nifedipine has been researched along with Parkinson Disease in 3 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, XJ | 1 |
| Xu, JX | 1 |
| Hashimoto, T | 1 |
| Yabe-Nishimura, C | 1 |
| Nishino, N | 1 |
| Noguchi-Kuno, SA | 1 |
| Sugiyama, T | 1 |
| Tanaka, C | 1 |
3 other studies available for nifedipine and Parkinson Disease
| Article | Year |
|---|---|
Possible involvement of Ca2+ signaling in rotenone-induced apoptosis in human neuroblastoma SH-SY5Y cells.
Topics: Apoptosis; Calcium; Calcium Channel Blockers; Caspases; Cell Cycle; Cell Line, Tumor; Chelating Agen | 2005 |
Oxidative metabolite of dopamine, 3,4-dihydroxyphenylacetaldehyde, induces dopamine release from PC12 cells by a Ca2+-independent mechanism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Calcium; Calcium Channel Blockers; Dopamine; L-Lactate Dehy | 2002 |
[3H]Nitrendipine binding sites are decreased in the substantia nigra and striatum of the brain from patients with Parkinson's disease.
Topics: Aged; Binding Sites; Caudate Nucleus; Corpus Striatum; Female; Globus Pallidus; Humans; Male; Nifedi | 1986 |