nifedipine has been researched along with Nerve Degeneration in 5 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The pathogenesis of this syndrome implicates immunopathological and toxic events such as the production of cytokines." | 1.29 | Tetrodotoxin blocks HIV coat protein (gp120) toxicity in primary neuronal cultures. ( Couratier, P; Diop, AG; Esclaire, F; Hugon, J; Lesort, M; Sindou, P, 1994) |
| "The nifedipine response was reproduced by isradipine and by verapamil with IC50 values of 9 and 100 nM, respectively." | 1.28 | Various Ca2+ entry blockers prevent glutamate-induced neurotoxicity. ( Memo, M; Pizzi, M; Ribola, M; Spano, P; Valerio, A, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, Z | 1 |
| Zhou, Y | 1 |
| Xie, J | 1 |
| Himeda, T | 1 |
| Kanbara, S | 1 |
| Oki, C | 1 |
| Kato, H | 1 |
| Araki, T | 1 |
| Diop, AG | 1 |
| Lesort, M | 1 |
| Esclaire, F | 1 |
| Sindou, P | 1 |
| Couratier, P | 1 |
| Hugon, J | 1 |
| Takadera, T | 1 |
| Maki, T | 1 |
| Hibino, H | 1 |
| Mohri, T | 1 |
| Pizzi, M | 1 |
| Ribola, M | 1 |
| Valerio, A | 1 |
| Memo, M | 1 |
| Spano, P | 1 |
5 other studies available for nifedipine and Nerve Degeneration
| Article | Year |
|---|---|
Nifedipine prevents iron accumulation and reverses iron-overload-induced dopamine neuron degeneration in the substantia nigra of rats.
Topics: Analysis of Variance; Animals; Calcium Channel Blockers; Cell Count; Chromatography, High Pressure L | 2012 |
Effects of chronic administration with nilvadipine against immunohistochemical changes related to aging in the mouse hippocampus.
Topics: Aging; Animals; Calcium Channel Blockers; Cell Death; Cell Proliferation; Cytoprotection; Dose-Respo | 2005 |
Tetrodotoxin blocks HIV coat protein (gp120) toxicity in primary neuronal cultures.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; HIV Envelope Protein | 1994 |
A cyclic AMP analog and high potassium prevent the death of cultured septal cholinergic neurons after nerve growth factor withdrawal.
Topics: Acetylcholinesterase; Animals; Bucladesine; Calcium Channel Blockers; Carbazoles; Cells, Cultured; C | 1996 |
Various Ca2+ entry blockers prevent glutamate-induced neurotoxicity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |