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nifedipine and Myotonic Dystrophy

nifedipine has been researched along with Myotonic Dystrophy in 3 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Myotonic Dystrophy: Neuromuscular disorder characterized by PROGRESSIVE MUSCULAR ATROPHY; MYOTONIA, and various multisystem atrophies. Mild INTELLECTUAL DISABILITY may also occur. Abnormal TRINUCLEOTIDE REPEAT EXPANSION in the 3' UNTRANSLATED REGIONS of DMPK PROTEIN gene is associated with Myotonic Dystrophy 1. DNA REPEAT EXPANSION of zinc finger protein-9 gene intron is associated with Myotonic Dystrophy 2.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with nifedipine delayed the time of the peak plasma hormone responses after naloxone [ACTH, 32."2.67Altered hypothalamic-pituitary-adrenal axis responsiveness in myotonic dystrophy: in vivo evidence for abnormal dihydropyridine-insensitive calcium transport. ( Crosbie, GV; Grice, JE; Hockings, GI; Jackson, RV; Walters, MM, 1993)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hockings, GI1
Grice, JE1
Crosbie, GV1
Walters, MM1
Jackson, RV1
Benders, AA1
Groenen, PJ1
Oerlemans, FT1
Veerkamp, JH1
Wieringa, B1
Grant, R1
Sutton, DL1
Behan, PO1
Ballantyne, JP1

Trials

2 trials available for nifedipine and Myotonic Dystrophy

ArticleYear
Altered hypothalamic-pituitary-adrenal axis responsiveness in myotonic dystrophy: in vivo evidence for abnormal dihydropyridine-insensitive calcium transport.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:6

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Biological Transport; Calcium; Child; Dihydropyridin

1993
Nifedipine in the treatment of myotonia in myotonic dystrophy.
    Journal of neurology, neurosurgery, and psychiatry, 1987, Volume: 50, Issue:2

    Topics: Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Humans; Male; Muscle Contraction

1987

Other Studies

1 other study available for nifedipine and Myotonic Dystrophy

ArticleYear
Myotonic dystrophy protein kinase is involved in the modulation of the Ca2+ homeostasis in skeletal muscle cells.
    The Journal of clinical investigation, 1997, Sep-15, Volume: 100, Issue:6

    Topics: Acetylcholine; Animals; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cells, Cultured; Ho

1997