in SHRSP (untreated and nifedipine treated) and in the normotensive Wistar-Kyoto (WKY) rat." | 3.83 | Abnormal uterine artery remodelling in the stroke prone spontaneously hypertensive rat. ( Beattie, E; Delles, C; Graham, D; Griffin, S; Indahl, M; Morgan, H; Small, HY, 2016) |
| "Nifedipine is a dihydropyridine calcium channel blocker used for the treatment of hypertension in pregnant women." | 3.81 | Analysis of nifedipine in human plasma and amniotic fluid by liquid chromatography-tandem mass spectrometry and its application to clinical pharmacokinetics in hypertensive pregnant women. ( Carvalho, DM; Cavalli, RC; Duarte, G; Filgueira, GC; Filgueira, OA; Lanchote, VL; Marques, MP; Moisés, EC, 2015) |
| "To evaluate the risk of developing pulmonary edema in women exposed to nifedipine, magnesium sulfate (MgSO4), or both in a preterm setting." | 3.80 | Effect of magnesium sulfate and nifedipine on the risk of developing pulmonary edema in preterm births. ( Abenhaim, HA; Gangal, M; Xiao, C, 2014) |
| "To characterize the pharmacokinetics and pharmacogenetics of nifedipine in pregnancy." | 3.79 | Nifedipine pharmacokinetics are influenced by CYP3A5 genotype when used as a preterm labor tocolytic. ( Caritis, SN; Clark, S; Clay, JM; Haas, DM; Hebert, MF; Quinney, SK; Renbarger, JL; Umans, JG, 2013) |
| "Nine mothers were treated with labetalol and/or MgSO4 during pregnancy, three mothers with labetalol, MgSO4 and nifedipine, and 19 mothers with nifedipine only." | 3.79 | Maternal antihypertensive drugs may influence cerebral oxygen extraction in preterm infants during the first days after birth. ( Bos, AF; Kooi, EM; van den Berg, PP; Verhagen, EA, 2013) |
| "Investigation of methyldopa and nifedipine effects on maternal and fetal hemodynamics in women with mild gestational hypertension during the third pregnancy trimester." | 3.78 | Effects of methyldopa and nifedipine on uteroplacental and fetal hemodynamics in gestational hypertension. ( Folic, MD; Folic, MM; Jankovic, SM; Varjacic, MR, 2012) |
| "To analyse the expression of 15 genes encoding receptors and enzymes associated with the molecular mechanism of the tocolytic drugs atosiban (oxytocin receptor antagonist), nifedipine (calcium channel blocker) and celecoxib (selective cyclo-oxygenase-2 inhibitor) in preterm labor patients with premature rupture of fetal membranes in relation to symptoms of intrauterine infection and preterm labor risk factors." | 3.78 | Expression of selected genes in preterm premature rupture of fetal membranes. ( Chyczewski, L; Kowalczuk, O; Kuć, P; Laudański, P; Laudański, T, 2012) |
| "A retrospective study in hypertensive patients treated during pregnancy with nifedipine or labetalol was conducted." | 3.78 | Nifedipine versus labetalol in the treatment of hypertensive disorders of pregnancy. ( Battistoni, GI; Bezzeccheri, V; Cecchi, L; Cecchi, S; Giannubilo, SR; Landi, B; Tranquilli, AL; Vitali, P, 2012) |
| "Labetalol is commonly used for control of hypertension in pregnancy." | 3.77 | False-positive amphetamine toxicology screen results in three pregnant women using labetalol. ( Wu, D; Yee, LM, 2011) |
| "Alpha-methyldopa is a regularly used antihypertensive drug during pregnancy." | 3.76 | [Methyldopa-induced acute reactive hepatitis in pregnancy, drug-metabolizing capacity of the liver]. ( Monostory, K; Ozsvár, Z; Solymossi, Z, 2010) |
| "We investigated how progesterone and salmeterol modify the effect of nifedipine in an in vivo preterm birth model in rats, and how terbutaline and nifedipine modify the contractions of the isolated human myometrium." | 3.76 | Potentiation of the uterus-relaxing effects of β-adrenergic agonists with nifedipine: studies on rats and the human myometrium. ( Falkay, G; Gáspár, R; Hajagos-Tóth, J; Kormányos, Z; Pál, A, 2010) |
| " The aims of the study were to investigate the effects of nifedipine on potassium chloride (KCl)-evoked rat uterine contractions on the last day of pregnancy (22) in vitro, and the alterations in the effects of nifedipine on combination with BK(Ca-channel blockers paxillin and tetraethyl ammonium chloride in late pregnancy in vitro." | 3.76 | [Investigation of uterus-relaxing effects of nifedipine in the presence of terbutaline and K(+)-channel blockers]. ( Falkay, G; Gáspár, R; Hajagos-Tóth, J; Kormányos, Z; Pál, A, 2010) |
| "The aims of the study were to investigate the effects of nifedipine on potassium chloride (KCl)-evoked rat uterine contractions on different days of pregnancy in vitro, and the alterations in the effects of nifedipine on combination with terbutaline or progesterone." | 3.75 | Modification of the effect of nifedipine in the pregnant rat myometrium: the influence of progesterone and terbutaline. ( Falkay, G; Gáspár, R; Hajagos-Tóth, J, 2009) |
| " Pregnancy outcomes of women resuming nifedipine tocolysis ( N = 418) following hospitalization were compared with those having an alteration in treatment ( N = 238) to continuous subcutaneous terbutaline." | 3.74 | Management of recurrent preterm labor in twin gestations with nifedipine tocolysis. ( de la Torre, L; Desch, C; González-Quintero, VH; Istwan, NB; Rhea, DJ; Roca, L; Stanziano, GJ, 2008) |
| "We report the case of a 31-yr-old parturient at 34 weeks gestation of a twin pregnancy, who experienced acute pulmonary edema after tocolytic treatment with nifedipine, nicardipine and atosiban of > 48 hr in duration." | 3.74 | [Non-invasive ventilation for pulmonary edema associated with tocolytic agents during labour for a twin pregnancy]. ( Bazin, JE; Bolandard, F; Chanséaume, S; Constantin, JM; Gallot, D; Perbet, S; Vignaud, M; Zénut, M, 2008) |
| "The purpose of this study was to investigate the effects of K+ channel blockade on the uterorelaxant effects of nifedipine in human myometrium during pregnancy." | 3.74 | The relaxant effect of nifedipine in human uterine smooth muscle and the BK(Ca) channel. ( Morrison, JJ; Moynihan, AT; Smith, TJ, 2008) |
| "Women with breech presentation at term considered suitable for ECV were given nifedipine prior to the procedure." | 3.74 | Employing nifedipine as a tocolytic agent prior to external cephalic version. ( Edelstein, S; Nachum, Z; Salim, R; Shalev, E; Zafran, N, 2008) |
| "Study aim was assessment of clinical efficacy of mono therapy with nifedipine SR/GITS and combination of nifedipine SR/GITS and bisoprolol as well as investigation of functional state of sympathoadrenal system (SAS) in pregnant women with arterial hypertension." | 3.74 | [Clinical efficacy of antihypertensive therapy of pregnant women with arterial hypertension with long acting nifedipine and bisoprolol]. ( Brytkova, IaV; Bukhonkina, IuM; Pavlova, LN; Striuk, RI, 2008) |
| " She would like to know whether she can continue using metformin during the pregnancy and also is concerned about the effect of the gastric bypass surgery." | 3.74 | A 40-year-old woman with diabetes contemplating pregnancy after gastric bypass surgery. ( Coustan, DR, 2008) |
| "A meta-analysis of randomized controlled trials suggests that nifedipine appears to be a reasonable agent for treatment of acute severe hypertension in pregnancy." | 3.73 | Nifedipine for severe hypertension in pregnancy: emotion or evidence? ( Côté, AM; Magee, LA; von Dadelszen, P, 2005) |
| " We report the first case of acute pulmonary edema following tocolytic oral nifedipine." | 3.73 | Acute pulmonary edema during tocolytic therapy with nifedipine. ( Abbas, OM; Kanj, NA; Nassar, AH; Usta, IM, 2006) |
| "To assess the variation of body composition at term in patients with normal pregnancy and patients with gestational hypertension (GH) treated with nifedipine." | 3.72 | Nifedipine-induced changes in body composition in hypertensive patients at term. ( Altomare, F; Andreoli, A; Arduini, D; De Lorenzo, A; Larciprete, G; Novelli, G; Valensise, H; Vasapollo, B, 2003) |
| "These findings demonstrate that agents commonly used for the treatment of hypertensive disease in pregnancy, excluding alpha-methyldopa, have significant direct effects on the feto-placental circulation." | 3.72 | Anti-hypertensive therapy and the feto-placental circulation: effects on umbilical artery resistance. ( Dennedy, MC; Houlihan, DD; Morrison, JJ; Ravikumar, N, 2004) |
| "In 21 pregnancies complicated by pregnancy-induced hypertension (PIH) which was treated by antihypertensive drugs (labetalol, nifedipine), fetal behavioural recordings (quiet state, C1F; active state, C2F; no coincidence, NOC) and Doppler measurements of blood flow velocity in the umbilical artery (UA) (resistance index, RI) were made on two occasions (27-32 and 33-36 weeks of gestation)." | 3.70 | Pregnancy-induced hypertension, antihypertensive drugs and the development of fetal behavioural states. ( Bruschettini, PL; Gazzolo, D; Russo, A; Santi, F; Scopesi, F; Visser, GH, 1998) |
| "To describe the clinical course of pregnancies complicated by pulmonary hypertension and treated with the pulmonary vasodilators nifedipine and prostacyclin." | 3.70 | Pulmonary hypertension in pregnancy: treatment with pulmonary vasodilators. ( Easterling, TR; Ralph, DD; Schmucker, BC, 1999) |
| "The hypothesis that Ca2+ channel function is altered during pregnancy was tested by comparing responses to potassium chloride (KCl) and phenylephrine in aortic rings of virgin and term-pregnant rats under the influence of nifedipine and Bay K 8644." | 3.69 | Effects of nifedipine and Bay K 8644 on myotropic responses in aortic rings of pregnant rats. ( Brochu, M; Roy, B; Sicotte, B; St-Louis, J, 1995) |
| "Nifedipine has been used to treat hypertension in pregnancy, and does not influence fetal or uteroplacental circulations in patients with preeclampsia." | 3.69 | Changes in blood velocities of fetal circulation in association with fetal heart rate abnormalities: effect of sublingual administration of nifedipine. ( Hata, K; Hata, T; Kitao, M; Manabe, A, 1995) |
| " The uterus of adult progeny of rats treated with nifedipine during the late phase of pregnancy react in vitro to oxytocin less and the contractility of ones treated with higher dose (100 micrograms) disappears." | 3.69 | Effect of nifedipine treatment (imprinting) of rat feti and newborns on the responsiveness of adult rat's uterus. Extension of the imprinting theory. ( Csaba, G; Dobozy, O; Karabélyos, C; Kenéz, C, 1995) |
| "Nifedipine was administered to 49 pregnant women with gestational hypertension as first-line therapy, and were longitudinally studied as paired observations for 3 or 10 day intervals of treatment with nifedipine until delivery." | 3.69 | The use of nifedipine as first-line hypotensive therapy in gestational hypertension. ( Caruso, A; De Carolis, MP; De Carolis, S; Ferrazzani, S; Mancinelli, S; Romano, D, 1994) |
| "We assessed the action of nifedipine on vascular reactivity to angiotensin II (AII) in pregnant women at risk for hypertension." | 3.69 | Nifedipine reduces pressor responsiveness to angiotensin II in pregnant women. ( Conti, C; Garzetti, GG; Rezai, B; Romanini, C; Tranquilli, AL, 1994) |
| "A 34-year-old mother developed acute myocardial infarction (MI) 10 days postpartum while taking bromocriptine for ablactation." | 3.69 | Acute myocardial infarction in a healthy mother using bromocriptine for milk suppression. ( Hopp, L; Iffy, L; Weisse, AB, 1996) |
| " On the fifth day of tocolysis with magnesium sulfate, nifedipine, terbutaline and betamethasone, edema developed in both labia." | 3.69 | Massive vulvar edema complicating tocolysis in a patient with twins. A case report. ( Bennert, H; Stubblefield, PG; Trice, L, 1996) |
| "Our purpose was to evaluate the hemodynamic effects of oral nifedipine in preeclamptic hypertensive emergencies." | 3.69 | Hemodynamic effects of oral nifedipine in preeclamptic hypertensive emergencies. ( Hogg, BB; Newman, RB; Scardo, JA; Vermillion, ST, 1996) |
| "Our purpose was to determine whether the fetal acidosis and hypoxia previously demonstrated in animal models with maternal nifedipine infusion is the result of a decrease in uteroplacental or fetoplacental blood flow and whether this effect is exacerbated by a higher drug concentration and duration of infusion." | 3.69 | Effect of nifedipine on fetal and maternal hemodynamics and blood gases in the pregnant ewe. ( Barnard, JM; Blea, CW; Hendricks, SK; Magness, RR; Phernetton, TM, 1997) |
| "To investigate the effect of 7 to 14 days of therapy with nifedipine (sustained-release preparation) on the 24-hour blood pressure patterns of pregnant women with pre-eclampsia or chronic hypertension, and to test the utility of blood pressure monitoring in modulating the timing and dosage of the drug." | 3.69 | 24-hour blood pressure monitoring to evaluate the effects of nifedipine in pre-eclampsia and in chronic hypertension in pregnancy. ( Benedetto, C; Carandente, F; Chiarolini, L; Giarola, M; Maulà, V; Zonca, M, 1997) |
| "To study the effects of nifedipine on the microcirculation in pregnancy-induced hypertension (PIH)." | 3.69 | [The effect of nifedipine on the microcirculation in pregnancy-induced hypertension]. ( Hao, C; Li, F; Yu, X, 1996) |
| " Description of their management, usage of nifedipine, and pregnancy outcome." | 3.69 | Sublingual nifedipine in human pregnancy. ( Gallery, ED; Györy, AZ, 1997) |
| "To examine the efficacy of magnesium sulfate (MgSO4) as an anticonvulsant in eclampsia and imminent eclampsia." | 3.69 | Magnesium sulfate as an anticonvulsant in eclampsia. ( Raman, NV; Rao, CA, 1995) |
| " (2) In rat and human myometrium an L-arginine-nitric oxide system has an important role in inhibiting uterine contractility and possibly maintaining pregnancy." | 3.68 | Gestational changes in L-arginine-induced relaxation of pregnant rat and human myometrial smooth muscle. ( Garfield, RE; Izumi, H; Yallampalli, C, 1993) |
| "The effects of cadmium (Cd) exposure during the preimplantation period of pregnancy on the subsequent development and implantation of mouse embryos were examined." | 3.68 | Stage-specific effects of cadmium on preimplantation embryo development and implantation in the mouse. ( Andrews, GK; De, SK; Dey, SK; Paria, BC, 1993) |
| "Although the calcium antagonist nifedipine has been reported to suppress preterm labor, little is known of the effects of long-term nifedipine use in late pregnancy." | 3.68 | The effects of nifedipine on pregnancy outcome and morphology of the placenta, uterus, and cervix during late pregnancy in the rat. ( Richichi, J; Vasilenko, P, 1992) |
| "The pharmacokinetics of oral nifedipine were studied in 15 women with pregnancy-induced hypertension in the third trimester of pregnancy to determine if the drug's disposition was different from that in nonpregnant patients." | 3.68 | Oral nifedipine pharmacokinetics in pregnancy-induced hypertension. ( Akl, SA; Prevost, RR; Sibai, BM; Whybrew, WD, 1992) |
| "The short-term effect of 20 mg of oral nifedipine on maternal and fetal hemodynamics was investigated in 12 women with pregnancy-induced hypertension." | 3.68 | Uterine and fetal flow velocity waveforms in hypertensive pregnancy: the effect of a single dose of nifedipine. ( Ekblad, UU; Erkkola, RU; Pirhonen, JP, 1990) |
| "The case is reported of successful conception and pregnancy in a woman with systemic sclerosis while receiving continuous treatment with nifedipine 30 mg/day, after a previously poor obstetric record and involuntary secondary infertility." | 3.68 | Successful pregnancy in a woman with systemic sclerosis while taking nifedipine. ( Kirby, JD; Wilson, AG, 1990) |
| "In a recent study, the vasodilating drugs nifedipine, nitrendipine, felodipine, and hydralazine induced phalangeal defects in rabbits, when given on day 16 of pregnancy." | 3.68 | Histological and in vitro studies supporting decreased uteroplacental blood flow as explanation for digital defects after administration of vasodilators. ( Danielson, M; Danielsson, BR; Dencker, L; Regård, CG; Reiland, S; Rundqvist, E, 1990) |
| "The effect of lowering the maternal blood pressure with sublingual nifedipine on the fetal heart rate was studied in 51 patients with severe pregnancy-induced hypertension." | 3.68 | Effect of nifedipine on fetal heart rate in the treatment of severe pregnancy-induced hypertension. ( Fenakel, K; Friedman, A; Lurie, S, 1990) |
| "The calcium antagonist, nifedipine, was given orally to 21 women with acute episodes of severe hypertension during pregnancy or in the puerperium." | 3.67 | Treatment of severe pregnancy-associated hypertension with the calcium antagonist nifedipine. ( Redman, CW; Walters, BN, 1984) |
| " The influence of ovarian steroids produced during pregnancy (oestrogen and progesterone) on the potency and maximum effect of two calcium entry blockers (nifedipine and diltiazem) against uterine contractions during i." | 3.67 | The influence of oestrogen and progesterone on the actions of two calcium entry blockers in the rat uterus. ( Downing, SJ; Hollingsworth, M; Miller, M, 1988) |
| "Hyperphalangeal bones were found in postnatal rat pups of mothers treated with nifedipine during pregnancy." | 3.67 | Hyperphalangeal bones induced in rat pups by maternal treatment with nifedipine. ( Hasegawa, Y; Kanamori, S; Yoshida, T, 1988) |
| "Slow-release nifedipine has been used in the treatment of severe hypertension in 23 pregnant women." | 3.67 | Nifedipine as a second line antihypertensive drug in pregnancy. ( Beevers, DG; Constantine, G; Luesley, DM; Reynolds, AL, 1987) |
| "The effects of the calcium antagonist, nifedipine, on uterine activity induced by prostaglandins F2 alpha (PGF2 alpha) and E2 (PGE2) were studied in women undergoing therapeutic midtrimester abortion, and in patients with a missed abortion in the 16th to 27th week of pregnancy." | 3.66 | Inhibition of prostaglandin-induced uterine activity by nifedipine. ( Andersson, KE; Ingemarsson, I; Ulmsten, U; Wingerup, L, 1979) |
| "Preeclampsia is associated with maternal and perinatal morbidity." | 3.30 | Trial of Intrapartum Extended-Release Nifedipine to Prevent Severe Hypertension Among Pregnant Individuals With Preeclampsia With Severe Features. ( Cleary, EM; Costantine, MM; Kudrimoti, M; Patton, KG; Racchi, NW; Rood, KM, 2023) |
| "Hypertension during pregnancy is associated with a higher risk of cardiovascular disease and kidney failure." | 3.01 | Evaluation and Management of Hypertensive Disorders of Pregnancy. ( Bajpai, D; Dumanski, S; Popa, C; Shah, S; Verma, P, 2023) |
| "Preterm birth is the most common cause of neonatal morbidity and mortality." | 3.01 | The effectiveness of nifedipine/indomethacin combination therapy and nifedipine monotherapy for postponing preterm birth (25-34 weeks of gestation) in Sudanese women: a randomized clinical trial study protocol. ( Abdelrahiem, SK; Adam, I; Elfaki, T; Elhassan, EM; Ibrahim, MH, 2021) |
| "To study the tocolytic action of nifedipine combined with sildenafil citrate (SC) and if the combination is superior to nifedipine alone in inhibiting threatened preterm labour (PTL)." | 2.90 | Nifedipine alone or combined with sildenafil citrate for management of threatened preterm labour: a randomised trial. ( El-Khadry, SW; Maher, MA; Sayyed, TM, 2019) |
| " Hence, the data suggest gastroretention as a promising approach to enhance bioavailability of nifedipine." | 2.90 | Formulation, Optimization, and In vivo Evaluation of Gastroretentive Drug Delivery System of Nifedipine for the Treatment of Preeclampsia. ( Avari, JG; Karemore, MN, 2019) |
| "A total of 626 patients with preeclampsia were enrolled, screened, and assigned by random to groups receiving either nifedipine + placebo or nifedipine + celastrol orally." | 2.84 | Celastrol synergizes with oral nifedipine to attenuate hypertension in preeclampsia: a randomized, placebo-controlled, and double blinded trial. ( Liang, Y; Wang, D; Xiao, S; Zhang, M, 2017) |
| "Nifedipine was found to be more effective than other antihypertensive medications to reduce blood pressure, particularly in patients with severe hypertension." | 2.82 | Comparative efficacy and safety of oral nifedipine with other antihypertensive medications in the management of hypertensive disorders of pregnancy: a systematic review and meta-analysis of randomized controlled trials. ( Adela, R; George, R; Joy, CA; Thomas, C; Undela, K; Varghese, B, 2022) |
| " In women in preterm labour, we compared the impact of terbutaline versus nifedipine on inhibition of uterine contractions, preterm birth, neonatal sepsis, intracranial haemorrhage or necrotizing enterocolitis, death or admission to a neonatal intensive care unit and maternal adverse reactions." | 2.80 | Nifedipine versus terbutaline, tocolytic effectiveness and maternal and neonatal adverse effects: a randomized, controlled pilot trial. ( Guyatt, G; Lopes, LC; Padovani, TR, 2015) |
| "Women with symptoms of preterm labor between 24 and 34 weeks, intact membranes, cervical length between 10 and 30 mm, and negative fibronectin test were randomly allocated to nifedipine (80 mg/day) or placebo." | 2.80 | Randomized comparison of nifedipine and placebo in fibronectin-negative women with symptoms of preterm labor and a short cervix (APOSTEL-I Trial). ( Bax, CJ; Bloemenkamp, KW; Bolte, AC; Bossuyt, PM; Cornette, J; Duvekot, JJ; Franssen, MT; Kwee, A; Mol, BW; Nij Bijvank, SW; Opmeer, BC; Oudijk, MA; Porath, MM; Scheepers, HC; Sollie, KM; Spaanderman, ME; van Baaren, GJ; van der Post, JA; van Eyck, J; van Lith, JM; Vandenbussche, FP; Vis, JY; Wilms, FF; Woiski, M, 2015) |
| "Management of preterm labor and prevention from preterm delivery in order to lower these risks have always been under serious concern." | 2.79 | Comparison between nitroglycerin dermal patch and nifedipine for treatment of preterm labor: a randomized clinical trial. ( Kashanian, M; Sheikhansari, N; Zamen, Z, 2014) |
| "In threatened preterm labor, maintenance tocolysis with nifedipine, after an initial course of tocolysis and corticosteroids for 48 hours, may improve perinatal outcome." | 2.78 | Effect of maintenance tocolysis with nifedipine in threatened preterm labor on perinatal outcomes: a randomized controlled trial. ( Bloemenkamp, KW; Bolte, AC; Cornette, J; de Groot, CJ; Duvekot, JJ; Franssen, MT; Kok, JH; Kwee, A; Lotgering, FK; Merién, A; Mol, BW; Nij Bijvank, B; Opmeer, BC; Oudijk, MA; Papatsonis, DN; Porath, MM; Roos, C; Scheepers, HC; Scherjon, SA; Schuit, E; Sollie, KM; Spaanderman, ME; van der Post, JA; van Eyck, J; van Pampus, MG; Vijgen, SM; Willekes, C, 2013) |
| " Non-compartmental pharmacokinetic analysis was used to estimate nifedipine exposure at steady state." | 2.77 | A pilot study of the impact of genotype on nifedipine pharmacokinetics when used as a tocolytic. ( Haas, DM; Jones, DR; McCormick, CL; Quinney, SK; Renbarger, JL, 2012) |
| "Women diagnosed with threatened preterm labor between 22 and 35 weeks' gestation scheduled to receive nifedipine tocolysis and prophylactic antenatal corticosteroid were randomized to a single intramuscular injection of 250 mg of 17-OHPC or placebo saline in a double-blind fashion." | 2.77 | Single dose 17 alpha-hydroxyprogesterone caproate in preterm labor: a randomized trial. ( King, AS; Omar, SZ; Tan, PC; Vallikkannu, N, 2012) |
| "Complications in early-onset mild gestational hypertension (GH) are better predicted by total peripheral vascular resistance (TPVR) > 1350 dyne than by blood pressure." | 2.77 | Medical treatment of early-onset mild gestational hypertension reduces total peripheral vascular resistance and influences maternal and fetal complications. ( Gagliardi, G; Giannini, L; Manfellotto, D; Novelli, GP; Pisani, I; Tiralongo, GM; Valensise, H; Vasapollo, B, 2012) |
| "Women in acute preterm labor with cervical dilatation 1-6 cm were randomized to receive one of three first-line tocolytic drugs." | 2.77 | Effect of antenatal tocolysis on neonatal outcomes. ( Briery, CM; Keiser, SD; Klauser, CK; Kosek, MA; Martin, RW; Morrison, JC, 2012) |
| "Nifedipine was appropriate for contraction inhibition when the cervical length was less than 30 mm with statistical significance." | 2.77 | Effect of cervical length to the efficacy of nifedipine and bed rest for inhibiting threatened preterm labor. ( Chawanpaiboon, S; Sutantawibul, A, 2012) |
| "Atosiban has fewer failures within 48 hours." | 2.77 | Nifedipine compared with atosiban for treating preterm labor: a randomized controlled trial. ( Baram, S; Garmi, G; Nachum, Z; Salim, R; Shalev, E; Zafran, N, 2012) |
| "Indomethacin was less effective than nifedipine for the fast treatment of preterm labor." | 2.76 | Comparison of the efficacy and adverse effects of nifedipine and indomethacin for the treatment of preterm labor. ( Bahasadri, S; Kashanian, M; Zolali, B, 2011) |
| "At present, women with threatened preterm labor before 32 weeks of gestation are, after transfer to a perinatal center, treated with tocolytics and corticosteroids." | 2.74 | Cost-effectiveness of fibronectin testing in a triage in women with threatened preterm labor: alleviation of pregnancy outcome by suspending tocolysis in early labor (APOSTEL-I trial). ( Bloemenkamp, KW; Bolte, AC; Cornette, J; Derks, JB; Duvekot, JJ; Kwee, A; Lotgering, FK; Mol, BW; Opmeer, BC; Oudijk, MA; Porath, MM; Scheepers, HC; Scherjon, SA; Sollie, KM; Spaanderman, ME; van der Post, JA; van Eyck, J; van Pampus, MG; Vis, JY; Willekes, C; Wilms, FF, 2009) |
| "Nifedipine was associated with fewer maternal adverse effects." | 2.73 | Magnesium sulfate compared with nifedipine for acute tocolysis of preterm labor: a randomized controlled trial. ( Burrs, D; Campbell, L; Caughey, AB; Ching, S; Chitkara, U; Druzin, ML; El-Sayed, YY; Lyell, DJ; Pullen, K, 2007) |
| "Terbutaline was initially infused with the rate 10 g/min with an increment 5 microg/min every 10 minutes if required, until 25 microg/min was reached." | 2.73 | Safety and efficacy of oral nifedipine versus terbutaline injection in preterm labor. ( Laohapojanart, N; Ratanajamit, C; Soorapan, S; Wacharaprechanont, T, 2007) |
| "GITS tablets 90 mg/d are an alternative dosage regimen to previous used slow-release tablets 60 mg/d for tocolysis with similar pharmacokinetic profile and a good tolerance." | 2.73 | Nifedipine gastrointestinal therapeutic system (GITS) as an alternative to slow-release for tocolysis--tolerance and pharmacokinetic profile. ( Burkhardt, T; Juon, AM; Krähenmann, F; Kühn-Velten, WN; von Mandach, U; Zimmermann, R, 2008) |
| "Nifedipine is a calcium channel blocker in widespread clinical use for preterm labour due to its ability to inhibit uterine contractions in that setting." | 2.72 | Nifedipine for primary dysmenorrhoea. ( Earl, RA; Grivell, RM, 2021) |
| "Use of nifedipine for preterm labor is associated with a lower incidence of adverse hemodynamic and metabolic changes compared with ritodrine after 24 and 48 h of tocolysis." | 2.71 | Hemodynamic and metabolic effects after nifedipine and ritodrine tocolysis. ( Adèr, HJ; Bleker, OP; Dekker, GA; Papatsonis, DN; van Geijn, HP, 2003) |
| "The study included 73 patients with preterm labor with intact membranes." | 2.71 | Oral nifedipine maintenance therapy after acute intravenous tocolysis in preterm labor. ( Balkanli-Kaplan, P; Sayin, M; Sayin, NC; Varol, FG, 2004) |
| "Atosiban is an effective and safe drug for the acute treatment of preterm labor with minimal side effects, and it can be an option in the treatment of preterm labor, especially in patients with heart disease and multi-fetal pregnancies." | 2.71 | Atosiban and nifedipin for the treatment of preterm labor. ( Akbarian, AR; Kashanian, M; Soltanzadeh, M, 2005) |
| "Nifedipine is a valid and well-tolerated alternative among the tocolytic drugs, and apparently does not significantly alter fetal vascular blood flow." | 2.69 | A prospective, randomized trial of nifedipine vs. ritodrine in threatened preterm labor. ( García-Velasco, JA; González González, A, 1998) |
| "Nifedipine for treatment of preterm labor was associated with a lower incidence of neonatal morbidity than ritodrine." | 2.69 | Neonatal effects of nifedipine and ritodrine for preterm labor. ( Adèr, HJ; Bleker, OP; Dekker, GA; Kok, JH; Papatsonis, DN; van Geijn, HP, 2000) |
| "In nifedipine-treated non-pregnant controls, only EC80 for adrenaline-induced aggregation decreased." | 2.68 | Nifedipine reduces thromboxane A2 production by platelets without changing aggregation in hypertensive pregnancy. ( Manninen, A, 1996) |
| "One hundred forty-eight women with mild preeclampsia were randomly allocated to treatment with either bed rest alone (n=64) or in combination with nifedipine (n=84) at 26-36 weeks' gestation." | 2.68 | The effect of nifedipine on urinary excretion of calcium in preeclampsia. ( Barton, JR; Mercer, BM; Sibai, BM, 1997) |
| "The patients with preeclampsia undergoing emergent cesarean section is always a challenge to an anesthesiologist, because severe hypertensive response after laryngoscopy and tracheal intubation may result in life-threatening complication such as cerebral hemorrhage." | 2.67 | [Nifedipine in preeclampsia for cesarean section]. ( Chen, JC; Hong, YJ; Lin, CF; Pan, P; Wei, TT; Wong, KL, 1993) |
| "Nifedipine was as effective as terbutaline in preventing recurrent labor, 26% versus 24%, and in achieving a gestation > 34 weeks, 62% versus 68%." | 2.67 | Efficacy and safety of nifedipine versus magnesium sulfate in the management of preterm labor: a randomized study. ( Glock, JL; Morales, WJ, 1993) |
| "Treatment of preterm labor with beta-sympathomimetics has been questioned because of the many maternal and fetal complications associated with its use." | 2.67 | Comparison of nifedipine and ritodrine for the treatment of preterm labor. ( Bracero, LA; Kirshenbaum, N; Leikin, E; Tejani, N, 1991) |
| "Nifedipine is a calcium channel blocker that reduces blood pressure and increases renal blood flow." | 2.67 | The use of nifedipine during the postpartum period in patients with severe preeclampsia. ( Barton, JR; Conover, WB; Hiett, AK, 1990) |
| "Fifty-eight women in preterm labor were selected randomly to receive either oral nifedipine or intravenous ritodrine hydrochloride." | 2.67 | Nifedipine versus ritodrine for suppressing preterm labor. ( Graves, WL; Meyer, WR; Randall, HW, 1990) |
| "Normal pregnancy is a complex and dynamic process that requires significant adaptation from the maternal system." | 2.66 | Hemodynamic Complications in Pregnancy: Preeclampsia and Beyond. ( Doherty, A; Kingdom, JC; McLaughlin, K, 2020) |
| "Nifedipine was found to be significantly more effective than ritodrine or withholding therapy, and was almost devoid of side-effects." | 2.66 | The use of a calcium antagonist (nifedipine) to suppress preterm labour. ( Read, MD; Wellby, DE, 1986) |
| "Pregnancy-induced hypertension is a major cause of maternal and fetal morbidity and mortality." | 2.61 | Hypertension and Pregnancy: Management and Future Risks. ( Jim, B; Reddy, S, 2019) |
| "Following a systematic review of the literature, we have provided an overview of the use of tocolytics for the prevention of preterm birth and have examined the fetal and maternal adverse effects of the various tocolytic agents currently in use." | 2.53 | The safety of tocolytics used for the inhibition of preterm labour. ( Jørgensen, JS; Lamont, CD; Lamont, RF, 2016) |
| "When preterm labor is actually threatening, current pharmacological therapies focus on inhibition of preterm contractions." | 2.50 | Preterm labor: current pharmacotherapy options for tocolysis. ( Boormans, EM; de Lange, TS; Mol, BW; Oudijk, MA; van Vliet, EO, 2014) |
| " Another important focus for future trials is identifying optimal dosage regimens of different types of CCBs (high versus low, particularly addressing speed of onset of uterine quiescence) and formulation (capsules versus tablets)." | 2.50 | Calcium channel blockers for inhibiting preterm labour and birth. ( Carbonne, B; Flenady, V; Jardine, LA; Murray, L; Papatsonis, DN; Stock, OM; Wojcieszek, AM, 2014) |
| "The pathophysiology leading to preterm labor is not well understood and often multifactorial; initiating factors include intrauterine infection, inflammation, ischemia, overdistension, and hemorrhage." | 2.48 | Tocolytic therapy for acute preterm labor. ( Abramovici, A; Cantu, J; Jenkins, SM, 2012) |
| "Nifedipine was associated with a significant reduction in the risk of delivery within 7 days of initiation of treatment and before 34 weeks' gestation, respiratory distress syndrome, necrotizing enterocolitis, intraventricular hemorrhage, neonatal jaundice, and admission to the neonatal intensive care unit when compared with β₂-adrenergic-receptor agonists." | 2.47 | Nifedipine in the management of preterm labor: a systematic review and metaanalysis. ( Conde-Agudelo, A; Kusanovic, JP; Romero, R, 2011) |
| "Risk factors for the development of preeclampsia include microvascular diseases, such as diabetes mellitus; vascular and connective tissue disorders; hypertension; antiphospholipid antibody syndrome; and nephropathy." | 2.45 | Pharmacotherapeutic options for the treatment of preeclampsia. ( Baldwin, K; McCoy, S, 2009) |
| "Atosiban is a new advance in the management of spontaneous preterm labor." | 2.44 | The choice of a tocolytic for the treatment of preterm labor: a critical evaluation of nifedipine versus atosiban. ( Lamont, RF; Lyndrup, J, 2007) |
| "Preterm birth is the major cause of perinatal mortality and morbidity in the developed world." | 2.44 | Developments in the pharmacotherapeutic management of spontaneous preterm labor. ( Kam, KY; Lamont, RF, 2008) |
| " Several relatively small randomised trials have compared calcium channel blockers with beta-agonists and the meta-analyses of these studies have demonstrated superior or comparable efficacy and a superior adverse events profile." | 2.43 | Calcium channel blockers for tocolysis: a review of their role and safety following reports of serious adverse events. ( Oei, SG, 2006) |
| "Hypertension that complicates preeclampsia in pregnancy is a disorder that requires special consideration in both prevention and pharmacologic treatment." | 2.43 | Pathophysiology and medical management of systemic hypertension in preeclampsia. ( Frishman, WH; Schlocker, SJ; Tejani, N; Veresh, M, 2006) |
| "Nifedipine tocolysis was associated with a significant reduction in respiratory distress syndrome compared with atosiban (OR 0." | 2.42 | Effectiveness of nifedipine versus atosiban for tocolysis in preterm labour: a meta-analysis with an indirect comparison of randomised trials. ( Coomarasamy, A; Gee, H; Khan, KS; Knox, EM; Song, F, 2003) |
| " These modifications are generally responsible for reduced plasma concentration and reduced half-life of most drugs." | 2.42 | Pharmacokinetics of tocolytic agents. ( Cabrol, D; Carbonne, B; Tsatsaris, V, 2004) |
| "Nifedipine also has the benefit of oral administration, in contrast with beta 2-sympathicomimetics which are administered intravenously." | 2.41 | [Nifedipine first choice in management of threatening preterm labor]. ( Oei, SG; Papatsonis, DN; Timmerman, CC; van Geijn, HP, 2002) |
| "While nitroprusside is commonly used to treat severe hypertension, it is an extremely toxic drug that should only be used in rare circumstances." | 2.41 | The diagnosis and management of hypertensive crises. ( Marik, PE; Varon, J, 2000) |
| "Treatment with nifedipine was interrupted significantly less often because of side effects (OR 0." | 2.41 | Tocolysis with nifedipine or beta-adrenergic agonists: a meta-analysis. ( Carbonne, B; Dekker, G; Goffinet, F; Papatsonis, D; Tsatsaris, V, 2001) |
| "Nifedipine is an effective and safe drug to use when tocolytic therapy is indicated for preterm labor." | 2.41 | Calcium channel blockers in the management of preterm labor and hypertension in pregnancy. ( Bos, JM; Dekker, GA; Geijn, HP; Lok, CA; Papatsonis, DN, 2001) |
| "Exploration of possible genetic predisposition is just beginning." | 2.41 | Preterm labour. ( Bennett, PR; Terzidou, V, 2002) |
| "We still do not have an ideal drug to treat acute severe hypertension in pregnancy." | 2.40 | Management of acute severe hypertension and encephalopathy. ( Mabie, WC, 1999) |
| "Nifedipine has both vasodilator and relaxant actions in arterial smooth muscle and other tissues, like uterus." | 2.38 | [Nifedipine in gynecology and obstetrics]. ( Palma-Aguirre, JA; Rodríguez-Palomares, C, 1992) |
| "A review of the pathophysiology and treatment of pre-eclampsia indicates that vasospasm and vascular hyperreactivity are important elements in the disease process and its control." | 2.36 | Possible treatment of pre-eclampsia with calcium channel blocking agents. ( Zaret, GM, 1983) |
| "Nifedipine treatment did not reduce gene expression or protein secretion of pro-inflammatory cytokines in either cultured myometrial cells or ex vivo tissues." | 1.91 | Assessment of the tocolytic nifedipine in preclinical primary models of preterm birth. ( Arman, BM; Beard, S; Binder, NK; de Alwis, N; Debruin, DA; Hannan, NJ; Hayes, A; Kaitu'u-Lino, TJ; Tong, S, 2023) |
| " Therapy success: systolic blood pressure ~140 mm Hg and diastolic blood pressure ~90 mm Hg, therapy failure: persistent systolic blood pressure ≥ 160 or diastolic blood pressure ≥ 110 mm Hg after maximum dosage of therapy (EL)." | 1.91 | Comparison of outcomes following intravenous magnesium compared with intravenous labetalol and oral nifedipine in 355 pregnant Han Chinese women with preeclampsia. ( Dong, W; Peng, Z; Xiao, Y; Zhang, J, 2023) |
| "Nifedipine treatment seems not to affect systolic or diastolic functions." | 1.72 | Fetal echocardiographic evaluation before and after nifedipine treatment in preterm labor. ( Goncu Ayhan, S; Menekse Beser, D; Oluklu, D; Sahin, D; Tugrul Ersak, D; Uyan Hendem, D; Yildirim, M, 2022) |
| "The HDP spectrum includes gestational hypertension (HTN), preeclampsia, eclampsia, HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome, chronic HTN, and chronic HTN with superimposed preeclampsia." | 1.72 | Hypertensive Conditions: Hypertensive Disorders in Pregnancy. ( Daly, PL; Goodwin, ET; Kipnis, CM; Smith, DK, 2022) |
| "In fetal hypoxemia, sildenafil had detrimental effects on placental hemodynamics that disturbed placental gas exchange." | 1.56 | Effects of nifedipine and sildenafil on placental hemodynamics and gas exchange during fetal hypoxemia in a chronic sheep model. ( Acharya, G; Alanne, L; Bhide, A; Haapsamo, M; Hoffren, J; Huhta, H; Kokki, M; Lantto, J; Räsänen, J, 2020) |
| "To explore the regulatory effect of magnesium sulfate combined with nifedipine and labetalol on disease-related molecules in serum and placenta in the treatment of preeclampsia." | 1.56 | Regulation of magnesium sulfate combined with nifedipine and labetalol on disease-related molecules in serum and placenta in the treatment of preeclampsia. ( Wang, DJ; Wu, Y; Zhang, R; Zhang, Y; Zhang, YX, 2020) |
| "Physiologically based pharmacokinetic modeling is considered a valuable tool for predicting pharmacokinetic changes in pregnancy to subsequently guide in-vivo pharmacokinetic trials in pregnant women." | 1.48 | A Physiologically Based Pharmacokinetic Model for Pregnant Women to Predict the Pharmacokinetics of Drugs Metabolized Via Several Enzymatic Pathways. ( Coboeken, K; Dallmann, A; Eissing, T; Hempel, G; Ince, I, 2018) |
| "Cortical dysplasia is the most common etiology of intractable epilepsy." | 1.48 | Axon Initial Segment Structural Plasticity is Involved in Seizure Susceptibility in a Rat Model of Cortical Dysplasia. ( Feng, L; Wang, YL; Xiao, B; Yue, ZW, 2018) |
| "Pregnancy is a physiological alteration that can affect urinary bladder." | 1.48 | Effect of pregnancy on cooling tone and rhythmic contractions of the rat urinary bladder. ( Mustafa, S, 2018) |
| "IgA nephropathy is one of the most common causes of renal hypertension." | 1.48 | Pregnancy-induced complications in IgA nephropathy: A case report. ( Chen, H; Fan, L; Li, X; Tian, G; Wu, Y, 2018) |
| "Tamsulosin or nifedipine were added at cumulative concentrations (0." | 1.48 | Impact of tamsulosin and nifedipine on contractility of pregnant rat ureters in vitro ( Blouin, S; Corriveau, S; Haddad, L; Pasquier, JC; Ponsot, Y; Rousseau, E; Roy-Lacroix, MÈ, 2018) |
| "Preeclampsia is characterised by systemic endothelial cell dysfunction thought to be triggered by toxic/dangerous factors from the placenta, including placental extracellular vesicles (EVs)." | 1.46 | Treating normal early gestation placentae with preeclamptic sera produces extracellular micro and nano vesicles that activate endothelial cells. ( Chamley, LW; Chen, Q; Stone, PR; Tong, M; Wise, MR; Xiao, F; Xiao, X; Zhao, M, 2017) |
| "In 14 patients with preeclampsia, 55 hypertensive emergencies were identified (BP >150/95)." | 1.46 | A trial of oral nifedipine and oral labetalol in preeclampsia hypertensive emergency treatment. ( Arjona-Berral, JE; Castelo-Branco, C; Duro-Gómez, J; Duro-Gómez, L; Giménez de Azcárete, M; Hernández-Angeles, C; Rodríguez-Marín, AB, 2017) |
| "Nifedipine tocolysis was associated with hemodynamic changes in non-hypertensive women." | 1.42 | Hemodynamic effects of nifedipine tocolysis. ( Burlingame, J; Kaneshiro, B; Yamasato, K, 2015) |
| "Nifedipine may cause cardiorespiratory adverse effects warranting a close monitoring." | 1.42 | [Adverse effects and hemodynamic effects of nifedipine as a tocolytic]. ( Audibert, F; Bussières, JF; Carceller, AM; Ferreira, E; Lachance, C; Martin, B; Spiesser-Robelet, L; Touzin, K, 2015) |
| "Oral nifedipine is a safe tocolytic agent with no long-term effect on fetomaternal circulation in pregnant women at risk of preterm delivery." | 1.42 | The effect of nifedipine tocolysis on Doppler indices of the uterine and umbilical arteries. ( Kaya, C; Özmen Bayar, Ü; Ulubaşoğlu, H; Ungan, B, 2015) |
| "Women with preeclampsia have elevated levels of inflammatory cytokines including IL-6." | 1.42 | The reduction of circulating levels of IL-6 in pregnant women with preeclampsia by magnesium sulphate and nifedipine: In vitro evidence for potential mechanisms. ( Chamley, LW; Chen, Q; Guo, F; Stone, PR; Xiao, JP; Yin, YX; Zhao, M, 2015) |
| "Totally 704 preeclampsia patients were randomly assigned to the treatment group and the control group, 352 cases in each group." | 1.42 | [Effect of Magnesium Sulfate, Nifedipine Tablet Combined Salvia Injection on ET-1/NO, TXA2/PGI2 and Hemorheology of Preeclampsia Patients]. ( Li, M; Qiu, SQ; Yao, J; Zhang, M; Zheng, XY; Zhu, JM; Zhu, ZX, 2015) |
| "Pre-treatment with nifedipine (10(-8) M), tetraethylammonium (10(-3) M), and theophylline (10(-5) M) attenuated the contracting effect of d- and l-limonene, while in the presence of paxilline (10(-5) M) d- and l-limonene were ineffective." | 1.42 | Effects of d- and l-limonene on the pregnant rat myometrium in vitro. ( Gáspár, R; Hajagos-Tóth, J; Hódi, Á; Seres, AB, 2015) |
| "Mean ± SD ZFP was lower in women with preeclampsia than in controls (16." | 1.40 | Cerebral perfusion pressure in women with preeclampsia is elevated even after treatment of elevated blood pressure. ( Brussé, IA; Duvekot, JJ; Grune, F; Sonneveld, MJ; Steegers, EA; Visser, GH, 2014) |
| "The underlying etiology of twin-twin transfusion syndrome (TTTS) is unknown, but our growing understanding of the cardiovascular features of TTTS suggests this may be a disease that could respond to transplacental medical therapy." | 1.40 | Role of adjunctive medical therapy in the fetoscopic surgical treatment of twin-twin transfusion syndrome. ( Crombleholme, TM; Somme, S; Zaretsky, MV, 2014) |
| "Nifedipine is an effective oral tocolytic with few maternal side effects." | 1.40 | [Tocolysis with nifedipin; its use in current practice]. ( Dimitrov, G; Ivanov, S; Jordanova, D; Karamisheva, V; Marinov, B; Nachev, A, 2014) |
| " Moreover, as the combination did not cause severe maternal side effects, it may be considered as a safe and effective method to prolong gestation in patients with preterm labor." | 1.40 | The influence of ritodrine alone or in combination with nifedipine on maternal cardiovascular side effects and pregnancy outcomes. ( Bae, JY; Hwang, I; Kim, MJ; Seong, WJ, 2014) |
| "Risk factors for preterm labor commonly observed in the study group were urinary tract infection (60." | 1.39 | Pregnancy outcomes and successful rate of nifedipine therapeutic protocol implementation in a hospital of San Juan. ( Catalano, LN; Negron, I; Rivera Rosa, E; Vázquez Guzmán, M; Villar Diaz, M, 2013) |
| "Nifedipine was the only aCCB used for this study population." | 1.38 | Antenatal calcium channel blocker exposure and subsequent patent ductus arteriosus in extremely low-birth-weight infants. ( Arzuaga, B; Lee, BH; McGuirl, J, 2012) |
| "Nifedipine was associated with a minimal but significant decrease in blood pressure." | 1.37 | Hypotension in normotensive pregnant women treated with nifedipine as a tocolytic drug. ( Luewan, S; Mahathep, R; Tongsong, T, 2011) |
| "Nilvadipine was administered from P7 to P28." | 1.37 | AAV-mediated gene replacement, either alone or in combination with physical and pharmacological agents, results in partial and transient protection from photoreceptor degeneration associated with betaPDE deficiency. ( Allocca, M; Auricchio, A; Di Vicino, U; Iodice, C; Manfredi, A, 2011) |
| "Pregnancy in patients with chronic renal failure occurs rarely but the incidence is increasing." | 1.37 | Successful management of a high-risk pregnancy with polyhydramnios, IUGR and recurrent pregnancy loss in a chronic renal failure patient: a case report. ( Baykal, C; Kaya, S; Takal, MK; Yakupoğlu, U, 2011) |
| "Takayasu's arteritis is a chronic and non-specific disease of young women in reproductive age that primarily affects the aorta, its branches and the pulmonary artery." | 1.37 | [Takayasu's arteritis in pregnancy: report seven cases]. ( Carvajal-Valencia, JA; Chacón-Solís, AR; Estrada-Altamirano, A; Hernández-Pacheco, JA; Maya-Quiñones, JL; Valenzuela-Jirón, A, 2011) |
| "Pregnancy was extended for more than 48 hours after the first dose of nifedipine in 86." | 1.36 | [Management of pre-term labor: use of nifedipine in Conakry, Guinea]. ( Camara, MK; Cissoko, M; Diallo, A; Diallo, FB; Diallo, MS; Diallo, Y; Lontsi, GR; Sy, T, 2010) |
| "GITS dosage titrated to clinical response (30-150 mg/day)." | 1.35 | Nifedipine concentration in maternal and umbilical cord blood after nifedipine gastrointestinal therapeutic system for tocolysis. ( Juon, AM; Kühn-Velten, WN; Silberschmidt, AL; von Mandach, U; Zimmermann, R, 2008) |
| "Nifedipine is an effective oral tocolytic and a rational alternative to other tocolytic agents in the management of preterm labour." | 1.34 | [Treatment of preterm delivery with calcium channel blockers--Nifedipine]. ( Diavolov, V; Dimitrov, A; Ivanov, S; Markov, D; Nikolov, A, 2007) |
| "Levcromakalim has a vasodilatory effect on the umbilical artery like magnesium sulphate and nifedipine, and serves as an antihypertensive potential that might be used in the treatment of preeclampsia." | 1.34 | Vasorelaxant effect of levcromakalim on isolated umbilical arteries of preeclamptic women. ( Danisman, N; Polat, B; Tufan, H, 2007) |
| "Nifedipine serum levels were measured with liquid chromatography." | 1.34 | Nifedipine serum levels in pregnant women undergoing tocolysis with nifedipine. ( Burkhardt, T; Kraehenmann, F; Marin, TZ; Meier, R; Zimmermann, R, 2007) |
| "Nifedipine is believed to be a superior tocolytic agent on the basis of efficacy and side-effect profile, but was never prospectively evaluated in a placebo-controlled randomized clinical trial (RCT)." | 1.34 | Feasibility of a randomized controlled trial testing nifedipine vs. placebo for the treatment of preterm labor. ( Abenhaim, HA; Audibert, F; Tremblay, L; Tremblay, V, 2007) |
| "Subsequently preeclampsia developed and uteroplacental dysfunction deteriorated." | 1.34 | Severe, early-onset hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome episode with spontaneous remission during pregnancy. ( Gembruch, U; Merz, WM, 2007) |
| "She also had retinal hemorrhages in both eyes and a hemorrhagic infarct in the left occipital lobe that resulted in a permanent right homonymous hemianopia and a persistently depressed acuity of 20/100 OS." | 1.33 | Permanent visual deficits secondary to the HELLP syndrome. ( Ayazifar, M; Murphy, MA, 2005) |
| "The cases had more severe preeclampsia and a longer magnesium sulfate infusion." | 1.33 | Therapy with both magnesium sulfate and nifedipine does not increase the risk of serious magnesium-related maternal side effects in women with preeclampsia. ( Carleton, B; Cheng, C; Côté, AM; Ensom, MH; Li, J; Magee, LA; Miremadi, S; von Dadelszen, P, 2005) |
| "Normal pregnancy is characterized by attenuated vascular reactivity to a variety of contractile agonists and this, in part, has been attributed to increased circulating vasodilators and/or impaired Ca(2+)-influx through L-type Ca(2+)-channels." | 1.33 | Pregnancy-induced modulation of calcium mobilization and down-regulation of Rho-kinase expression contribute to attenuated vasopressin-induced contraction of the rat aorta. ( Katoue, MG; Khan, I; Oriowo, MA, 2006) |
| "Nifedipine maintenance was associated with a significant decline in maternal systolic and diastolic blood pressure after 24 h, while maternal heart rate and FHR were unaffected." | 1.33 | Nifedipine therapy for preterm labor: effects on placental, fetal cerebral and atrioventricular Doppler parameters in the first 48 hours. ( Baschat, AA; Demir, N; Gol, M; Guclu, S; Saygili, U; Sezer, O, 2006) |
| "Posterior reversible encephalopathy syndrome (PRES) is an acronym that identifies a new clinico-neuroradiologic entity occurring in association with different conditions." | 1.33 | PRES: posterior or potentially reversible encephalopathy syndrome? ( Abbate, M; Ferlazzo, E; Granata, F; Mazzù, I; Musolino, R; Narbone, MC, 2006) |
| "To investigate whether women with preeclampsia and abnormal liver function tests have raised serum bile acids." | 1.32 | Preeclampsia with abnormal liver function tests is associated with cholestasis in a subgroup of cases. ( de Swiet, M; Goulis, DG; Redman, CW; Walker, IA; Williamson, C, 2004) |
| "Preterm labor is a major clinical hazard causing both maternal and neonatal morbidity and mortality." | 1.32 | Choosing calcium channel blockers for pregnant women with paroxysmal supraventriclar tachycardia and preterm labor: a case report. ( Lai, WT; Ou, KY; Su, JW; Tsai, EM; Yang, CH, 2004) |
| " The dose-response profile of V(1) receptor agonist-induced neurotrophism exhibited a biphasic function, with lower concentrations inducing a significant increase while higher concentrations generally induced no significant effect." | 1.31 | Vasopressin-induced neurotrophism in cultured neurons of the cerebral cortex: dependency on calcium signaling and protein kinase C activity. ( Brinton, RD; Chen, Q; Kim, J; Monreal, AW; Oji, G; Patel, R; Sales, A, 2000) |
| "Nifedipine treatment reduced mPer1 induction, suggesting that mPer1 mRNA expression depends on intracellular calcium concentration regulated through a voltage-dependent Ca2+ channel." | 1.31 | Calcium and pituitary adenylate cyclase-activating polypeptide induced expression of circadian clock gene mPer1 in the mouse cerebellar granule cell culture. ( Akiyama, M; Minami, Y; Moriya, T; Nakajima, T; Shibata, S, 2001) |
| "Among 21 patients, 26 pulmonary edema attacked, 9 of them had upper have respiratory diseases, thirteen cases caused by improper infusion." | 1.31 | [Analysis of inductive factors, diagnosis and treatment of 21 cases with pregnancy accompanied with pulmonary edema]. ( Wang, S; Zhang, L; Zhao, Y, 2001) |
| "Nifedipine and CGP 28392 treatment of nonpregnant and pregnant animals, respectively, did not modify the response of aortic rings to KCl." | 1.31 | Calcium channels contribute to the decrease in blood pressure of pregnant rats. ( Brochu, M; Cadorette, C; Poterek, M; Simaan, M; St-Louis, J, 2002) |
| "Nifedipine pretreatment had no influence on oxygen delivery in placenta and fetal cerebrum during and after ischemia." | 1.31 | Short therapeutic window for nifedipine in transient intrauterine ischemia in fetal rat brain. ( Araki, T; Koshino, T; Nagano, R; Nakai, A; Oya, A; Shibazaki, Y; Taniuchi, Y, 2002) |
| "Primary pulmonary hypertension is a rare, incurable, and progressive disease." | 1.29 | Primary pulmonary hypertension in pregnancy: a case report. ( Asseryanis, E; Egarter, C; Kiss, H; Kneussl, M; Putz, D, 1995) |
| "[3H]Lacidipine was avidly and promptly entrapped in A7r5 cells and was not removed by washout." | 1.29 | Ca2+ channel blocking activity of lacidipine and amlodipine in A7r5 vascular smooth muscle cells. ( Bachetti, T; Carboni, L; Ferri, S; Ratti, E; Spampinato, S; Van Amsterdam, FT, 1993) |
| "Primary hyperaldosteronism is an uncommon disorder, and there are few reports of its occurrence and management in pregnancy." | 1.29 | Primary hyperaldosteronism in pregnancy. A case report. ( Moore, F; Seely, EW; Solomon, CG; Thiet, M, 1996) |
| "Induction of chemical anoxia, using sodium azide in cerebellar granule cells maintained in primary culture, was evaluated as an in vitro assay for screening of potential neuroprotective compounds." | 1.29 | Characterization of a chemical anoxia model in cerebellar granule neurons using sodium azide: protection by nifedipine and MK-801. ( Drejer, J; Frandsen, A; Schousboe, A; Varming, T, 1996) |
| "Also, patients with superimposed preeclampsia were treated with 40 mg/day oral nifedipine." | 1.28 | Nifedipine treatment in preeclampsia reverts the increased erythrocyte aggregation to normal. ( Boemi, M; De Tommaso, G; Fumelli, P; Garzetti, GG; Lucino, E; Romanini, C; Tranquilli, AL, 1992) |
| "Nifedipine was a well-tolerated and safe tocolytic in this population and warrants further investigation." | 1.28 | Nifedipine for treatment of preterm labor: a historic prospective study. ( Berga, S; Haverkamp, AD; Murray, C; Orleans, M; Pecht, D, 1992) |
| "Bupivacaine is a local anesthetic commonly used in obstetrical practice." | 1.28 | Effects of bupivacaine and calcium antagonists on human uterine arteries in pregnant and non-pregnant women. ( Källfelt, B; Lindblom, B; Norén, H, 1991) |
| "Pharmacokinetic and pharmacodynamic parameters of oral nifedipine were studied in the immediate postpartum period in eight women with preeclampsia." | 1.28 | Nifedipine pharmacokinetics and pharmacodynamics during the immediate postpartum period in patients with preeclampsia. ( Barton, JR; Prevost, RR; Sibai, BM; Whybrew, WD; Wilson, DA, 1991) |
| "Oral nifedipine retard treatment to suppress preterm labour was administered to 8 patients using a new scheme." | 1.28 | Long term treatment with nifedipine retard to suppress preterm labour. ( Ghirardini, G, 1991) |
| "Twenty patients with preeclampsia at a gestational age of 26 to 35 weeks were treated with oral nifedipine until delivery." | 1.28 | The effect of nifedipine therapy on fetal and placental Doppler waveforms in preeclampsia remote from term. ( Akl, S; Fairlie, FM; Khoury, AD; Moretti, MM; Sibai, BM, 1990) |
| " The peak concentration of nifedipine during sublingual therapy ranged from 23." | 1.28 | Nifedipine pharmacokinetics during preterm labor tocolysis. ( Blaschke, T; Ferguson, JE; Pershe, R; Schutz, T; Stevenson, DK, 1989) |
| "Nifedipine was administered to near-term rats and cardiovascular morphology of the fetus was studied with a rapid whole-body freezing technique." | 1.28 | Fetal cardiovascular effects of nifedipine in rats. ( Momma, K; Takao, A, 1989) |
| "[3H] Nitrendipine binding was partially blocked by the presence of tetrodotoxin in developing spinal cord neurons." | 1.27 | TTX displacement of [H3]-nitrendipine binding in developing spinal cord neurons. ( Brenneman, DE; Litzinger, MJ, 1984) |
| "Monensin prevented the increase in thromboplastin activity at 68 hr as well as at 90-96 hr." | 1.27 | Effect of some drugs on thromboplastin activity in mouse trophoblast cells in vitro and in vivo. ( Dalaker, K; Prydz, H, 1986) |
| "Two women with preeclampsia treated unsuccessfully with alpha-methyldopa and magnesium sulfate became profoundly hypotensive when oral nifedipine was added." | 1.27 | Magnesium plus nifedipine: potentiation of hypotensive effect in preeclampsia? ( Cámera, MI; Martinotti, A; Mayorga, LM; Vignolo, CA; Waisman, GD, 1988) |
| "Nifedipine was administered intravenously for 30 minutes to chronically instrumented pregnant ewes." | 1.27 | Nifedipine: effects on fetal and maternal hemodynamics in pregnant sheep. ( Ashwal, S; Gilbert, RD; Harake, B; Power, GG, 1987) |
| "The sensitivity of the uterus to the inhibition of contractions by salbutamol, diltiazem or nifedipine was assessed in the ovariectomized, post-partum rat by dose-response curves following bolus intravenous (i." | 1.27 | The effects of long-term infusion of salbutamol, diltiazem and nifedipine on uterine contractions in the ovariectomized, post-partum rat. ( Abel, MH; Hollingsworth, M, 1986) |
| "Cinnarizine was effective only at a concentration greater than 100 microM." | 1.27 | In vitro effects of calcium entry blockers, chlorpromazine and fenoterol upon human pregnant myometrium contractility. ( Ballejo, G; Calixto, JB; Medeiros, YS, 1986) |
| "We describe a successful, prolonged, inhibition of preterm labor using nifedipine combined with terbutaline in a patient undergoing complicated obstetrical problems." | 1.27 | The management of preterm labor with the calcium channel-blocking agent nifedipine combined with the beta-mimetic terbutaline. ( Friedman, PA; Frigoletto, FD; Kaul, AF; Osathanondh, R; Safon, LE, 1985) |
| "Similarly, when premature labor was induced by ovariectomy (OVX) on day 16, OVX control rats (n = 6) receiving 5 microgram/day of estradiol delivered 82% of the fetuses within 48 hours of OVX, whereas the rats treated with nicardipine (n = 7) delivered only 4% of the fetuses." | 1.26 | Deactivation of the uterus during normal and premature labor by the calcium antagonist nicardipine. ( Csapo, AI; Henzl, MR; Puri, CP; Tarro, S, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 80 (12.20) | 18.7374 |
| 1990's | 153 (23.32) | 18.2507 |
| 2000's | 172 (26.22) | 29.6817 |
| 2010's | 189 (28.81) | 24.3611 |
| 2020's | 62 (9.45) | 2.80 |
| Authors | Studies |
|---|---|
| Lorthe, E | 2 |
| Kayem, G | 2 |
| Mulrenin, IR | 1 |
| Garcia, JE | 1 |
| Fashe, MM | 1 |
| Loop, MS | 1 |
| Daubert, MA | 1 |
| Urrutia, RP | 1 |
| Lee, CR | 2 |
| Earl, RA | 1 |
| Grivell, RM | 1 |
| Ashworth, D | 2 |
| Battersby, C | 2 |
| Green, M | 2 |
| Hardy, P | 2 |
| McManus, RJ | 2 |
| Cluver, C | 1 |
| Chappell, LC | 4 |
| Xiong, Z | 1 |
| Pei, S | 1 |
| Zhu, Z | 2 |
| Yin, J | 1 |
| Mei, Z | 1 |
| Shi, S | 1 |
| Du, P | 1 |
| Qin, S | 1 |
| Wu, HZ | 1 |
| Cheng, Y | 1 |
| Yu, D | 1 |
| Li, JB | 1 |
| Jiang, YF | 1 |
| Zhu, ZN | 1 |
| Dublin, S | 1 |
| Idu, A | 1 |
| Avalos, LA | 1 |
| Cheetham, TC | 1 |
| Easterling, TR | 2 |
| Chen, L | 2 |
| Holt, VL | 1 |
| Nance, N | 1 |
| Bider-Canfield, Z | 1 |
| Neugebauer, RS | 1 |
| Reynolds, K | 1 |
| Badon, SE | 1 |
| Shortreed, SM | 1 |
| Kikuchi, D | 1 |
| Obara, T | 1 |
| Miura, R | 1 |
| Suzuki, N | 1 |
| Hirakawa, H | 1 |
| Josaka, R | 1 |
| Ito, M | 1 |
| Tokunaga, M | 1 |
| Usui, K | 1 |
| Okada, K | 1 |
| Hossain, MR | 1 |
| Tolosa, JM | 2 |
| Young, RC | 4 |
| Smith, R | 3 |
| Paul, JW | 2 |
| van Winden, TMS | 1 |
| Nijman, TAJ | 3 |
| Kleinrouweler, CE | 2 |
| Salim, R | 3 |
| Kashanian, M | 5 |
| Al-Omari, WR | 1 |
| Pajkrt, E | 2 |
| Mol, BW | 21 |
| Oudijk, MA | 15 |
| Roos, C | 10 |
| George, R | 1 |
| Thomas, C | 1 |
| Joy, CA | 1 |
| Varghese, B | 1 |
| Undela, K | 1 |
| Adela, R | 1 |
| Menekse Beser, D | 1 |
| Oluklu, D | 1 |
| Uyan Hendem, D | 1 |
| Yildirim, M | 1 |
| Tugrul Ersak, D | 1 |
| Goncu Ayhan, S | 1 |
| Sahin, D | 1 |
| Greene, NH | 1 |
| Pon, FF | 1 |
| Kilpatrick, SJ | 3 |
| Do, SC | 1 |
| Leonard, SA | 1 |
| Kan, P | 1 |
| Panelli, DM | 1 |
| Girsen, AI | 1 |
| Lyell, DJ | 5 |
| El-Sayed, YY | 5 |
| Druzin, ML | 3 |
| Herrero, T | 1 |
| van de Vusse, D | 1 |
| Mian, P | 1 |
| Schoenmakers, S | 1 |
| Flint, RB | 1 |
| Visser, W | 2 |
| Allegaert, K | 1 |
| Versmissen, J | 1 |
| Taguchi, R | 1 |
| Shigemi, D | 1 |
| Yasunaga, H | 1 |
| Wautlet, CK | 1 |
| Hoffman, MC | 1 |
| Cleary, EM | 1 |
| Racchi, NW | 1 |
| Patton, KG | 1 |
| Kudrimoti, M | 1 |
| Costantine, MM | 3 |
| Rood, KM | 1 |
| Shao, Y | 1 |
| Gu, S | 1 |
| Zhang, X | 3 |
| Kipnis, CM | 1 |
| Daly, PL | 1 |
| Goodwin, ET | 1 |
| Smith, DK | 1 |
| Karadas, B | 2 |
| Acar-Sahan, S | 2 |
| Kantarci, S | 2 |
| Uysal, N | 2 |
| Horoz, E | 2 |
| Kaya-Temiz, T | 2 |
| Fishel Bartal, M | 1 |
| Blackwell, SC | 1 |
| Pedroza, C | 1 |
| Lawal, D | 1 |
| Amro, F | 1 |
| Samuel, J | 1 |
| Chauhan, SP | 5 |
| Sibai, BM | 8 |
| van Wessel, S | 1 |
| Rombaut, J | 1 |
| Vanhulle, A | 1 |
| Emanuel, MH | 1 |
| Hamerlynck, T | 1 |
| Weyers, S | 1 |
| Arman, BM | 1 |
| Binder, NK | 1 |
| de Alwis, N | 1 |
| Beard, S | 1 |
| Debruin, DA | 1 |
| Hayes, A | 1 |
| Tong, S | 1 |
| Kaitu'u-Lino, TJ | 1 |
| Hannan, NJ | 1 |
| S, D | 1 |
| Novri, DA | 1 |
| Hamidy, Y | 1 |
| Savira, M | 1 |
| El-Malkey, NF | 1 |
| Aref, M | 1 |
| Goda, NIA | 1 |
| Hussien, MH | 1 |
| Samy, W | 1 |
| Hadhod, S | 1 |
| Ou, M | 1 |
| Zhang, F | 1 |
| Cui, S | 1 |
| Zhao, S | 1 |
| Yu, Y | 1 |
| Bajpai, D | 1 |
| Popa, C | 1 |
| Verma, P | 1 |
| Dumanski, S | 1 |
| Shah, S | 1 |
| Al-Thuwaynee, S | 1 |
| Bick, D | 1 |
| Leighton, L | 1 |
| Magee, LA | 6 |
| Maher, A | 1 |
| Moakes, C | 1 |
| Morris, RK | 1 |
| Nelson-Piercy, C | 3 |
| Sparkes, J | 1 |
| Rivero-Arias, O | 1 |
| Webb, A | 1 |
| Wilson, H | 1 |
| Myers, J | 1 |
| Yoselevsky, EM | 1 |
| Seely, EW | 2 |
| Celi, AC | 1 |
| Robinson, JN | 1 |
| McElrath, TF | 1 |
| Bhat, AD | 1 |
| Keasler, PM | 1 |
| Kolluru, L | 1 |
| Dombrowski, MM | 1 |
| Palanisamy, A | 1 |
| Singh, PM | 1 |
| Peng, Z | 1 |
| Zhang, J | 1 |
| Xiao, Y | 1 |
| Dong, W | 1 |
| Wei, Y | 1 |
| Wang, Y | 2 |
| Yao, Q | 2 |
| Zhou, L | 3 |
| Fu, P | 1 |
| Al-Jarallah, A | 1 |
| Oommen, E | 1 |
| Chacko Verghese, L | 1 |
| Oriowo, MA | 2 |
| Webster, LM | 2 |
| Reed, K | 1 |
| Myers, JE | 3 |
| Burns, A | 1 |
| Gupta, P | 1 |
| Patel, P | 1 |
| Wiesender, C | 1 |
| Seed, PT | 2 |
| Salama, M | 1 |
| Rezk, M | 3 |
| Gaber, W | 1 |
| Hamza, H | 1 |
| Marawan, H | 1 |
| Gamal, A | 1 |
| Abdallah, S | 1 |
| Inan, C | 1 |
| Sayin, C | 1 |
| Dolgun, N | 1 |
| Uzun, I | 1 |
| Erzincan, SG | 1 |
| Sutcu, H | 1 |
| Varol, F | 1 |
| Levin, G | 2 |
| Ezra, Y | 1 |
| Weill, Y | 1 |
| Kabiri, D | 1 |
| Pollack, RN | 1 |
| Rottenstreich, A | 2 |
| Soares, C | 1 |
| Gilson, M | 1 |
| Alavifard, S | 1 |
| Chase, R | 1 |
| Janoudi, G | 1 |
| Chaumont, A | 1 |
| Lanes, A | 1 |
| Walker, M | 1 |
| Gaudet, L | 1 |
| Santos, S | 1 |
| Haslinger, C | 1 |
| Mennet, M | 1 |
| von Mandach, U | 3 |
| Hamburger, M | 1 |
| Simões-Wüst, AP | 1 |
| Leal-Júnior, CC | 1 |
| Amorim, MMR | 1 |
| Souza, GFA | 1 |
| Lima, AKS | 1 |
| Souza, ASR | 1 |
| Saade, GR | 6 |
| Alanne, L | 1 |
| Bhide, A | 1 |
| Hoffren, J | 1 |
| Lantto, J | 1 |
| Huhta, H | 1 |
| Kokki, M | 1 |
| Haapsamo, M | 1 |
| Acharya, G | 1 |
| Räsänen, J | 1 |
| Kantorowska, A | 1 |
| Heiselman, CJ | 1 |
| Halpern, TA | 1 |
| Akerman, MB | 1 |
| Elsayad, A | 1 |
| Muscat, JC | 1 |
| Sicuranza, GB | 1 |
| Vintzileos, AM | 1 |
| Heo, HJ | 1 |
| van Winden, T | 1 |
| Klumper, J | 1 |
| Tichelaar, MA | 1 |
| Naaktgeboren, CA | 2 |
| Nijman, TA | 2 |
| van Baar, AL | 1 |
| van Wassenaer-Leemhuis, AG | 2 |
| Roseboom, TJ | 1 |
| Van't Hooft, J | 1 |
| Bellos, I | 1 |
| Pergialiotis, V | 1 |
| Papapanagiotou, A | 1 |
| Loutradis, D | 1 |
| Daskalakis, G | 1 |
| Thornton, JG | 2 |
| Ekawati, FM | 1 |
| Lau, P | 1 |
| Wu, Y | 2 |
| Wang, DJ | 1 |
| Zhang, Y | 1 |
| Zhang, YX | 1 |
| Zhang, R | 1 |
| Tolcher, MC | 1 |
| Fox, KA | 1 |
| Sangi-Haghpeykar, H | 1 |
| Clark, SL | 1 |
| Belfort, MA | 3 |
| Thakur, M | 2 |
| Gainder, S | 2 |
| Saha, SC | 2 |
| Prakash, M | 2 |
| Yilmaz, O | 1 |
| Göncü, AŞ | 1 |
| Doherty, A | 1 |
| McLaughlin, K | 1 |
| Kingdom, JC | 1 |
| Khatri, R | 1 |
| Kulick, N | 1 |
| Rementer, RJB | 1 |
| Fallon, JK | 1 |
| Sykes, C | 1 |
| Schauer, AP | 1 |
| Malinen, MM | 1 |
| Mosedale, M | 1 |
| Watkins, PB | 1 |
| Kashuba, ADM | 1 |
| Boggess, KA | 1 |
| Smith, PC | 1 |
| Brouwer, KLR | 1 |
| Emeruwa, UN | 1 |
| Krenitsky, NM | 1 |
| Sheen, JJ | 1 |
| Martin, C | 1 |
| Pappas, J | 1 |
| Johns, K | 1 |
| Figueroa, H | 1 |
| Balli, K | 1 |
| Yao, R | 1 |
| Hyuga, S | 1 |
| Parry, RC | 1 |
| Danielsson, J | 1 |
| Vink, J | 1 |
| Fu, XW | 1 |
| Wu, A | 1 |
| Dan, W | 1 |
| Yim, PD | 1 |
| Gallos, G | 1 |
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| Laish-Farkash, A | 1 |
| Bruoha, S | 1 |
| Rabinovich, M | 1 |
| Harlev, A | 1 |
| Anteby, E | 1 |
| Yosefy, C | 1 |
| Shenhav, S | 1 |
| Yasuda, K | 1 |
| Yoshida, A | 1 |
| Okada, H | 1 |
| Mulder, EG | 1 |
| Ghossein-Doha, C | 1 |
| Cauffman, E | 1 |
| Lopes van Balen, VA | 1 |
| Schiffer, VMMM | 1 |
| Alers, RJ | 1 |
| Oben, J | 1 |
| Smits, L | 1 |
| van Kuijk, SMJ | 1 |
| Spaanderman, MEA | 1 |
| Sharma, A | 3 |
| Nakade, UP | 3 |
| Akash, R | 1 |
| Yadav, VP | 1 |
| Choudhury, S | 3 |
| Jaitley, P | 1 |
| Sharma, V | 1 |
| Garg, SK | 3 |
| Ibrahim, MH | 1 |
| Elfaki, T | 1 |
| Elhassan, EM | 1 |
| Abdelrahiem, SK | 1 |
| Adam, I | 1 |
| Hawkins, JS | 1 |
| Wells, CE | 1 |
| Casey, BM | 1 |
| McIntire, DD | 1 |
| Leveno, KJ | 1 |
| Verspyck, E | 2 |
| de Vienne, C | 1 |
| Muszynski, C | 1 |
| Bubenheim, M | 1 |
| Chanavaz-Lacheray, I | 1 |
| Dreyfus, M | 1 |
| Deruelle, P | 1 |
| Benichou, J | 1 |
| Mary, S | 1 |
| Small, HY | 2 |
| Siwy, J | 1 |
| Mullen, W | 1 |
| Giri, A | 1 |
| Delles, C | 2 |
| Sharma, KJ | 1 |
| Xiao, X | 1 |
| Xiao, F | 1 |
| Zhao, M | 2 |
| Tong, M | 1 |
| Wise, MR | 1 |
| Stone, PR | 3 |
| Chamley, LW | 3 |
| Chen, Q | 4 |
| Goedhart, MM | 1 |
| Naaktgeboren, CN | 1 |
| de Haan, TR | 1 |
| Vijlbrief, DC | 1 |
| Benders, MJN | 1 |
| Franx, A | 6 |
| Duro-Gómez, J | 1 |
| Rodríguez-Marín, AB | 1 |
| Giménez de Azcárete, M | 1 |
| Duro-Gómez, L | 1 |
| Hernández-Angeles, C | 1 |
| Arjona-Berral, JE | 1 |
| Castelo-Branco, C | 1 |
| Shi, DD | 2 |
| Guo, JJ | 1 |
| Wang, N | 2 |
| Xiao, S | 1 |
| Zhang, M | 4 |
| Liang, Y | 1 |
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| Aggarwal, A | 1 |
| Bagga, R | 2 |
| Girish, B | 1 |
| Kalra, J | 1 |
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| Sharma, C | 2 |
| Soni, A | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Tocolysis in the Management of Preterm Premature Rupture of Membranes Before 34 Weeks of Gestation: a Double-blinded Randomized Controlled Trial[NCT03976063] | Phase 3 | 850 participants (Anticipated) | Interventional | 2019-10-07 | Recruiting | ||
| Nifedipine XL Versus Placebo for the Treatment of Preeclampsia With Severe Features During Induction of Labor[NCT04392375] | Phase 4 | 110 participants (Actual) | Interventional | 2020-06-09 | Completed | ||
| Bryophyllum Pinnatum Treatment of Anxiety Related to Signs of Preterm Birth: a Randomised, Double-blind, Placebo-controlled Study as Investigator-Initiated Trial[NCT05110599] | Phase 2 | 60 participants (Actual) | Interventional | 2022-07-12 | Terminated (stopped due to Slow recruitment and expired study medication.) | ||
| Early Vascular Adjustments to Prevent Preeclampsia and Related Complications[NCT04216706] | 314 participants (Actual) | Observational | 2014-11-01 | Completed | |||
| Nifedipine for Acute Tocolysis of Preterm Labor[NCT02132533] | Phase 3 | 88 participants (Actual) | Interventional | 2014-05-05 | Completed | ||
| A Randomized Control Trial of Furosemide or Placebo With Usual Antihypertensives in the Antepartum Management of Severe Hypertension With Wide Pulse Pressure[NCT04615624] | Phase 3 | 65 participants (Actual) | Interventional | 2021-01-04 | Completed | ||
| Maintenance Oral Nifedipine for Management of Symptomatic Placenta Previa : A Randomized Clinical Trial[NCT00620724] | Phase 2 | 109 participants (Actual) | Interventional | 2008-01-31 | Completed | ||
| Oral Antihypertensive Regimens for Management of Hypertension in Pregnancy[NCT01912677] | Phase 4 | 894 participants (Actual) | Interventional | 2015-04-30 | Completed | ||
| Use of Sildenafil Citrate in Management of Mild Pre-eclampsia: A Randomized Controlled Trial[NCT03262961] | Phase 2/Phase 3 | 80 participants (Anticipated) | Interventional | 2016-09-15 | Recruiting | ||
| Vaginal Indomethacin Versus Oral Nifedipine for Preterm Labor; a Randomized Controlled Trial[NCT04404686] | Phase 2/Phase 3 | 300 participants (Anticipated) | Interventional | 2020-10-31 | Not yet recruiting | ||
| The Tocolytic Efficacy of Nifedipine in the Management of Threatened and Advanced Preterm Labor: A Study on 444 Singleton Pregnant Women With Intact Membranes[NCT04644354] | 444 participants (Anticipated) | Observational | 2020-12-15 | Not yet recruiting | |||
| Lasix for the Prevention of De Novo Postpartum Hypertension: A Randomized Controlled Trial (LAPP Trial)[NCT04752475] | Phase 3 | 82 participants (Actual) | Interventional | 2021-10-20 | Completed | ||
| Postpartum Management of Gestational Hypertensive Disorders Using Furosemide: A Randomized Controlled Trial[NCT04343235] | Phase 4 | 13 participants (Actual) | Interventional | 2020-05-01 | Terminated (stopped due to Challenges with enrollment; primary investigator left the institution) | ||
| Nifedipine for the Maintenance Tocolysis of Preterm Labor: Comparison to Placebo in a Prospective, Randomized Double Blind Trial[NCT00185952] | 70 participants (Actual) | Interventional | 2001-11-30 | Completed | |||
| Vaginal Progesterone for the Prevention of Preterm Birth in Women With Arrested Preterm Labor[NCT01840228] | 38 participants (Actual) | Interventional | 2013-05-31 | Terminated (stopped due to Low enrollment rate) | |||
| Randomized, Placebo Controlled Trial of Indomethacin for Tocolysis[NCT01869361] | Early Phase 1 | 0 participants (Actual) | Interventional | 2020-08-01 | Withdrawn (stopped due to Due to much lower than expected numbers of eligible patients and lack of PI time, the study was not started.) | ||
| Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)[NCT02409680] | 11,976 participants (Actual) | Interventional | 2016-03-23 | Completed | |||
| Nifedipine Compared to Atosiban for Treating Preterm Labor. A Randomized Controlled Trial.[NCT00599898] | Phase 4 | 145 participants (Actual) | Interventional | 2008-01-31 | Completed | ||
| Labetalol Versus MgSO4 for the Prevention of Eclampsia Trial (LAMPET)[NCT00293735] | Phase 2/Phase 3 | 0 participants (Actual) | Interventional | 2015-06-30 | Withdrawn (stopped due to Lack of funding) | ||
| A Novel Protocol for Postpartum Magnesium Sulfate in Severe Preeclampsia When the Woman Received Less That 8 Hours Before Delivery. Six Versus Twenty-four Hours Postpartum[NCT02317146] | Phase 2/Phase 3 | 280 participants (Actual) | Interventional | 2013-11-30 | Completed | ||
| Magnesium Sulfate During the Postpartum in Women With Severe Preeclampsia Receiving Treatment for More Than 8 Hours Before Delivery. A Randomized Multicenter Clinical Trial .[NCT02307201] | Phase 2/Phase 3 | 1,114 participants (Actual) | Interventional | 2014-12-31 | Completed | ||
| A Comparison of Fetal Hemodynamic Measurements Between Pregnant Women Taking Anti-hypertensive Medication and Controls[NCT00759278] | 0 participants (Actual) | Observational | 2008-08-31 | Withdrawn (stopped due to No participants) | |||
| Magnesium Sulfate Versus Nifedipine for the Acute Tocolysis of Preterm Labor: A Prospective, Randomized Trial[NCT00185900] | 192 participants (Actual) | Interventional | 1999-04-30 | Completed | |||
| The Endocannabinoid System in Human Gestational Tissues in Labor[NCT03752021] | 20 participants (Actual) | Observational | 2019-01-25 | Completed | |||
| Randomized Double-Blinded Trial of Magnesium Sulfate Tocolysis Versus Nifedipine Tocolysis in Women With Preterm Labor Between 24 to 32 6/7 Weeks' Gestation[NCT00306462] | 33 participants (Actual) | Interventional | 2006-03-31 | Terminated (stopped due to No enrollment in past year, lack of interest) | |||
| Will Reduction in Plasma Sodium Reduce Myometrium Contractility in Humans? An Invitro Study of Pregnant Myometrium at Term.[NCT01708811] | 12 participants (Actual) | Observational | 2012-10-31 | Terminated (stopped due to Few biopsies showed the expected pattern We suspect erroeneous method.) | |||
| Is Procardia XL 60 mg Q Daily Equivalent to 30 mg XL Given Twice Daily?[NCT03595982] | Phase 4 | 5 participants (Actual) | Interventional | 2018-09-15 | Terminated (stopped due to Low enrollment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT04392375)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Nifedipine 30MG | 20 |
| Placebo | 19 |
(NCT04392375)
Timeframe: Between enrollment and delivery, assessed up to 18 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Nifedipine 30MG | 8 |
| Placebo | 6 |
Measured acute antihypertension therapy between enrollment and delivery (NCT04392375)
Timeframe: Between enrollment and delivery, assessed up to 18 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Nifedipine 30MG | 18 |
| Placebo | 27 |
(NCT04392375)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Cesarean Delivery | Vaginal Delivery | |
| Nifedipine 30MG | 11 | 42 |
| Placebo | 17 | 32 |
Some participants could have more than one indication for Cesarean Delivery. (NCT04392375)
Timeframe: Between enrollment and delivery, assessed up to 18 weeks
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| First stage arrest | Second stage arrest | Nonreassuring fetal status | Worsening maternal status | |
| Nifedipine 30MG | 8 | 1 | 3 | 2 |
| Placebo | 6 | 5 | 7 | 1 |
(NCT02132533)
Timeframe: At least 2 doses of betamethasone administered prior to delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Nifedipine | 36 |
| Placebo | 31 |
(NCT02132533)
Timeframe: Less than 37 weeks of gestation
| Intervention | Participants (Count of Participants) |
|---|---|
| Nifedipine | 24 |
| Placebo | 20 |
(NCT02132533)
Timeframe: Within 48 hours of randomization
| Intervention | Participants (Count of Participants) |
|---|---|
| Nifedipine | 8 |
| Placebo | 10 |
(NCT02132533)
Timeframe: Within 7 days of randomization
| Intervention | Participants (Count of Participants) |
|---|---|
| Nifedipine | 13 |
| Placebo | 14 |
Difference in MAP averaged over the 24 hours prior to discharge or the 24 hours prior to antihypertensive therapy initiation (whichever occurs first) (NCT04752475)
Timeframe: 24 hours prior to discharge through discharge, up to 7 days
| Intervention | mmHg (Mean) |
|---|---|
| Lasix (Furosemide) | 88.9 |
| Placebo | 86.8 |
breastfeeding continuation after discharge (NCT04343235)
Timeframe: at 1 week postpartum visit
| Intervention | Participants (Count of Participants) |
|---|---|
| Labetalol + Furosemide | 1 |
| Labetalol Only | 3 |
number of patients who require a change in the dose of labetalol to control BP (NCT04343235)
Timeframe: Change in dose of hypertensive therapy from randomization until hospital discharge (up to 7 days)
| Intervention | Participants (Count of Participants) |
|---|---|
| Labetalol + Furosemide | 3 |
| Labetalol Only | 0 |
days in hospital after delivery (NCT04343235)
Timeframe: Number of days of hospital stay from randomization to discharge
| Intervention | days (Mean) |
|---|---|
| Labetalol + Furosemide | 3.5 |
| Labetalol Only | 4.3 |
readmission for hypertension management (NCT04343235)
Timeframe: up to 14 days after discharge
| Intervention | Participants (Count of Participants) |
|---|---|
| Labetalol + Furosemide | 1 |
| Labetalol Only | 2 |
average diastolic blood pressure reading on Day 0, Day 1, and Day 2 (NCT04343235)
Timeframe: Average diastolic blood pressure on Day 0, Day 1, and Day 2
| Intervention | mm of mercury (Mean) | ||
|---|---|---|---|
| Day 0 | Day 1 | Day 2 | |
| Labetalol + Furosemide | 84.1 | 81.8 | 78.8 |
| Labetalol Only | 80.1 | 80.7 | 75.5 |
average mean arterial pressure reading on Day 0, Day 1, and Day 2 (NCT04343235)
Timeframe: Average mean arterial pressure on Day 0, Day 1, and Day 2
| Intervention | mm of mercury (Mean) | ||
|---|---|---|---|
| Day 0 | Day 1 | Day 2 | |
| Labetalol + Furosemide | 102.4 | 99.5 | 98.0 |
| Labetalol Only | 100.0 | 100.1 | 96.0 |
average systolic blood pressure reading on Day 0, Day 1, and Day 2 (NCT04343235)
Timeframe: Average systolic blood pressure for Day 0, Day 1, and Day 2
| Intervention | mm of mercury (Mean) | ||
|---|---|---|---|
| Day 0 | Day 1 | Day 2 | |
| Labetalol + Furosemide | 138.4 | 134.9 | 135.2 |
| Labetalol Only | 138.1 | 138.2 | 136.7 |
A composite neonatal outcome comprising neonatal death, respiratory distress syndrome, bronchopulmonary dysplasia, severe (grade III/IV) interventricular hemorrhage, necrotizing enterocolitis, and sepsis. (NCT01840228)
Timeframe: Followed for duration of neonatal hospital stay, estimated maximum 16 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Micronized Progesterone Suppository - SINGLETON | 5 |
| Placebo Suppository - SINGLETON | 5 |
| Micronized Progesterone Suppository - TWINS | 3 |
| Placebo Suppository - TWINS | 7 |
(NCT01840228)
Timeframe: 2 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Micronized Progesterone Suppository | 6 |
| Placebo Suppository | 4 |
(NCT01840228)
Timeframe: Day of delivery in current pregnancy
| Intervention | grams (Mean) |
|---|---|
| Micronized Progesterone Suppository - SINGLETON | 2454.9 |
| Placebo Suppository - SINGLETON | 2523.1 |
| Micronized Progesterone Suppository - TWINS | 2164.4 |
| Placebo Suppository - TWINS | 1974.1 |
(NCT01840228)
Timeframe: Followed for duration of neonatal hospital stay, estimated maximum 16 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Micronized Progesterone Suppository - SINGLETON | 2 |
| Placebo Suppository - SINGLETON | 2 |
| Micronized Progesterone Suppository - TWINS | 0 |
| Placebo Suppository - TWINS | 1 |
Evaluated in women enrolled prior to 32 weeks gestation (NCT01840228)
Timeframe: Duration of current pregnancy, anticipated maximum 18 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Micronized Progesterone Suppository | 3 |
| Placebo Suppository | 6 |
(NCT01840228)
Timeframe: Duration of current pregnancy, anticipated maximum 18 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Micronized Progesterone Suppository | 11 |
| Placebo Suppository | 10 |
(NCT01840228)
Timeframe: Duration of current pregnancy, anticipated maximum 18 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Micronized Progesterone Suppository | 0 |
| Placebo Suppository | 0 |
(NCT01840228)
Timeframe: Duration of current pregnancy, anticipated maximum 18 weeks
| Intervention | weeks (Median) |
|---|---|
| Micronized Progesterone Suppository | 5.3 |
| Placebo Suppository | 5.0 |
- Early preterm delivery (<34 weeks) (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 189 |
| Placebo Arm | 230 |
- Birth weight <2500g (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 1078 |
| Placebo Arm | 1153 |
- Birth weight <1500g (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 78 |
| Placebo Arm | 101 |
- Incidence of Fetal Loss (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 303 |
| Placebo Arm | 353 |
- Incidence of Spontaneous Abortion (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 134 |
| Placebo Arm | 152 |
- Incidence of All stillbirth (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 141 |
| Placebo Arm | 166 |
- Incidence of Medical Termination of Pregnancy (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 42 |
| Placebo Arm | 30 |
- Hypertensive disorders of pregnancy is defined by the characterization of evidence of a hypertensive disorder, including either preeclampsia or eclampsia occurring during the pregnancy. (NCT02409680)
Timeframe: Evidence of hypertensive disorder during the pregnancy (prior to delivery/birth)
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 352 |
| Placebo Arm | 325 |
- Incidence of Perinatal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 264 |
| Placebo Arm | 309 |
The primary outcome of this study is incidence of preterm birth, which will be defined as delivery at or after 20 0/7 weeks and prior to 37 0/7 weeks. This will be determined based on actual date of delivery in comparison to the projected estimated due date (EDD), independent of whether or not the preterm delivery is indicated or spontaneous. (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 668 |
| Placebo Arm | 754 |
- Small for gestational age (SGA) as defined by the INTERGROWTH-21st standard (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 1506 |
| Placebo Arm | 1564 |
- Vaginal bleeding (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 214 |
| Placebo Arm | 246 |
- Antepartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 26 |
| Placebo Arm | 25 |
- Postpartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 54 |
| Placebo Arm | 43 |
- Incidence of Maternal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 9 |
| Placebo Arm | 12 |
- Incidence of Late Abortion (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 23 |
| Placebo Arm | 30 |
Hemoglobin < 7.0 gm/dl at 26-30 weeks gestation or a drop of 3.5+ gm/dl from screening to 26-30 weeks gestation (NCT02409680)
Timeframe: At enrollment, 4 weeks post enrollment, and 26-30 weeks GA.
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 290 |
| Placebo Arm | 333 |
Early preterm delivery (<34 weeks) and hypertensive disorders (i.e.: preeclampsia) (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 8 |
| Placebo Arm | 21 |
Defined as any of the following: respiratory distress syndrome, intraventricular hemorrhage, necrotizing enterocolitis, sepsis or fetal/neonatal death. (NCT00185900)
Timeframe: From delivery until discharge from the hospital, up to 30 days of age
| Intervention | Participants (Count of Participants) |
|---|---|
| Magnesium Sulfate | 27 |
| Nifedipine | 22 |
Presented as weeks (NCT00185900)
Timeframe: Until delivery, up to 42 weeks of gestation
| Intervention | weeks (Mean) |
|---|---|
| Magnesium Sulfate | 35.8 |
| Nifedipine | 36.0 |
Presented as grams (NCT00185900)
Timeframe: Until delivery, up to 42 weeks of gestation
| Intervention | grams (Mean) |
|---|---|
| Magnesium Sulfate | 2550 |
| Nifedipine | 2650 |
Uterine quiescence defined by 12 hours of six or fewer contractions per hour and no further cervical change within 48 hours of tocolytic initiation. (NCT00185900)
Timeframe: 48 hours after administration of study medication.
| Intervention | Participants (Count of Participants) |
|---|---|
| Magnesium Sulfate | 80 |
| Nifedipine | 72 |
A composite of any of the following: chest pain, pulmonary edema, shortness of breath or hypotension. (NCT00185900)
Timeframe: From study enrollment until discharge from delivery hospital, up to 30 days after delivery.
| Intervention | Participants (Count of Participants) |
|---|---|
| Magnesium Sulfate | 20 |
| Nifedipine | 10 |
Uterine quiescence was defined by 12 hours of six of fewer contractions per hour and no further cervical change. (NCT00185900)
Timeframe: Until delivery, up to 42 weeks of gestation
| Intervention | hours (Mean) |
|---|---|
| Magnesium Sulfate | 8.4 |
| Nifedipine | 6.1 |
Survey to assess Frequency of side effects of nifedipine including peripheral edema (most common side effect, dose related), flushing, headache, dizziness, fatigue, constipation, nausea, and muscle cramps. (NCT03595982)
Timeframe: up to 24 hours
| Intervention | events (Number) |
|---|---|
| Procardia XL 30 mg | 1 |
| Procardia XL 60 mg | 2 |
Blood pressure reading (NCT03595982)
Timeframe: up to 24 hours
| Intervention | mmHg (Mean) | |
|---|---|---|
| Systolic | Diastolic | |
| Procardia XL 30 mg | 155 | 92 |
| Procardia XL 60 mg | 146 | 84 |
98 reviews available for nifedipine and Pregnancy
| Article | Year |
|---|---|
The Impact of Pregnancy on Antihypertensive Drug Metabolism and Pharmacokinetics: Current Status and Future Directions.
Topics: Antihypertensive Agents; Female; Humans; Hypertension, Pregnancy-Induced; Labetalol; Nifedipine; Pha | 2021 |
Nifedipine for primary dysmenorrhoea.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dysmenorrhea; Female; Humans; Infant, Newborn; Menstruation | 2021 |
Four kinds of tocolytic therapy for preterm delivery: Systematic review and network meta-analysis.
Topics: Female; Humans; Indomethacin; Infant; Infant, Newborn; Network Meta-Analysis; Nifedipine; Obstetric | 2022 |
Nifedipine or amlodipine? The choice for hypertension during pregnancy: a systematic review and meta-analysis.
Topics: Amlodipine; Female; Humans; Hypertension; Infant, Newborn; Nifedipine; Obstetric Labor, Premature; P | 2022 |
Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials.
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Hypertension, Pr | 2022 |
Tocolysis with nifedipine versus atosiban and perinatal outcome: an individual participant data meta-analysis.
Topics: Female; Humans; Infant, Newborn; Nifedipine; Perinatal Death; Pregnancy; Premature Birth; Systematic | 2022 |
Comparative efficacy and safety of oral nifedipine with other antihypertensive medications in the management of hypertensive disorders of pregnancy: a systematic review and meta-analysis of randomized controlled trials.
Topics: Antihypertensive Agents; Female; Humans; Hypertension, Pregnancy-Induced; Nifedipine; Pregnancy; Pre | 2022 |
Pharmacokinetics of the most commonly used antihypertensive drugs throughout pregnancy methyldopa, labetalol, and nifedipine: a systematic review.
Topics: Antihypertensive Agents; Female; Humans; Hypertension; Hypertension, Pregnancy-Induced; Labetalol; M | 2022 |
Hypertensive Crisis in Pregnancy.
Topics: Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension; Labetalol; Nifedipine; Pregnancy | 2022 |
Oral nifedipine may be a preferential option for treating acute severe hypertension during pregnancy: a meta-analysis.
Topics: Blood Pressure; Female; Humans; Hypertension, Pregnancy-Induced; Labetalol; Nifedipine; Pregnancy | 2023 |
Evaluation and Management of Hypertensive Disorders of Pregnancy.
Topics: Antihypertensive Agents; Female; Humans; Hypertension, Pregnancy-Induced; Infant, Newborn; Labetalol | 2023 |
Treatment of acute-onset hypertension in pregnancy: A network meta-analysis of randomized controlled trials comparing anti-hypertensives and route of administration.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hydralazine; Hypertension; Infant | 2023 |
First-line antihypertensive treatment for severe hypertension in pregnancy: A systematic review and network meta-analysis.
Topics: Antihypertensive Agents; Female; Humans; Hypertension, Pregnancy-Induced; Nifedipine; Pregnancy; Pre | 2019 |
Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis.
Topics: Abruptio Placentae; Amlodipine; Antihypertensive Agents; Atenolol; Cesarean Section; Chronic Disease | 2020 |
Hemodynamic Complications in Pregnancy: Preeclampsia and Beyond.
Topics: Anticonvulsants; Antihypertensive Agents; Aspirin; Delivery, Obstetric; Female; Fetal Growth Retarda | 2020 |
Advances in Management for Preterm Fetuses at Risk of Delivery.
Topics: Anti-Bacterial Agents; Anticonvulsants; Betamethasone; Dexamethasone; Female; Fetal Membranes, Prema | 2020 |
Postpartum Hypertension: Etiology, Diagnosis, and Management.
Topics: Antihypertensive Agents; Blood Pressure; Disease Management; Female; Humans; Hydralazine; Hypertensi | 2017 |
Maintaining and repeating tocolysis: A reflection on evidence.
Topics: Drug Administration Schedule; Evidence-Based Practice; Female; Humans; Nifedipine; Obstetric Labor, | 2017 |
Focused Update on Pharmacologic Management of Hypertensive Emergencies.
Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Brain Ischemia; Emergencies; Enalapri | 2018 |
Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials.
Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Female; Headache; Humans; Hydralazine; Hy | 2018 |
Prevention of Prematurity: Advances and Opportunities.
Topics: Anti-Infective Agents; Aspirin; Cerclage, Cervical; Cesarean Section; Female; Humans; Indomethacin; | 2018 |
Systematic review and meta-analysis of randomized controlled trials of atosiban versus nifedipine for inhibition of preterm labor.
Topics: Adult; Female; Humans; Nifedipine; Obstetric Labor, Premature; Odds Ratio; Pregnancy; Randomized Con | 2019 |
Hypertension and Pregnancy: Management and Future Risks.
Topics: Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Chronic Disease; Diuretics; Female; Human | 2019 |
Hypertensive emergencies of pregnancy.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Creatine; Diuretics; Emergency Medicine; Female; | 2013 |
Transdermal nitroglycerin for the treatment of preterm labor: a systematic review and metaanalysis.
Topics: Administration, Cutaneous; Adrenergic beta-2 Receptor Agonists; Female; Humans; Magnesium Sulfate; N | 2013 |
Severe pre-eclampsia and hypertensive crises.
Topics: Administration, Intravenous; Administration, Oral; Antihypertensive Agents; Critical Care; Early Dia | 2013 |
Maintenance therapy with calcium channel blockers for preventing preterm birth after threatened preterm labour.
Topics: Calcium Channel Blockers; Female; Humans; Incidence; Infant Mortality; Infant, Newborn; Labor, Obste | 2013 |
Twin pregnancy after kidney transplantation: what's on? A case report and review of literature.
Topics: Adult; Anemia; Female; Humans; Hypertension, Pregnancy-Induced; Iron; Kidney Transplantation; Methyl | 2014 |
Preterm labor: current pharmacotherapy options for tocolysis.
Topics: Female; Humans; Infant, Newborn; Nifedipine; Obstetric Labor, Premature; Pregnancy; Premature Birth; | 2014 |
Tocolytics for preterm premature rupture of membranes.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Bacterial Agents; Female; Fetal Membranes, P | 2014 |
Oral antihypertensive therapy for severe hypertension in pregnancy and postpartum: a systematic review.
Topics: Administration, Oral; Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension, Pregnancy- | 2014 |
Calcium channel blockers for inhibiting preterm labour and birth.
Topics: Adrenergic beta-Agonists; Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Pre | 2014 |
Calcium channel blockers for inhibiting preterm labour and birth.
Topics: Adrenergic beta-Agonists; Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Pre | 2014 |
Calcium channel blockers for inhibiting preterm labour and birth.
Topics: Adrenergic beta-Agonists; Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Pre | 2014 |
Calcium channel blockers for inhibiting preterm labour and birth.
Topics: Adrenergic beta-Agonists; Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Pre | 2014 |
Calcium channel blockers for inhibiting preterm labour and birth.
Topics: Adrenergic beta-Agonists; Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Pre | 2014 |
Calcium channel blockers for inhibiting preterm labour and birth.
Topics: Adrenergic beta-Agonists; Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Pre | 2014 |
Calcium channel blockers for inhibiting preterm labour and birth.
Topics: Adrenergic beta-Agonists; Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Pre | 2014 |
Calcium channel blockers for inhibiting preterm labour and birth.
Topics: Adrenergic beta-Agonists; Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Pre | 2014 |
Calcium channel blockers for inhibiting preterm labour and birth.
Topics: Adrenergic beta-Agonists; Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Pre | 2014 |
Hypertensive emergencies in pregnancy.
Topics: Antihypertensive Agents; Eclampsia; Emergencies; Female; Humans; Hydralazine; Hypertension; Hyperten | 2014 |
Oral nifedipine versus intravenous labetalol for the treatment of severe hypertension in pregnancy.
Topics: Administration, Oral; Antihypertensive Agents; Female; Humans; Hypertension; Infusions, Intravenous; | 2015 |
[Maintenance tocolysis with calcium channel blockers].
Topics: Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnan | 2015 |
[Calcium channel blockers pharmacology and their use as tocolytics].
Topics: Adult; Calcium Channel Blockers; Female; Humans; Nicardipine; Nifedipine; Obstetric Labor, Premature | 2015 |
[Use of calcium channel blockers (CCB) for tocolysis in France and abroad].
Topics: Adult; Calcium Channel Blockers; Female; France; Hospitals, Maternity; Humans; Nifedipine; Obstetric | 2015 |
Oral nifedipine versus intravenous labetalol for severe hypertension during pregnancy: a systematic review and meta-analysis.
Topics: Administration, Intravenous; Administration, Oral; Adult; Antihypertensive Agents; Cost-Benefit Anal | 2016 |
A review of oral labetalol and nifedipine in mild to moderate hypertension in pregnancy.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension, | 2015 |
Hypertensive Emergencies in Pregnancy.
Topics: Antihypertensive Agents; Cesarean Section; Chronic Disease; Congenital Abnormalities; Emergencies; E | 2016 |
The safety of tocolytics used for the inhibition of preterm labour.
Topics: Animals; Female; Humans; Infant, Newborn; Nifedipine; Obstetric Labor, Premature; Pregnancy; Prematu | 2016 |
Progesterone and nifedipine for maintenance tocolysis after arrested preterm labor: A systematic review and meta-analysis of randomized controlled trial.
Topics: Drug Therapy, Combination; Female; Humans; Maintenance Chemotherapy; Nifedipine; Obstetric Labor, Pr | 2016 |
Nifedipine maintenance tocolysis and perinatal outcome: an individual participant data meta-analysis.
Topics: Adult; Female; Gestational Age; Humans; Infant, Newborn; Infant, Newborn, Diseases; Nifedipine; Peri | 2016 |
Pharmacotherapeutic options for the treatment of preeclampsia.
Topics: Female; Humans; Hydralazine; Magnesium Sulfate; Nicardipine; Nifedipine; Nitroprusside; Pre-Eclampsi | 2009 |
Prematurity prevention: the role of acute tocolysis.
Topics: Acute Disease; Administration, Oral; Calcium Channel Blockers; Clinical Trials as Topic; Female; Hum | 2009 |
[Tocolytic therapy in threatened preterm labor].
Topics: Calcium Channel Blockers; Cyclooxygenase Inhibitors; Female; Humans; Magnesium Sulfate; Nifedipine; | 2010 |
Calcium channel blockers for the management of preterm birth: a review.
Topics: Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Premature; Practice Patterns, | 2011 |
Magnesium sulphate versus phenytoin for eclampsia.
Topics: Anticonvulsants; Clonazepam; Diazepam; Drug Combinations; Eclampsia; Female; Humans; Magnesium Sulfa | 2010 |
Effectiveness of nifedipine tocolysis to facilitate external cephalic version: a systematic review.
Topics: Breech Presentation; Female; Humans; Nifedipine; Pregnancy; Pregnancy Outcome; Randomized Controlled | 2011 |
Nifedipine in the management of preterm labor: a systematic review and metaanalysis.
Topics: Adrenergic beta-2 Receptor Agonists; Female; Humans; Magnesium Sulfate; Nifedipine; Obstetric Labor, | 2011 |
Tocolytics for preterm premature rupture of membranes.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Anti-Bacterial Agents; Female; Fetal Membranes, P | 2011 |
Tocolytic therapy for acute preterm labor.
Topics: Calcium Channel Blockers; Drug Administration Schedule; Female; Gestational Age; Humans; Indomethaci | 2012 |
Tocolytic therapy for acute preterm labor.
Topics: Calcium Channel Blockers; Drug Administration Schedule; Female; Gestational Age; Humans; Indomethaci | 2012 |
Tocolytic therapy for acute preterm labor.
Topics: Calcium Channel Blockers; Drug Administration Schedule; Female; Gestational Age; Humans; Indomethaci | 2012 |
Tocolytic therapy for acute preterm labor.
Topics: Calcium Channel Blockers; Drug Administration Schedule; Female; Gestational Age; Humans; Indomethaci | 2012 |
[Clinical efficacy and perinatal outcome of nifedipine for severe preeclampsia: meta-analysis].
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Infant, Newborn; | 2012 |
[Nifedipine first choice in management of threatening preterm labor].
Topics: Administration, Oral; Adrenergic beta-Agonists; Calcium Channel Blockers; Female; Humans; Infant Mor | 2002 |
[Which tocolytic drugs in case of preterm labor?].
Topics: Clinical Trials as Topic; Female; France; Humans; Nifedipine; Obstetric Labor, Premature; Practice G | 2002 |
[Special management for threatened preterm delivery in multiple pregnancies].
Topics: Adrenal Cortex Hormones; Drug Therapy, Combination; Female; France; Humans; Infant, Newborn; Nifedip | 2002 |
Effectiveness of nifedipine versus atosiban for tocolysis in preterm labour: a meta-analysis with an indirect comparison of randomised trials.
Topics: Adrenergic beta-Agonists; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Randomi | 2003 |
Calcium channel blockers for inhibiting preterm labour; a systematic review of the evidence and a protocol for administration of nifedipine.
Topics: Calcium Channel Blockers; Clinical Protocols; Contraindications; Female; Humans; Nifedipine; Obstetr | 2003 |
Maintenance therapy with calcium channel blockers for preventing preterm birth after threatened preterm labour.
Topics: Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Prematu | 2004 |
Symptomatic hypocalcemia after tocolytic therapy with magnesium sulfate and nifedipine.
Topics: Adult; Calcium Gluconate; Female; Gestational Age; Humans; Hypocalcemia; Magnesium Sulfate; Maternal | 2004 |
Pharmacokinetics of tocolytic agents.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic | 2004 |
Use of calcium channel antagonists for preterm labor.
Topics: Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy | 2005 |
The quality of nifedipine studies used to assess tocolytic efficacy: a systematic review.
Topics: Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Publications; Randomized Controll | 2005 |
Calcium channel blockers for tocolysis: a review of their role and safety following reports of serious adverse events.
Topics: Adrenergic beta-Agonists; Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Pre | 2006 |
Pathophysiology and medical management of systemic hypertension in preeclampsia.
Topics: Adrenergic beta-Antagonists; Aspirin; Calcium; Calcium Channel Blockers; Cerebral Hemorrhage; Female | 2006 |
A quality assessment tool to evaluate tocolytic studies.
Topics: Adrenergic beta-Agonists; Calcium Channel Blockers; Clinical Trials as Topic; Female; Humans; Meta-A | 2006 |
Emerging tocolytics for maintenance therapy of preterm labour: oxytocin antagonists and calcium channel blockers.
Topics: Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Premature; Oxytocin; Pregnanc | 2006 |
Preterm labour. The present and future of tocolysis.
Topics: Adrenergic beta-Agonists; Female; Humans; Indomethacin; Magnesium Sulfate; Nifedipine; Obstetric Lab | 2007 |
The choice of a tocolytic for the treatment of preterm labor: a critical evaluation of nifedipine versus atosiban.
Topics: Adrenergic beta-Agonists; Antidiuretic Hormone Receptor Antagonists; Calcium Channel Blockers; Femal | 2007 |
Developments in the pharmacotherapeutic management of spontaneous preterm labor.
Topics: Female; Fetus; Glucocorticoids; Health Care Costs; Humans; Magnesium Sulfate; Nifedipine; Obstetric | 2008 |
Possible treatment of pre-eclampsia with calcium channel blocking agents.
Topics: Calcium Channel Blockers; Eclampsia; Female; Fetus; Humans; Hypertension; Nifedipine; Placenta; Pre- | 1983 |
Hypertensive crisis.
Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia | 1984 |
Microcirculatory actions and uses of naturally-occurring (magnesium) and novel synthetic calcium channel blockers.
Topics: Anesthesia; Animals; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Cell Membrane Pe | 1984 |
[Indications for use of calcium antagonists].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Cardiotonic Agents; Coronary Disease | 1980 |
Inhibition of myometrial activity by calcium antagonists.
Topics: Abortion, Missed; Calcium Channel Blockers; Female; Humans; In Vitro Techniques; Nifedipine; Obstetr | 1981 |
Use of nifedipine in the hypertensive diseases of pregnancy.
Topics: Female; Humans; Hydralazine; Hypertension; Nifedipine; Pre-Eclampsia; Pregnancy; Pregnancy Complicat | 1994 |
[Nifedipine as a tocolytic drug].
Topics: Animals; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Tocolysis | 1994 |
Antihypertensive drugs of choice for treating preeclampsia.
Topics: Antihypertensive Agents; Female; Fetal Distress; Humans; Labetalol; Nifedipine; Pre-Eclampsia; Pregn | 1994 |
Nifedipine and its indications in obstetrics and gynecology.
Topics: Animals; Female; Fetus; Humans; Hypertension; Nifedipine; Pregnancy; Pregnancy Complications, Cardio | 1994 |
Calcium channel blockers.
Topics: Animals; Calcium Channel Blockers; Clinical Trials as Topic; Female; Humans; Nifedipine; Obstetric L | 1995 |
Acute pseudo-obstruction of the colon (Ogilvie's syndrome) resulting from combination tocolytic therapy.
Topics: Acute Disease; Adult; Colonic Pseudo-Obstruction; Female; Humans; Magnesium; Nifedipine; Pregnancy; | 1996 |
Analysis of the risks associated with calcium channel blockade: implications for the obstetrician-gynecologist.
Topics: Calcium Channel Blockers; Drug Interactions; Female; Gastrointestinal Hemorrhage; Heart Diseases; Hu | 1997 |
Magnesium sulphate: a review of clinical pharmacology applied to obstetrics.
Topics: Anesthesia, Obstetrical; Anticonvulsants; Breast Feeding; Calcium Channel Blockers; Cerebrovascular | 1998 |
Management of acute severe hypertension and encephalopathy.
Topics: Acute Disease; Antihypertensive Agents; Brain Diseases; Female; Humans; Hypertension; Nifedipine; Ni | 1999 |
Nifedipine versus ritodrine for suppression of preterm labor; a meta-analysis.
Topics: Female; Humans; Infant Mortality; Infant, Newborn; Nifedipine; Obstetric Labor, Premature; Odds Rati | 1999 |
The diagnosis and management of hypertensive crises.
Topics: Antihypertensive Agents; Aortic Aneurysm; Aortic Dissection; Clonidine; Diazoxide; Enalaprilat; Fema | 2000 |
Tocolysis with nifedipine or beta-adrenergic agonists: a meta-analysis.
Topics: Adrenergic beta-Agonists; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Randomi | 2001 |
[Tocolysis with calcium-channel-blockers].
Topics: Adrenergic beta-Agonists; Animals; Calcium Channel Blockers; Female; Humans; MEDLINE; Nifedipine; Pr | 2001 |
Calcium channel blockers in the management of preterm labor and hypertension in pregnancy.
Topics: Breast Feeding; Calcium Channel Blockers; Female; Humans; Hypertension; Maternal-Fetal Exchange; Nif | 2001 |
Calcium channel blockers as tocolytics.
Topics: Animals; Calcium Channel Blockers; Female; Humans; MEDLINE; Nifedipine; Obstetric Labor, Premature; | 2001 |
Preterm labour.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cerclage, Cervical; Ce | 2002 |
Fast Na+ channels and slow Ca2+ current in smooth muscle from pregnant rat uterus.
Topics: Adenosine; Animals; Calcium Channels; Female; Ion Channel Gating; Ion Channels; Isoproterenol; Magne | 1992 |
[Nifedipine in gynecology and obstetrics].
Topics: Amenorrhea; Antihypertensive Agents; Female; Fetus; Humans; Hypertension; Nifedipine; Obstetric Labo | 1992 |
Doppler flow velocimetry in hypertension in pregnancy.
Topics: Female; Fetus; Hemodynamics; Humans; Hypertension; Labetalol; Mass Screening; Nifedipine; Placenta; | 1991 |
[Calcium antagonists: accounts on new perspectives of their use and an update on side effects].
Topics: Adult; Animals; Asthma; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Esophageal Ach | 1989 |
Antihypertensive drugs in pregnancy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diazoxide; Diuretics; Female; Fetus; Humans; H | 1985 |
[Gingival hypertrophy].
Topics: Ascorbic Acid Deficiency; Cyclosporins; Female; Gingival Hypertrophy; Gingival Neoplasms; Hamartoma | 1988 |
Hypertensive cardiovascular emergencies.
Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia | 1985 |
154 trials available for nifedipine and Pregnancy
| Article | Year |
|---|---|
Tocolysis in the management of preterm prelabor rupture of membranes at 22-33 weeks of gestation: study protocol for a multicenter, double-blind, randomized controlled trial comparing nifedipine with placebo (TOCOPROM).
Topics: Administration, Oral; Double-Blind Method; Female; Fetal Membranes, Premature Rupture; Gestational A | 2021 |
Trial of Intrapartum Extended-Release Nifedipine to Prevent Severe Hypertension Among Pregnant Individuals With Preeclampsia With Severe Features.
Topics: Blood Pressure; Female; Humans; Hypertension; Infant, Newborn; Nifedipine; Pre-Eclampsia; Pregnancy | 2023 |
Effects of Nifedipine and Labetalol Combined with Magnesium Sulfate on Blood Pressure Control, Blood Coagulation Function, and Maternal and Infant Outcome in Patients with Pregnancy-Induced Hypertension.
Topics: Antihypertensive Agents; Blood Coagulation; Blood Pressure; Female; Humans; Hypertension; Hypertensi | 2022 |
Oral combined hydrochlorothiazide and lisinopril vs nifedipine for postpartum hypertension: a comparative-effectiveness pilot randomized controlled trial.
Topics: Antihypertensive Agents; Bayes Theorem; Blood Pressure; Double-Blind Method; Female; Humans; Hydroch | 2023 |
Efficacy of Oral Nifedipine, Naproxen, or Placebo for Pain Relief During Diagnostic Hysteroscopy in an Office Setting: A Randomized Pilot Study.
Topics: Double-Blind Method; Female; Humans; Hysteroscopy; Naproxen; Nifedipine; Pain; Pilot Projects; Pregn | 2023 |
Effectiveness of nifedipine, labetalol, and hydralazine as emergency antihypertension in severe preeclampsia: a randomized control trial.
Topics: Antihypertensive Agents; Female; Humans; Hydralazine; Labetalol; Nifedipine; Pre-Eclampsia; Pregnanc | 2022 |
Assessing the efficacy and safety of Sildenafil
Topics: Abortion, Habitual; Female; Humans; Nifedipine; Pregnancy; Pregnancy Trimester, First; Sildenafil Ci | 2023 |
A treatment strategy with nifedipine versus labetalol for women with pregnancy hypertension: study protocol for a randomised controlled trial (Giant PANDA).
Topics: Animals; Antihypertensive Agents; Female; Humans; Hypertension; Infant; Infant, Newborn; Labetalol; | 2023 |
A randomized controlled trial comparing the efficacy of nifedipine and enalapril in the postpartum period.
Topics: Antihypertensive Agents; Enalapril; Female; Humans; Hypertension; Nifedipine; Postpartum Period; Pre | 2023 |
Quantifying adherence to antihypertensive medication for chronic hypertension during pregnancy.
Topics: Adult; Antihypertensive Agents; Blood Pressure Determination; Chromatography, High Pressure Liquid; | 2019 |
Methyldopa versus nifedipine or no medication for treatment of chronic hypertension during pregnancy: A multicenter randomized clinical trial.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Egypt; Female; Humans; Hypertension; Hypertens | 2019 |
Effectiveness of an oral versus sublingual loading dose of nifedipine for tocolysis.
Topics: Administration, Oral; Administration, Sublingual; Adult; Brazil; Female; Gestational Age; Humans; Ni | 2020 |
Effects of tocolysis with nifedipine or atosiban on child outcome: follow-up of the APOSTEL III trial.
Topics: Child Behavior Disorders; Child, Preschool; Executive Function; Female; Follow-Up Studies; Health St | 2020 |
Intravenous labetalol versus oral nifedipine for acute hypertension in pregnancy: effects on cerebral perfusion pressure.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Cerebrovascular Circulation; Cohort Studies; F | 2020 |
To study the changes in maternal hemodynamics with intravenous labetalol or nifedipine in acute severe hypertension.
Topics: Administration, Intravenous; Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; F | 2020 |
The effectiveness of nifedipine/indomethacin combination therapy and nifedipine monotherapy for postponing preterm birth (25-34 weeks of gestation) in Sudanese women: a randomized clinical trial study protocol.
Topics: Adolescent; Adult; Combined Modality Therapy; Female; Gestational Age; Humans; Indomethacin; Infant, | 2021 |
Nifedipine for Acute Tocolysis of Preterm Labor: A Placebo-Controlled Randomized Trial.
Topics: Adult; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Tocolytic Agents; Young Ad | 2021 |
Maintenance nifedipine therapy for preterm symptomatic placenta previa: A randomized, multicenter, double-blind, placebo-controlled trial.
Topics: Adult; Double-Blind Method; Female; Gestational Age; Humans; Nifedipine; Placenta Previa; Pregnancy; | 2017 |
Effect of nifedipine and atosiban on perinatal brain injury: secondary analysis of the APOSTEL-III trial.
Topics: Administration, Intravenous; Adult; Brain Injuries; Female; Gestational Age; Humans; Infant, Newborn | 2018 |
Epigallocatechin gallate enhances treatment efficacy of oral nifedipine against pregnancy-induced severe pre-eclampsia: A double-blind, randomized and placebo-controlled clinical study.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; Catechin; Double-Blind Method; | 2018 |
Celastrol synergizes with oral nifedipine to attenuate hypertension in preeclampsia: a randomized, placebo-controlled, and double blinded trial.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug | 2017 |
Effect of maintenance tocolysis with nifedipine in established preterm labour on pregnancy prolongation and neonatal outcome.
Topics: Administration, Oral; Adult; Apgar Score; Birth Weight; Female; Gestational Age; Humans; India; Infa | 2018 |
Hydralazine vs nifedipine for acute hypertensive emergency in pregnancy: a randomized controlled trial.
Topics: Acute Disease; Adolescent; Adult; Apgar Score; Double-Blind Method; Emergencies; Female; Humans; Hyd | 2017 |
Lipid profile and cytokines in hypertension of pregnancy: A comparison of preeclampsia therapies.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cytokines; Double-Blind Method; Drug Administration | 2018 |
Longitudinal changes in vascular function parameters in pregnant women with chronic hypertension and association with adverse outcome: a cohort study.
Topics: Adult; Antihypertensive Agents; Birth Weight; Black People; Blood Pressure; Chronic Disease; Cohort | 2019 |
A double-blinded, randomized, placebo-controlled trial assessing the effects of nifedipine on embryo transfer: Study protocol.
Topics: Chi-Square Distribution; Double-Blind Method; Embryo Transfer; Female; Fertilization in Vitro; Human | 2017 |
Implementation of a standardized nurse initiated protocol to manage severe hypertension in pregnancy.
Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure Determination; Clinical Protocols; Dru | 2020 |
Nifedipine alone or combined with sildenafil citrate for management of threatened preterm labour: a randomised trial.
Topics: Administration, Intravaginal; Administration, Oral; Adult; Drug Monitoring; Drug Synergism; Female; | 2019 |
Cost effectiveness of nifedipine compared with atosiban in the treatment of threatened preterm birth (APOSTEL III trial).
Topics: Cost-Benefit Analysis; Female; Humans; Nifedipine; Pregnancy; Pregnancy, Multiple; Premature Birth; | 2019 |
Does nifedipine improve outcomes of embryo transfer?: Interim analysis of a randomized, double blinded, placebo-controlled trial.
Topics: Adult; Calcium Channel Blockers; Double-Blind Method; Embryo Implantation; Embryo Transfer; Female; | 2019 |
A comparative study on the efficacy of nifedipine and indomethacin for prevention of preterm birth as monotherapy and combination therapy: a randomized clinical trial.
Topics: Female; Humans; Indomethacin; Infant; Infant, Newborn; Nifedipine; Obstetric Labor, Premature; Pregn | 2020 |
To study the changes in fetal hemodynamics with intravenous labetalol or nifedipine in acute severe hypertension.
Topics: Administration, Intravenous; Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; F | 2019 |
IV labetalol and oral nifedipine in acute control of severe hypertension in pregnancy-A randomized controlled trial.
Topics: Administration, Intravenous; Administration, Oral; Antihypertensive Agents; Double-Blind Method; Fem | 2019 |
Formulation, Optimization, and In vivo Evaluation of Gastroretentive Drug Delivery System of Nifedipine for the Treatment of Preeclampsia.
Topics: Adult; Biological Availability; Chemistry, Pharmaceutical; Cross-Over Studies; Delayed-Action Prepar | 2019 |
Phytosterol enhances oral nifedipine treatment in pregnancy-induced preeclampsia: A placebo-controlled, double-blinded, randomized clinical trial.
Topics: Administration, Oral; Adult; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; | 2019 |
Oral antihypertensive regimens (nifedipine retard, labetalol, and methyldopa) for management of severe hypertension in pregnancy: an open-label, randomised controlled trial.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension, | 2019 |
A comparison of three tocolytics for preterm labor: a randomized clinical trial.
Topics: Adolescent; Adult; Drug Administration Routes; Female; Gestational Age; Humans; Indomethacin; Magnes | 2014 |
Oral nifedipine or intravenous labetalol for hypertensive emergency in pregnancy: a randomized controlled trial.
Topics: Administration, Intravenous; Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; D | 2013 |
48-hours administration of nifedipine in spontaneous preterm labor - Doppler blood flow assessment of placental and fetal circulation.
Topics: Adult; Dose-Response Relationship, Drug; Female; Fetus; Hemodynamics; Humans; Middle Cerebral Artery | 2013 |
Comparison of nifedipine and progesterone for maintenance tocolysis after arrested preterm labour.
Topics: Adult; Female; Humans; Maintenance Chemotherapy; Nifedipine; Obstetric Labor, Premature; Pregnancy; | 2014 |
The NIFTY study: a multicentre randomised double-blind placebo-controlled trial of nifedipine maintenance tocolysis in fetal fibronectin-positive women in threatened preterm labour.
Topics: Adult; Double-Blind Method; Female; Fibronectins; Gestational Age; Humans; Infant, Newborn; Kaplan-M | 2014 |
Nifedipine versus atosiban in the treatment of threatened preterm labour (Assessment of Perinatal Outcome after Specific Tocolysis in Early Labour: APOSTEL III-Trial).
Topics: Administration, Oral; Adolescent; Adult; Dose-Response Relationship, Drug; Female; Follow-Up Studies | 2014 |
Prophylactic oral nifedipine to reduce preterm delivery: a randomized controlled trial in women at high risk.
Topics: Administration, Oral; Adult; Asymptomatic Diseases; Cervical Length Measurement; Double-Blind Method | 2014 |
Comparison between nitroglycerin dermal patch and nifedipine for treatment of preterm labor: a randomized clinical trial.
Topics: Apgar Score; Birth Weight; Cesarean Section; Female; Gestational Age; Humans; Infant, Newborn; Inten | 2014 |
Nifedipine versus terbutaline, tocolytic effectiveness and maternal and neonatal adverse effects: a randomized, controlled pilot trial.
Topics: Adult; Female; Follow-Up Studies; Humans; Infant, Newborn; Nifedipine; Obstetric Labor, Premature; P | 2015 |
Single versus combination tocolytic regimen in the prevention of preterm births in women: a prospective cohort study.
Topics: Albuterol; Drug Therapy, Combination; Female; Humans; Nifedipine; Pregnancy; Premature Birth; Prospe | 2015 |
Pharmacokinetics of nifedipine slow-release during sustained tocolysis.
Topics: Adult; Bayes Theorem; Biological Availability; Body Weight; Chemistry, Pharmaceutical; Delayed-Actio | 2015 |
Randomized comparison of nifedipine and placebo in fibronectin-negative women with symptoms of preterm labor and a short cervix (APOSTEL-I Trial).
Topics: Adult; Cervical Length Measurement; Female; Fibronectins; Gestational Age; Humans; Netherlands; Nife | 2015 |
Impact of a randomized trial on maintenance tocolysis on length of hospital admission of women with threatened preterm labor in The Netherlands.
Topics: Female; Gestational Age; Humans; Length of Stay; Netherlands; Nifedipine; Obstetric Labor, Premature | 2015 |
Tocolysis in women with advanced preterm labor: a secondary analysis of a randomized clinical trial.
Topics: Administration, Intravenous; Administration, Oral; Administration, Rectal; Adolescent; Adult; Female | 2016 |
Fetal fibronectin status and cervical length in women with threatened preterm labor and the effectiveness of maintenance tocolysis.
Topics: Adult; Cervical Length Measurement; Female; Fibronectins; Humans; Nifedipine; Obstetric Labor, Prema | 2016 |
Maintenance tocolysis with nifedipine in threatened preterm labour: 2-year follow up of the offspring in the APOSTEL II trial.
Topics: Adult; Analysis of Variance; Double-Blind Method; Female; Fetal Membranes, Premature Rupture; Follow | 2016 |
RETRACTED: Nicorandil vs nifedipine for the treatment of preterm labour: a randomized clinical trial.
Topics: Adolescent; Adult; Double-Blind Method; Female; Fetal Diseases; Headache; Humans; Nicorandil; Nifedi | 2015 |
Nifedipine versus atosiban for threatened preterm birth (APOSTEL III): a multicentre, randomised controlled trial.
Topics: Administration, Intravenous; Administration, Ophthalmic; Adult; Belgium; Calcium Channel Blockers; F | 2016 |
Nifedipine versus placebo in the treatment of preterm prelabor rupture of membranes: a randomized controlled trial: Assessment of perinatal outcome by use of tocolysis in early labor-APOSTEL IV trial.
Topics: Adult; Female; Fetal Membranes, Premature Rupture; Humans; Nifedipine; Obstetric Labor, Premature; P | 2016 |
Oral nifedipine vs. intravenous labetalol for treatment of pregnancy-induced severe pre-eclampsia.
Topics: Administration, Intravenous; Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; D | 2016 |
Furosemide in postpartum management of severe preeclampsia: A randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Female; Furosemide; Humans; Ni | 2017 |
Furosemide in postpartum management of severe preeclampsia: A randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Female; Furosemide; Humans; Ni | 2017 |
Furosemide in postpartum management of severe preeclampsia: A randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Female; Furosemide; Humans; Ni | 2017 |
Furosemide in postpartum management of severe preeclampsia: A randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Female; Furosemide; Humans; Ni | 2017 |
Nifedipine versus terbutaline for tocolysis in external cephalic version.
Topics: Adult; Breech Presentation; Female; Humans; Nifedipine; Pregnancy; Terbutaline; Term Birth; Tocolyti | 2008 |
Nifedipine as a uterine relaxant for external cephalic version: a randomized controlled trial.
Topics: Adult; Breech Presentation; Cesarean Section; Female; Humans; Nifedipine; Pregnancy; Tocolytic Agent | 2008 |
Maintenance nifedipine tocolysis compared with placebo: a randomized controlled trial.
Topics: Adult; Drug Administration Schedule; Female; Humans; Kaplan-Meier Estimate; Nifedipine; Obstetric La | 2008 |
Maintenance nifedipine tocolysis compared with placebo: a randomized controlled trial.
Topics: Adult; Drug Administration Schedule; Female; Humans; Kaplan-Meier Estimate; Nifedipine; Obstetric La | 2008 |
Maintenance nifedipine tocolysis compared with placebo: a randomized controlled trial.
Topics: Adult; Drug Administration Schedule; Female; Humans; Kaplan-Meier Estimate; Nifedipine; Obstetric La | 2008 |
Maintenance nifedipine tocolysis compared with placebo: a randomized controlled trial.
Topics: Adult; Drug Administration Schedule; Female; Humans; Kaplan-Meier Estimate; Nifedipine; Obstetric La | 2008 |
Oral nifepidine versus subcutaneous terbutaline tocolysis for external cephalic version: a double-blind randomised trial.
Topics: Administration, Oral; Adult; Breech Presentation; Cesarean Section; Chemotherapy, Adjuvant; Double-B | 2009 |
Two dose regimens of nifedipine for management of preterm labor: a randomized controlled trial.
Topics: Adult; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Tocolytic Agents; Uterine | 2009 |
The effects of the tocolytics atosiban and nifedipine on fetal movements, heart rate and blood flow.
Topics: Adult; Algorithms; Betamethasone; Drug Combinations; Female; Fetal Blood; Fetal Movement; Heart Rate | 2009 |
[Treatment of albuminuria in gestational hypertension puerpera in the severe preeclampeia stage by TCM therapy for stasis-removing and diuresis].
Topics: Adult; Albuminuria; Diagnosis, Differential; Drug Therapy, Combination; Drugs, Chinese Herbal; Femal | 2009 |
Healthcare evaluation of the use of atosiban and fibronectin for the management of pre-term labour.
Topics: Decision Trees; Female; Fibronectins; Health Services Research; Humans; Nifedipine; Obstetric Labor, | 2009 |
Cost-effectiveness of fibronectin testing in a triage in women with threatened preterm labor: alleviation of pregnancy outcome by suspending tocolysis in early labor (APOSTEL-I trial).
Topics: Cervical Length Measurement; Cohort Studies; Cost-Benefit Analysis; Female; Fibronectins; Humans; La | 2009 |
Assessment of perinatal outcome after sustained tocolysis in early labour (APOSTEL-II trial).
Topics: Cervical Length Measurement; Clinical Protocols; Drug Administration Schedule; Female; Fibronectins; | 2009 |
An examination of the clinical benefits and cost-effectiveness of tocolytic replacement following recurrent preterm labor.
Topics: Adult; Cost-Benefit Analysis; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pre | 2010 |
[Transdermal nitroglycerin versus oral nifedipine administration for tocolysis: a randomized clinical trial].
Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Female; Humans; Nifedipine; Nitr | 2009 |
Comparison of success rate of nifedipine, progesterone, and bed rest for inhibiting uterine contraction in threatened preterm labor.
Topics: 17 alpha-Hydroxyprogesterone Caproate; Adolescent; Adult; Bed Rest; Delayed-Action Preparations; Fem | 2011 |
Comparison of the efficacy and adverse effects of nifedipine and indomethacin for the treatment of preterm labor.
Topics: Adult; Drug Administration Schedule; Female; Humans; Indomethacin; Nifedipine; Obstetric Labor, Prem | 2011 |
A pilot study of the impact of genotype on nifedipine pharmacokinetics when used as a tocolytic.
Topics: Adolescent; Adult; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Female; Genotype; Half- | 2012 |
Single dose 17 alpha-hydroxyprogesterone caproate in preterm labor: a randomized trial.
Topics: 17 alpha-Hydroxyprogesterone Caproate; Adrenal Cortex Hormones; Adult; Double-Blind Method; Drug The | 2012 |
Oral nifedipine versus intravenous labetalol for acute blood pressure control in hypertensive emergencies of pregnancy: a randomised trial.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Emergenci | 2012 |
Comparison of the efficacy of nifedipine and hydralazine in hypertensive crisis in pregnancy.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; H | 2011 |
Management of eclampsia at Assiut University Hospital, Egypt.
Topics: Adolescent; Adult; Anticonvulsants; Antihypertensive Agents; Clinical Protocols; Combined Modality T | 2012 |
Medical treatment of early-onset mild gestational hypertension reduces total peripheral vascular resistance and influences maternal and fetal complications.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Echocardiography; Female; Humans; Hypertension, Preg | 2012 |
The tocolytic role of nifedipine in preventing preterm labour pain.
Topics: Adult; Analgesia, Obstetrical; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; To | 2012 |
Nifedipine versus fenoterol in the management of preterm labor: a randomized, multicenter clinical study.
Topics: Adolescent; Adult; Costs and Cost Analysis; Female; Fenoterol; Humans; Nifedipine; Obstetric Labor, | 2012 |
Effect of antenatal tocolysis on neonatal outcomes.
Topics: Female; Gestational Age; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Magnesium | 2012 |
Effect of cervical length to the efficacy of nifedipine and bed rest for inhibiting threatened preterm labor.
Topics: Bed Rest; Cervix Uteri; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Tocolytic | 2012 |
Nifedipine compared with atosiban for treating preterm labor: a randomized controlled trial.
Topics: Adult; Cross-Over Studies; Female; Gestational Age; Humans; Infant, Newborn; Middle Aged; Nifedipine | 2012 |
Effect of maintenance tocolysis with nifedipine in threatened preterm labor on perinatal outcomes: a randomized controlled trial.
Topics: Adult; Double-Blind Method; Drug Administration Schedule; Enterocolitis, Necrotizing; Female; Fetal | 2013 |
Does nifedipine prevent the tachysystole associated with misoprostol induction?
Topics: Administration, Intravaginal; Administration, Oral; Female; Humans; Labor, Induced; Misoprostol; Nif | 2002 |
Efficacy and safety of nifedipine tablets for the acute treatment of severe hypertension in pregnancy.
Topics: Acute Disease; Blood Pressure; Capsules; Female; Humans; Hypertension; Nifedipine; Pregnancy; Pregna | 2002 |
A comparison of magnesium sulfate and nimodipine for the prevention of eclampsia.
Topics: Anticonvulsants; Calcium Channel Blockers; Eclampsia; Female; Humans; Logistic Models; Magnesium Sul | 2003 |
A comparison of magnesium sulfate and nimodipine for the prevention of eclampsia.
Topics: Anticonvulsants; Calcium Channel Blockers; Eclampsia; Female; Humans; Logistic Models; Magnesium Sul | 2003 |
A comparison of magnesium sulfate and nimodipine for the prevention of eclampsia.
Topics: Anticonvulsants; Calcium Channel Blockers; Eclampsia; Female; Humans; Logistic Models; Magnesium Sul | 2003 |
A comparison of magnesium sulfate and nimodipine for the prevention of eclampsia.
Topics: Anticonvulsants; Calcium Channel Blockers; Eclampsia; Female; Humans; Logistic Models; Magnesium Sul | 2003 |
A comparison of magnesium sulfate and nimodipine for the prevention of eclampsia.
Topics: Anticonvulsants; Calcium Channel Blockers; Eclampsia; Female; Humans; Logistic Models; Magnesium Sul | 2003 |
A comparison of magnesium sulfate and nimodipine for the prevention of eclampsia.
Topics: Anticonvulsants; Calcium Channel Blockers; Eclampsia; Female; Humans; Logistic Models; Magnesium Sul | 2003 |
A comparison of magnesium sulfate and nimodipine for the prevention of eclampsia.
Topics: Anticonvulsants; Calcium Channel Blockers; Eclampsia; Female; Humans; Logistic Models; Magnesium Sul | 2003 |
A comparison of magnesium sulfate and nimodipine for the prevention of eclampsia.
Topics: Anticonvulsants; Calcium Channel Blockers; Eclampsia; Female; Humans; Logistic Models; Magnesium Sul | 2003 |
A comparison of magnesium sulfate and nimodipine for the prevention of eclampsia.
Topics: Anticonvulsants; Calcium Channel Blockers; Eclampsia; Female; Humans; Logistic Models; Magnesium Sul | 2003 |
[Clinical observations on the prevention and treatment of premature labor with nifedipine].
Topics: Adult; Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; | 2002 |
Hemodynamic and metabolic effects after nifedipine and ritodrine tocolysis.
Topics: Adult; Cohort Studies; Female; Glucose; Hemodynamics; Humans; Metabolism; Nifedipine; Obstetric Labo | 2003 |
Oral nifedipine maintenance therapy after acute intravenous tocolysis in preterm labor.
Topics: Administration, Oral; Adolescent; Adult; Drug Administration Schedule; Female; Gestational Age; Huma | 2004 |
Acute efficacy of a sublingual dose of nifedipine on uterine arterial blood flow: preliminary data in prematurely menopausal women.
Topics: Administration, Sublingual; Analysis of Variance; Arteries; Calcium Channel Blockers; Female; Humans | 2004 |
Atosiban and nifedipin for the treatment of preterm labor.
Topics: Female; Humans; Nifedipine; Obstetric Labor, Premature; Oxytocics; Pregnancy; Tocolytic Agents; Vaso | 2005 |
[Efficacy of antihypertensive drugs in pregnancy].
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Delayed-Action Preparations; Female; Hemod | 2005 |
Nifedipine versus ritodrine for suppression of preterm labor. Comparison of their efficacy and secondary effects.
Topics: Administration, Oral; Adult; Female; Gestational Age; Humans; Infusions, Intravenous; Nifedipine; Ob | 2006 |
Long-term follow up of children exposed in utero to nifedipine or ritodrine for the management of preterm labour.
Topics: Adult; Affective Symptoms; Child; Child Behavior Disorders; Female; Follow-Up Studies; Gestational A | 2006 |
Tocolysis in women with preterm labor between 32 0/7 and 34 6/7 weeks of gestation: a randomized controlled pilot study.
Topics: Adult; Female; Humans; Infant, Newborn; Infant, Premature; Length of Stay; Magnesium Sulfate; Nifedi | 2006 |
Calcium and conjugated linoleic acid reduces pregnancy-induced hypertension and decreases intracellular calcium in lymphocytes.
Topics: Administration, Oral; Adolescent; Adult; Angiotensin II; Blood Pressure; Calcium; Calcium Channel Bl | 2006 |
Tocolytic efficacy of nifedipine versus ritodrine in preterm labor.
Topics: Apgar Score; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnancy Outcome; R | 2007 |
Psychological factors in preterm labor and psychotherapeutic intervention.
Topics: Female; Gestational Age; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Prospective Stud | 2007 |
Magnesium sulfate compared with nifedipine for acute tocolysis of preterm labor: a randomized controlled trial.
Topics: Administration, Oral; Adult; Female; Humans; Infusions, Intravenous; Magnesium Sulfate; Nifedipine; | 2007 |
Terbutaline versus nifedipine for prolongation of pregnancy in patients with preterm labor.
Topics: Administration, Oral; Adolescent; Adult; Female; Humans; Injections, Subcutaneous; Nifedipine; Obste | 2008 |
Magnesium sulfate compared with nifedipine for acute tocolysis of preterm labor: a randomized controlled trial.
Topics: Adult; Bias; Female; Humans; Magnesium Sulfate; Meta-Analysis as Topic; Nifedipine; Obstetric Labor, | 2007 |
Efficacy of nitroglycerine infusion versus sublingual nifedipine in severe pre-eclampsia: a randomized, triple-blind, controlled trial.
Topics: Administration, Sublingual; Adult; Female; Humans; Injections, Intravenous; Magnesium Sulfate; Nifed | 2008 |
Safety and efficacy of oral nifedipine versus terbutaline injection in preterm labor.
Topics: Administration, Oral; Adult; Blood Pressure; Female; Gestational Age; Humans; Injections, Intravenou | 2007 |
Tocolytic effectiveness of nifedipine versus ritodrine and follow-up of newborns: a randomised controlled trial.
Topics: Adrenergic beta-Agonists; Adult; Birth Weight; Calcium Channel Blockers; Child, Preschool; Female; F | 2008 |
Nifedipine gastrointestinal therapeutic system (GITS) as an alternative to slow-release for tocolysis--tolerance and pharmacokinetic profile.
Topics: Administration, Oral; Adult; Delayed-Action Preparations; Female; Humans; Nifedipine; Obstetric Labo | 2008 |
A comparison between the haemodynamic effects of oral nifedipine and intravenous dihydralazine in patients with severe pre-eclampsia.
Topics: Administration, Oral; Antihypertensive Agents; Calcium Channel Blockers; Dihydralazine; Female; Hemo | 1995 |
A comparison of nifedipine with methyldopa in pregnancy induced hypertension.
Topics: Adult; Female; Humans; Hypertension; Methyldopa; Nifedipine; Pregnancy; Pregnancy Complications, Car | 1994 |
[Nifedipine in preeclampsia for cesarean section].
Topics: Adult; Blood Pressure; Cesarean Section; Female; Humans; Nifedipine; Pre-Eclampsia; Pregnancy; Uteri | 1993 |
A safer and more effective treatment regimen for eclampsia.
Topics: Adult; Drug Synergism; Drug Therapy, Combination; Eclampsia; Female; Humans; Magnesium Sulfate; Nife | 1994 |
Evaluation of calcium-antagonist (Nifedipine) in the treatment of pre-eclampsia.
Topics: Adolescent; Adult; Female; Hemodynamics; Humans; Kidney Function Tests; Nifedipine; Pre-Eclampsia; P | 1993 |
Efficacy and safety of nifedipine versus magnesium sulfate in the management of preterm labor: a randomized study.
Topics: Administration, Oral; Administration, Sublingual; Adult; Chi-Square Distribution; Female; Humans; In | 1993 |
Nifedipine versus ritodrine for suppression of preterm labour.
Topics: Adult; Blood Pressure; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnancy | 1993 |
Clinical comparison of oral nifedipine and subcutaneous terbutaline for initial tocolysis.
Topics: Administration, Oral; Adult; Female; Humans; Infant, Newborn; Injections, Subcutaneous; Nifedipine; | 1993 |
[Management of severe pre-eclampsia/eclampsia. Comparison between nifedipine and hydralazine as antihypertensive agents].
Topics: Administration, Sublingual; Antihypertensive Agents; Apgar Score; Drug Evaluation; Eclampsia; Female | 1993 |
Nifedipine attenuates the hypertensive response to tracheal intubation in pregnancy-induced hypertension.
Topics: Administration, Sublingual; Adult; Anesthesia, Intravenous; Apgar Score; Blood Gas Analysis; Blood P | 1993 |
Sublingual nifedipine compared with intravenous hydrallazine in the acute treatment of severe hypertension in pregnancy: potential for use in rural practice.
Topics: Administration, Sublingual; Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hydra | 1996 |
Intraplatelet free calcium and calcium-regulating hormones in plasma are not related to the antihypertensive effect of nifedipine in hypertensive pregnancy.
Topics: Adult; Blood Platelets; Calcium; Calcium Channel Blockers; Contraceptive Agents; Female; Humans; Hyd | 1995 |
Nifedipine reduces thromboxane A2 production by platelets without changing aggregation in hypertensive pregnancy.
Topics: Adult; Antihypertensive Agents; Blood Platelets; Blood Pressure; Female; Humans; Hypertension; In Vi | 1996 |
Nifedipine and ritodrine in the management of preterm labor: a randomized multicenter trial.
Topics: Administration, Oral; Adult; Female; Fetal Membranes, Premature Rupture; Humans; Infusions, Intraven | 1997 |
The addition of a diuretic to anti-hypertensive therapy for early severe hypertension in pregnancy.
Topics: Adult; Amiloride; Antihypertensive Agents; Diuretics; Drug Combinations; Drug Therapy, Combination; | 1998 |
A randomized comparison of nifedipine and ritodrine for suppression of preterm labor.
Topics: Adult; Blood Glucose; Blood Pressure; Female; Gestational Age; Humans; Nifedipine; Obstetric Labor, | 1998 |
The effect of nifedipine on urinary excretion of calcium in preeclampsia.
Topics: Adolescent; Adult; Calcium; Calcium Channel Blockers; Female; Humans; Nifedipine; Pre-Eclampsia; Pre | 1997 |
A prospective, randomized trial of nifedipine vs. ritodrine in threatened preterm labor.
Topics: Abortion, Threatened; Adult; Apgar Score; Blood Glucose; Female; Fetus; Gestational Age; Hemodynamic | 1998 |
Nifedipine versus expectant management in mild to moderate hypertension in pregnancy. Gruppo di Studio Ipertensione in Gravidanza.
Topics: Adult; Birth Weight; Calcium Channel Blockers; Delayed-Action Preparations; Female; Gestational Age; | 1998 |
Oral nifedipine therapy in the management of severe preeclampsia.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Female; Humans; Hydralazine; Infusions, Intrav | 1995 |
24-hour ambulatory blood pressure monitoring: a comparison between transdermal glyceryl-trinitrate and oral nifedipine.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Analysis of Variance; Female; Humans; Hypert | 1999 |
Maintenance oral nifedipine for preterm labor: a randomized clinical trial.
Topics: Adult; Female; Gestational Age; Humans; Magnesium Sulfate; Nifedipine; Obstetric Labor, Premature; P | 1999 |
A randomized, double-blind trial of oral nifedipine and intravenous labetalol in hypertensive emergencies of pregnancy.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Blood Pressure; Calcium Channel Blockers; | 1999 |
A randomized, double-blind, hemodynamic evaluation of nifedipine and labetalol in preeclamptic hypertensive emergencies.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; E | 1999 |
Prevention of preterm delivery: nifedipine or magnesium sulfate.
Topics: Administration, Oral; Female; Humans; Injections, Intravenous; Magnesium Sulfate; Nifedipine; Obstet | 1999 |
Neonatal effects of nifedipine and ritodrine for preterm labor.
Topics: Adult; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Nifedipine; Obstetric Labor | 2000 |
Nifedipine or prazosin as a second agent to control early severe hypertension in pregnancy: a randomised controlled trial.
Topics: Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hypertension; Ni | 2000 |
Nifedipine administered in pregnancy: effect on the development of children at 18 months.
Topics: Calcium Channel Blockers; Child Development; Female; Follow-Up Studies; Humans; Hypertension; Infant | 2000 |
[The effect of Nifedipine on postpartum blood loss in patients with pregnancy induced hypertension].
Topics: Calcium Channel Blockers; Female; Humans; Hypertension; Nifedipine; Postpartum Hemorrhage; Pregnancy | 2000 |
[Clinical observation on therapeutical effect of prepared rhubarb in treating pregnancy induced hypertension].
Topics: Adult; Antigen-Antibody Complex; CD4-CD8 Ratio; Drug Therapy, Combination; Female; Humans; Interleuk | 1999 |
Nifedipine versus terbutaline in management of preterm labor.
Topics: Adult; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnancy Outcome; Terbuta | 2002 |
Nifedipine or hydralazine as a first-line agent to control hypertension in severe preeclampsia.
Topics: Adolescent; Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Nifedipine; | 2002 |
Antihypertensive drug effects on placental flow velocity waveforms in pregnant women with severe hypertension.
Topics: Arteries; Blood Flow Velocity; Double-Blind Method; Female; Humans; Hydralazine; Hypertension; Nifed | 1992 |
A randomized prospective comparison of nifedipine and bed rest versus bed rest alone in the management of preeclampsia remote from term.
Topics: Bed Rest; Blood Pressure; Female; Humans; Nifedipine; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; P | 1992 |
[Treatment with calcium antagonist nifedipine in pathology of the preliminary period].
Topics: Adult; Female; Humans; Infant, Newborn; Nifedipine; Obstetric Labor, Premature; Pregnancy; Time Fact | 1992 |
[Management of severe pre-eclampsia in the puerperium. Comparative study of sublingual nifedipine and hydralazine].
Topics: Administration, Sublingual; Adolescent; Adult; Antihypertensive Agents; Female; Humans; Hydralazine; | 1991 |
Comparison of nifedipine and ritodrine for the treatment of preterm labor.
Topics: Adult; Birth Weight; Female; Fetus; Humans; Infant, Newborn; Infant, Newborn, Diseases; Nifedipine; | 1991 |
Effect of calcium channel blocker nifedipine on uterine artery flow velocity waveforms.
Topics: Arteries; Blood Flow Velocity; Blood Pressure; Female; Heart Rate; Humans; Nifedipine; Pregnancy; Ut | 1991 |
Nifedipine in the treatment of severe preeclampsia.
Topics: Adult; Blood Pressure; Female; Humans; Hydralazine; Nifedipine; Pre-Eclampsia; Pregnancy; Pregnancy | 1991 |
The effect of nifedipine on fetal umbilical artery Doppler waveforms in pregnancies complicated by hypertension.
Topics: Blood Flow Velocity; Blood Pressure; Double-Blind Method; Female; Heart Rate, Fetal; Humans; Hyperte | 1991 |
A comparison of tocolysis with nifedipine or ritodrine: analysis of efficacy and maternal, fetal, and neonatal outcome.
Topics: Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnancy Outcome; Prospective St | 1990 |
The use of nifedipine during the postpartum period in patients with severe preeclampsia.
Topics: Blood Pressure; Diuresis; Female; Humans; Nifedipine; Postpartum Period; Pre-Eclampsia; Pregnancy; R | 1990 |
Nifedipine versus ritodrine for suppressing preterm labor.
Topics: Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Prospective Studies; Ritodrine | 1990 |
[A randomized study of the treatment of threatened premature labor. Nifedipine versus ritodrine].
Topics: Adult; Apgar Score; Female; Heart Rate, Fetal; Humans; Infant, Newborn; Nifedipine; Obstetric Labor, | 1990 |
Nifedipine in acute hypertensive emergencies in pregnancy.
Topics: Acute Disease; Adolescent; Adult; Blood Pressure; Dihydralazine; Emergencies; Female; Humans; Hypert | 1989 |
Cardiovascular and metabolic effects associated with nifedipine and ritodrine tocolysis.
Topics: Blood Glucose; Blood Pressure; Chlorides; Drug Administration Schedule; Female; Hematocrit; Hemodyna | 1989 |
The effect of sublingual nifedipine on uteroplacental blood flow in hypertensive pregnancy.
Topics: Adult; Blood Flow Velocity; Blood Pressure; Female; Humans; Hypertension; Nifedipine; Placenta; Preg | 1988 |
Effects of nifedipine on umbilical artery velocity waveforms in healthy human fetuses.
Topics: Blood Flow Velocity; Clinical Trials as Topic; Double-Blind Method; Female; Fetus; Heart Rate, Fetal | 1987 |
The use of a calcium antagonist (nifedipine) to suppress preterm labour.
Topics: Administration, Oral; Adult; Clinical Trials as Topic; Female; Humans; Nifedipine; Obstetric Labor, | 1986 |
404 other studies available for nifedipine and Pregnancy
| Article | Year |
|---|---|
Which antihypertensive treatment is better for mild to moderate hypertension in pregnancy?
Topics: Antihypertensive Agents; Female; Humans; Hypertension, Pregnancy-Induced; Labetalol; Methyldopa; Nif | 2022 |
Maternal and neonatal outcomes of antihypertensive treatment in pregnancy: A retrospective cohort study.
Topics: Antihypertensive Agents; Birth Weight; Female; Humans; Hypertension, Pregnancy-Induced; Infant; Infa | 2022 |
Antihypertensive drug prescription trends for pregnant women with hypertension in acute hospitals in Japan.
Topics: Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Drug Prescriptions; Female; Hospitals | 2022 |
Assessing the Potency of the Novel Tocolytics 2-APB, Glycyl-H-1152, and HC-067047 in Pregnant Human Myometrium.
Topics: Aminophylline; Female; Humans; Indomethacin; Infant, Newborn; Myometrium; Nifedipine; Pregnancy; Pre | 2023 |
Fetal echocardiographic evaluation before and after nifedipine treatment in preterm labor.
Topics: Diastole; Echocardiography; Female; Fetal Heart; Humans; Infant, Newborn; Nifedipine; Obstetric Labo | 2022 |
Race/ethnicity differences in response to acute antihypertensive treatment of peripartum severe hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Ethnicity; Female; Humans; Hydralazine; Hypertension; Labet | 2022 |
Postpartum Readmission for Hypertension After Discharge on Labetalol or Nifedipine.
Topics: Antihypertensive Agents; Cohort Studies; Female; Humans; Hypertension; Hypertension, Pregnancy-Induc | 2022 |
Trends in antihypertensive prescription for pregnant women with hypertension and their peripartum outcomes before and after label and guideline revisions in Japan.
Topics: Antihypertensive Agents; Cesarean Section; Drug Prescriptions; Female; Humans; Hydralazine; Hyperten | 2022 |
Hypertensive Conditions: Hypertensive Disorders in Pregnancy.
Topics: Antihypertensive Agents; Female; Humans; Hypertension, Pregnancy-Induced; Labetalol; Nifedipine; Pre | 2022 |
Comparison of relaxant effects of nifedipine and NS11021 on isolated umbilical arteries of healthy and preeclamptic pregnant women.
Topics: Female; Humans; Nifedipine; Pre-Eclampsia; Pregnancy; Pregnant Women; Umbilical Arteries; Vasodilato | 2023 |
Comparison of relaxant effects of nifedipine and NS11021 on isolated umbilical arteries of healthy and preeclamptic pregnant women.
Topics: Female; Humans; Nifedipine; Pre-Eclampsia; Pregnancy; Pregnant Women; Umbilical Arteries; Vasodilato | 2023 |
Comparison of relaxant effects of nifedipine and NS11021 on isolated umbilical arteries of healthy and preeclamptic pregnant women.
Topics: Female; Humans; Nifedipine; Pre-Eclampsia; Pregnancy; Pregnant Women; Umbilical Arteries; Vasodilato | 2023 |
Comparison of relaxant effects of nifedipine and NS11021 on isolated umbilical arteries of healthy and preeclamptic pregnant women.
Topics: Female; Humans; Nifedipine; Pre-Eclampsia; Pregnancy; Pregnant Women; Umbilical Arteries; Vasodilato | 2023 |
Assessment of the tocolytic nifedipine in preclinical primary models of preterm birth.
Topics: Animals; Female; Humans; Infant, Newborn; Mice; Myometrium; Nifedipine; Obstetric Labor, Premature; | 2023 |
Sleep deprivation disturbs uterine contractility and structure in pregnant rats: role of matrix metalloproteinase 9 and transforming growth factor-β.
Topics: Acetylcholine; Animals; Biomarkers; Female; Matrix Metalloproteinase 9; Nifedipine; Oxytocin; Pregna | 2023 |
Comparison of outcomes following intravenous magnesium compared with intravenous labetalol and oral nifedipine in 355 pregnant Han Chinese women with preeclampsia.
Topics: Antihypertensive Agents; Blood Pressure; East Asian People; Female; Humans; Hypertension; Infant, Ne | 2023 |
Successful management of twin pregnancy in a woman with advanced chronic kidney disease: A case report.
Topics: Adult; Cesarean Section; China; Creatinine; Female; Glucocorticoids; Humans; Infant, Newborn; Nifedi | 2019 |
Role of Extracellular Calcium and Calcium Sensitization in the Anti-Contractile Effect of Perivascular Adipose Tissue in Pregnant Rat Aorta.
Topics: Adipose Tissue; Amides; Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Female; Indoles | 2019 |
Comparison of the efficacy of the immediate-release and osmotic push-pull system formulations of nifedipine for tocolysis.
Topics: Adult; Drug Compounding; Female; Humans; Infant, Newborn; Nifedipine; Pregnancy; Retrospective Studi | 2019 |
Nifedipine versus ritodrine during external cephalic version procedure: a case control study.
Topics: Breech Presentation; Case-Control Studies; Female; Humans; Israel; Nifedipine; Placenta; Pregnancy; | 2021 |
Nifedipine-Induced Shock in Pregnancy With Aortic Stenosis.
Topics: Aortic Valve Stenosis; Calcium Gluconate; Chest Pain; Electrocardiography; Female; Fetofetal Transfu | 2020 |
Bryophyllum pinnatum enhances the inhibitory effect of atosiban and nifedipine on human myometrial contractility: an in vitro study.
Topics: Adult; Drug Antagonism; Female; Humans; In Vitro Techniques; Kalanchoe; Myometrium; Nifedipine; Plan | 2019 |
Letter to the Editor regarding research integrity.
Topics: Antihypertensive Agents; Female; Humans; Hypertension; Methyldopa; Nifedipine; Pre-Eclampsia; Pregna | 2020 |
Effects of nifedipine and sildenafil on placental hemodynamics and gas exchange during fetal hypoxemia in a chronic sheep model.
Topics: Animals; Blood Pressure; Female; Hemodynamics; Hypoxia; Nifedipine; Placenta; Pregnancy; Sheep; Sild | 2020 |
Identification of factors associated with delayed treatment of obstetric hypertensive emergencies.
Topics: Administration, Intravenous; Administration, Oral; Adult; After-Hours Care; Antihypertensive Agents; | 2020 |
Reply to letter regarding 'Methyldopa versus Nifedipine or no medication for treatment of chronic hypertension during pregnancy'.
Topics: Antihypertensive Agents; Female; Humans; Hypertension; Methyldopa; Nifedipine; Pre-Eclampsia; Pregna | 2020 |
Different tocolytics appear equally safe long-term but we need both higher follow-up rates and placebo-controlled trials in future.
Topics: Child; Female; Follow-Up Studies; Humans; Nifedipine; Pregnancy; Tocolysis; Tocolytic Agents; Vasoto | 2020 |
What if there is no reliable and appropriate medication for pregnancy hypertension available in Indonesian primary care?
Topics: Antihypertensive Agents; Female; Humans; Hypertension, Pregnancy-Induced; Indonesia; Maternal Health | 2020 |
Regulation of magnesium sulfate combined with nifedipine and labetalol on disease-related molecules in serum and placenta in the treatment of preeclampsia.
Topics: Administration, Oral; Adult; E-Selectin; Female; Humans; Labetalol; Magnesium Sulfate; Nifedipine; P | 2020 |
Effects of nifedipine on fetal cardiac function in preterm labor.
Topics: Adult; Cardiotocography; Female; Fetal Heart; Fetus; Humans; Infant, Newborn; Nifedipine; Obstetric | 2020 |
Pregnancy-Related Hormones Increase Nifedipine Metabolism in Human Hepatocytes by Inducing CYP3A4 Expression.
Topics: Cytochrome P-450 CYP3A; Female; Hepatocytes; Humans; Nifedipine; Pregnancy; Progesterone; Tandem Mas | 2021 |
Semiautonomous Treatment Algorithm for the Management of Severe Hypertension in Pregnancy.
Topics: Adult; Algorithms; Antihypertensive Agents; Female; Humans; Hypertension, Pregnancy-Induced; Labetal | 2021 |
Anoctamin 1 antagonism potentiates conventional tocolytic-mediated relaxation of pregnant human uterine smooth muscle.
Topics: Anoctamin-1; Benzbromarone; Female; Gene Expression Regulation; Humans; Muscle Relaxation; Muscle, S | 2021 |
Effects of nifedipine on endothelial function, assessed by flow-mediated vasodilatation in pregnant patients.
Topics: Adult; Female; Humans; Infant; Infant, Newborn; Nifedipine; Obstetric Labor, Premature; Pregnancy; P | 2022 |
Conflicting Nongenomic Effects of Progesterone in the Myometrium of Pregnant Rats.
Topics: Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Female; Hormo | 2021 |
Preventing Recurrent Preeclampsia by Tailored Treatment of Nonphysiologic Hemodynamic Adjustments to Pregnancy.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Hemodynamics; Humans; Labetalol; Methyldopa; | 2021 |
Calcium signaling cascades differentially regulate PGF
Topics: Animals; Buffaloes; Calcium; Calcium Channel Blockers; Calcium Signaling; Dinoprost; Female; Myometr | 2021 |
Committee Opinion No. 692 Summary: Emergent Therapy for Acute-Onset, Severe Hypertension During Pregnancy and the Postpartum Period.
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Drug Administration Routes; E | 2017 |
Committee Opinion No. 692: Emergent Therapy for Acute-Onset, Severe Hypertension During Pregnancy and the Postpartum Period.
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Drug Administration Routes; E | 2017 |
Polymerization-Incompetent Uromodulin in the Pregnant Stroke-Prone Spontaneously Hypertensive Rat.
Topics: Animals; Antihypertensive Agents; Female; Hypertension, Pregnancy-Induced; Kidney; Nifedipine; Polym | 2017 |
Treating normal early gestation placentae with preeclamptic sera produces extracellular micro and nano vesicles that activate endothelial cells.
Topics: Cells, Cultured; Endothelial Cells; Extracellular Vesicles; Female; HMGB1 Protein; Humans; Immune Se | 2017 |
A trial of oral nifedipine and oral labetalol in preeclampsia hypertensive emergency treatment.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Administratio | 2017 |
A Physiologically Based Pharmacokinetic Model for Pregnant Women to Predict the Pharmacokinetics of Drugs Metabolized Via Several Enzymatic Pathways.
Topics: Caffeine; Cytochrome P-450 Enzyme System; Diazepam; Female; Granisetron; Humans; Metoprolol; Metroni | 2018 |
Nifedipine Prevents Apoptosis of Alcohol-Exposed First-Trimester Trophoblast Cells.
Topics: Apoptosis; Calcium; Calcium Channel Blockers; Cell Line; Ethanol; Female; Humans; Nifedipine; Placen | 2018 |
Axon Initial Segment Structural Plasticity is Involved in Seizure Susceptibility in a Rat Model of Cortical Dysplasia.
Topics: Animals; Axon Initial Segment; Axons; Disease Models, Animal; Disease Susceptibility; Electroencepha | 2018 |
The effect of labetalol and nifedipine MR on blood pressure in women with chronic hypertension in pregnancy.
Topics: Adrenergic Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chronic D | 2018 |
Effect of pregnancy on cooling tone and rhythmic contractions of the rat urinary bladder.
Topics: Animals; Calcium; Calcium Channel Blockers; Female; Hypothermia, Induced; Indoles; Muscle Contractio | 2018 |
Pregnancy-induced complications in IgA nephropathy: A case report.
Topics: Adult; Antihypertensive Agents; Benzimidazoles; Benzoates; Biopsy; Blood Pressure; Cyclophosphamide; | 2018 |
An effect of maternal nifedipine therapy on fetoplacental blood flow: a prospective study.
Topics: Female; Fetus; Humans; Middle Cerebral Artery; Nifedipine; Placenta; Pregnancy; Prospective Studies; | 2018 |
Atypical presentation and imaging features of postpartum posterior reversible encephalopathy syndrome.
Topics: Adult; Female; HELLP Syndrome; Humans; Magnesium Sulfate; Magnetic Resonance Imaging; Nifedipine; Po | 2019 |
The effects of nifedipine and ivabradine on the functionality of the early rat embryonic heart. Are these drugs a risk in early human pregnancy?
Topics: Animals; Female; Heart; Heart Arrest; Heart Rate; Humans; Ivabradine; Nifedipine; Pregnancy; Rats; R | 2019 |
The importance of cost considerations in preterm birth trials.
Topics: Cost-Benefit Analysis; Female; Humans; Infant, Newborn; Nifedipine; Pregnancy; Premature Birth; Vaso | 2019 |
Sildenafil citrate in obstetrics - caution is advised.
Topics: Female; Humans; Nifedipine; Obstetric Labor, Premature; Obstetrics; Pregnancy; Sildenafil Citrate | 2019 |
Raynaud Phenomenon of the Nipple: An Under-Recognized Condition.
Topics: Adult; Breast Diseases; Diagnosis, Differential; Female; Humans; Nifedipine; Nipples; Pain; Pregnanc | 2019 |
In vitro comparison of liposomal drug delivery systems targeting the oxytocin receptor: a potential novel treatment for obstetric complications.
Topics: Animals; Cell Death; Cell Line; Drug Delivery Systems; Endocytosis; Female; Humans; Immunoglobulin G | 2019 |
Cumulative Risk of the Oxytocin Receptor Gene Interacts with Prenatal Exposure to Oxytocin Receptor Antagonist to Predict Children's Social Communication Development.
Topics: Adult; Autism Spectrum Disorder; Child; Child, Preschool; Communication Disorders; Drug Therapy, Com | 2019 |
Case Report: Optical Coherence Tomography Can Find Typical Features in Pregnancy-induced Hypertension with Retinopathy.
Topics: Adult; Blood Pressure; Drug Therapy, Combination; Female; Fluorescein Angiography; Humans; Hypertens | 2019 |
Oral regimen management of acute hypertension in pregnancy.
Topics: Antihypertensive Agents; Female; Humans; Hypertension; Labetalol; Methyldopa; Nifedipine; Pregnancy; | 2019 |
Acute pulmonary failure due to pulmonary edema during tocolytic therapy with nifedipine.
Topics: Acute Disease; Adult; Female; Fetal Membranes, Premature Rupture; Humans; Nifedipine; Obstetric Labo | 2013 |
Enhanced contractility in pregnancy is associated with augmented TRPC3, L-type, and T-type voltage-dependent calcium channel function in rat uterine radial artery.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Endothelium, | 2013 |
Chronic vasodilation increases renal medullary PDE5A and α-ENaC through independent renin-angiotensin-aldosterone system pathways.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pr | 2013 |
Change of hs-CRP, sVCAM-1, NT-proBNP levels in patients with pregnancy-induced hypertension after therapy with magnesium sulfate and nifedipine.
Topics: Adult; Antihypertensive Agents; Biomarkers; C-Reactive Protein; Calcium Channel Blockers; Endotheliu | 2013 |
Maternal hypotension during fetoscopic surgery: incidence and its impact on fetal survival outcomes.
Topics: Adult; Cohort Studies; Female; Fetal Death; Fetofetal Transfusion; Fetoscopy; Humans; Hypotension; I | 2013 |
Pregnancy outcomes and successful rate of nifedipine therapeutic protocol implementation in a hospital of San Juan.
Topics: Adolescent; Adult; Dexamethasone; Drug Administration Schedule; Drug Evaluation; Female; Fetal Membr | 2013 |
The effect on rat embryonic heart rate of Na+, K+, and Ca2+ channel blockers, and the human teratogen phenytoin, changes with gestational age.
Topics: Animals; Calcium Channel Blockers; Female; Gestational Age; Heart Rate, Fetal; Lidocaine; Nifedipine | 2013 |
Preterm labor: current tocolytic options for the treatment of preterm labor.
Topics: Adrenergic beta-Agonists; Female; Glucocorticoids; Humans; Infant, Newborn; Nifedipine; Obstetric La | 2014 |
Effect of magnesium sulfate and nifedipine on the risk of developing pulmonary edema in preterm births.
Topics: Adult; Azithromycin; Case-Control Studies; Drug Synergism; Erythromycin; Female; Humans; Infant, New | 2014 |
Leukotriene receptor antagonist as a novel tocolytic in an in vitro model of human uterine contractility.
Topics: Acetates; Adult; Area Under Curve; Calcium; Cyclopropanes; Extraembryonic Membranes; Female; Humans; | 2014 |
Cerebral perfusion pressure in women with preeclampsia is elevated even after treatment of elevated blood pressure.
Topics: Adult; Antihypertensive Agents; Arterial Pressure; Blood Flow Velocity; Case-Control Studies; Cerebr | 2014 |
High-sucrose diets in pregnancy alter angiotensin II-mediated pressor response and microvessel tone via the PKC/Cav1.2 pathway in rat offspring.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Dietary | 2014 |
What is the risk of preterm delivery after arrested preterm labor?
Topics: Adult; Case-Control Studies; Cervical Length Measurement; Cervix Uteri; Cohort Studies; Female; Fibr | 2015 |
Role of adjunctive medical therapy in the fetoscopic surgical treatment of twin-twin transfusion syndrome.
Topics: Calcium Channel Blockers; Cardiomyopathies; Female; Fetofetal Transfusion; Fetoscopy; Humans; Nifedi | 2014 |
Store-operated Ca²⁺ entry and depolarization explain the anomalous behaviour of myometrial SR: effects of SERCA inhibition on electrical activity, Ca²⁺ and force.
Topics: Action Potentials; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium S | 2014 |
Hemodynamic effects of nifedipine tocolysis.
Topics: Adolescent; Adult; Blood Pressure; Female; Heart Rate; Humans; Hypotension; Nifedipine; Pregnancy; R | 2015 |
[Adverse effects and hemodynamic effects of nifedipine as a tocolytic].
Topics: Blood Pressure; Drug-Related Side Effects and Adverse Reactions; Female; Heart Rate; Heart Rate, Fet | 2015 |
The effect of nifedipine tocolysis on Doppler indices of the uterine and umbilical arteries.
Topics: Adolescent; Adult; Cohort Studies; Female; Follow-Up Studies; Humans; Nifedipine; Pregnancy; Prospec | 2015 |
[Tocolysis with nifedipin; its use in current practice].
Topics: Calcium Channel Blockers; Female; Gestational Age; Humans; Longitudinal Studies; Nifedipine; Obstetr | 2014 |
Severe resistant maternal hypotension following tocolysis with nifedipine.
Topics: Adolescent; Cesarean Section; Female; Fetal Membranes, Premature Rupture; Fluid Therapy; Gestational | 2014 |
The influence of ritodrine alone or in combination with nifedipine on maternal cardiovascular side effects and pregnancy outcomes.
Topics: Adult; Birth Weight; Calcium Channel Blockers; Cardiovascular Diseases; Cardiovascular System; Dose- | 2014 |
The reduction of circulating levels of IL-6 in pregnant women with preeclampsia by magnesium sulphate and nifedipine: In vitro evidence for potential mechanisms.
Topics: Adolescent; Adult; Endothelial Cells; Female; Humans; Interleukin-6; Magnesium Sulfate; Nifedipine; | 2015 |
Analysis of nifedipine in human plasma and amniotic fluid by liquid chromatography-tandem mass spectrometry and its application to clinical pharmacokinetics in hypertensive pregnant women.
Topics: Adult; Amniotic Fluid; Antihypertensive Agents; Chromatography, High Pressure Liquid; Female; Humans | 2015 |
Oral nifedipine or intravenous labetalol for severe hypertension?
Topics: Antihypertensive Agents; Female; Humans; Hypertension, Pregnancy-Induced; Labetalol; Nifedipine; Pra | 2016 |
Signaling Mechanisms in the Nitric Oxide Donor- and Amphetamine-Induced Dopamine Release in Mesencephalic Primary Cultured Neurons.
Topics: Amphetamine; Animals; Calcium Channel Blockers; Cells, Cultured; Dizocilpine Maleate; Dopamine; Embr | 2016 |
[Effect of Magnesium Sulfate, Nifedipine Tablet Combined Salvia Injection on ET-1/NO, TXA2/PGI2 and Hemorheology of Preeclampsia Patients].
Topics: Drug Therapy, Combination; Drugs, Chinese Herbal; Endothelin-1; Epoprostenol; Female; Hemorheology; | 2015 |
Effects of d- and l-limonene on the pregnant rat myometrium in vitro.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Cyclic AMP; Cyclohexenes; Female; Indoles; Limo | 2015 |
Abnormal uterine artery remodelling in the stroke prone spontaneously hypertensive rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Female; Gestational Age; Hypertension; Nifedipine; | 2016 |
Severe maternal morbidity in a large cohort of women with acute severe intrapartum hypertension.
Topics: Adult; Antihypertensive Agents; California; Female; Humans; Hydralazine; Hypertension, Pregnancy-Ind | 2016 |
Tocolysis and preterm labour.
Topics: Calcium Channel Blockers; Female; Humans; Nifedipine; Pregnancy; Premature Birth; Tocolytic Agents; | 2016 |
The Effect of Maternal Antihypertensive Drugs on the Cerebral, Renal and Splanchnic Tissue Oxygen Extraction of Preterm Neonates.
Topics: Antihypertensive Agents; Brain; Cerebrovascular Circulation; Female; Gestational Age; Hemodynamics; | 2016 |
Nifedipine Induced Gingival Hyperplasia in Pregnancy: A Case Report.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Female; Gingival Hyperplasia; Humans; Nifedipine; | 2017 |
Nifedipine increases fetoplacental perfusion.
Topics: Adult; Female; Hemodynamics; Humans; Nifedipine; Placental Circulation; Pregnancy; Premature Birth; | 2017 |
Drug delivery to the human and mouse uterus using immunoliposomes targeted to the oxytocin receptor.
Topics: Albuterol; Animals; Drug Delivery Systems; Female; Indomethacin; Liposomes; Mice; Myometrium; Nifedi | 2017 |
Impact of tamsulosin and nifedipine on contractility of pregnant rat ureters in vitro
Topics: Animals; Female; Kidney Calculi; Methacholine Chloride; Nifedipine; Pregnancy; Rats; Rats, Sprague-D | 2018 |
Extra and intracellular calcium signaling pathway(s) differentially regulate histamine-induced myometrial contractions during early and mid-pregnancy stages in buffaloes (Bubalus bubalis).
Topics: Animals; Buffaloes; Calcium; Calcium Channel Blockers; Calcium Signaling; Female; Histamine; Myometr | 2017 |
Functional involvement of protein kinase C, Rho-kinase and TRPC3 decreases while PLC increases with advancement of pregnancy in mediating oxytocin-induced myometrial contractions in water buffaloes (Bubalus bubalis).
Topics: Animals; Buffaloes; Calcium Channel Blockers; Enzyme Inhibitors; Female; Gene Expression Regulation, | 2017 |
Hypertension and generalised tonic-clonic seizures occurring 41 days after elective caesarian section.
Topics: Adult; Cesarean Section; Eclampsia; Elective Surgical Procedures; Epilepsy, Generalized; Epilepsy, T | 2008 |
[Treatment of preterm delivery with calcium channel blockers--Nifedipine].
Topics: Calcium Channel Blockers; Female; Gestational Age; Humans; Nifedipine; Obstetric Labor, Premature; P | 2007 |
Side-effect and vital sign profile of nifedipine as a tocolytic for preterm labour.
Topics: Administration, Sublingual; Adult; Analysis of Variance; Blood Pressure; Chi-Square Distribution; Do | 2008 |
K+ channel inhibition modulates the biochemical and morphological differentiation of human placental cytotrophoblast cells in vitro.
Topics: 4-Aminopyridine; Arachidonic Acids; Barium Compounds; Calcium Channel Blockers; Cell Differentiation | 2008 |
Management of recurrent preterm labor in twin gestations with nifedipine tocolysis.
Topics: Administration, Oral; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gestat | 2008 |
Allopregnanolone-induced rise in intracellular calcium in embryonic hippocampal neurons parallels their proliferative potential.
Topics: Anesthetics; Animals; Bicuculline; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell | 2008 |
[Non-invasive ventilation for pulmonary edema associated with tocolytic agents during labour for a twin pregnancy].
Topics: Adult; Apgar Score; Delivery, Obstetric; Female; Humans; Infant, Newborn; Nicardipine; Nifedipine; P | 2008 |
Tocolytics and preterm labour.
Topics: Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnancy Complications; Tocolyti | 2009 |
Adverse reactions to tocolytics. Atosiban v nifedipine.
Topics: Female; Humans; Nifedipine; Pregnancy; Randomized Controlled Trials as Topic; Tocolytic Agents; Vaso | 2009 |
KCC2 expression promotes the termination of cortical interneuron migration in a voltage-sensitive calcium-dependent manner.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Calcium; Calcium Channel Blockers; Calcium Chan | 2009 |
Calcium-activated chloride currents prolongs the duration of contractions in pregnant rat myometrial tissue.
Topics: Animals; Anthracenes; Calcium Channel Blockers; Calcium Channels, L-Type; Chloride Channels; Chlorid | 2009 |
Functional analysis of calcium channel-mediated exocytosis in synaptic terminals by FM imaging technique.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Diagnostic Imaging; Em | 2009 |
Modification of the effect of nifedipine in the pregnant rat myometrium: the influence of progesterone and terbutaline.
Topics: Animals; Calcium Channels; Drug Administration Schedule; Drug Interactions; Female; Gestational Age; | 2009 |
Doppler velocimetry of the uterine, umbilical and fetal middle cerebral arteries in pregnant women undergoing tocolysis with oral nifedipine.
Topics: Adolescent; Adult; Blood Flow Velocity; Female; Gestational Age; Humans; Maternal-Fetal Exchange; Mi | 2009 |
[Methyldopa-induced acute reactive hepatitis in pregnancy, drug-metabolizing capacity of the liver].
Topics: Adrenergic alpha-Agonists; Adult; Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Blood Pres | 2010 |
[Hypertensive urgency or hypertensive emergency?].
Topics: Adult; Antihypertensive Agents; Blood Pressure Determination; Emergencies; Female; Follow-Up Studies | 2010 |
[Management of pre-term labor: use of nifedipine in Conakry, Guinea].
Topics: Apgar Score; Delivery, Obstetric; Dizziness; Female; Headache; Humans; Infant, Newborn; Nifedipine; | 2010 |
Does sildenafil citrate affect myometrial contractile response to nifedipine in vitro?
Topics: Adult; Biopsy; Calcium Channel Blockers; Female; Humans; In Vitro Techniques; Myometrium; Nifedipine | 2010 |
Atrioventricular conduction and arrhythmias at the initiation of beating in embryonic mouse hearts.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Atrioventricular Block; Calcium; Calcium Channel B | 2010 |
[Nifedipine or nicardipine in management of threatened preterm delivery: an observational population-based study].
Topics: Adult; Calcium Channel Blockers; Female; France; Humans; Nicardipine; Nifedipine; Pregnancy; Prematu | 2010 |
Effect of maternal body mass index on in vitro response to tocolytics in term myometrium.
Topics: Adult; Area Under Curve; Biopsy; Body Mass Index; Female; Humans; In Vitro Techniques; Indomethacin; | 2010 |
Improved recipient survival with maternal nifedipine in twin-twin transfusion syndrome complicated by TTTS cardiomyopathy undergoing selective fetoscopic laser photocoagulation.
Topics: Cardiomyopathies; Case-Control Studies; Female; Fetofetal Transfusion; Fetoscopy; Humans; Laser Coag | 2010 |
Hypotension in normotensive pregnant women treated with nifedipine as a tocolytic drug.
Topics: Adolescent; Adult; Female; Humans; Hypotension; Middle Aged; Nifedipine; Obstetric Labor, Premature; | 2011 |
Potentiation of the uterus-relaxing effects of β-adrenergic agonists with nifedipine: studies on rats and the human myometrium.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Drug Synergism; Drug Therapy, Combination; Female; Hum | 2010 |
Chronic vasodilation produces plasma volume expansion and hemodilution in rats: consequences of decreased effective arterial blood volume.
Topics: Animals; Blood Pressure; Blood Volume; Cyclic Nucleotide Phosphodiesterases, Type 5; Female; Hemodil | 2011 |
Nifedipine for the treatment of preterm labor in twin and singleton pregnancies.
Topics: Adult; Databases, Factual; Female; Gestational Age; Hospitals, University; Humans; Indomethacin; Inf | 2011 |
Effects of methyldopa and nifedipine on uteroplacental and fetal hemodynamics in gestational hypertension.
Topics: Adult; Antihypertensive Agents; Female; Hemodynamics; Humans; Hypertension, Pregnancy-Induced; Methy | 2012 |
Maternal and fetal haemodynamic effects of nifedipine in normotensive pregnant women.
Topics: Adult; Blood Pressure; Cardiac Output; Echocardiography; Female; Hemodynamics; Humans; Infant, Newbo | 2011 |
[Investigation of uterus-relaxing effects of nifedipine in the presence of terbutaline and K(+)-channel blockers].
Topics: Animals; Female; Humans; Nifedipine; Potassium Channel Blockers; Pregnancy; Pregnancy, Animal; Rats; | 2010 |
False-positive amphetamine toxicology screen results in three pregnant women using labetalol.
Topics: Adult; Amphetamine; Antihypertensive Agents; Cesarean Section; Chronic Disease; Cocaine; Cross React | 2011 |
AAV-mediated gene replacement, either alone or in combination with physical and pharmacological agents, results in partial and transient protection from photoreceptor degeneration associated with betaPDE deficiency.
Topics: Animals; Calcium Channel Blockers; Chlorocebus aethiops; Combined Modality Therapy; COS Cells; Cycli | 2011 |
Pregnancy outcomes in a recurrent preterm birth prevention clinic.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Cervical Length Measurement; Clinical Protocols; Cohort Studies | 2011 |
Successful management of a high-risk pregnancy with polyhydramnios, IUGR and recurrent pregnancy loss in a chronic renal failure patient: a case report.
Topics: Abortion, Habitual; Adult; Amniotic Fluid; Betamethasone; Birth Weight; Female; Fetal Growth Retarda | 2011 |
Antenatal calcium channel blocker exposure and subsequent patent ductus arteriosus in extremely low-birth-weight infants.
Topics: Calcium Channel Blockers; Case-Control Studies; Ductus Arteriosus, Patent; Female; Humans; Infant, N | 2012 |
['Steroid psychosis' during treatment for premature labour].
Topics: Adult; Antipsychotic Agents; Betamethasone; Female; Glucocorticoids; Haloperidol; Humans; Nifedipine | 2011 |
[Takayasu's arteritis in pregnancy: report seven cases].
Topics: Adult; Antihypertensive Agents; Cesarean Section; Female; Fetal Growth Retardation; Follow-Up Studie | 2011 |
Mineralocorticoids participate in the reduced vascular reactivity of pregnant rats.
Topics: Aldosterone; Animals; Aorta, Thoracic; Benzimidazoles; Calcium Channel Blockers; Canrenoic Acid; Cro | 2012 |
Inhibition of uterine contractility with various tocolytics with and without progesterone: in vitro studies.
Topics: Adult; Female; Humans; Indomethacin; Magnesium Sulfate; Myometrium; Nifedipine; Obstetric Labor, Pre | 2012 |
Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons.
Topics: 4-Aminopyridine; Analysis of Variance; Animals; Bicuculline; Calcium Channel Blockers; Cells, Cultur | 2012 |
Expression of selected genes in preterm premature rupture of fetal membranes.
Topics: Adult; Calcium Channel Blockers; Calcium Channels, L-Type; Celecoxib; Cyclooxygenase 2 Inhibitors; D | 2012 |
Nifedipine versus labetalol in the treatment of hypertensive disorders of pregnancy.
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Female; Humans; Hypertension, Pregnancy-Induc | 2012 |
[Comparison of the rate of maternal complications of nifedipine and nicardipine in cases of preterm labor: historical study on two consecutive periods].
Topics: Adult; Calcium Channel Blockers; Female; France; Humans; Nicardipine; Nifedipine; Obstetric Labor, P | 2012 |
Nifedipine pharmacokinetics are influenced by CYP3A5 genotype when used as a preterm labor tocolytic.
Topics: Adolescent; Adult; Alleles; Cohort Studies; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug | 2013 |
Vaginal delivery in a parturient excessively anticoagulated with fondaparinux.
Topics: Adult; Analgesics, Opioid; Anticoagulants; Calcium Channel Blockers; Delivery, Obstetric; Dose-Respo | 2012 |
Calcium channel blockers prevent endothelial cell activation in response to necrotic trophoblast debris: possible relevance to pre-eclampsia.
Topics: Adolescent; Adult; Calcium Channel Blockers; Case-Control Studies; Cell Adhesion; Cell Proliferation | 2012 |
Characterization of the tissue-level Ca2+ signals in spontaneously contracting human myometrium.
Topics: Action Potentials; Calcium; Calcium Channel Blockers; Calcium Signaling; Female; Humans; Isometric C | 2012 |
Maternal atrial fibrillation after sequential use of nifedipine and atosiban for treatment of preterm labor: case report.
Topics: Adult; Atrial Fibrillation; Drug Therapy, Combination; Female; Humans; Nifedipine; Obstetric Labor, | 2013 |
Atosiban and nifedipine in the suppression of pre-term labour: a comparative study.
Topics: Adult; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Retrospective Studies; Toc | 2013 |
The effects of extracellular calcium-sensing receptor ligands on the contractility of pregnant human myometrium in vitro.
Topics: Benzamides; Calcium Channel Blockers; Cinacalcet; Cyclohexylamines; Dose-Response Relationship, Drug | 2013 |
Maternal antihypertensive drugs may influence cerebral oxygen extraction in preterm infants during the first days after birth.
Topics: Antihypertensive Agents; Case-Control Studies; Cerebral Cortex; Cerebrovascular Circulation; Female; | 2013 |
Norepinephrine enhances fibrosis mediated by TGF-beta in cardiac fibroblasts.
Topics: Activating Transcription Factor 2; Animals; Animals, Newborn; Blotting, Western; Cell Division; Coll | 2002 |
Effects of mibefradil on uterine contractility.
Topics: Animals; Calcium Channel Blockers; Calcium Chloride; Drug Interactions; Female; Mibefradil; Nifedipi | 2002 |
Magnesium sulfate for preeclampsia.
Topics: Anticonvulsants; Eclampsia; Female; History, 17th Century; History, 18th Century; History, 20th Cent | 2003 |
Nifedipine-induced changes in body composition in hypertensive patients at term.
Topics: Adult; Blood Pressure; Body Composition; Body Water; Calcium Channel Blockers; Electric Impedance; F | 2003 |
Effects of L-type Ca(2+)-channel blockade, K(+)(ATP)-channel opening and nitric oxide on human uterine contractility in relation to gestational age and labour.
Topics: Adult; Arginine; Calcium Channel Blockers; Calcium Channels, L-Type; Female; Gestational Age; Humans | 2003 |
Windows of therapeutic opportunity on fetal growth retardation induced by transient intrauterine ischemia in rats.
Topics: Animals; Cyclic N-Oxides; Dizocilpine Maleate; Female; Fetal Growth Retardation; Fetal Hypoxia; Isch | 2002 |
Gabapentin blocks L-type and P/Q-type Ca2+ channels involved in depolarization-stimulated nitric oxide synthase activity in primary cultures of neurons from mouse cerebral cortex.
Topics: Acetates; Amines; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, P-T | 2003 |
[Effect of diumancal, foridon, nifedipine, and verapamil on the myometrium potentials in pregnant rats].
Topics: Action Potentials; Animals; Calcium Channel Blockers; Electrodes; Female; Myometrium; Nifedipine; Pr | 2002 |
Effects of acetylcholinesterase and butyrylcholinesterase on cell survival, neurite outgrowth, and voltage-dependent calcium currents of embryonic ventral mesencephalic neurons.
Topics: Acetylcholinesterase; Animals; Astrocytes; Butyrylcholinesterase; Calcium Channel Blockers; Calcium | 2003 |
Maternal admission characteristics as risk factors for preterm birth.
Topics: Adult; Confidence Intervals; Female; Follow-Up Studies; Gestational Age; Hospitals, University; Huma | 2004 |
Long-term hypoxia alters calcium regulation in near-term ovine myometrium.
Topics: Animals; Calcium; Calcium Channel Blockers; Chronic Disease; Female; Gestational Age; Hypoxia; Myome | 2004 |
Pregnancy and economic outcomes in patients treated for recurrent preterm labor.
Topics: Administration, Oral; Adult; Case-Control Studies; Cost-Benefit Analysis; Costs and Cost Analysis; F | 2004 |
Maternal hypoxia associated with nifedipine for threatened preterm labour.
Topics: Adult; Dyspnea; Female; Heart Septal Defects, Ventricular; Humans; Hypoxia; Nifedipine; Obstetric La | 2004 |
Preeclampsia with abnormal liver function tests is associated with cholestasis in a subgroup of cases.
Topics: Adrenergic alpha-Agonists; Adult; Anti-Inflammatory Agents; Bile Acids and Salts; Biomarkers; Blood | 2004 |
Reply to article by King et al.
Topics: Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnan | 2004 |
Emerging issues over the choice of nifedipine, beta-agonists and atosiban for tocolysis in spontaneous preterm labour--a proposed systematic review by the International Preterm Labour Council.
Topics: Adrenergic beta-Agonists; Europe; Evidence-Based Medicine; Female; Humans; International Cooperation | 2004 |
Increased Na+ intake during gestation in rats is associated with enhanced vascular reactivity and alterations of K+ and Ca2+ function.
Topics: Animals; Aorta; Arginine Vasopressin; Blood Pressure; Calcium; Calcium Channel Blockers; Female; Mal | 2004 |
Response to "The drugs we deserve".
Topics: Calcium Channel Blockers; Double-Blind Method; Female; Humans; Nifedipine; Obstetric Labor, Prematur | 2004 |
Anti-hypertensive therapy and the feto-placental circulation: effects on umbilical artery resistance.
Topics: Adult; Antihypertensive Agents; Dose-Response Relationship, Drug; Female; Fetus; Humans; Hydralazine | 2004 |
The short-term effect of nifedipine tocolysis on placental, fetal cerebral and atrioventricular Doppler waveforms.
Topics: Adult; Cerebral Arteries; Echocardiography, Doppler; Female; Humans; Nifedipine; Obstetric Labor, Pr | 2004 |
Choosing calcium channel blockers for pregnant women with paroxysmal supraventriclar tachycardia and preterm labor: a case report.
Topics: Adult; Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; | 2004 |
Anesthetic management of Cesarean delivery in a patient with hypoplastic anemia and severe pre-eclampsia.
Topics: Adult; Anemia, Hypoplastic, Congenital; Anesthesia, General; Anesthesia, Obstetrical; Blood Pressure | 2004 |
L-type Ca2+ channel blockers promote Ca2+ accumulation when dopamine receptors are activated in striatal neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Calcium; Calcium Channel Blocke | 2004 |
Severe hypotension and fetal death due to tocolysis with nifedipine.
Topics: Adult; Female; Fetal Death; Humans; Hypotension; Nifedipine; Obstetric Labor, Premature; Pregnancy; | 2005 |
Comment on the article "Acute pulmonary oedema during nicardipine therapy for premature labour. Report of five cases" by Vaast P., et al. [Eur J Obstet Gynecol Reprod Biol 2004;113:98-9].
Topics: Calcium Channel Blockers; Female; Humans; Nicardipine; Nifedipine; Obstetric Labor, Premature; Pregn | 2005 |
[Licensed or non-licensed tocolysis?].
Topics: Female; Humans; Nifedipine; Pregnancy; Tocolysis; Tocolytic Agents; Vasotocin | 2005 |
[Tocolysis by first intention with nifedipine].
Topics: Adrenergic beta-Agonists; Calcium Channel Blockers; Female; Humans; Nifedipine; Placebos; Pregnancy; | 2005 |
Stimulation of P2X7 receptors elevates Ca2+ and kills retinal ganglion cells.
Topics: Adenosine Triphosphate; Animals; Benzenesulfonates; Calcium; Calcium Channel Blockers; Cell Culture | 2005 |
Permanent visual deficits secondary to the HELLP syndrome.
Topics: Adult; Blood Pressure; Brain Infarction; Drug Therapy, Combination; Eclampsia; Female; Furosemide; H | 2005 |
Nifedipine for severe hypertension in pregnancy: emotion or evidence?
Topics: Acute Disease; Canada; Capsules; Female; Humans; Hypertension, Pregnancy-Induced; Nifedipine; Pregna | 2005 |
Therapy with both magnesium sulfate and nifedipine does not increase the risk of serious magnesium-related maternal side effects in women with preeclampsia.
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Case-Control Studies; Cohort Studies; Drug | 2005 |
Severe hyperinsulinaemic hypoglycaemia in a baby born to a mother taking oral ritodrine therapy for preterm labour.
Topics: Adult; Calcium Channel Blockers; Female; Humans; Hyperinsulinism; Hypoglycemia; Infant, Newborn; Ins | 2005 |
Late-gestation rat myometrial cells express multiple isoforms of phospholipase A2 that mediate PCB 50-induced release of arachidonic acid with coincident prostaglandin production.
Topics: Animals; Arachidonic Acid; Calcium Channels, L-Type; Cells, Cultured; Chelating Agents; Dose-Respons | 2005 |
The treatment of severe hypertension in pregnancy: a review of current practice and knowledge in West-Midlands maternity units.
Topics: Antihypertensive Agents; Female; Hospital Units; Humans; Hydralazine; Hypertension, Pregnancy-Induce | 2004 |
Severe hypotension and fetal death due to tocolysis with nifedipine.
Topics: Female; Humans; Hypotension; Nifedipine; Obstetric Labor, Premature; Pregnancy; Tocolysis; Tocolytic | 2005 |
Severe hypotension and fetal death due to tocolysis with nifedipine.
Topics: Female; Fetal Death; Humans; Hypotension; Nifedipine; Pregnancy; Pregnancy Complications, Cardiovasc | 2005 |
Severe hypotension and fetal death due to tocolysis with nifedipine.
Topics: Female; Fetal Death; Health Care Surveys; Humans; Hypotension; Nifedipine; Obstetric Labor, Prematur | 2005 |
[Tocolysis with nifedipine: its use in current practice].
Topics: Adult; Evidence-Based Medicine; Female; Humans; Nifedipine; Obstetric Labor, Premature; Patient Sele | 2005 |
[Tocolysis with nifedipine: its use in current practice].
Topics: Adult; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Tocolysis; Tocolytic Agent | 2005 |
Effect of tocolytics on interleukin-8 production by human amniotic and decidual cells.
Topics: Amnion; Cells, Cultured; Decidua; Endotoxins; Female; Humans; Interleukin-8; Magnesium Sulfate; Nife | 2006 |
[Tocolysis with nifedipine: its use in current practice. Gynecol Obstet Fertil 2005;33:483-7].
Topics: Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnancy Outcome; Tocolysis; Toc | 2006 |
Pregnancy-induced modulation of calcium mobilization and down-regulation of Rho-kinase expression contribute to attenuated vasopressin-induced contraction of the rat aorta.
Topics: Amides; Animals; Aorta; Arginine Vasopressin; Calcium; Calcium Channel Blockers; Dose-Response Relat | 2006 |
[Tocolysis with nifedipine: its use in current practice. Gynecol Obstet Fertil 2005;33:483-7].
Topics: Female; Humans; Nicardipine; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnancy Outcome; P | 2006 |
Hypothyroid state reduces calcium channel function in 18-day pregnant rat uterus.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Diltiazem; Female; Hypothyroidism; Methimazole; | 2006 |
Nifedipine therapy for preterm labor: effects on placental, fetal cerebral and atrioventricular Doppler parameters in the first 48 hours.
Topics: Adult; Analysis of Variance; Arteries; Blood Pressure; Diastole; Female; Heart Rate; Heart Valves; H | 2006 |
Paraparesis with complete recovery in antepartum eclampsia.
Topics: Adult; Antihypertensive Agents; Brain Diseases; Delivery, Obstetric; Eclampsia; Female; Follow-Up St | 2006 |
Nifedipine tocolysis associated atrial fibrillation responds to DC cardioversion.
Topics: Adult; Atrial Fibrillation; Electric Countershock; Female; Humans; Nifedipine; Obstetric Labor, Prem | 2006 |
Acute pulmonary edema during tocolytic therapy with nifedipine.
Topics: Acute Disease; Adult; Calcium Channel Blockers; Female; Humans; Nifedipine; Pregnancy; Pulmonary Ede | 2006 |
[Emergency checklist in hypertensive crisis].
Topics: Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Blockers; Clonidine; Diuretic | 2006 |
PRES: posterior or potentially reversible encephalopathy syndrome?
Topics: Adult; Anti-Inflammatory Agents; Anticonvulsants; Antihypertensive Agents; Brain; Brain Diseases; Cl | 2006 |
Nifedipine suppresses self-injurious behaviors in animals.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2007 |
Vasorelaxant effect of levcromakalim on isolated umbilical arteries of preeclamptic women.
Topics: Adult; Case-Control Studies; Cromakalim; Dose-Response Relationship, Drug; Female; Humans; In Vitro | 2007 |
Massive pre-placental and subchorionic haematoma.
Topics: 17 alpha-Hydroxyprogesterone Caproate; Adult; Female; Fetal Membranes, Premature Rupture; Hematoma; | 2006 |
[Indications for respiratory complications during the use of oral nifedipine as a tocolytic agent, especially in patients with multiple pregnancies].
Topics: Adult; Dyspnea; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnancy Outcome | 2007 |
Myometrial expression of small conductance Ca2+-activated K+ channels depresses phasic uterine contraction.
Topics: Animals; Apamin; Calcium; Doxycycline; Female; In Vitro Techniques; Indoles; Isometric Contraction; | 2007 |
Nifedipine-tocolysis-associated atrial fibrillation responds to DC cardioversion.
Topics: Atrial Fibrillation; Calcium Channel Blockers; Electric Countershock; Female; Humans; Nifedipine; Pr | 2007 |
Magnesium sulfate tocolysis: time to quit.
Topics: Female; Humans; Magnesium Sulfate; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnancy Outc | 2007 |
Magnesium sulfate tocolysis: time to quit.
Topics: Female; Humans; Magnesium Sulfate; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnancy Outc | 2007 |
Nifedipine-associated pulmonary complications in pregnancy.
Topics: Adrenal Cortex Hormones; Female; Fetal Membranes, Premature Rupture; Fluid Therapy; Humans; Nifedipi | 2007 |
Nifedipine serum levels in pregnant women undergoing tocolysis with nifedipine.
Topics: Administration, Oral; Chemistry, Pharmaceutical; Cross-Sectional Studies; Female; Gestational Age; H | 2007 |
Feasibility of a randomized controlled trial testing nifedipine vs. placebo for the treatment of preterm labor.
Topics: Cohort Studies; Female; Humans; Infant, Newborn; Multicenter Studies as Topic; Nifedipine; Obstetric | 2007 |
[Indications for respiratory complications during the use of oral nifedipine as a tocolytic agent, especially in patients with multiple pregnancies].
Topics: Adrenal Cortex Hormones; Dyspnea; Female; Humans; Lung; Nifedipine; Obstetric Labor, Premature; Preg | 2007 |
L, P-/Q- and T-type Ca2+ channels in smooth muscle cells from human umbilical artery.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2007 |
Nifedipine (sublingually) in obstetrics: caution for optimal results.
Topics: Administration, Sublingual; Female; Humans; Nifedipine; Obstetric Labor, Premature; Obstetrics; Preg | 2007 |
Severe, early-onset hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome episode with spontaneous remission during pregnancy.
Topics: Adult; Antihypertensive Agents; Female; Fetal Death; HELLP Syndrome; Humans; Methyldopa; Nifedipine; | 2007 |
Successful maternal and fetal outcome in a pregnancy with type V Takayasu's aortoarteritis.
Topics: Adult; Antihypertensive Agents; Arterial Occlusive Diseases; Calcium Channel Blockers; Diuretics; Fe | 2008 |
Calcium-channel blockers: an increasing cause of pulmonary edema during tocolytic therapy.
Topics: Administration, Sublingual; Adult; Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric L | 2008 |
A cost decision analysis of 4 tocolytic drugs.
Topics: Decision Trees; Drug Costs; Female; Humans; Indomethacin; Magnesium Sulfate; Nifedipine; Obstetric L | 2007 |
The relaxant effect of nifedipine in human uterine smooth muscle and the BK(Ca) channel.
Topics: Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Humans; Nifedipine; Obstetric La | 2008 |
Nifedipine concentration in maternal and umbilical cord blood after nifedipine gastrointestinal therapeutic system for tocolysis.
Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Female; Fetal Blood; Half-Life; H | 2008 |
Employing nifedipine as a tocolytic agent prior to external cephalic version.
Topics: Adult; Breech Presentation; Female; Humans; Maternal Age; Nifedipine; Parity; Pregnancy; Preoperativ | 2008 |
[Clinical efficacy of antihypertensive therapy of pregnant women with arterial hypertension with long acting nifedipine and bisoprolol].
Topics: Adrenergic beta-Antagonists; Adult; Bisoprolol; Blood Pressure; Calcium Channel Blockers; Delayed-Ac | 2008 |
A 40-year-old woman with diabetes contemplating pregnancy after gastric bypass surgery.
Topics: Adult; Antihypertensive Agents; Breast Feeding; Diabetes Mellitus, Type 2; Female; Gastric Bypass; G | 2008 |
The management of preterm labour with intact membranes.
Topics: Adrenergic beta-Agonists; Calcium; Ethanol; Extraembryonic Membranes; Female; Fenoterol; Hexoprenali | 1980 |
Binding properties of a novel calcium channel activating dihydropyridine in monolayer cultures of beating myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1984 |
Acute myocardial infarction in a thirty-six year old postpartum female.
Topics: Adult; Aspirin; Digoxin; Electrocardiography; Ergonovine; Female; Heart Aneurysm; Humans; Isosorbide | 1984 |
TTX displacement of [H3]-nitrendipine binding in developing spinal cord neurons.
Topics: Animals; Binding, Competitive; Cells, Cultured; Female; Mice; Neurons; Nifedipine; Nitrendipine; Pre | 1984 |
Effects of nifedipine on human placental arteries.
Topics: Arteries; Chorion; Female; Humans; In Vitro Techniques; Nifedipine; Placenta; Pregnancy; Umbilical A | 1984 |
In vivo chronic lead exposure alters [3H]nitrendipine binding in rat striatum.
Topics: Animals; Corpus Striatum; Female; Lead Poisoning; Nifedipine; Nitrendipine; Pregnancy; Rats; Rats, I | 1984 |
Treatment of normotensive and hypertensive patients with preterm labor using oral nifedipine, a calcium antagonist.
Topics: Adult; Female; Humans; Hypertension; Infant, Newborn; Nifedipine; Obstetric Labor, Premature; Pregna | 1984 |
Interactions between Ca2+-antagonist binding sites in rat adenohypophysis: dependence on estrous cycle.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium; Estrus; Female; Gallopamil; Kinetics; Male; N | 1984 |
Nifedipine.
Topics: Angina Pectoris; Female; Humans; Nifedipine; Pregnancy; Pyridines | 1983 |
Comparison of the effects of nicardipine and nifedipine on isolated human myometrium.
Topics: Adult; Calcium Channel Blockers; Dinoprost; Female; Humans; Myometrium; Nicardipine; Nifedipine; Oxy | 1983 |
Calcium entry blockade as a therapeutic principle in the female urogenital tract.
Topics: Adult; Calcium Channel Blockers; Diflunisal; Dysmenorrhea; Fallopian Tubes; Female; Humans; Labor, O | 1984 |
Treatment of severe pregnancy-associated hypertension with the calcium antagonist nifedipine.
Topics: Adolescent; Adult; Blood Pressure; Female; Humans; Hypertension; Nifedipine; Pilot Projects; Pregnan | 1984 |
Nitrendipine prolongs rat parturition: no changes occur in progesterone withdrawal.
Topics: Animals; Calcium; Female; Labor, Obstetric; Nifedipine; Nitrendipine; Pregnancy; Progesterone; Rats; | 1984 |
Effects of nifedipine on oxytocin- and prostaglandin F2 alpha -induced activity in the postpartum uterus.
Topics: Adult; Dinoprost; Female; Humans; Nifedipine; Oxytocin; Postpartum Period; Pregnancy; Prostaglandins | 1982 |
Deactivation of the uterus during normal and premature labor by the calcium antagonist nicardipine.
Topics: Animals; Calcium Channel Blockers; Female; Labor, Obstetric; Nicardipine; Nifedipine; Obstetric Labo | 1982 |
Effects of nifedipine on spontaneous and methylergometrine-induced activity post partum.
Topics: Adult; Female; Humans; Methylergonovine; Nifedipine; Postpartum Period; Pregnancy; Pyridines; Uterin | 1982 |
Treatment of premature labor with the calcium antagonist nifedipine.
Topics: Adult; Female; Glucocorticoids; Humans; Infant, Newborn; Lung; Nifedipine; Obstetric Labor, Prematur | 1980 |
Effects of nifedipine and Bay K 8644 on myotropic responses in aortic rings of pregnant rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Gestational changes in oxytocin- and endothelin-1-induced contractility of pregnant rat myometrium.
Topics: Animals; Calcium; Endothelins; Escin; Female; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphos | 1995 |
A role for extracellular calcium in the regulation of placental lactogen release by angiotensin-II and dopamine in human term trophoblastic cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1993 |
Stimulation of intracellular calcium concentration by adenosine triphosphate and uridine 5'-triphosphate in human term placental cells: evidence for purinergic receptors.
Topics: Adenosine Triphosphate; Calcium; Calcium Channels; Cells, Cultured; Cobalt; Female; Humans; Ion Chan | 1995 |
Changes in blood velocities of fetal circulation in association with fetal heart rate abnormalities: effect of sublingual administration of nifedipine.
Topics: Administration, Sublingual; Adult; Blood Flow Velocity; Female; Fetal Growth Retardation; Heart Rate | 1995 |
Pregnancy following discontinuation of a calcium channel blocker in the male partner.
Topics: Acrosome; Adult; Chorionic Gonadotropin; Female; Humans; Infertility, Male; Insemination, Artificial | 1995 |
Effect of nifedipine treatment (imprinting) of rat feti and newborns on the responsiveness of adult rat's uterus. Extension of the imprinting theory.
Topics: Animals; Animals, Newborn; Female; Fetus; In Vitro Techniques; Nifedipine; Oxytocin; Pregnancy; Pren | 1995 |
Bradycardia as a presenting feature of late postpartum eclampsia.
Topics: Adult; Bradycardia; Drug Therapy, Combination; Eclampsia; Female; Humans; Magnesium Sulfate; Nifedip | 1994 |
Role of the sodium-calcium exchange mechanism and the effect of magnesium on sodium-free and high-potassium contractures in pregnant human myometrium.
Topics: Calcium-Transporting ATPases; Carrier Proteins; Female; Humans; In Vitro Techniques; Indoles; Isomet | 1995 |
Ritodrine tocolysis and neonatal intraventricular-periventricular hemorrhage.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Female; Humans; Infant, Newborn; Infant, Premature, Diseas | 1995 |
Primary pulmonary hypertension in pregnancy: a case report.
Topics: Adult; Female; Heparin, Low-Molecular-Weight; Humans; Hypertension, Pulmonary; Nifedipine; Pregnancy | 1995 |
The use of nifedipine as first-line hypotensive therapy in gestational hypertension.
Topics: Adult; Female; Gestational Age; Humans; Hypertension; Infant, Newborn; Nifedipine; Pre-Eclampsia; Pr | 1994 |
Atrial natriuretic peptide and cyclic guanosine-3'5'-monophosphate in hypertensive pregnancy and during nifedipine treatment.
Topics: Administration, Oral; Adult; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Female; Humans; | 1994 |
High-voltage-activated calcium current in developing neurons is insensitive to nifedipine.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Cats; Cell Membrane; Chickens; Electric Stimula | 1994 |
Nifedipine reduces pressor responsiveness to angiotensin II in pregnant women.
Topics: Adult; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Nifedipine; Pregnancy; Pregnanc | 1994 |
In vitro comparison of four tocolytic agents, alone and in combination.
Topics: Adult; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; In Vitro Techniq | 1994 |
The influence of tocolytic therapy on serum digoxin-like immunoreactive substance concentration.
Topics: Adult; Blood Proteins; Cardenolides; Digoxin; Female; Humans; Nifedipine; Obstetric Labor, Premature | 1994 |
[Effects of calcium antagonists on prostaglandin E2 production in cultured human amnion cells].
Topics: Amnion; Calcium Channel Blockers; Cells, Cultured; Depression, Chemical; Diltiazem; Dinoprostone; Do | 1994 |
The combination of magnesium sulphate and nifedipine: a cause of neuromuscular blockade.
Topics: Adult; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypertension; Magnesium Sulfate | 1994 |
Severe hypotension and fetal distress following sublingual administration of nifedipine to a patient with severe pregnancy induced hypertension at 33 weeks.
Topics: Adult; Female; Fetal Distress; Humans; Hypertension; Hypotension; Nifedipine; Pregnancy; Pregnancy C | 1993 |
Successful delivery following myocardial ischemia during the second trimester of pregnancy.
Topics: Acute Disease; Adult; Atenolol; Cardiac Catheterization; Coronary Angiography; Female; Heparin; Huma | 1993 |
T-type and L-type calcium currents in freshly dispersed human uterine smooth muscle cells.
Topics: Action Potentials; Biological Transport; Calcium; Cell Membrane; Cells, Cultured; Electrophysiology; | 1993 |
Gestational changes in L-arginine-induced relaxation of pregnant rat and human myometrial smooth muscle.
Topics: Animals; Arginine; Carbachol; Cyclic GMP; Female; Humans; In Vitro Techniques; Muscle, Smooth; Myome | 1993 |
[Endothelin-1-induced contraction of pregnant rat myometrium: role of platelet-activating factor].
Topics: Animals; Dose-Response Relationship, Drug; Endothelins; Female; In Vitro Techniques; Indomethacin; I | 1994 |
Stage-specific effects of cadmium on preimplantation embryo development and implantation in the mouse.
Topics: Animals; Blastomeres; Cadmium; Cells, Cultured; Embryo Transfer; Embryo, Mammalian; Ethylmaleimide; | 1993 |
Stimulatory effect of norepinephrine on progesterone production by human first trimester placenta explants in vitro.
Topics: Atenolol; Clonidine; Culture Media, Serum-Free; Cyclic AMP; Female; Gadolinium; Gonadotropin-Releasi | 1993 |
Nifedipine may cause falsely increased spectrophotometric values of urinary vanillymandelic acid.
Topics: False Positive Reactions; Female; Humans; Nifedipine; Pregnancy; Spectrophotometry; Vanilmandelic Ac | 1993 |
Ca2+ channel blocking activity of lacidipine and amlodipine in A7r5 vascular smooth muscle cells.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cytosol; Dihydropyridines; Female; Fura-2; Muscle, Sm | 1993 |
Myocardial infarction in the third trimester of pregnancy secondary to an aortic valve thrombus.
Topics: Adult; Aortic Valve; Female; Heart Valve Prosthesis; Heparin; Humans; Myocardial Infarction; Nifedip | 1993 |
Successful management of labor and delivery in primary pulmonary hypertension.
Topics: Adenosine; Adult; Delivery, Obstetric; Female; Humans; Hypertension, Pulmonary; Nifedipine; Pregnanc | 1993 |
Use of calcium antagonist (nifedipine) in premature labour.
Topics: Adult; Female; Humans; Isoxsuprine; Nifedipine; Obstetric Labor, Premature; Pregnancy; Tocolysis; Ut | 1993 |
Progesterone and mifepristone modify principally the responses of circular myometrium to oxytocin in preparturient rats: comparison with responses to acetylcholine and to calcium.
Topics: Acetylcholine; Animals; Calcium; Drug Interactions; Female; In Vitro Techniques; Labor, Induced; Mif | 1993 |
Ritodrine and nifedipine as tocolytic agents: a preliminary comparison.
Topics: Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Retrospective Studies; Ritodrine; | 1995 |
Acute myocardial infarction in a healthy mother using bromocriptine for milk suppression.
Topics: Adult; Bromocriptine; Coronary Vasospasm; Dose-Response Relationship, Drug; Female; Humans; Lactatio | 1996 |
Massive vulvar edema complicating tocolysis in a patient with twins. A case report.
Topics: Adult; Betamethasone; Drug Therapy, Combination; Edema; Female; Glucocorticoids; Humans; Infant, New | 1996 |
Endothelin-induced contractions in human placental blood vessels are enhanced in intrauterine growth retardation, and modulated by agents that regulate levels of intracellular calcium.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Primary hyperaldosteronism in pregnancy. A case report.
Topics: Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Combined | 1996 |
Hemodynamic effects of oral nifedipine in preeclamptic hypertensive emergencies.
Topics: Administration, Oral; Adolescent; Adult; Antihypertensive Agents; Blood Pressure; Emergencies; Femal | 1996 |
Effect of the Ca(2+)-channel agonist Bay K 8644 on the contractile responses in human placental veins.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1996 |
Pharmacological characterization of alpha 1-adrenoceptors in porcine uterine artery.
Topics: Animals; Arteries; Calcium; Clonidine; Estrus; Female; In Vitro Techniques; Nifedipine; Norepinephri | 1996 |
Characterization of a chemical anoxia model in cerebellar granule neurons using sodium azide: protection by nifedipine and MK-801.
Topics: Animals; Azides; Brain Ischemia; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Dose-Response Rel | 1996 |
Characterization of endothelin receptors in the human umbilical artery and vein.
Topics: Adult; Binding, Competitive; Calcium Channel Blockers; Endothelin Receptor Antagonists; Endothelin-1 | 1996 |
Pharmacological characterisation of voltage-sensitive calcium channels and neurotransmitter release from mouse cerebellar granule cells in culture.
Topics: Animals; Aspartic Acid; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cerebellum; Dos | 1997 |
Effect of nifedipine on fetal and maternal hemodynamics and blood gases in the pregnant ewe.
Topics: Acidosis; Animals; Bicarbonates; Female; Fetal Blood; Fetal Diseases; Fetus; Half-Life; Hemodynamics | 1997 |
Heterogeneity and complexity of alpha 1-adrenoceptors in the ovine uterine artery and umbilical vein.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Binding, Competitive; Ca | 1997 |
The effect of nifedipine and methyldopa on maternal cerebral circulation.
Topics: Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Cerebral Arteries; Cerebrovascular Cir | 1997 |
24-hour blood pressure monitoring to evaluate the effects of nifedipine in pre-eclampsia and in chronic hypertension in pregnancy.
Topics: Adult; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chronic Dise | 1997 |
Withdrawal of nifedipine capsules: jeopardizing the treatment of acute severe hypertension in pregnancy? Australasian Society for the Study of Hypertension in Pregnancy.
Topics: Antihypertensive Agents; Australia; Female; Humans; Legislation, Drug; Nifedipine; Pre-Eclampsia; Pr | 1997 |
Effects of cGMP and the nitric oxide donors glyceryl trinitrate and sodium nitroprusside on contractions in vitro of isolated myometrial tissue from pregnant women.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Benzopyrans; Calcium Channel Agonists; Calcium Channel Block | 1997 |
Variations between family physicians and obstetricians in the evaluation and treatment of preterm labor.
Topics: Adrenergic beta-Agonists; Adult; Family Practice; Female; Humans; Male; Middle Aged; Nifedipine; Obs | 1997 |
Calcium-channel blockers in the management of preterm labour.
Topics: Calcium Channel Blockers; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Ritodri | 1997 |
[The effect of nifedipine on the microcirculation in pregnancy-induced hypertension].
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Female; Humans; Microcirculation; Nails; Nifedipine | 1996 |
Nifedipine and ritodrine in the management of preterm labor: a randomized multicenter trial.
Topics: Bias; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Research Design; Ritodrine; | 1997 |
Sublingual nifedipine in human pregnancy.
Topics: Administration, Sublingual; Apgar Score; Birth Weight; Calcium Channel Blockers; Female; Humans; Hyp | 1997 |
Effect of calcium ion channel antagonists on chorionic gonadotropin secretion.
Topics: Calcium Channel Blockers; Calcium Radioisotopes; Chorionic Gonadotropin; Female; Gonadotropin-Releas | 1997 |
Withdrawal of nifedipine capsules: jeopardising the treatment of acute severe hypertension in pregnancy?
Topics: Acute Disease; Australia; Calcium Channel Blockers; Contraindications; Drug Labeling; Female; Humans | 1998 |
Withdrawal of nifedipine capsules: jeopardising the treatment of acute severe hypertension in pregnancy?
Topics: Acute Disease; Administration, Oral; Administration, Sublingual; Blood Pressure; Calcium Channel Blo | 1998 |
Withdrawal of nifedipine capsules: jeopardising the treatment of acute severe hypertension in pregnancy?
Topics: Acute Disease; Administration, Oral; Australia; Blood Pressure; Calcium Channel Blockers; Capsules; | 1998 |
Pregnancy-induced hypertension, antihypertensive drugs and the development of fetal behavioural states.
Topics: Antihypertensive Agents; Cohort Studies; Embryo, Mammalian; Embryonic and Fetal Development; Female; | 1998 |
Calcium current activated by potassium ions in voltage-clamped rat hippocampal pyramidal neurones.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Barium Compounds; Cadmiu | 1998 |
Differences in the effects of vasopressin and oxytocin on feline gastric corpus motility: selective action of vasopressin on longitudinal muscle.
Topics: Animals; Atropine; Cats; Female; In Vitro Techniques; Male; Muscle Contraction; Nifedipine; Oxytocin | 1998 |
Magnesium sulfate as an anticonvulsant in eclampsia.
Topics: Adolescent; Adult; Anticonvulsants; Birth Weight; Delivery, Obstetric; Eclampsia; Female; Humans; Ma | 1995 |
Hyperpolarization and slowing of the rate of contraction in human uterus in pregnancy by prostaglandins E2 and f2alpha: involvement of the Na+ pump.
Topics: Albuterol; Calcium; Calcium Channel Blockers; Charybdotoxin; Cyclic AMP; Dinoprost; Dinoprostone; En | 1999 |
Myocardial infarction during nifedipine therapy for preterm labor.
Topics: Adult; Calcium Channel Blockers; Female; Humans; Myocardial Infarction; Nifedipine; Obstetric Labor, | 1999 |
Pulmonary hypertension in pregnancy: treatment with pulmonary vasodilators.
Topics: Adult; Antihypertensive Agents; Epoprostenol; Female; Humans; Hypertension, Pulmonary; Nifedipine; P | 1999 |
Management of preterm labour. Nifedipine in management of preterm labour is safe.
Topics: Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Tocolytic Agents | 1999 |
Symptomatic hypocalcaemia in hypermagnesaemia-induced hypoparathyroidism, during magnesium tocolytic therapy--possible involvement of the calcium-sensing receptor.
Topics: Adult; Calcium; Female; Humans; Hypocalcemia; Hypoparathyroidism; Indomethacin; Magnesium; Nifedipin | 1999 |
Antihypertensive treatment in early postnatal life modulates prenatal dietary influences upon blood pressure in the rat.
Topics: Analysis of Variance; Angiotensin Receptor Antagonists; Animal Nutritional Physiological Phenomena; | 2000 |
Changes in the mechanisms involved in uterine contractions during pregnancy in guinea-pigs.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Endoplasmic Reticulum; Female; | 2000 |
Nifedipine in pregnancy.
Topics: Drug Interactions; Female; Humans; Hypertension; Nifedipine; Pregnancy; Pregnancy Complications, Car | 2000 |
Functional alteration of dihydropyridine-sensitive Ca(2+) channels in the adrenal glomerulosa of pregnant rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2000 |
Potassium depolarization-induced cAMP stimulates somatostatin mRNA levels in cultured diencephalic neurons.
Topics: Animals; Calcium; Calcium Channels, L-Type; Calcium Signaling; Cell Membrane; Cells, Cultured; Cycli | 2000 |
Nifedipine versus ritodrine for suppression of preterm labor; a meta-analysis.
Topics: Female; Humans; Meta-Analysis as Topic; Nifedipine; Obstetric Labor, Premature; Pregnancy; Reproduci | 2000 |
Nifedipine as a safe and effective tocolytic agent in the treatment of preterm labor.
Topics: Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Tocolytic Agents | 2000 |
Expectant management of early onset, severe pre-eclampsia: maternal outcome.
Topics: Adolescent; Adult; Antihypertensive Agents; Calcium Channel Blockers; Dihydralazine; Female; Fetal D | 2000 |
Expectant management of early onset, severe pre-eclampsia: perinatal outcome.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Female; Fetal Monitoring; Humans; Infant Mortalit | 2000 |
Vasopressin-induced neurotrophism in cultured neurons of the cerebral cortex: dependency on calcium signaling and protein kinase C activity.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine Vasopressin; Calcium Channels, L-Type; Cal | 2000 |
Search for best tocolytic for preterm labour.
Topics: Female; Humans; Indomethacin; Nifedipine; Obstetric Labor, Premature; Pregnancy; Randomized Controll | 2000 |
[Hypertensive crisis, hypertensive emergency. Nitrate spray and ambulance--this can also be wrong].
Topics: Administration, Oral; Aerosols; Ambulances; Emergencies; Female; Humans; Hypertension, Malignant; Ni | 2001 |
Factor analysis, including antihypertensive medication, of the outcome of pregnancy in pregnancy-associated hypertension.
Topics: Antihypertensive Agents; Apgar Score; Cesarean Section; Comorbidity; Disease Susceptibility; Female; | 2001 |
Calcium and pituitary adenylate cyclase-activating polypeptide induced expression of circadian clock gene mPer1 in the mouse cerebellar granule cell culture.
Topics: Animals; Biological Clocks; Bucladesine; Butadienes; Calcium; Calcium Channel Blockers; Calcium-Calm | 2001 |
[Analysis of inductive factors, diagnosis and treatment of 21 cases with pregnancy accompanied with pulmonary edema].
Topics: Adult; Female; Humans; Nifedipine; Pregnancy; Pregnancy Complications; Pulmonary Edema; Risk Factors | 2001 |
Calcium channels contribute to the decrease in blood pressure of pregnant rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2002 |
Expression and modulation of Rho kinase in human pregnant myometrium.
Topics: Adult; Amides; Calcium Channel Blockers; Enzyme Inhibitors; Female; Gene Expression; Humans; Intrace | 2002 |
Tocolysis with nifedipine or beta-adrenergic agonists: a meta-analysis.
Topics: Adrenergic beta-Agonists; Female; Humans; Meta-Analysis as Topic; Nifedipine; Obstetric Labor, Prema | 2002 |
Enhanced vascular effects of the Ca(2+) channel agonist Bay K 8644 in pregnant rabbits.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2002 |
Investigations into the mechanisms controlling prostaglandin production by the guinea-pig placenta: roles of calcium and gonadotrophin-releasing hormone.
Topics: Animals; Calcium; Calcium Channel Blockers; Egtazic Acid; Female; Gonadotropin-Releasing Hormone; Gu | 2002 |
Short therapeutic window for nifedipine in transient intrauterine ischemia in fetal rat brain.
Topics: Animals; Brain; Brain Ischemia; Female; Fetus; Mitochondria; Nifedipine; Oxygen Consumption; Pregnan | 2002 |
Inhibition of prostaglandin-induced uterine activity by nifedipine.
Topics: Abortion, Therapeutic; Adolescent; Adult; Female; Humans; Nifedipine; Pregnancy; Prostaglandins; Pro | 1979 |
Inhibition of myometrial hyperactivity by calcium antagonists.
Topics: Animals; Calcium; Female; Humans; Nifedipine; Pregnancy; Pyridines; Uterine Contraction | 1979 |
Relaxant effects of nifedipine on isolated, human myometrium.
Topics: Adult; Female; Humans; Middle Aged; Muscle Contraction; Muscle Relaxation; Myometrium; Nifedipine; O | 1979 |
[Hemodynamic effects of antihypertensive drugs on pregnancy-induced hypertension].
Topics: Antihypertensive Agents; Female; Hemodynamics; Humans; Nifedipine; Pre-Eclampsia; Pregnancy | 1992 |
Fast Na+ channels in smooth muscle from pregnant rat uterus.
Topics: Animals; Calcium Channels; Female; In Vitro Techniques; Isoproterenol; Magnesium; Muscle, Smooth, Va | 1992 |
Nifedipine treatment in preeclampsia reverts the increased erythrocyte aggregation to normal.
Topics: Erythrocyte Aggregation; Female; Humans; Nifedipine; Pre-Eclampsia; Pregnancy; Reference Values | 1992 |
Ca2+ transport through the brush border membrane of human placenta syncytiotrophoblasts.
Topics: Adenosine Triphosphate; Biological Transport; Calcium; Calcium Radioisotopes; Calcium-Binding Protei | 1992 |
Nifedipine for treatment of preterm labor: a historic prospective study.
Topics: Embryonic and Fetal Development; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; | 1992 |
Effects of nifedipine on placental blood flow, placental weight and fetal weight in normotensive and spontaneously hypertensive rats.
Topics: Animals; Female; Fetus; Nifedipine; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy, Animal; Rats; Rat | 1992 |
Hepatotoxicity with the administration of nifedipine for treatment of preterm labor.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Female; Humans; Infusion Pumps; Liver; Mag | 1992 |
The effect of nifedipine and dipyridamole on the Doppler blood flow waveforms of umbilical and uterine arteries in hypertensive pregnant women.
Topics: Adult; Arteries; Blood Flow Velocity; Dipyridamole; Female; Humans; Hypertension; Nifedipine; Pregna | 1992 |
The effects of nifedipine on pregnancy outcome and morphology of the placenta, uterus, and cervix during late pregnancy in the rat.
Topics: Animals; Body Weight; Cervix Uteri; Collagen; Dose-Response Relationship, Drug; Female; Nifedipine; | 1992 |
A case of nephrotic syndrome and renal dysfunction in a pregnant woman with diabetes mellitus.
Topics: Adult; Basement Membrane; Biopsy; Calcium Channel Blockers; Capillaries; Diabetic Nephropathies; End | 1992 |
Oral nifedipine pharmacokinetics in pregnancy-induced hypertension.
Topics: Administration, Oral; Adult; Female; Half-Life; Humans; Hypertension; Metabolic Clearance Rate; Nife | 1992 |
Ability of nifedipine to prolong parturition in rats.
Topics: Animals; Dose-Response Relationship, Drug; Female; Fetal Death; Labor, Obstetric; Nifedipine; Pregna | 1992 |
Identical phalangeal defects induced by phenytoin and nifedipine suggest fetal hypoxia and vascular disruption behind phenytoin teratogenicity.
Topics: Abnormalities, Drug-Induced; Animals; Blood Vessels; Female; Fetal Hypoxia; Gestational Age; Heart R | 1992 |
Effects of Ca2+ antagonists nifedipine and diltiazem on isolated human chorionic arteries and veins.
Topics: Arteries; Calcium; Calcium Radioisotopes; Diltiazem; Female; Humans; In Vitro Techniques; Ketanserin | 1990 |
The redistribution of the blood flow under nifedipine treatment in the sheep foetuses.
Topics: Animals; Atropine; Blood Pressure; Female; Fetus; Heart Rate, Fetal; Nifedipine; Pregnancy; Proprano | 1991 |
Electrophysiological properties of membrane currents in single myometrial cells isolated from pregnant rats.
Topics: Animals; Cell Separation; Electrophysiology; Female; Membrane Potentials; Myometrium; Nifedipine; Pr | 1991 |
Effects of nifedipine on normotensive rat placental blood flow, placental weight and fetal weight.
Topics: Animals; Birth Weight; Blood Flow Velocity; Drug Evaluation, Preclinical; Electrolysis; Female; Fetu | 1991 |
Nifedipine concentrations in maternal and umbilical serum, amniotic fluid, breast milk and urine of mothers and offspring.
Topics: Administration, Oral; Adult; Amniotic Fluid; Female; Fetal Blood; Humans; Hypertension; Maternal-Fet | 1991 |
[Effect of nifedipine on fetal heart rate in pre-eclamptic patients].
Topics: Adolescent; Adult; Female; Heart Rate, Fetal; Humans; Nifedipine; Pre-Eclampsia; Pregnancy | 1991 |
Effects of bupivacaine and calcium antagonists on human uterine arteries in pregnant and non-pregnant women.
Topics: Arteries; Bupivacaine; Female; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vasc | 1991 |
Nifedipine increases urinary excretion of prostacyclin metabolite in hypertensive pregnancy.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Blood Pressure; Catecholamines; Creatinine; Dinoprostone; Epopr | 1991 |
Nifedipine pharmacokinetics and pharmacodynamics during the immediate postpartum period in patients with preeclampsia.
Topics: Administration, Oral; Female; Half-Life; Humans; Nifedipine; Postpartum Period; Pre-Eclampsia; Pregn | 1991 |
Long term treatment with nifedipine retard to suppress preterm labour.
Topics: Adult; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Tocolysis | 1991 |
Blood pressure, plasma renin activity and calcium metabolism in hypertensive pregnancy: the effect of nifedipine.
Topics: Adult; Blood Pressure; Calcium; Electrolytes; Female; Humans; Hypertension; Nifedipine; Pregnancy; P | 1990 |
Tocolytic agents act on calcium channel current in single smooth muscle cells of pregnant rat uterus.
Topics: Animals; Calcium Channels; Electrophysiology; Evoked Potentials; Female; Isoproterenol; Magnesium; M | 1990 |
Effect of nifedipine in arterial vasculature of human placenta.
Topics: Arteries; Calcium Channels; Female; Humans; In Vitro Techniques; Isometric Contraction; Muscle Contr | 1990 |
Uterine and fetal flow velocity waveforms in hypertensive pregnancy: the effect of a single dose of nifedipine.
Topics: Adult; Apgar Score; Birth Weight; Blood Flow Velocity; Cerebral Arteries; Cesarean Section; Female; | 1990 |
Single dose of nifedipine in normotensive pregnancy: nifedipine concentrations, hemodynamic responses, and uterine and fetal flow velocity waveforms.
Topics: Adult; Blood Flow Velocity; Drug Evaluation; Female; Fetal Blood; Heart Rate, Fetal; Hemodynamics; H | 1990 |
Vasodilatory effects of nifedipine, methoxyverapamil, and sodium nitroprusside on contractile responses of the ewe uterine artery at term pregnancy.
Topics: Animals; Arteries; Female; Gallopamil; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nit | 1990 |
The effect of nifedipine therapy on fetal and placental Doppler waveforms in preeclampsia remote from term.
Topics: Administration, Oral; Adolescent; Adult; Aorta; Blood Pressure; Carotid Artery, Internal; Female; Fe | 1990 |
Magnesium plus nifedipine.
Topics: Blood Pressure; Drug Interactions; Female; Humans; Magnesium; Nifedipine; Pre-Eclampsia; Pregnancy | 1990 |
Successful pregnancy in a woman with systemic sclerosis while taking nifedipine.
Topics: Adult; Female; Foot Diseases; Humans; Infant, Newborn; Infertility, Female; Male; Nifedipine; Pregna | 1990 |
Histological and in vitro studies supporting decreased uteroplacental blood flow as explanation for digital defects after administration of vasodilators.
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Extremities; Felodipine; Female; In Vitro Techni | 1990 |
Transport of calcium across the dually perfused placenta of the rat.
Topics: Animals; Barium; Binding, Competitive; Biological Transport, Active; Cadmium; Calcium; Female; Gluco | 1990 |
Effect of nifedipine on fetal heart rate in the treatment of severe pregnancy-induced hypertension.
Topics: Female; Heart Rate, Fetal; Humans; Hypertension; Nifedipine; Pregnancy; Pregnancy Complications, Car | 1990 |
Effect of some drugs on thromboplastin activity in mouse trophoblast cells in vitro and in vivo.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Animals; Calcium Channel Blockers; Dinoprostone; Fe | 1986 |
Inhibition of the oxygen-induced contraction of the isolated human umbilical artery by indomethacin, flurbiprofen, aspirin and drugs modifying Ca2+ disposition.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1988 |
A preliminary study on the effect of induced hypocalcaemia and nifedipine on uterine activity in the parturient cow.
Topics: Animals; Calcium; Cattle; Cattle Diseases; Edetic Acid; Female; Hypocalcemia; Labor, Obstetric; Nife | 1989 |
Effect of nifedipine on Doppler flow velocity waveforms in severe pre-eclampsia.
Topics: Adult; Blood Flow Velocity; Female; Humans; Nifedipine; Placenta; Pre-Eclampsia; Pregnancy; Ultrason | 1989 |
Characterization of membrane calcium channels in nonpregnant and pregnant human uterus.
Topics: Adult; Binding Sites; Calcium Channels; Cell Membrane; Female; Humans; Middle Aged; Myometrium; Nica | 1989 |
Nifedipine pharmacokinetics during preterm labor tocolysis.
Topics: Adult; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Tocolysis; Tocolytic Agent | 1989 |
Physiological aspects of pregnancy and parturition in dogs.
Topics: Animals; Animals, Newborn; Body Temperature; Dogs; Electromyography; Estradiol; Female; Labor, Obste | 1989 |
Doppler assessment of the fetal and uteroplacental circulation during nifedipine therapy for preterm labor.
Topics: Adolescent; Adult; Blood Circulation; Blood Flow Velocity; Female; Fetal Monitoring; Fetus; Humans; | 1989 |
Effects of calcium antagonists during pregnancy.
Topics: Animals; Calcium Channel Blockers; Female; Hemodynamics; Nifedipine; Pregnancy; Pregnancy, Animal; R | 1989 |
Neonatal bilirubin production after preterm labor tocolysis with nifedipine.
Topics: Bilirubin; Blood Glucose; Carboxyhemoglobin; Female; Gestational Age; Humans; Infant, Newborn; Nifed | 1989 |
Neuromuscular blockade with magnesium sulfate and nifedipine.
Topics: Adult; Drug Interactions; Female; Humans; Magnesium Sulfate; Neuromuscular Diseases; Neuromuscular J | 1989 |
Fetal cardiovascular effects of nifedipine in rats.
Topics: Animals; Cardiovascular System; Dose-Response Relationship, Drug; Female; Fetus; Heart Failure; Nife | 1989 |
[Therapy of the hypertensive crisis].
Topics: Administration, Oral; Adrenergic beta-Antagonists; Calcium Channel Blockers; Clonidine; Dihydralazin | 1985 |
The effect of a calcium antagonist, nitrendipine, on the responses of isolated strips of human, chorionic plate artery to prostaglandins E2 and E1.
Topics: Alprostadil; Arteries; Calcium Channel Blockers; Cesarean Section; Chorion; Dinoprostone; Female; Hu | 1985 |
Pharmacologic levels of nitrendipine do not affect actin-myosin interaction in the human uterus and placenta.
Topics: Actins; Actomyosin; Adenosine Triphosphatases; Adenosine Triphosphate; Calcium Channel Blockers; Fem | 1986 |
Regional modification of brain calcium antagonist binding after in vivo chronic lead exposure.
Topics: Animals; Binding Sites; Brain; Calcium; Drug Interactions; Female; Lead; Maternal-Fetal Exchange; Ni | 1986 |
Synthesis of carboxy-nifedipine and its use in the preparation of an affinity resin for the 1,4-dihydropyridine receptor.
Topics: Animals; Calcium Channels; Chromatography, Affinity; Female; Membranes; Muscle Proteins; Muscles; Ni | 1986 |
Preeclampsia: platelets and antiplatelet therapy.
Topics: Aspirin; Blood Coagulation; Blood Platelets; Diagnosis, Differential; Female; Fetus; Humans; Hyperte | 1988 |
[The tocolytic action of nifedipine, a calcium antagonist].
Topics: Drug Evaluation; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy; Pregnancy Trimes | 1987 |
[3H]-Nitrendipine binding in developing dissociated fetal mouse spinal cord neurons.
Topics: Animals; Female; Kinetics; Mice; Neurons; Nifedipine; Nitrendipine; Pregnancy; Spinal Cord; Time Fac | 1985 |
The influence of oestrogen and progesterone on the actions of two calcium entry blockers in the rat uterus.
Topics: Animals; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Female; Nifedipi | 1988 |
Pharmacokinetics of nisoldipine. II. Distribution to and elimination from tissues and organs following single or repeated administration of [14C]nisoldipine to rats and dogs.
Topics: Administration, Oral; Animals; Autoradiography; Calcium Channel Blockers; Dogs; Female; Injections, | 1988 |
Effects of calcium channel-blocker tokolysis on the foetal circulation.
Topics: Animals; Atropine Derivatives; Blood Circulation; Blood Pressure; Female; Fetal Heart; Fetus; Heart | 1988 |
Cardiorespiratory effects of nifedipine in pregnant sheep.
Topics: Animals; Blood Pressure; Electromyography; Female; Fetus; Heart Rate; Muscle, Smooth; Nifedipine; Pr | 1988 |
Nifedipine does not adversely affect uteroplacental blood flow in the hypertensive term-pregnant rat.
Topics: Animals; Female; Hemodynamics; Hypertension; Nifedipine; Placenta; Pregnancy; Pregnancy Complication | 1988 |
Nifedipine kinetics in the rat and relationship between its serum concentrations and uterine and cardiovascular effects.
Topics: Animals; Chromatography, High Pressure Liquid; Female; Hemodynamics; Infusions, Intravenous; Nifedip | 1988 |
Nephrolithiasis following in utero diuretic exposure: an unusual case.
Topics: Ethacrynic Acid; Female; Humans; Infant, Newborn; Kidney Calculi; Nifedipine; Polyhydramnios; Pregna | 1988 |
Hyperphalangeal bones induced in rat pups by maternal treatment with nifedipine.
Topics: Abnormalities, Drug-Induced; Animals; Female; Forelimb; Gestational Age; Maternal-Fetal Exchange; Ni | 1988 |
Nifedipine and platelets in preeclampsia.
Topics: Blood Pressure; Female; Humans; Nifedipine; Platelet Count; Pre-Eclampsia; Pregnancy; Time Factors | 1988 |
Magnesium plus nifedipine: potentiation of hypotensive effect in preeclampsia?
Topics: Adult; Drug Synergism; Female; Humans; Hypertension; Magnesium Sulfate; Methyldopa; Nifedipine; Pre- | 1988 |
Nifedipine as a second line antihypertensive drug in pregnancy.
Topics: Adult; Atenolol; Delayed-Action Preparations; Drug Therapy, Combination; Female; Humans; Hypertensio | 1987 |
[Noninvasive evaluation of the effectiveness of the treatment of primary pulmonary hypertension. Case report].
Topics: Adult; Blood Pressure; Echocardiography; Female; Humans; Hypertension, Pulmonary; Nifedipine; Pregna | 1987 |
[Essential and iatrogenic gingival hyperplasia. Its morphology and significance].
Topics: Adolescent; Adult; Chronic Disease; Cyclosporins; Female; Gingiva; Gingival Hyperplasia; Gingivectom | 1986 |
The use of a calcium agonist (nifedipine) to suppress preterm labor.
Topics: Ethics, Medical; Female; Humans; Nifedipine; Obstetric Labor, Premature; Pregnancy | 1987 |
The effects of aminophylline and nifedipine on contractility of isolated pregnant human myometrium.
Topics: Aminophylline; Cesarean Section; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniqu | 1987 |
Nifedipine: effects on fetal and maternal hemodynamics in pregnant sheep.
Topics: Animals; Female; Fetus; Hemodynamics; Nifedipine; Oxygen Consumption; Pregnancy; Pregnancy, Animal; | 1987 |
The effect of a calcium channel blocker (nifedipine) on uterine blood flow in the pregnant goat.
Topics: Animals; Blood Pressure; Female; Goats; Heart Rate; Nifedipine; Pregnancy; Pregnancy, Animal; Region | 1986 |
Comparison of nifedipine and diltiazem with salbutamol for prevention of preterm delivery in the ovariectomized, oestrogen-treated late pregnant rat.
Topics: Albuterol; Animals; Benzazepines; Diltiazem; Female; Fetal Death; Nifedipine; Obstetric Labor, Prema | 1986 |
The effects of long-term infusion of salbutamol, diltiazem and nifedipine on uterine contractions in the ovariectomized, post-partum rat.
Topics: Albuterol; Animals; Benzazepines; Diltiazem; Female; Nifedipine; Ovariectomy; Postpartum Period; Pre | 1986 |
Nifedipine or verapamil counteracts hypertension in gravid ewes.
Topics: Animals; Blood Gas Analysis; Female; Hypertension; Nifedipine; Norepinephrine; Pre-Eclampsia; Pregna | 1986 |
In vitro effects of calcium entry blockers, chlorpromazine and fenoterol upon human pregnant myometrium contractility.
Topics: Adult; Calcium Channel Blockers; Chlorpromazine; Cinnarizine; Female; Fenoterol; Humans; In Vitro Te | 1986 |
Effect of nicardipine HCl on prematurely induced uterine activity in the pregnant rabbit.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Electromyograph | 1985 |
Tocolytic and hemodynamic effects of nifedipine in the ewe.
Topics: Animals; Blood Pressure; Female; Fetal Heart; Heart Rate; Hemodynamics; Infusions, Parenteral; Labor | 1985 |
The management of preterm labor with the calcium channel-blocking agent nifedipine combined with the beta-mimetic terbutaline.
Topics: Adult; Calcium; Drug Therapy, Combination; Female; Fenoterol; Humans; Myometrium; Nifedipine; Obstet | 1985 |
The potencies and selectivities of four calcium antagonists as inhibitors of uterine contractions in the rat in vivo.
Topics: Albuterol; Animals; Blood Pressure; Calcium Channel Blockers; Castration; Diltiazem; Female; Gallopa | 1985 |
[Hypertensive crisis during E.P.H. gestosis treated with sublingual nifedipine. Report of a case].
Topics: Administration, Oral; Adolescent; Female; Humans; Hypertension; Nifedipine; Pre-Eclampsia; Pregnancy | 1985 |