nifedipine has been researched along with Necrosis in 27 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of study is to investigate the effect of nifedipine on viral myocarditis in an animal model." | 7.75 | Nifedipine inhibits the activation of inflammatory and immune reactions in viral myocarditis. ( Hu, D; Liu, W; Matsumori, A; Shimada, M; Xiao, J, 2009) |
| " In the present study, we investigated the potential beneficial effect of chronic treatment with a dual L-type Ca2+ and slow Na+ channel blockers isradipine, on the development of necrosis in myopathic hamster hearts." | 7.72 | Isradipine prevents the development of spontaneously occurring cardiac necrosis in cardiomyopathic hamster. ( Bkaily, G; Chahine, M; D'Orléans-Juste, P; Jacques, D; Jasmin, G, 2003) |
| "We have used the model of L-2-chloropropionic acid (L-CPA)-induced selective cerebellar granule necrosis to study excitatory amino acid-induced necrotic cell death in vivo produced by the activation of N-methyl-D-aspartate (NMDA) receptors." | 7.69 | L-2-chloropropionic acid-induced cerebellar granule cell necrosis is potentiated by L-type calcium channel antagonists. ( Gyte, A; Moores, R; Pitts, M; Smith, JC; Upton, R; Widdowson, PS; Wyatt, I, 1997) |
| "This study was undertaken in order to determine whether the administration of nifedipine, a calcium channel blocker, could protect the liver from ischemic damage and to investigate its effect on the hepatic cellular energy status and cardio-vascular system after 60 minutes of hepatic ischemia in dogs." | 7.67 | The effect of nifedipine, a calcium channel blocker, on liver ischemia in dogs. ( Ishimaru, M; Kawano, N; Morioka, Y; Nagao, T; Sodeyama, M; Yoshimi, F, 1988) |
| "The aim of study is to investigate the effect of nifedipine on viral myocarditis in an animal model." | 3.75 | Nifedipine inhibits the activation of inflammatory and immune reactions in viral myocarditis. ( Hu, D; Liu, W; Matsumori, A; Shimada, M; Xiao, J, 2009) |
| " In the present study, we investigated the potential beneficial effect of chronic treatment with a dual L-type Ca2+ and slow Na+ channel blockers isradipine, on the development of necrosis in myopathic hamster hearts." | 3.72 | Isradipine prevents the development of spontaneously occurring cardiac necrosis in cardiomyopathic hamster. ( Bkaily, G; Chahine, M; D'Orléans-Juste, P; Jacques, D; Jasmin, G, 2003) |
| "We have used the model of L-2-chloropropionic acid (L-CPA)-induced selective cerebellar granule necrosis to study excitatory amino acid-induced necrotic cell death in vivo produced by the activation of N-methyl-D-aspartate (NMDA) receptors." | 3.69 | L-2-chloropropionic acid-induced cerebellar granule cell necrosis is potentiated by L-type calcium channel antagonists. ( Gyte, A; Moores, R; Pitts, M; Smith, JC; Upton, R; Widdowson, PS; Wyatt, I, 1997) |
| "This study was undertaken in order to determine whether the administration of nifedipine, a calcium channel blocker, could protect the liver from ischemic damage and to investigate its effect on the hepatic cellular energy status and cardio-vascular system after 60 minutes of hepatic ischemia in dogs." | 3.67 | The effect of nifedipine, a calcium channel blocker, on liver ischemia in dogs. ( Ishimaru, M; Kawano, N; Morioka, Y; Nagao, T; Sodeyama, M; Yoshimi, F, 1988) |
| "Pretreatment with verapamil reduced the size of these subendocardial infarcts from 34 +/- 8 to 8 +/- 3% of the ischemic circumflex vascular bed (anatomic area at risk)." | 2.37 | Effects of calcium-channel blockers on myocardial preservation during experimental acute myocardial infarction. ( Jennings, RB; Reimer, KA, 1985) |
| "(NZWxBXSB)F1 male mice were used as a model to study the effects of chronic administration of nifedipine and diltiazem on small coronary artery disease and mortality." | 1.28 | Effects of chronic oral administration of nifedipine and diltiazem on occlusive thrombus of small coronary arteries in (NZW x BXSB)F1 male mice. ( Fujiwara, H; Kawai, C; Kida, M; Kimura, K; Shibata, Y; Suzuka, H; Tanaka, M, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (33.33) | 18.7374 |
| 1990's | 7 (25.93) | 18.2507 |
| 2000's | 6 (22.22) | 29.6817 |
| 2010's | 5 (18.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Senel, S | 1 |
| Zorlu, P | 1 |
| Dogan, B | 1 |
| Acar, M | 1 |
| Fukunaga, Y | 1 |
| Izawa-Ishizawa, Y | 1 |
| Horinouchi, Y | 1 |
| Sairyo, E | 1 |
| Ikeda, Y | 1 |
| Ishizawa, K | 1 |
| Tsuchiya, K | 1 |
| Abe, Y | 1 |
| Hashimoto, I | 1 |
| Tamaki, T | 1 |
| Liu, W | 1 |
| Shimada, M | 1 |
| Xiao, J | 2 |
| Hu, D | 1 |
| Matsumori, A | 1 |
| Rinker, B | 1 |
| Fink, BF | 1 |
| Barry, NG | 1 |
| Fife, JA | 1 |
| Milan, ME | 1 |
| Yang, YT | 1 |
| Whiteman, M | 1 |
| Gieseg, SP | 1 |
| Chen, Q | 1 |
| Guo, F | 1 |
| Liu, S | 1 |
| Wang, C | 1 |
| Snowise, S | 1 |
| Stone, PR | 1 |
| Chamley, LW | 1 |
| Lobner, D | 1 |
| Ali, C | 1 |
| Jacques, D | 1 |
| Bkaily, G | 1 |
| Jasmin, G | 1 |
| D'Orléans-Juste, P | 1 |
| Chahine, M | 1 |
| Senoo, Y | 1 |
| Murakami, T | 1 |
| Kawakami, S | 1 |
| Teramoto, S | 1 |
| Ganguly, PK | 1 |
| Srivastava, LM | 1 |
| Bora, PS | 1 |
| Gupta, MP | 1 |
| Seth, SD | 1 |
| Caraher, EM | 1 |
| Newsholme, P | 1 |
| Widdowson, PS | 1 |
| Gyte, A | 1 |
| Upton, R | 1 |
| Smith, JC | 1 |
| Pitts, M | 1 |
| Moores, R | 1 |
| Wyatt, I | 1 |
| Leski, ML | 1 |
| Valentine, SL | 1 |
| Coyle, JT | 1 |
| Yamamoto, Y | 1 |
| Ikegaki, I | 1 |
| Sasaki, Y | 1 |
| Uchida, T | 1 |
| Wang, L | 1 |
| Sun, J | 1 |
| Li, L | 1 |
| Harbour, C | 1 |
| Mears, D | 1 |
| Koutalistras, N | 1 |
| Sheil, AG | 1 |
| Hong, JH | 1 |
| Hur, KC | 1 |
| Chung, JM | 1 |
| Tanaka, M | 1 |
| Fujiwara, H | 1 |
| Shibata, Y | 1 |
| Kida, M | 1 |
| Suzuka, H | 1 |
| Kimura, K | 1 |
| Kawai, C | 1 |
| Duarte, JA | 1 |
| Soares, JM | 1 |
| Appell, HJ | 1 |
| Hira, M | 1 |
| Tajima, S | 1 |
| Sano, S | 1 |
| Morales, JM | 2 |
| Andrés, A | 2 |
| Alvarez, C | 1 |
| Prieto, C | 2 |
| Ortuño, B | 2 |
| Ortuño, T | 1 |
| Paternina, ER | 1 |
| Hernandez Poblete, G | 1 |
| Praga, M | 1 |
| Ruilope, LM | 2 |
| Estenoz, J | 1 |
| Dorado, C | 1 |
| Arenas, J | 1 |
| Fernández-Cruz, L | 1 |
| Rodicio, JL | 1 |
| Vassanelli, C | 1 |
| Menegatti, G | 1 |
| Nidasio, GP | 1 |
| Franceschini, L | 1 |
| Cocco, C | 1 |
| Rizzotti, P | 1 |
| Skrokov, R | 1 |
| Milburn, PB | 1 |
| Heilman, EI | 1 |
| Yoshimi, F | 1 |
| Ishimaru, M | 1 |
| Sodeyama, M | 1 |
| Nagao, T | 1 |
| Kawano, N | 1 |
| Morioka, Y | 1 |
| Kudoh, Y | 1 |
| Hearse, DJ | 1 |
| Maxwell, MP | 1 |
| Yoshida, S | 1 |
| Downey, JM | 1 |
| Yellon, DM | 1 |
| Todd, GL | 1 |
| Sterns, DA | 1 |
| Plambeck, RD | 1 |
| Joekel, CS | 1 |
| Eliot, RS | 1 |
| Reimer, KA | 1 |
| Jennings, RB | 1 |
1 review available for nifedipine and Necrosis
| Article | Year |
|---|---|
Effects of calcium-channel blockers on myocardial preservation during experimental acute myocardial infarction.
Topics: Animals; Calcium Channel Blockers; Collateral Circulation; Coronary Circulation; Coronary Disease; D | 1985 |
1 trial available for nifedipine and Necrosis
| Article | Year |
|---|---|
Calcium antagonist treatment of recipients minimizes early cyclosporine nephrotoxicity in renal transplantation: a prospective randomized trial.
Topics: Adult; Clinical Trials as Topic; Cyclosporins; Female; Graft Survival; Humans; Kidney; Kidney Transp | 1989 |
25 other studies available for nifedipine and Necrosis
| Article | Year |
|---|---|
Successfully treated fingertip necrosis in an infant with primary Raynaud phenomenon.
Topics: Anticoagulants; Drug Therapy, Combination; Enoxaparin; Fingers; Humans; Infant; Male; Necrosis; Nife | 2014 |
Topical application of nitrosonifedipine, a novel radical scavenger, ameliorates ischemic skin flap necrosis in a mouse model.
Topics: Administration, Topical; Animals; Antioxidants; Blotting, Western; Disease Models, Animal; Graft Sur | 2017 |
Nifedipine inhibits the activation of inflammatory and immune reactions in viral myocarditis.
Topics: Animals; Biomarkers; Calcium Channel Blockers; Cardiovirus Infections; Collagen Type I; Disease Mode | 2009 |
The effect of calcium channel blockers on smoking-induced skin flap necrosis.
Topics: Animals; Calcium Channel Blockers; Cotinine; Graft Survival; Male; Necrosis; Nicotine; Nifedipine; R | 2010 |
HOCl causes necrotic cell death in human monocyte derived macrophages through calcium dependent calpain activation.
Topics: Calcimycin; Calcium; Calcium Channel Blockers; Calcium Ionophores; Calpain; Caspase 3; Cyclosporine; | 2012 |
Calcium channel blockers prevent endothelial cell activation in response to necrotic trophoblast debris: possible relevance to pre-eclampsia.
Topics: Adolescent; Adult; Calcium Channel Blockers; Case-Control Studies; Cell Adhesion; Cell Proliferation | 2012 |
Mechanisms of bFGF and NT-4 potentiation of necrotic neuronal death.
Topics: Animals; Apoptosis; Cells, Cultured; Cerebral Cortex; Dactinomycin; Fibroblast Growth Factor 2; Gluc | 2002 |
Isradipine prevents the development of spontaneously occurring cardiac necrosis in cardiomyopathic hamster.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Cardiomyopathy, Dilated; Cricetinae; Is | 2003 |
Changes in systemic redistribution of blood flow by vasodilators.
Topics: Animals; Blood Circulation; Blood Gas Analysis; Blood Pressure; Cardiac Output; Chlorpromazine; Dogs | 1984 |
Nifedipine--a new calcium antagonist in experimental myocardial necrosis.
Topics: Animals; Calcium; Male; Myocardial Infarction; Myocardium; Necrosis; Nifedipine; Propranolol; Pyridi | 1981 |
Investigation into the mechanisms of complement mediated cytotoxicity in pancreatic beta cells.
Topics: Animals; Apoptosis; Benzamides; Cell Death; Cell Line; Complement System Proteins; Culture Media; Gl | 1996 |
L-2-chloropropionic acid-induced cerebellar granule cell necrosis is potentiated by L-type calcium channel antagonists.
Topics: Animals; Aspartic Acid; Body Weight; Calcium Channel Blockers; Cerebellar Diseases; Cerebellum; Drug | 1997 |
L-type voltage-gated calcium channels modulate kainic acid neurotoxicity in cerebellar granule cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Apoptosis; Benzodiazepines; Calcium; Calcium Channel Blockers; | 1999 |
The protein kinase inhibitor fasudil protects against ischemic myocardial injury induced by endothelin-1 in the rabbit.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Movement; Diltiazem; Electrocardiograph | 2000 |
Factors affecting hepatocyte viability and CYPIA1 activity during encapsulation.
Topics: Alginates; Animals; Apoptosis; Biocompatible Materials; Calcium; Calcium Chloride; Calcium Compounds | 2000 |
Potentiation of early necrotic death of glucose-starved pheochromocytoma 12 cells by nerve growth factor.
Topics: Animals; Calcium Channel Blockers; Cell Membrane; Cell Nucleus; Cycloheximide; DNA Fragmentation; Gl | 2000 |
Effects of chronic oral administration of nifedipine and diltiazem on occlusive thrombus of small coronary arteries in (NZW x BXSB)F1 male mice.
Topics: Administration, Oral; Animals; Cicatrix; Coronary Thrombosis; Coronary Vessels; Diltiazem; Hemodynam | 1992 |
Nifedipine diminishes exercise-induced muscle damage in mouse.
Topics: Animals; Calcium Channel Blockers; Male; Mice; Monocytes; Muscles; Necrosis; Nifedipine; Physical Ex | 1992 |
Increased survival length of experimental flap by calcium antagonist nifedipine.
Topics: Animals; Graft Survival; Male; Necrosis; Nifedipine; Rats; Rats, Inbred Strains; Surgical Flaps | 1990 |
Calcium channel blockers and early cyclosporine nephrotoxicity after renal transplantation: a prospective randomized study.
Topics: Adult; Creatinine; Cyclosporins; Female; Graft Rejection; Humans; Kidney Transplantation; Kidney Tub | 1990 |
Comparison of different pharmacological interventions on enzymatic parameters during acute myocardial infarction.
Topics: Adult; Aged; Clinical Enzyme Tests; Creatine Kinase; Dipyridamole; Female; Heart; Heparin; Humans; I | 1987 |
Idiopathic atrophie blanche associated with digital infarction.
Topics: Adult; Female; Humans; Infarction; Necrosis; Nifedipine; Toes; Vasculitis | 1988 |
The effect of nifedipine, a calcium channel blocker, on liver ischemia in dogs.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Dogs; Injections, Intravenous; Ischemia; | 1988 |
Calcium antagonists and evolving myocardial infarction: studies of the effects of nifedipine on tissue ATP, collateral flow and infarct size in the closed chest dog.
Topics: Adenosine Triphosphate; Animals; Collateral Circulation; Coronary Circulation; Dogs; Electrocardiogr | 1986 |
Protective effects of slow channel calcium antagonists on noradrenaline induced myocardial necrosis.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Dogs; Electrocardiography; Female; Heart; Hemodynamics | 1986 |