nifedipine has been researched along with Pheochromocytoma in 43 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
Excerpt | Relevance | Reference |
---|---|---|
"Two patients with pheochromocytoma initially responded to oral or sublingual nifedipine with marked reduction in systolic blood pressure (range 50-160 mmHg) without concomitant increment in the heart rate or clinical consequences." | 7.68 | Precipitous hypotension after nifedipine in pheochromocytoma: report of 2 cases. ( Rujiwanichkul, K; Tantawanichpisal, D; Yipintsoi, T, 1993) |
"In the present study, we report a case of pheochromocytoma whose high blood pressure was well controlled by single-agent therapy with long-acting nifedipine, in spite of the failure of the combination of labetalol and prazosin in lowering blood pressure satisfactorily." | 7.67 | Effectiveness of long-acting nifedipine in pheochromocytoma. ( Fujiwara, R; Kutsumi, Y; Miyabo, S; Nakai, T; Takahashi, S; Tamai, T, 1989) |
"Maitotoxin (MTX) induced exocytotic secretion of ATP from PC12 rat pheochromocytoma cells." | 7.67 | Differential effects of maitotoxin on ATP secretion and on phosphoinositide breakdown in rat pheochromocytoma cells. ( Daly, JW; Gusovsky, F; Rojas, E; Yasumoto, T, 1988) |
"Labile high blood pressure and associated complaints (eg, severe headache, palpitation, and vague discomfort in the chest) in a 28-year-old woman with pheochromocytoma were stabilized by adding nifedipine to the conventional regimen of alpha- and beta-blocking agents." | 7.67 | Preoperative management of pheochromocytoma with the calcium-antagonist nifedipine. ( Chimori, K; Miura, K; Miyazaki, S; Nakajima, T, 1985) |
"Bradykinin treatment produced a significant incorporation of [32P]-phosphate into two phosphopeptides of tryptically digested tyrosine hydroxylase." | 5.28 | Regulation of tyrosine hydroxylase activity in pheochromocytoma PC-12 cells by bradykinin. ( Bowyer, JF; Houchi, H; Masserano, JM; Weiner, N, 1990) |
"A 13-year-old girl with right adrenal pheochromocytoma pretreated with Nifedipine, underwent surgical removal of the tumor." | 3.81 | MANAGEMENT OF PHEOCHROMOCYTOMA IN THE ABSENCE OF ALPHA BLOKERS: A CASE REPORT FROM AYDER REFERRAL HOSPITAL. ( Mengesha, RE; Rother, RB, 2015) |
"Two patients with pheochromocytoma initially responded to oral or sublingual nifedipine with marked reduction in systolic blood pressure (range 50-160 mmHg) without concomitant increment in the heart rate or clinical consequences." | 3.68 | Precipitous hypotension after nifedipine in pheochromocytoma: report of 2 cases. ( Rujiwanichkul, K; Tantawanichpisal, D; Yipintsoi, T, 1993) |
"Maitotoxin (MTX) activates calcium channels and stimulates phosphoinositide breakdown in pheochromocytoma PC12 cells, while having no effect on basal levels of the cyclic nucleotides cAMP and cGMP." | 3.68 | Effects of maitotoxin on atrial natriuretic factor-mediated accumulation of cyclic GMP in PC12 cells. ( Daly, JW; Gusovsky, F; Schulick, A; Yasumoto, T, 1990) |
"BAY K 8644, a drug that elicits calcium-dependent muscle contraction, inhibits binding of the voltage-dependent calcium channel antagonist [3H]nitrendipine to brain and PC12 pheochromocytoma cell membranes." | 3.67 | Calcium channel 'agonist' BAY K 8644 inhibits calcium antagonist binding to brain and PC12 cell membranes. ( Carpenter, CL; Cooper, EC; Greenberg, DA, 1984) |
"The inhibitory effect of nicardipine, a potent Ca2+ channel blocker in muscular cells, on the Ca2+ channel of clonal rat pheochromocytoma cells (PC12h) and cultured rat adrenal medullary cells was studied during the neuronal differentiation mediated by nerve growth factor (NGF)." | 3.67 | Neuronal differentiation of Ca2+ channel by nerve growth factor. ( Hatanaka, H; Takahashi, M; Tsukui, H, 1985) |
"The mechanism of calcium channel antagonism by phenytoin was studied by comparing the effects of phenytoin and classical calcium channel antagonists on K+-stimulated 45Ca uptake and [3H]nitrendipine binding in the PC12 pheochromocytoma cell line." | 3.67 | Mechanism of calcium channel inhibition by phenytoin: comparison with classical calcium channel antagonists. ( Carpenter, CL; Greenberg, DA; Messing, RO, 1985) |
"In the present study, we report a case of pheochromocytoma whose high blood pressure was well controlled by single-agent therapy with long-acting nifedipine, in spite of the failure of the combination of labetalol and prazosin in lowering blood pressure satisfactorily." | 3.67 | Effectiveness of long-acting nifedipine in pheochromocytoma. ( Fujiwara, R; Kutsumi, Y; Miyabo, S; Nakai, T; Takahashi, S; Tamai, T, 1989) |
"Maitotoxin (MTX) induced exocytotic secretion of ATP from PC12 rat pheochromocytoma cells." | 3.67 | Differential effects of maitotoxin on ATP secretion and on phosphoinositide breakdown in rat pheochromocytoma cells. ( Daly, JW; Gusovsky, F; Rojas, E; Yasumoto, T, 1988) |
"Nifedipine, a calcium-antagonist and potent vasodilator, was tested in three patients with pheochromocytoma." | 3.67 | Calcium-channel inhibition in pheochromocytoma. ( Fathi, M; Favre, L; Forster, A; Vallotton, MB, 1986) |
"Labile high blood pressure and associated complaints (eg, severe headache, palpitation, and vague discomfort in the chest) in a 28-year-old woman with pheochromocytoma were stabilized by adding nifedipine to the conventional regimen of alpha- and beta-blocking agents." | 3.67 | Preoperative management of pheochromocytoma with the calcium-antagonist nifedipine. ( Chimori, K; Miura, K; Miyazaki, S; Nakajima, T, 1985) |
"PC12 cells, a clonal rat pheochromocytoma cell line, possess voltage-dependent calcium channels that bind the high affinity dihydropyridine calcium antagonist [3H]nitrendipine and other calcium channel blockers." | 3.66 | Calcium antagonists High-affinity binding and inhibition of calcium transport in a clonal cell line. ( Toll, L, 1982) |
"Nicardipine, one of the dihydropyridine derivatives, in a nanomolar concentration range suppressed the high K+ -induced neurotransmitter release from cultured neuronal cells (chick embryonic neural retina cells and clonal rat pheochromocytoma cells)." | 3.66 | Dihydropyridines as potent calcium channel blockers in neuronal cells. ( Ogura, A; Takahashi, M, 1983) |
"Bradykinin treatment produced a significant incorporation of [32P]-phosphate into two phosphopeptides of tryptically digested tyrosine hydroxylase." | 1.28 | Regulation of tyrosine hydroxylase activity in pheochromocytoma PC-12 cells by bradykinin. ( Bowyer, JF; Houchi, H; Masserano, JM; Weiner, N, 1990) |
" Dose-response curves to K+ show that following differentiation, cells become more sensitive, releasing transmitter at lower K+ concentrations." | 1.27 | Nerve growth factor modulates the drug sensitivity of neurotransmitter release from PC-12 cells. ( Kongsamut, S; Miller, RJ, 1986) |
"Nicardipine was used to control hypertensive episodes." | 1.27 | Blood glucose control by an artificial endocrine pancreas in a patient with phaeochromocytoma. ( Hamaji, M; Kawamori, R; Kawashima, Y; Mashimo, T; Miyata, M; Nakao, K; Shichiri, M, 1985) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 30 (69.77) | 18.7374 |
1990's | 9 (20.93) | 18.2507 |
2000's | 2 (4.65) | 29.6817 |
2010's | 2 (4.65) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Mengesha, RE | 1 |
Rother, RB | 1 |
Ginther, DN | 1 |
Kriegler, S | 1 |
Kanthan, R | 1 |
Shaw, JM | 1 |
Zhang, Y | 1 |
Tao, J | 1 |
Huang, H | 1 |
Ding, G | 1 |
Cheng, Y | 1 |
Sun, W | 1 |
Serfas, D | 1 |
Shoback, DM | 1 |
Lorell, BH | 1 |
Albus, U | 1 |
Habermann, E | 1 |
Ferry, DR | 1 |
Glossmann, H | 1 |
Greenberg, DA | 3 |
Cooper, EC | 2 |
Carpenter, CL | 3 |
Shalaby, IA | 1 |
Kongsamut, S | 3 |
Freedman, SB | 1 |
Miller, RJ | 3 |
Toll, L | 1 |
Ogura, A | 2 |
Takahashi, M | 3 |
Bartorelli, A | 1 |
Fiorentini, C | 1 |
Fabbiocchi, F | 1 |
Loaldi, A | 1 |
Guazzi, M | 1 |
Ohtsu, S | 1 |
Miyakoshi, J | 1 |
Tsukada, T | 1 |
Hiraoka, M | 1 |
Abe, M | 1 |
Takebe, H | 1 |
Kudoh, Y | 1 |
Kuroda, S | 1 |
Shimamoto, K | 1 |
Iimura, O | 1 |
Furino, A | 1 |
Massagli, C | 1 |
Pesce, CV | 1 |
Vulpis, V | 1 |
Tantawanichpisal, D | 1 |
Rujiwanichkul, K | 1 |
Yipintsoi, T | 1 |
Rajalingam, V | 1 |
Chao, SM | 1 |
Tan, CL | 1 |
Tan, IK | 1 |
Starikova, AM | 1 |
Chvanov, MA | 1 |
Pogorelaya, NC | 1 |
Kostyuk, PG | 1 |
Schindelholz, B | 1 |
Reber, BF | 1 |
Houchi, H | 1 |
Masserano, JM | 1 |
Bowyer, JF | 1 |
Weiner, N | 1 |
Smets, LA | 1 |
Janssen, M | 1 |
Rutgers, M | 1 |
Ritzen, K | 1 |
Buttenhuis, C | 1 |
Schulick, A | 1 |
Gusovsky, F | 2 |
Yasumoto, T | 2 |
Daly, JW | 2 |
Tsukui, H | 1 |
Hatanaka, H | 1 |
Messing, RO | 1 |
Harris, KM | 1 |
Schmid-Antomarchi, H | 1 |
Hugues, M | 1 |
Lazdunski, M | 1 |
Blake, GM | 2 |
Lewington, VJ | 2 |
Zivanovic, MA | 2 |
Ackery, DM | 2 |
Takahashi, S | 1 |
Nakai, T | 1 |
Fujiwara, R | 1 |
Kutsumi, Y | 1 |
Tamai, T | 1 |
Miyabo, S | 1 |
Rojas, E | 1 |
Grabensee, B | 1 |
Saunier, B | 1 |
Garcin, JM | 1 |
Archane, MI | 1 |
Gautier, D | 1 |
Colson, P | 1 |
Ribstein, J | 1 |
Mimran, A | 1 |
Grolleau, D | 1 |
Chaptal, PA | 1 |
Roquefeuil, B | 1 |
Proye, C | 1 |
Cecat, P | 1 |
Thevenin, D | 1 |
Petillot, P | 1 |
Lefebvre, J | 1 |
Wemeau, JL | 1 |
Chari, P | 1 |
Katariya, RN | 1 |
Venkataraman, RK | 1 |
Trikha, A | 1 |
Fleming, JS | 1 |
Arai, T | 1 |
Hatano, Y | 1 |
Ishida, H | 1 |
Mori, K | 1 |
Favre, L | 2 |
Forster, A | 1 |
Fathi, M | 1 |
Vallotton, MB | 2 |
Lenders, JW | 1 |
Sluiter, HE | 1 |
Thien, T | 1 |
Willemsen, J | 1 |
Guazzi, MD | 1 |
De Cesare, N | 1 |
Galli, C | 1 |
Salvioni, A | 1 |
Tamborini, G | 1 |
Tosi, E | 1 |
Chimori, K | 1 |
Miyazaki, S | 1 |
Nakajima, T | 1 |
Miura, K | 1 |
Hamaji, M | 1 |
Miyata, M | 1 |
Kawamori, R | 1 |
Shichiri, M | 1 |
Mashimo, T | 1 |
Nakao, K | 1 |
Kawashima, Y | 1 |
1 review available for nifedipine and Pheochromocytoma
Article | Year |
---|---|
Intracranial pheochromocytoma--a case of noradrenaline-secreting glomus jugulare tumor.
Topics: Adult; Cerebellar Neoplasms; Cerebellopontine Angle; Diagnosis, Differential; Diltiazem; Embolizatio | 1995 |
3 trials available for nifedipine and Pheochromocytoma
Article | Year |
---|---|
Phaeochromocytoma and hypertrophic cardiomyopathy: apparent suppression of symptoms and noradrenaline secretion by calcium-channel blockade.
Topics: Adrenal Gland Neoplasms; Adult; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Clinical Tri | 1983 |
[Clinical experience with alpha blockers and calcium antagonists in the perioperative treatment of pheochromocytoma].
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Humans; Hypertension; Male; Nifedipine; Phenoxyben | 1994 |
[Nifedipine as a vasodilator antihypertensive with a rapid action].
Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Brain Diseases; Cardiomyopathies; Emergencies; Hem | 1985 |
39 other studies available for nifedipine and Pheochromocytoma
Article | Year |
---|---|
MANAGEMENT OF PHEOCHROMOCYTOMA IN THE ABSENCE OF ALPHA BLOKERS: A CASE REPORT FROM AYDER REFERRAL HOSPITAL.
Topics: Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Anesthesia, General; Female; Humans; Intraoperat | 2015 |
Unexpected intra-operative diagnosis of a large cystic phaeochromocytoma and secondary nifedipine pharmacobezoar.
Topics: Adrenal Gland Neoplasms; Aged; Bezoars; Calcium Channel Blockers; Diagnosis, Differential; Female; H | 2012 |
Effects of celecoxib on voltage-gated calcium channel currents in rat pheochromocytoma (PC12) cells.
Topics: Adrenal Gland Neoplasms; Animals; Antineoplastic Agents; Barium; Calcium Channel Blockers; Calcium C | 2007 |
Novel 1,4-dihydropyridine (Bay K 8644) facilitates calcium-dependent [3H]noradrenaline release from PC 12 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1984 |
Calcium channel 'agonist' BAY K 8644 inhibits calcium antagonist binding to brain and PC12 cell membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1984 |
The effects of dihydropyridines on neurotransmitter release from cultured neuronal cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1984 |
Calcium antagonists High-affinity binding and inhibition of calcium transport in a clonal cell line.
Topics: Adrenal Gland Neoplasms; Animals; Binding, Competitive; Biological Transport, Active; Calcium; Calci | 1982 |
Differential effect of a dihydropyridine derivative to Ca2+ entry pathways in neuronal preparations.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Cerebral Cortex; Clone Cells; Do | 1984 |
Dihydropyridines as potent calcium channel blockers in neuronal cells.
Topics: Adrenal Gland Neoplasms; Animals; Calcium; Calcium Channel Blockers; Calcium Chloride; Chick Embryo; | 1983 |
[Nifedipine in the therapy of secondary hypertension].
Topics: Adrenal Gland Neoplasms; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Nifed | 1981 |
Enhancement of beta-galactosidase gene expression in rat pheochromocytoma cells by exposure to extremely low frequency magnetic fields.
Topics: Adrenal Gland Neoplasms; Animals; beta-Galactosidase; Colforsin; Dantrolene; Escherichia coli; Gene | 1995 |
Precipitous hypotension after nifedipine in pheochromocytoma: report of 2 cases.
Topics: Adrenal Gland Neoplasms; Adult; Fatal Outcome; Female; Humans; Hypotension; Nifedipine; Pheochromocy | 1993 |
Phaeochromocytoma--a rare cause of hypertension in an 11-year-old girl.
Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Calcium Channel Blockers; Catecholamines; Child; F | 1996 |
Nifedipine-induced morphological differentiation of rat pheochromocytoma cells.
Topics: Adrenal Gland Neoplasms; Animals; Calcium; Cell Differentiation; Cell Division; Kinetics; Mitosis; N | 1998 |
L-type Ca2+ channels and purinergic P2X2 cation channels participate in calcium-tyrosine kinase-mediated PC12 growth cone arrest.
Topics: Actins; Adenosine Triphosphate; Adrenal Gland Neoplasms; Animals; Calcium; Calcium Channel Blockers; | 2000 |
Regulation of tyrosine hydroxylase activity in pheochromocytoma PC-12 cells by bradykinin.
Topics: Animals; Bradykinin; Calcium; Colforsin; Cyclic AMP; Enzyme Activation; Lanthanum; Nifedipine; Pheoc | 1990 |
Pharmacokinetics and intracellular distribution of the tumor-targeted radiopharmaceutical m-iodo-benzylguanidine in SK-N-SH neuroblastoma and PC-12 pheochromocytoma cells.
Topics: 3-Iodobenzylguanidine; Acetylcholine; Adrenal Gland Neoplasms; Animals; Antineoplastic Agents; Autor | 1991 |
Effects of maitotoxin on atrial natriuretic factor-mediated accumulation of cyclic GMP in PC12 cells.
Topics: Atrial Natriuretic Factor; Calcium; Cyclic GMP; Dose-Response Relationship, Drug; Ionomycin; Marine | 1990 |
Stimulation of calcium uptake in PC12 cells by the dihydropyridine agonist BAY K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1985 |
Neuronal differentiation of Ca2+ channel by nerve growth factor.
Topics: Adrenal Gland Neoplasms; Adrenal Medulla; Animals; Calcium; Cell Differentiation; Cell Line; Clone C | 1985 |
Mechanism of calcium channel inhibition by phenytoin: comparison with classical calcium channel antagonists.
Topics: Adrenal Gland Neoplasms; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Carbachol; Cell | 1985 |
Protein kinase C mediated regulation of calcium channels in PC-12 pheochromocytoma cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1986 |
Nerve growth factor modulates the drug sensitivity of neurotransmitter release from PC-12 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1986 |
Properties of the apamin-sensitive Ca2+-activated K+ channel in PC12 pheochromocytoma cells which hyper-produce the apamin receptor.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1986 |
Glomerular filtration rate and the kinetics of 123I-metaiodobenzylguanidine.
Topics: 3-Iodobenzylguanidine; Adult; Combined Modality Therapy; Glomerular Filtration Rate; Humans; Iodine | 1989 |
Effectiveness of long-acting nifedipine in pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Blood Pressure; Delayed-Action Preparations; Epinephrine; Female; Humans; H | 1989 |
Differential effects of maitotoxin on ATP secretion and on phosphoinositide breakdown in rat pheochromocytoma cells.
Topics: Adenosine Triphosphate; Adrenal Gland Neoplasms; Animals; Calcium; Dose-Response Relationship, Drug; | 1988 |
[Therapy of the hypertensive crisis].
Topics: Administration, Oral; Adrenergic beta-Antagonists; Calcium Channel Blockers; Clonidine; Dihydralazin | 1985 |
[Hypertensive attacks in pheochromocytoma. Value of nifedipine by the sublingual route].
Topics: Adrenal Gland Neoplasms; Adult; Humans; Hypertension; Male; Nifedipine; Pheochromocytoma | 1986 |
[Preparation for surgery of a pheochromocytoma with a calcium channel blockader].
Topics: Adrenal Gland Neoplasms; Adult; Blood Pressure; Humans; Male; Middle Aged; Nifedipine; Pheochromocyt | 1988 |
[Calcium channel blockers in the surgery of pheochromocytoma].
Topics: Adrenal Gland Neoplasms; Female; Humans; Intraoperative Period; Nifedipine; Pheochromocytoma; Preope | 1988 |
Nifedipine and surgical removal of phaeochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Arrhythmias, Cardiac; Female; Humans; Hypertension; Intraoperative C | 1988 |
Modification by nifedipine of 131I-meta-iodobenzylguanidine kinetics in malignant phaeochromocytoma.
Topics: 3-Iodobenzylguanidine; Adrenal Gland Neoplasms; Humans; Iodine Radioisotopes; Iodobenzenes; Nifedipi | 1988 |
Use of nicardipine in the anesthetic management of pheochromocytoma.
Topics: Adult; Anesthesia, Local; Blood Pressure; Cardiac Output; Epinephrine; Female; Fentanyl; Heart Rate; | 1986 |
Calcium-channel inhibition in pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Blood Pressure; Epinephrine; Female; Humans; Male; Metoclopramide; M | 1986 |
Treatment of a phaeochromocytoma of the urinary bladder with nifedipine.
Topics: Adult; Female; Humans; Hypertension; Nifedipine; Pheochromocytoma; Urinary Bladder Neoplasms | 1985 |
Nifedipine in pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Blood Pressure; Catecholamines; Female; Humans; Male; Middle Aged; N | 1986 |
Preoperative management of pheochromocytoma with the calcium-antagonist nifedipine.
Topics: Adrenal Gland Neoplasms; Adult; Blood Pressure; Electrocardiography; Female; Humans; Hypertension; N | 1985 |
Blood glucose control by an artificial endocrine pancreas in a patient with phaeochromocytoma.
Topics: Adrenal Gland Neoplasms; Blood Glucose; Calcium Channel Blockers; Catecholamines; Diabetes Mellitus, | 1985 |