nifedipine has been researched along with Pancreatic Neoplasms in 15 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The high-voltage-activated (HVA) Ba2+ currents of rat insulinoma RINm5F cells insensitive to dihydropyridines (DHP) and omega-conotoxin GVIA (omega-CTx-GVIA) have been studied for their sensitivity to omega-agatoxin-IVA (omega-Aga-IVA) and omega-CTx-MVIIC." | 7.69 | Block of non-L-, non-N-type Ca2+ channels in rat insulinoma RINm5F cells by omega-agatoxin IVA and omega-conotoxin MVIIC. ( Carbone, E; Magnelli, V; Pollo, A; Sher, E, 1995) |
| "In hamster insulinoma (HIT) cells, maitotoxin (MTX) induces a time-dependent and concentration-dependent release of insulin that requires the presence of extracellular calcium." | 7.68 | Stimulatory effects of maitotoxin on insulin release in insulinoma HIT cells: role of calcium uptake and phosphoinositide breakdown. ( Daly, JW; Gusovsky, F; Soergel, DG; Yasumoto, T, 1990) |
| "The high-voltage-activated (HVA) Ba2+ currents of rat insulinoma RINm5F cells insensitive to dihydropyridines (DHP) and omega-conotoxin GVIA (omega-CTx-GVIA) have been studied for their sensitivity to omega-agatoxin-IVA (omega-Aga-IVA) and omega-CTx-MVIIC." | 3.69 | Block of non-L-, non-N-type Ca2+ channels in rat insulinoma RINm5F cells by omega-agatoxin IVA and omega-conotoxin MVIIC. ( Carbone, E; Magnelli, V; Pollo, A; Sher, E, 1995) |
| "Effects of genistein on insulin release were studied using MIN6 cells, a glucose-sensitive insulinoma cell line." | 3.68 | Genistein augments cyclic adenosine 3'5'-monophosphate(cAMP) accumulation and insulin release in MIN6 cells. ( Ishii, C; Ito, Y; Kato, N; Kawazu, S; Ohno, T; Shimizu, M; Tomono, S, 1993) |
| "In hamster insulinoma (HIT) cells, maitotoxin (MTX) induces a time-dependent and concentration-dependent release of insulin that requires the presence of extracellular calcium." | 3.68 | Stimulatory effects of maitotoxin on insulin release in insulinoma HIT cells: role of calcium uptake and phosphoinositide breakdown. ( Daly, JW; Gusovsky, F; Soergel, DG; Yasumoto, T, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 12 (80.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bose, B | 1 |
| Shenoy P, S | 1 |
| Ohno, T | 1 |
| Kato, N | 1 |
| Ishii, C | 1 |
| Shimizu, M | 1 |
| Ito, Y | 1 |
| Tomono, S | 1 |
| Kawazu, S | 1 |
| Bertrand, V | 2 |
| Bastié, MJ | 2 |
| Vaysse, N | 2 |
| Pradayrol, L | 2 |
| Magnelli, V | 1 |
| Pollo, A | 2 |
| Sher, E | 1 |
| Carbone, E | 2 |
| McArthur, CP | 1 |
| Fiorella, R | 1 |
| Saran, BM | 1 |
| Mogami, H | 1 |
| Shibata, H | 1 |
| Nobusawa, R | 1 |
| Ohnota, H | 1 |
| Satou, F | 1 |
| Miyazaki, J | 1 |
| Kojima, I | 1 |
| Marchetti, C | 1 |
| Amico, C | 1 |
| Podestà , D | 1 |
| Robello, M | 1 |
| Caraher, EM | 1 |
| Newsholme, P | 1 |
| Platano, D | 1 |
| Aicardi, G | 1 |
| Wang, L | 1 |
| Bhattacharjee, A | 1 |
| Fu, J | 1 |
| Li, M | 1 |
| Itami, A | 1 |
| Kato, M | 1 |
| Komoto, I | 1 |
| Doi, R | 1 |
| Hosotani, R | 1 |
| Shimada, Y | 1 |
| Imamura, M | 1 |
| Thorn, P | 1 |
| Petersen, OH | 1 |
| Soergel, DG | 1 |
| Gusovsky, F | 1 |
| Yasumoto, T | 1 |
| Daly, JW | 1 |
| Findlay, I | 1 |
| Dunne, MJ | 1 |
15 other studies available for nifedipine and Pancreatic Neoplasms
| Article | Year |
|---|---|
Non insulin producing cell line, MIA PaCa-2 is rendered insulin producing in vitro via mesenchymal epithelial transition.
Topics: Cell Line, Tumor; Epithelial-Mesenchymal Transition; Flow Cytometry; Humans; Insulin; Insulin Secret | 2013 |
Genistein augments cyclic adenosine 3'5'-monophosphate(cAMP) accumulation and insulin release in MIN6 cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cell Line; Cyclic AMP; Cytosol; Dose-Response Relatio | 1993 |
Inhibition of gastrin-induced proliferation of AR4-2J cells by calcium channel antagonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1994 |
Block of non-L-, non-N-type Ca2+ channels in rat insulinoma RINm5F cells by omega-agatoxin IVA and omega-conotoxin MVIIC.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Electric Stimulation; Insulin | 1995 |
Rare primary signet ring carcinoma of the pancreas.
Topics: Aged; Carcinoma, Signet Ring Cell; Fatal Outcome; Female; Female Urogenital Diseases; Humans; Hypert | 1995 |
Inhibition of ATP-sensitive K+ channel by a non-sulfonylurea compound KAD-1229 in a pancreatic beta-cell line, MIN 6 cell.
Topics: Action Potentials; Adenosine Triphosphate; Binding, Competitive; Calcium; Cell Membrane; Cobalt; Dos | 1994 |
Inactivation of voltage-dependent calcium current in an insulinoma cell line.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Chloride; Cricetinae; Culture Media; El | 1994 |
Different implications of Ca2+i and and Ca2+e in CCK/gastrin-induced amylase secretion in AR4-2J cells.
Topics: Amylases; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cholecystokinin; Enzyme Inhi | 1995 |
Investigation into the mechanisms of complement mediated cytotoxicity in pancreatic beta cells.
Topics: Animals; Apoptosis; Benzamides; Cell Death; Cell Line; Complement System Proteins; Culture Media; Gl | 1996 |
Up-regulation of L- and non-L, non-N-type Ca2+ channels by basal and stimulated protein kinase C activation in insulin-secreting RINm5F cells.
Topics: Adenosine Triphosphate; Animals; Barium; Cadmium; Cadmium Chloride; Calcium Channel Blockers; Calciu | 1996 |
Abnormally expressed low-voltage-activated calcium channels in beta-cells from NOD mice and a related clonal cell line.
Topics: Amiloride; Animals; Calcium Channel Blockers; Calcium Channels; Cell Line; Clone Cells; Electric Con | 1996 |
Human gastrinoma cells express calcium-sensing receptor.
Topics: Blotting, Southern; Calcium; Calcium Chloride; Dose-Response Relationship, Drug; Fluorescent Antibod | 2001 |
Activation of voltage-sensitive Ca2+ currents by vasopressin in an insulin-secreting cell line.
Topics: Animals; Barium; Biological Transport; Calcium; Calcium Channels; Dose-Response Relationship, Drug; | 1991 |
Stimulatory effects of maitotoxin on insulin release in insulinoma HIT cells: role of calcium uptake and phosphoinositide breakdown.
Topics: Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cinnarizine; Cricetinae; | 1990 |
Voltage-activated Ca2+ and K+ currents in an insulin-secreting cell line (RINm5F).
Topics: Animals; Calcium; Cell Line; Cell Membrane; Egtazic Acid; Insulin; Insulin Secretion; Insulinoma; Io | 1986 |