Page last updated: 2024-11-01

nifedipine and Pain

nifedipine has been researched along with Pain in 61 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"To compare nifedipine, naproxen, or placebo for pain relief during diagnostic hysteroscopy."9.69Efficacy of Oral Nifedipine, Naproxen, or Placebo for Pain Relief During Diagnostic Hysteroscopy in an Office Setting: A Randomized Pilot Study. ( Emanuel, MH; Hamerlynck, T; Rombaut, J; van Wessel, S; Vanhulle, A; Weyers, S, 2023)
"The aim of this prospective study was to assess the effectiveness in healing anal fissure (AF) of lacidipine, a calcium channel blocker with a better tolerability in comparison to other calcium antagonists."9.10Oral lacidipine in the treatment of anal fissure. ( Ansaloni, L; Bernabè, A; Gardini, G; Ghetti, R; Riccardi, R; Tranchino, RM, 2002)
"To assess the effects of verapamil and nifedipine on left ventricular function at rest and during exercise in patients with Prinzmetal's variant angina pectoris, 10 patients (6 men and 4 women with a mean age of 52 years) with variant angina were each treated for 2 months periods with placebo, verapamil (400 +/- 80 mg/day, mean +/- standard deviation [SD]) and nifedipine (82 +/- 31 mg/day)."9.05Effect of verapamil and nifedipine on left ventricular function at rest and during exercise in patients with Prinzmetal's variant angina pectoris. ( Corbett, J; Dehmer, GJ; Hillis, LD; Johnson, SM; Lewis, SE; Mauritson, DR; Willerson, JT, 1981)
" Reports on clinical use of bisphosphonates for bone pain in cancer, controlled release opioids, selection of laxatives for opioid-induced constipation and the calcium channel blocker nifedipine as an analgesic are described."8.81Analgesia issues in palliative care: bone pain, controlled release opioids, managing opioid-induced constipation and nifedipine as an analgesic. ( Fine, PG, 2002)
"Anal manometry was performed on eight healthy volunteers and 15 patients with chronic anal fissure before and after oral administration of nifedipine 20 mg."7.70Oral nifedipine reduces resting anal pressure and heals chronic anal fissure. ( Cook, TA; Humphreys, MM; McC Mortensen, NJ, 1999)
"We have confirmed the usefulness of nifedipine in the treatment of pain present in lesions of multiple skin leiomyomata."7.69Pain in multiple leiomyomas alleviated by nifedipine. ( Chandi, SM; George, S; Jacob, M; Pulimood, S, 1997)
"These results suggest that by lowering capsaicin-induced neural activity in nociceptive terminals, diltiazem decreases pain and neurogenic inflammation and may be useful as both an analgesic and an antiinflammatory agent in the eye."7.68Reduction of capsaicin-induced ocular pain and neurogenic inflammation by calcium antagonists. ( Belmonte, C; Gallar, J; Garcia de la Rubia, P; Gonzalez, GG, 1993)
"Several notifications of eye pain and blurred vision associated with treatment with nifedipine were received by New Zealand's Intensive Medicines Monitoring Programme."7.67Eye pain with nifedipine and disturbance of taste with captopril: a mutually controlled study showing a method of postmarketing surveillance. ( Coulter, DM, 1988)
"The effects of the calcium antagonist nifedipine on uterine activity and lower abdominal pain were studied during the first menstrual day in 10 women with severe primary dysmenorrhoea."7.66Effects of nifedipine on myometrial activity and lower abdominal pain in women with primary dysmenorrhoea. ( Andersson, KE; Ulmsten, U, 1978)
"To compare nifedipine, naproxen, or placebo for pain relief during diagnostic hysteroscopy."5.69Efficacy of Oral Nifedipine, Naproxen, or Placebo for Pain Relief During Diagnostic Hysteroscopy in an Office Setting: A Randomized Pilot Study. ( Emanuel, MH; Hamerlynck, T; Rombaut, J; van Wessel, S; Vanhulle, A; Weyers, S, 2023)
"We recommend the addition of either oral or topical nifedipine to conservative measures to significantly improve pain relief and healing rates in patients with fissure-in-ano."5.17Randomized controlled pilot trial of nifedipine as oral therapy vs. topical application in the treatment of fissure-in-ano. ( Agrawal, V; Gupta, R; Kaushal, G, 2013)
"The aim of this prospective study was to assess the effectiveness in healing anal fissure (AF) of lacidipine, a calcium channel blocker with a better tolerability in comparison to other calcium antagonists."5.10Oral lacidipine in the treatment of anal fissure. ( Ansaloni, L; Bernabè, A; Gardini, G; Ghetti, R; Riccardi, R; Tranchino, RM, 2002)
"A double-blind randomized, clinical trial was conducted in 43 patients to evaluate the efficacy of sublingual nifedipine in the treatment of pain in renal colic."5.06Nifedipine in the treatment of renal colic. ( Lloret, J; Monmany, J; More, J; Muñoz, J; Puig, X; Vila, A, 1986)
"To assess the effects of verapamil and nifedipine on left ventricular function at rest and during exercise in patients with Prinzmetal's variant angina pectoris, 10 patients (6 men and 4 women with a mean age of 52 years) with variant angina were each treated for 2 months periods with placebo, verapamil (400 +/- 80 mg/day, mean +/- standard deviation [SD]) and nifedipine (82 +/- 31 mg/day)."5.05Effect of verapamil and nifedipine on left ventricular function at rest and during exercise in patients with Prinzmetal's variant angina pectoris. ( Corbett, J; Dehmer, GJ; Hillis, LD; Johnson, SM; Lewis, SE; Mauritson, DR; Willerson, JT, 1981)
" Reports on clinical use of bisphosphonates for bone pain in cancer, controlled release opioids, selection of laxatives for opioid-induced constipation and the calcium channel blocker nifedipine as an analgesic are described."4.81Analgesia issues in palliative care: bone pain, controlled release opioids, managing opioid-induced constipation and nifedipine as an analgesic. ( Fine, PG, 2002)
" We present the case of limb ischemia secondary to accidental intra-arterial buprenorphine/naloxone film injection successfully treated with sublingual nitroglycerin."3.96Use of Sublingual Nitrates for Management of Limb Ischemia Secondary to Inadvertent Intra-Arterial Buprenorphine/Naloxone (Suboxone®) Film Injection. ( Franqui-Rivera, H; Gonzalez-Cordero, A; Reyes, M; Rivera-Gonzalez, J, 2020)
"1% nitroglycerin on demand; 3: internal anal sphincterotomy if hypertrophy of the internal anal sphincter was demonstrated by anal ultrasonography and no improvement was confirmed with the previous steps of treatment)."3.73Sequential treatment for proctalgia fugax. Mid-term follow-up. ( Aguilella Diago, V; Elía Guedea, M; Gracia Solanas, JA; Martínez Díez, M; Ramírez Rodríguez, JM, 2005)
"Anal manometry was performed on eight healthy volunteers and 15 patients with chronic anal fissure before and after oral administration of nifedipine 20 mg."3.70Oral nifedipine reduces resting anal pressure and heals chronic anal fissure. ( Cook, TA; Humphreys, MM; McC Mortensen, NJ, 1999)
" After treatment with a sustained release formulation of the calcium antagonist, nifedipine, their blood pressure returned to normal, anal tone was reduced, and the frequency and intensity of anal pain was suppressed."3.69Hereditary proctalgia fugax and constipation: report of a second family. ( Celik, AF; Donnelly, TC; Katsinelos, P; Khan, MI; Read, NW, 1995)
"We have confirmed the usefulness of nifedipine in the treatment of pain present in lesions of multiple skin leiomyomata."3.69Pain in multiple leiomyomas alleviated by nifedipine. ( Chandi, SM; George, S; Jacob, M; Pulimood, S, 1997)
"These results suggest that by lowering capsaicin-induced neural activity in nociceptive terminals, diltiazem decreases pain and neurogenic inflammation and may be useful as both an analgesic and an antiinflammatory agent in the eye."3.68Reduction of capsaicin-induced ocular pain and neurogenic inflammation by calcium antagonists. ( Belmonte, C; Gallar, J; Garcia de la Rubia, P; Gonzalez, GG, 1993)
"The effect of acute and chronic treatment with three antidepressant drugs on the cortical L-type calcium channel (measured as [3H]nitrendipine binding sites) and on the responsiveness to pain (assessed in the hot-plate test) was tested on the Wistar rat."3.68Role of calcium channels in effects of antidepressant drugs on responsiveness to pain. ( Antkiewicz-Michaluk, L; Michaluk, J; Romańska, I; Vetulani, J, 1991)
"The effects of the calcium channel antagonists diltiazem, nifedipine and verapamil and the calcium channel agonist, BAY K 8644, on offensive and defensive aggression and defeat-induced opioid analgesia were examined in male mice in resident-intruder interactions."3.67Aggression and defeat-induced opioid analgesia displayed by mice are modified by calcium channel antagonists and agonists. ( Kavaliers, M, 1987)
"Several notifications of eye pain and blurred vision associated with treatment with nifedipine were received by New Zealand's Intensive Medicines Monitoring Programme."3.67Eye pain with nifedipine and disturbance of taste with captopril: a mutually controlled study showing a method of postmarketing surveillance. ( Coulter, DM, 1988)
"The effectiveness of nifedipine in treating angina pectoris at rest was evaluated in 14 patients with frequent ischemic episodes associated with S-T segment elevation or depression."3.66Treatment of angina at rest with nifedipine: a short-term controlled study. ( Bobba, P; Chimienti, M; Medici, A; Previtali, M; Ray, M; Salerno, JA; Specchia, G; Tavazzi, L, 1980)
"The effects of the calcium antagonist nifedipine on uterine activity and lower abdominal pain were studied during the first menstrual day in 10 women with severe primary dysmenorrhoea."3.66Effects of nifedipine on myometrial activity and lower abdominal pain in women with primary dysmenorrhoea. ( Andersson, KE; Ulmsten, U, 1978)
"To compare the efficacy of periprostatic nerve block (PNB) alone vs PNB combined with the local administration of a 1."2.74Periprostatic nerve block (PNB) alone vs PNB combined with an anaesthetic-myorelaxant agent cream for prostate biopsy: a prospective, randomized double-arm study. ( Cantiello, F; Di Meo, S; Fusco, F; Iannuzzo, M; Imbimbo, C; Imperatore, V; Mirone, V; Scibelli, G, 2009)
"Nifedipine has been shown to decrease human ureteral spasm in vitro."2.66Nifedipine for the relief of renal colic: a double-blind, placebo-controlled clinical trial. ( Bossart, PJ; Caravati, EM; Hartsell, SC; Martinez, JC; Runge, JW; Williamson, SG, 1989)
"Nimodipine was further studied using a higher and escalating doses of morphine (20-30 mg/kg twice daily for 14 days)."1.35Nimodipine is more effective than nifedipine in attenuating morphine tolerance on chronic co-administration in the rat tail-flick test. ( Gupta, A; Mishra, P; Ray, SB; Verma, D; Wadhwa, S, 2008)
"Cilnidipine is a 1,4-dihydropyridine-derived voltage-dependent calcium channel (VDCC) blocker and suppresses N-type VDCC currents in addition to L-type VDCC currents."1.35Suppression of formalin-induced nociception by cilnidipine, a voltage-dependent calcium channel blocker. ( Iwata, S; Koganei, H; Shoji, M, 2009)
"Breast pain is a common complaint among lactating women."1.33Vasospasm of the nipple presenting as painful lactation. ( McKenna, DS; Page, SM, 2006)
"Rats treated with nifedipine alone had an increase in tail-flick latency of 122%, as measured by the area under the curve, compared to rats treated with DMSO alone."1.29Ondansetron blocks nifedipine-induced analgesia in rats. ( Hunt, TE; Wu, W; Zbuzek, VK, 1996)

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-199023 (37.70)18.7374
1990's15 (24.59)18.2507
2000's12 (19.67)29.6817
2010's7 (11.48)24.3611
2020's4 (6.56)2.80

Authors

AuthorsStudies
Baraldi, PG1
Preti, D1
Materazzi, S1
Geppetti, P1
Beebe, X1
Darczak, D1
Henry, RF1
Vortherms, T1
Janis, R1
Namovic, M1
Donnelly-Roberts, D1
Kage, KL1
Surowy, C1
Milicic, I1
Niforatos, W1
Swensen, A1
Marsh, KC1
Wetter, JM1
Franklin, P1
Baker, S1
Zhong, C1
Simler, G1
Gomez, E1
Boyce-Rustay, JM1
Zhu, CZ1
Stewart, AO1
Jarvis, MF1
Scott, VE1
Vivier, D1
Bennis, K1
Lesage, F1
Ducki, S1
van Wessel, S1
Rombaut, J1
Vanhulle, A1
Emanuel, MH1
Hamerlynck, T1
Weyers, S1
Steen, CJ1
Yap, RJ1
Asghari-Jafarabadi, M1
Sutton, A1
Chin, M1
Carne, P1
Bell, SW1
McMurrick, PJ1
Gallego, H1
Aleshaki, JS1
Rivera-Gonzalez, J1
Gonzalez-Cordero, A1
Reyes, M1
Franqui-Rivera, H1
Jansen, S1
Sampene, K1
Agrawal, V1
Kaushal, G1
Gupta, R1
Pickard, R1
Starr, K1
MacLennan, G1
Kilonzo, M1
Lam, T1
Thomas, R1
Burr, J1
Norrie, J1
McPherson, G1
McDonald, A1
Shearer, K1
Gillies, K1
Anson, K1
Boachie, C1
N'Dow, J1
Burgess, N1
Clark, T1
Cameron, S1
McClinton, S1
Ray, SB1
Mishra, P1
Verma, D1
Gupta, A1
Wadhwa, S1
Cantiello, F1
Imperatore, V1
Iannuzzo, M1
Scibelli, G1
Di Meo, S1
Fusco, F1
Imbimbo, C1
Mirone, V1
Koganei, H1
Shoji, M1
Iwata, S1
Wu, M1
Chason, R1
Wong, M1
Ansaloni, L1
Bernabè, A1
Ghetti, R1
Riccardi, R1
Tranchino, RM1
Gardini, G1
Fine, PG1
Anderson, JE1
Held, N1
Wright, K1
de la Portilla, F1
Borrero, JJ1
Rafel, E1
Gracia Solanas, JA1
Ramírez Rodríguez, JM1
Elía Guedea, M1
Aguilella Diago, V1
Martínez Díez, M1
Page, SM1
McKenna, DS1
Takahashi, A1
Mikami, M1
Yang, J1
Buell, C1
Tobinick, E1
Lamp, K1
Sufit, RL1
Peters, HA1
Johnson, SM1
Mauritson, DR1
Corbett, J1
Dehmer, GJ1
Lewis, SE1
Willerson, JT1
Hillis, LD1
Abinader, E1
Shahar, J1
Abraham, Z1
Cohen, A1
Haim, S1
Cargill, G1
Theodore, C1
Paolaggi, JA1
Davies, HA1
Lewis, M1
Rhodes, J1
Henderson, A1
Tiefenbrunn, AJ1
Sobel, BE1
Gowda, S1
McKnight, RC1
Ludbrook, PA1
Previtali, M1
Salerno, JA1
Tavazzi, L1
Ray, M1
Medici, A1
Chimienti, M1
Specchia, G1
Bobba, P1
Wong, CH1
Dey, P1
Yarmush, J1
Wu, WH1
Zbuzek, VK2
Celik, AF1
Katsinelos, P1
Read, NW1
Khan, MI1
Donnelly, TC1
Gonzalez, GG1
Garcia de la Rubia, P1
Gallar, J1
Belmonte, C1
Hunt, TE1
Wu, W1
George, S1
Pulimood, S1
Jacob, M1
Chandi, SM1
Sluka, KA1
Cook, TA1
Humphreys, MM1
McC Mortensen, NJ1
Assi, AA1
Lown, B1
Andersson, KE1
Ulmsten, U1
Jariwalla, AG1
Anderson, EG1
Antkiewicz-Michaluk, L2
Romańska, I2
Michaluk, J2
Vetulani, J2
Vedder, H1
Otten, U1
Ogawa, S1
Kuroda, K1
Kikuchi, T1
Shirai, H1
Furusawa, M1
Akamine, Y1
Satoh, T1
Fujii, M1
Wakayama, S1
Koizumi, M1
Bosker, H1
Jordan, RD1
Sindet-Pedersen, S1
Koole, R1
al-Humayyd, MS1
Laroche, M1
Jacquemier, JM1
Montane de la Roque, P1
Arlet, J1
Mazières, B1
Farcot, JM1
Grasser, C1
Muller, JF1
Kavaliers, M3
Kraus, A1
Caravati, EM1
Runge, JW1
Bossart, PJ1
Martinez, JC1
Hartsell, SC1
Williamson, SG1
Powell-Tuck, J1
MacRae, KD1
Healy, MJ1
Lennard-Jones, JE1
Parkins, RA1
Geller, LI1
Petrenko, VF1
Coulter, DM1
Kelly, SP1
Walley, TJ1
Archer, CB1
Greaves, MW1
Mattioli, G1
Cioni, G1
Andreoli, C1
Lloret, J1
Vila, A1
Puig, X1
Monmany, J1
Muñoz, J1
More, J1

Reviews

4 reviews available for nifedipine and Pain

ArticleYear
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
    Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Pe

2010
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
    Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11

    Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Struc

2016
Analgesia issues in palliative care: bone pain, controlled release opioids, managing opioid-induced constipation and nifedipine as an analgesic.
    Journal of pain & palliative care pharmacotherapy, 2002, Volume: 16, Issue:1

    Topics: Adult; Analgesics; Analgesics, Opioid; Bone and Bones; Calcium Channel Blockers; Cathartics; Constip

2002
[Pain after sympathectomy].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1990, Volume: 31, Issue:4

    Topics: Aged; Analgesics; Autonomic Nervous System; Ganglionectomy; Humans; Lumbosacral Region; Middle Aged;

1990

Trials

11 trials available for nifedipine and Pain

ArticleYear
Efficacy of Oral Nifedipine, Naproxen, or Placebo for Pain Relief During Diagnostic Hysteroscopy in an Office Setting: A Randomized Pilot Study.
    Journal of minimally invasive gynecology, 2023, Volume: 30, Issue:6

    Topics: Double-Blind Method; Female; Humans; Hysteroscopy; Naproxen; Nifedipine; Pain; Pilot Projects; Pregn

2023
Topical nifedipine for post-haemorrhoidectomy pain relief: randomized, prospective, double-blind trial protocol.
    BJS open, 2023, 09-05, Volume: 7, Issue:5

    Topics: Administration, Topical; Double-Blind Method; Hemorrhoidectomy; Humans; Nifedipine; Pain; Prospectiv

2023
Randomized controlled pilot trial of nifedipine as oral therapy vs. topical application in the treatment of fissure-in-ano.
    American journal of surgery, 2013, Volume: 206, Issue:5

    Topics: Administration, Oral; Administration, Topical; Adult; Calcium Channel Blockers; Female; Fissure in A

2013
Use of drug therapy in the management of symptomatic ureteric stones in hospitalised adults: a multicentre, placebo-controlled, randomised controlled trial and cost-effectiveness analysis of a calcium channel blocker (nifedipine) and an alpha-blocker (tam
    Health technology assessment (Winchester, England), 2015, Volume: 19, Issue:63

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Calcium Channel Blockers; Cost-Benefit Analysis; Fem

2015
Periprostatic nerve block (PNB) alone vs PNB combined with an anaesthetic-myorelaxant agent cream for prostate biopsy: a prospective, randomized double-arm study.
    BJU international, 2009, Volume: 103, Issue:9

    Topics: Aged; Anesthetics, Local; Biopsy, Needle; Drug Therapy, Combination; Epidemiologic Methods; Humans;

2009
Oral lacidipine in the treatment of anal fissure.
    Techniques in coloproctology, 2002, Volume: 6, Issue:2

    Topics: Administration, Oral; Adult; Aged; Calcium Channel Blockers; Dihydropyridines; Female; Fissure in An

2002
Effect of verapamil and nifedipine on left ventricular function at rest and during exercise in patients with Prinzmetal's variant angina pectoris.
    The American journal of cardiology, 1981, Volume: 47, Issue:6

    Topics: Angina Pectoris; Angina Pectoris, Variant; Exercise Test; Female; Heart Ventricles; Hemodynamics; Hu

1981
Nifedipine for the relief of renal colic: a double-blind, placebo-controlled clinical trial.
    Annals of emergency medicine, 1989, Volume: 18, Issue:4

    Topics: Adult; Clinical Trials as Topic; Colic; Double-Blind Method; Female; Humans; Male; Middle Aged; Musc

1989
A defence of the small clinical trial: evaluation of three gastroenterological studies.
    British medical journal (Clinical research ed.), 1986, Mar-01, Volume: 292, Issue:6520

    Topics: Adult; Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Colonic Diseases, Functi

1986
Time sequence of anginal pain.
    Clinical cardiology, 1986, Volume: 9, Issue:4

    Topics: Adult; Aged; Angina Pectoris; Circadian Rhythm; Female; Humans; Isosorbide Dinitrate; Male; Metoprol

1986
Nifedipine in the treatment of renal colic.
    Methods and findings in experimental and clinical pharmacology, 1986, Volume: 8, Issue:9

    Topics: Adult; Blood Pressure; Colic; Female; Heart Rate; Humans; Kidney Diseases; Male; Nifedipine; Pain

1986

Other Studies

46 other studies available for nifedipine and Pain

ArticleYear
Synthesis and SAR of 4-aminocyclopentapyrrolidines as N-type Ca²⁺ channel blockers with analgesic activity.
    Bioorganic & medicinal chemistry, 2012, Jul-01, Volume: 20, Issue:13

    Topics: Acetamides; Analgesics; Animals; Behavior, Animal; Calcium Channel Blockers; Calcium Channels, N-Typ

2012
Raynaud phenomenon of the nipple successfully treated with nifedipine and gabapentin.
    Cutis, 2020, Volume: 105, Issue:6

    Topics: Adult; Breast Diseases; Breast Feeding; Female; Gabapentin; Humans; Nifedipine; Nipples; Pain; Rayna

2020
Use of Sublingual Nitrates for Management of Limb Ischemia Secondary to Inadvertent Intra-Arterial Buprenorphine/Naloxone (Suboxone®) Film Injection.
    Puerto Rico health sciences journal, 2020, Volume: 39, Issue:3

    Topics: Administration, Sublingual; Adult; Angiography; Anticoagulants; Buprenorphine, Naloxone Drug Combina

2020
Raynaud Phenomenon of the Nipple: An Under-Recognized Condition.
    Obstetrics and gynecology, 2019, Volume: 133, Issue:5

    Topics: Adult; Breast Diseases; Diagnosis, Differential; Female; Humans; Nifedipine; Nipples; Pain; Pregnanc

2019
Nimodipine is more effective than nifedipine in attenuating morphine tolerance on chronic co-administration in the rat tail-flick test.
    Indian journal of experimental biology, 2008, Volume: 46, Issue:4

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Calcium Channel Blockers; Disease Models, Animal; Dos

2008
Suppression of formalin-induced nociception by cilnidipine, a voltage-dependent calcium channel blocker.
    Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:10

    Topics: Administration, Oral; Amines; Analgesics; Animals; Calcium Channel Blockers; Calcium Channels, N-Typ

2009
Raynaud's phenomenon of the nipple.
    Obstetrics and gynecology, 2012, Volume: 119, Issue:2 Pt 2

    Topics: Adult; Breast Feeding; Female; Humans; Nifedipine; Nipples; Pain; Raynaud Disease; Vasodilator Agent

2012
Raynaud's phenomenon of the nipple: a treatable cause of painful breastfeeding.
    Pediatrics, 2004, Volume: 113, Issue:4

    Topics: Adult; Breast Diseases; Breast Feeding; Candidiasis; Diagnostic Errors; Female; Humans; Nifedipine;

2004
Hereditary vacuolar internal anal sphincter myopathy causing proctalgia fugax and constipation: a new case contribution.
    European journal of gastroenterology & hepatology, 2005, Volume: 17, Issue:3

    Topics: Aged; Anus Diseases; Calcium Channel Blockers; Constipation; Female; Humans; Hypertrophy; Muscle, Sm

2005
Sequential treatment for proctalgia fugax. Mid-term follow-up.
    Revista espanola de enfermedades digestivas, 2005, Volume: 97, Issue:7

    Topics: Acute Disease; Adult; Anal Canal; Anti-Anxiety Agents; Anus Diseases; Baths; Benzodiazepines; Endoso

2005
Vasospasm of the nipple presenting as painful lactation.
    Obstetrics and gynecology, 2006, Volume: 108, Issue:3 Pt 2

    Topics: Adult; Breast Feeding; Female; Humans; Lactation; Nifedipine; Nipples; Pain; Raynaud Disease; Vascul

2006
Hydrogen peroxide increases GABAergic mIPSC through presynaptic release of calcium from IP3 receptor-sensitive stores in spinal cord substantia gelatinosa neurons.
    The European journal of neuroscience, 2007, Volume: 25, Issue:3

    Topics: Animals; Calcium; Calcium Channel Blockers; gamma-Aminobutyric Acid; Hydrogen Peroxide; Inhibitory P

2007
Resolution of chronic pain and fingertip ulceration due to hand-arm vibration syndrome following combination pharmacotherapy.
    Archives of dermatology, 2007, Volume: 143, Issue:10

    Topics: Chronic Disease; Drug Therapy, Combination; Hand-Arm Vibration Syndrome; Humans; Male; Middle Aged;

2007
Nifedipine relieves exercise-exacerbated myalgias.
    Muscle & nerve, 1984, Volume: 7, Issue:8

    Topics: Adult; Electromyography; Female; Humans; Middle Aged; Muscle Cramp; Muscles; Nifedipine; Pain; Physi

1984
Production of paradoxical chest pains by nifedipine.
    Irish medical journal, 1983, Volume: 76, Issue:4

    Topics: Adult; Aged; Electrocardiography; Female; Humans; Male; Middle Aged; Nifedipine; Pain; Pyridines; Th

1983
Muscle relaxing agent in cutaneous leiomyoma.
    Dermatologica, 1983, Volume: 166, Issue:5

    Topics: Adult; Humans; Leiomyoma; Male; Nifedipine; Pain; Parasympatholytics; Pyridines; Skin Neoplasms

1983
Nifedipine for relief of esophageal chest pain?
    The New England journal of medicine, 1982, 07-15, Volume: 307, Issue:3

    Topics: Esophageal Diseases; Humans; Nifedipine; Pain; Pyridines; Thorax

1982
Nifedipine for relief of esophageal chest pain?
    The New England journal of medicine, 1982, Nov-11, Volume: 307, Issue:20

    Topics: Esophageal Diseases; Humans; Nifedipine; Pain; Pyridines; Spasm; Thorax

1982
Nifedipine blockade of ergonovine-induced coronary arterial spasm: angiographic documentation.
    The American journal of cardiology, 1981, Volume: 48, Issue:1

    Topics: Angina Pectoris; Angina Pectoris, Variant; Coronary Angiography; Electrocardiography; Ergonovine; Fe

1981
Treatment of angina at rest with nifedipine: a short-term controlled study.
    The American journal of cardiology, 1980, Volume: 45, Issue:4

    Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Electrocardiography; Female; Follow-Up Studies; Hemo

1980
Nifedipine-induced analgesia after epidural injection in rats.
    Anesthesia and analgesia, 1994, Volume: 79, Issue:2

    Topics: Analgesia, Epidural; Animals; Catheters, Indwelling; Dimethyl Sulfoxide; Hot Temperature; Male; Nife

1994
Hereditary proctalgia fugax and constipation: report of a second family.
    Gut, 1995, Volume: 36, Issue:4

    Topics: Adult; Aged; Anal Canal; Constipation; Family; Female; Humans; Hypertension; Hypertrophy; Male; Midd

1995
Reduction of capsaicin-induced ocular pain and neurogenic inflammation by calcium antagonists.
    Investigative ophthalmology & visual science, 1993, Volume: 34, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Capsaicin; Cornea; Dilti

1993
Ondansetron blocks nifedipine-induced analgesia in rats.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:3

    Topics: Analgesia; Analgesics; Animals; Dimethyl Sulfoxide; Injections, Intraperitoneal; Male; Nifedipine; O

1996
Pain in multiple leiomyomas alleviated by nifedipine.
    Pain, 1997, Volume: 73, Issue:1

    Topics: Adult; Calcium Channel Blockers; Chronic Disease; Female; Humans; Leiomyoma; Nifedipine; Pain; Skin;

1997
Blockade of N- and P/Q-type calcium channels reduces the secondary heat hyperalgesia induced by acute inflammation.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:1

    Topics: Animals; Arthritis; Calcium Channel Blockers; Calcium Channels; Hot Temperature; Hyperalgesia; Male;

1998
Oral nifedipine reduces resting anal pressure and heals chronic anal fissure.
    The British journal of surgery, 1999, Volume: 86, Issue:10

    Topics: Administration, Oral; Adult; Calcium Channel Blockers; Chronic Disease; Female; Fissure in Ano; Huma

1999
The influence of divalent cations on the analgesic effect of opioid and non-opioid drugs.
    Pharmacological research, 2001, Volume: 43, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Blood Pressure; Butorphanol; C

2001
Symposium on nifedipine and calcium flux inhibition in the treatment of coronary arterial spasm and myocardial ischemia. Introduction.
    The American journal of cardiology, 1979, Oct-22, Volume: 44, Issue:5

    Topics: Adult; Angina Pectoris; Calcium; Cardiomyopathies; Coronary Disease; Electrocardiography; Humans; Ma

1979
Effects of nifedipine on myometrial activity and lower abdominal pain in women with primary dysmenorrhoea.
    British journal of obstetrics and gynaecology, 1978, Volume: 85, Issue:2

    Topics: Adolescent; Adult; Dysmenorrhea; Female; Humans; Myometrium; Nifedipine; Pain; Pyridines

1978
Production of ischaemic cardiac pain by nifedipine.
    British medical journal, 1978, May-06, Volume: 1, Issue:6121

    Topics: Aged; Coronary Disease; Diagnosis, Differential; Female; Humans; Male; Middle Aged; Nifedipine; Pain

1978
Role of calcium channels in effects of antidepressant drugs on responsiveness to pain.
    Psychopharmacology, 1991, Volume: 105, Issue:2

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain Chemistry; Calcium Channels; Cerebral Cortex

1991
Biosynthesis and release of tachykinins from rat sensory neurons in culture.
    Journal of neuroscience research, 1991, Volume: 30, Issue:2

    Topics: Animals; Calcium; Capsaicin; Cells, Cultured; Chromatography, High Pressure Liquid; Ganglia, Spinal;

1991
[The effects of lowering of blood pressure on pain sensitivity in spontaneously hypertensive rats].
    Nihon Jinzo Gakkai shi, 1991, Volume: 33, Issue:11

    Topics: Animals; Blood Pressure; Hypertension; Indans; Male; Nifedipine; Pain; Pain Measurement; Rats; Rats,

1991
The transmandibular implant: a 13-year survey of its use.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1991, Volume: 49, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Dental Implantation, Endosseous; Female; Follow-Up Studies; Gingival

1991
Effect of diltiazem, nifedipine and verapamil on the antinociceptive action of acetylsalicylic acid in mice.
    General pharmacology, 1991, Volume: 22, Issue:1

    Topics: Analgesics; Animals; Aspirin; Benzoquinones; Diltiazem; Drug Interactions; Male; Mice; Nifedipine; P

1991
[Nifedipine per os relieves the pain caused by osteonecrosis of the femur head].
    Revue du rhumatisme et des maladies osteo-articulaires, 1990, Volume: 57, Issue:9

    Topics: Femur Head Necrosis; Humans; Nifedipine; Pain

1990
Effect of repetitive electroconvulsive treatment on sensitivity to pain and on [3H]nitrendipine binding sites in cortical and hippocampal membranes.
    Psychopharmacology, 1990, Volume: 101, Issue:2

    Topics: Animals; Calcium Channels; Cerebral Cortex; Electroshock; Hippocampus; Male; Membranes; Nifedipine;

1990
Aggression and defeat-induced opioid analgesia displayed by mice are modified by calcium channel antagonists and agonists.
    Neuroscience letters, 1987, Feb-10, Volume: 74, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1987
Stimulatory influences of calcium channel antagonists on stress-induced opioid analgesia and locomotor activity.
    Brain research, 1987, Apr-07, Volume: 408, Issue:1-2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1987
Calcium channel blockers inhibit the antagonistic effects of Phe-Met-Arg-Phe-amide (FMRFamide) on morphine- and stress-induced analgesia in mice.
    Brain research, 1987, Jul-14, Volume: 415, Issue:2

    Topics: Animals; Calcium; Drug Interactions; FMRFamide; Ion Channels; Mice; Morphine; Nervous System; Neurop

1987
Raynaud's phenomenon and nifedipine.
    The Journal of rheumatology, 1989, Volume: 16, Issue:7

    Topics: Humans; Nifedipine; Pain; Raynaud Disease

1989
[Disorders of esophageal motility as a cause of retrosternal pain].
    Terapevticheskii arkhiv, 1986, Volume: 58, Issue:2

    Topics: Adult; Diagnosis, Differential; Esophageal Diseases; Esophagitis, Peptic; Female; Gastrointestinal M

1986
Eye pain with nifedipine and disturbance of taste with captopril: a mutually controlled study showing a method of postmarketing surveillance.
    British medical journal (Clinical research ed.), 1988, Apr-16, Volume: 296, Issue:6629

    Topics: Adolescent; Adult; Aged; Captopril; Child; Evaluation Studies as Topic; Eye Diseases; Female; Humans

1988
Eye pain with nifedipine.
    British medical journal (Clinical research ed.), 1988, May-14, Volume: 296, Issue:6633

    Topics: Calcium Channel Blockers; Eye; Humans; Nifedipine; Pain; Regional Blood Flow

1988
Assessment of treatment for painful cutaneous leiomyomas.
    Journal of the American Academy of Dermatology, 1987, Volume: 17, Issue:1

    Topics: Adult; Humans; Leiomyoma; Male; Nifedipine; Pain; Pain Measurement; Phenoxybenzamine; Skin Neoplasms

1987