Page last updated: 2024-11-01

nifedipine and Porphyrias

nifedipine has been researched along with Porphyrias in 2 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.

Research Excerpts

ExcerptRelevanceReference
"Acute intermittent porphyria (AIP) is a rare metabolic disorder of heme biosynthesis characterized by enzymatic defect of porphobiligen desaminase with accumulation and increased excretion of porphyrins and their precursors."7.75[Neurological complications of acute intermittent porphyria precipitated by porphyrinogenic drugs and efficiency of heme-arginate treatment]. ( Akopova-Larbi, R; Ben Youssef, TI; Gargouri, A; Gouider, R; Gouider-Khouja, N; Kraoua, I, 2009)
"Acute intermittent porphyria (AIP) is a rare metabolic disorder of heme biosynthesis characterized by enzymatic defect of porphobiligen desaminase with accumulation and increased excretion of porphyrins and their precursors."3.75[Neurological complications of acute intermittent porphyria precipitated by porphyrinogenic drugs and efficiency of heme-arginate treatment]. ( Akopova-Larbi, R; Ben Youssef, TI; Gargouri, A; Gouider, R; Gouider-Khouja, N; Kraoua, I, 2009)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akopova-Larbi, R1
Ben Youssef, TI1
Gargouri, A1
Kraoua, I1
Gouider, R1
Gouider-Khouja, N1
Bhadoria, DP1
Srivastava, AK1
Sharma, M1
Deswal, A1
Bhadoria, P1
Malhotra, KK1

Other Studies

2 other studies available for nifedipine and Porphyrias

ArticleYear
[Neurological complications of acute intermittent porphyria precipitated by porphyrinogenic drugs and efficiency of heme-arginate treatment].
    La Tunisie medicale, 2009, Volume: 87, Issue:9

    Topics: Acute Disease; Adolescent; Arginine; Electromyography; Famotidine; Female; Heme; Heme Oxygenase (Dec

2009
Safe use of clonidine, nifedipine and vitamin K in hepatic porphyria.
    The Journal of the Association of Physicians of India, 1988, Volume: 36, Issue:11

    Topics: Adult; Clonidine; Humans; Hypertension; Liver Diseases; Male; Nifedipine; Porphyrias; Vitamin K

1988